Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulog LtbR - Frankineae/Propionibacterineae/Pseudonocardiaceae

Properties
Regulator type: Transcription factor
Regulator family: IclR
Regulation mode: repressor
Biological process: Leucine biosynthesis
Effector:
Phylum: Actinobacteria
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 24 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Acidothermus cellulolyticus 11B 3 2
Nocardioides sp. JS614 3 2
Propionibacterium acnes KPA171202
Actinosynnema mirum DSM 43827 3 2
Saccharomonospora viridis DSM 43017 3 2
Saccharopolyspora erythraea NRRL 2338 3 2
Nakamurella multipartita DSM 44233 3 2
Frankia sp. CcI3 3 2
Frankia sp. EAN1pec 3 2
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
leuC
*
Acidothermus cellulolyticus 11B

Site:
position = -43
score = 4.94733
sequence = GATCTCACAATGTGAGACG

Gene: Acel_1591: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
*
Nocardioides sp. JS614

Site:
position = -99
score = 5.09769
sequence = CGTCTCAGATCATGGGATG

Gene: Noca_3298: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
 2
Propionibacterium acnes KPA171202

Gene: PPA1362: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)

Gene: PPA1363: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
*
Actinosynnema mirum DSM 43827

Site:
position = -86
score = 4.42576
sequence = TGTCCCACAAGCCGATACT

Site:
position = -65
score = 4.36398
sequence = CTTCCCATTGACTGGGAAG

Gene: Amir_6006: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
*
Saccharomonospora viridis DSM 43017

Site:
position = -100
score = 4.48921
sequence = TGTCCCACAAAGCGATACT

Site:
position = -79
score = 4.42775
sequence = AATCTCGCGATTTGGGATA

Gene: Svir_09060: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
*
Saccharopolyspora erythraea NRRL 2338

Site:
position = -97
score = 4.37335
sequence = TGTCCCACGTACCGATACT

Site:
position = -76
score = 4.6568
sequence = CTTCTCGTCATCTGGGAAG

Gene: SACE_6144: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
*
Nakamurella multipartita DSM 44233

Site:
position = -98
score = 4.37335
sequence = TGTCCCATGAGGCGATACT

Site:
position = -77
score = 4.90737
sequence = ATTCCCACATAGTGAGATG

Gene: Namu_1478: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
*
Frankia sp. CcI3

Site:
position = -78
score = 5.05224
sequence = CATCCCACATCATGAGACA

Gene: Francci3_3621: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
*
Frankia sp. EAN1pec

Site:
position = -154
score = 4.93302
sequence = CATCTCATCTCCTGAGATG

Gene: Franean1_1113: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
leuD
 
Acidothermus cellulolyticus 11B

Gene: Acel_1590: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
 
Nocardioides sp. JS614

Gene: Noca_3297: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
 
Propionibacterium acnes KPA171202

Gene: PPA1361: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
 
Actinosynnema mirum DSM 43827

Gene: Amir_6005: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
 
Saccharomonospora viridis DSM 43017

Gene: Svir_09070: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
 
Saccharopolyspora erythraea NRRL 2338

Gene: SACE_6143: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
 
Nakamurella multipartita DSM 44233

Gene: Namu_1479: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
 
Frankia sp. CcI3

Gene: Francci3_3620: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
 
Frankia sp. EAN1pec

Gene: Franean1_1114: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
 
CRON 2.
ltbR
*
Acidothermus cellulolyticus 11B

Site:
position = -32
score = 4.94733
sequence = CGTCTCACATTGTGAGATC

Gene: Acel_1592: Leucine biosynthesis transcriptional regulator LtbR, IclR family
*
Nocardioides sp. JS614

Site:
position = -32
score = 5.09769
sequence = CATCCCATGATCTGAGACG

Gene: Noca_3299: Leucine biosynthesis transcriptional regulator LtbR, IclR family
 
Propionibacterium acnes KPA171202

Gene: PPA1364: Leucine biosynthesis transcriptional regulator LtbR, IclR family
*
Actinosynnema mirum DSM 43827

Site:
position = -32
score = 4.36398
sequence = CTTCCCAGTCAATGGGAAG

Site:
position = -11
score = 4.42576
sequence = AGTATCGGCTTGTGGGACA

Gene: Amir_6007: Leucine biosynthesis transcriptional regulator LtbR, IclR family
*
Saccharomonospora viridis DSM 43017

Site:
position = -107
score = 4.42775
sequence = TATCCCAAATCGCGAGATT

Site:
position = -86
score = 4.48921
sequence = AGTATCGCTTTGTGGGACA

Gene: Svir_09050: Leucine biosynthesis transcriptional regulator LtbR, IclR family
*
Saccharopolyspora erythraea NRRL 2338

Site:
position = -80
score = 4.6568
sequence = CTTCCCAGATGACGAGAAG

Site:
position = -59
score = 4.37335
sequence = AGTATCGGTACGTGGGACA

Gene: SACE_6145: Leucine biosynthesis transcriptional regulator LtbR, IclR family
*
Nakamurella multipartita DSM 44233

Site:
position = -32
score = 4.90737
sequence = CATCTCACTATGTGGGAAT

Site:
position = -11
score = 4.37335
sequence = AGTATCGCCTCATGGGACA

Gene: Namu_1477: Leucine biosynthesis transcriptional regulator LtbR, IclR family
*
Frankia sp. CcI3

Site:
position = -32
score = 5.05224
sequence = TGTCTCATGATGTGGGATG

Gene: Francci3_3622: Leucine biosynthesis transcriptional regulator LtbR, IclR family
*
Frankia sp. EAN1pec

Site:
position = 79
score = 4.93302
sequence = CATCTCAGGAGATGAGATG

Gene: Franean1_1112: Leucine biosynthesis transcriptional regulator LtbR, IclR family
Leucine biosynthesis transcriptional regulator LtbR, IclR family
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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