Regulog KdgR - Thermotogales

Properties
Regulator type:	Transcription factor
Regulator family:	IclR
Regulation mode:	repressor
Biological process:	Glucuronate utilization
Effector:	2-keto-3-deoxygluconate
Phylum:	Thermotogae
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 26 sites [see more]

Member of regulog collections

By taxonomy - Thermotogales
By trascription factor - KdgR
By TF family - IclR
By effector - 2-keto-3-deoxygluconate
By pathway - Glucuronate utilization

Statistics of regulated genes
Genome	Genes	Operons
Thermotoga maritima MSB8	19	6
Thermotoga sp. RQ2	10	4
Thermotoga neapolitana DSM 4359	11	4
Thermotoga petrophila RKU-1	19	6
Thermotoga naphthophila RKU-10	19	6
Thermotoga lettingae TMO
Thermosipho africanus TCF52B
Thermosipho melanesiensis BI429
Fervidobacterium nodosum Rt17-B1
Petrotoga mobilis SJ95
Thermotogales bacterium TBF 19.5.1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes												Function

CRON 1.
uxaC	* Thermotoga maritima MSB8 Site: position = -32 score = 5.88409 sequence = TGAGAAAACCATTTTCAAA Gene: TM0064: Uronate isomerase (EC 5.3.1.12)	* Thermotoga sp. RQ2 Site: position = -32 score = 5.88409 sequence = TGAGAAAACCATTTTCAAA Gene: TRQ2_0883: Uronate isomerase (EC 5.3.1.12)	* Thermotoga neapolitana DSM 4359 Site: position = -33 score = 6.1257 sequence = TGAGAAAATCATTTTCACA Gene: CTN_0630: Uronate isomerase (EC 5.3.1.12)	* Thermotoga petrophila RKU-1 Site: position = -32 score = 5.88409 sequence = TGAGAAAACCATTTTCAAA Gene: Tpet_0860: Uronate isomerase (EC 5.3.1.12)	* Thermotoga naphthophila RKU-10 Site: position = -32 score = 5.88409 sequence = TGAGAAAACCATTTTCAAA Gene: Tnap_0694: Uronate isomerase (EC 5.3.1.12)	Thermotoga lettingae TMO	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Uronate isomerase (EC 5.3.1.12)
TM0063	Thermotoga maritima MSB8 Gene: TM0063: hypothetical protein	Thermotoga sp. RQ2 Gene: TRQ2_0884: hypothetical protein	Thermotoga neapolitana DSM 4359 Gene: CTN_0631: hypothetical protein	Thermotoga petrophila RKU-1 Gene: Tpet_0861: hypothetical protein	Thermotoga naphthophila RKU-10 Gene: Tnap_0693: hypothetical protein	Thermotoga lettingae TMO	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	hypothetical protein

CRON 2.
CTN_1813	Thermotoga maritima MSB8	Thermotoga sp. RQ2	* Thermotoga neapolitana DSM 4359 Site: position = -191 score = 5.86065 sequence = TGTGAAAAAGGCTTTCAAA Gene: CTN_0633: Transposase, IS605 OrfB family	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Transposase, IS605 OrfB family
xtpF	* Thermotoga maritima MSB8 Site: position = -199 score = 6.01104 sequence = TGTGAAAGGAACTTTCAAA Gene: TM0060: Xylan oligosaccharide ABC transporter, permease component 1	* Thermotoga sp. RQ2 Site: position = -199 score = 6.01104 sequence = TGTGAAAGGAACTTTCAAA Gene: TRQ2_0886: Xylan oligosaccharide ABC transporter, permease component 1	Thermotoga neapolitana DSM 4359 Gene: CTN_0634: Xylan oligosaccharide ABC transporter, permease component 1	* Thermotoga petrophila RKU-1 Site: position = -199 score = 6.01104 sequence = TGTGAAAGGAACTTTCAAA Gene: Tpet_0864: Xylan oligosaccharide ABC transporter, permease component 1	* Thermotoga naphthophila RKU-10 Site: position = -198 score = 6.01104 sequence = TGTGAAAGGAACTTTCAAA Gene: Tnap_0690: Xylan oligosaccharide ABC transporter, permease component 1	Thermotoga lettingae TMO	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Xylan oligosaccharide ABC transporter, permease component 1
xtpG	Thermotoga maritima MSB8 Gene: TM0059: Xylan oligosaccharide ABC transporter, permease component 2	Thermotoga sp. RQ2 Gene: TRQ2_0887: Xylan oligosaccharide ABC transporter, permease component 2	Thermotoga neapolitana DSM 4359 Gene: CTN_0635: Xylan oligosaccharide ABC transporter, permease component 2	Thermotoga petrophila RKU-1 Gene: Tpet_0865: Xylan oligosaccharide ABC transporter, permease component 2	Thermotoga naphthophila RKU-10 Gene: Tnap_0689: Xylan oligosaccharide ABC transporter, permease component 2	Thermotoga lettingae TMO	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Xylan oligosaccharide ABC transporter, permease component 2
xtpK	Thermotoga maritima MSB8 Gene: TM0058: Xylan oligosaccharide ABC transporter, ATP-binding protein 1	Thermotoga sp. RQ2 Gene: TRQ2_0888: Xylan oligosaccharide ABC transporter, ATP-binding protein 1	Thermotoga neapolitana DSM 4359 Gene: CTN_0636: Xylan oligosaccharide ABC transporter, ATP-binding protein 1	Thermotoga petrophila RKU-1 Gene: Tpet_0866: Xylan oligosaccharide ABC transporter, ATP-binding protein 1	Thermotoga naphthophila RKU-10 Gene: Tnap_0688: Xylan oligosaccharide ABC transporter, ATP-binding protein 1	Thermotoga lettingae TMO	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Xylan oligosaccharide ABC transporter, ATP-binding protein 1
xtpL	Thermotoga maritima MSB8 Gene: TM0057: Xylan oligosaccharide ABC transporter, ATP-binding protein 2	Thermotoga sp. RQ2 Gene: TRQ2_0889: Xylan oligosaccharide ABC transporter, ATP-binding protein 2	Thermotoga neapolitana DSM 4359 Gene: CTN_0637: Xylan oligosaccharide ABC transporter, ATP-binding protein 2	Thermotoga petrophila RKU-1 Gene: Tpet_0867: Xylan oligosaccharide ABC transporter, ATP-binding protein 2	Thermotoga naphthophila RKU-10 Gene: Tnap_0687: Xylan oligosaccharide ABC transporter, ATP-binding protein 2	Thermotoga lettingae TMO	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Xylan oligosaccharide ABC transporter, ATP-binding protein 2
xtpE	Thermotoga maritima MSB8 Gene: TM0056: Xylan oligosaccharide ABC transporter, substrate-binding component	Thermotoga sp. RQ2 Gene: TRQ2_0890: Xylan oligosaccharide ABC transporter, substrate-binding component	Thermotoga neapolitana DSM 4359 Gene: CTN_0638: Xylan oligosaccharide ABC transporter, substrate-binding component	Thermotoga petrophila RKU-1 Gene: Tpet_0868: Xylan oligosaccharide ABC transporter, substrate-binding component	Thermotoga naphthophila RKU-10 Gene: Tnap_0686: Xylan oligosaccharide ABC transporter, substrate-binding component	Thermotoga lettingae TMO	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Xylan oligosaccharide ABC transporter, substrate-binding component
aguA	Thermotoga maritima MSB8 Gene: TM0055: Alpha-glucuronidase (EC 3.2.1.139)	Thermotoga sp. RQ2 Gene: TRQ2_0891: Alpha-glucuronidase (EC 3.2.1.139)	Thermotoga neapolitana DSM 4359 Gene: CTN_0639: Alpha-glucuronidase (EC 3.2.1.139)	Thermotoga petrophila RKU-1 Gene: Tpet_0869: Alpha-glucuronidase (EC 3.2.1.139)	Thermotoga naphthophila RKU-10 Gene: Tnap_0685: Alpha-glucuronidase (EC 3.2.1.139)	Thermotoga lettingae TMO	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Alpha-glucuronidase (EC 3.2.1.139)

CRON 3.
xynA1	* Thermotoga maritima MSB8 Site: position = -138 score = 6.01104 sequence = TTTGAAAGTTCCTTTCACA Gene: TM0061: Endo-1,4-beta-xylanase A precursor (EC 3.2.1.8)	* Thermotoga sp. RQ2 Site: position = -138 score = 6.01104 sequence = TTTGAAAGTTCCTTTCACA Gene: TRQ2_0885: Endo-1,4-beta-xylanase A precursor (EC 3.2.1.8)	* Thermotoga neapolitana DSM 4359 Site: position = -91 score = 5.86065 sequence = TTTGAAAGCCTTTTTCACA Gene: CTN_0632: Endo-1,4-beta-xylanase A precursor (EC 3.2.1.8)	* Thermotoga petrophila RKU-1 Site: position = -139 score = 6.01104 sequence = TTTGAAAGTTCCTTTCACA Gene: Tpet_0863: Endo-1,4-beta-xylanase A precursor (EC 3.2.1.8)	* Thermotoga naphthophila RKU-10 Site: position = -138 score = 6.01104 sequence = TTTGAAAGTTCCTTTCACA Gene: Tnap_0691: Endo-1,4-beta-xylanase A precursor (EC 3.2.1.8)	Thermotoga lettingae TMO	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Endo-1,4-beta-xylanase A precursor (EC 3.2.1.8)
cenC	Thermotoga maritima MSB8 Gene: TM0062: Carbohydrate-binding CenC domain protein	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1 Gene: Tpet_0862: Carbohydrate-binding CenC domain protein	Thermotoga naphthophila RKU-10 Gene: Tnap_0692: Carbohydrate-binding CenC domain protein	Thermotoga lettingae TMO	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Carbohydrate-binding CenC domain protein

CRON 4.
kdgR	* Thermotoga maritima MSB8 Site: position = -88 score = 5.88409 sequence = TTTGAAAATGGTTTTCTCA Gene: TM0065: Predicted 2-keto-3-deoxygluconate-responsive regulator of glucuronate utilization, IclR family	* Thermotoga sp. RQ2 Site: position = -88 score = 5.88409 sequence = TTTGAAAATGGTTTTCTCA Gene: TRQ2_0882: Predicted 2-keto-3-deoxygluconate-responsive regulator of glucuronate utilization, IclR family	* Thermotoga neapolitana DSM 4359 Site: position = -48 score = 6.1257 sequence = TGTGAAAATGATTTTCTCA Gene: CTN_0629: Predicted 2-keto-3-deoxygluconate-responsive regulator of glucuronate utilization, IclR family	* Thermotoga petrophila RKU-1 Site: position = -88 score = 5.88409 sequence = TTTGAAAATGGTTTTCTCA Gene: Tpet_0859: Predicted 2-keto-3-deoxygluconate-responsive regulator of glucuronate utilization, IclR family	* Thermotoga naphthophila RKU-10 Site: position = -88 score = 5.88409 sequence = TTTGAAAATGGTTTTCTCA Gene: Tnap_0695: Predicted 2-keto-3-deoxygluconate-responsive regulator of glucuronate utilization, IclR family	Thermotoga lettingae TMO	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Predicted 2-keto-3-deoxygluconate-responsive regulator of glucuronate utilization, IclR family

CRON 5.
xloE	* Thermotoga maritima MSB8 Site: position = -135 score = 5.19291 sequence = TTTGAAATAATCTTTTACA Gene: TM0071: Xylose oligosaccharides ABC transporter, sugar-binding protein	Thermotoga sp. RQ2 Gene: TRQ2_0876: Xylose oligosaccharides ABC transporter, sugar-binding protein	Thermotoga neapolitana DSM 4359 Gene: CTN_0622: Xylose oligosaccharides ABC transporter, sugar-binding protein	* Thermotoga petrophila RKU-1 Site: position = -136 score = 5.19291 sequence = TTTGAAATAATCTTTTACA Gene: Tpet_0853: Xylose oligosaccharides ABC transporter, sugar-binding protein	* Thermotoga naphthophila RKU-10 Site: position = -135 score = 5.19291 sequence = TTTGAAATAATCTTTTACA Gene: Tnap_0701: Xylose oligosaccharides ABC transporter, sugar-binding protein	Thermotoga lettingae TMO Gene: Tlet_0350: Xylose oligosaccharides ABC transporter, sugar-binding protein	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Xylose oligosaccharides ABC transporter, sugar-binding protein
xloF	Thermotoga maritima MSB8 Gene: TM0072: Xylose oligosaccharides ABC transporter, permease protein 1	Thermotoga sp. RQ2 Gene: TRQ2_0875: Xylose oligosaccharides ABC transporter, permease protein 1	Thermotoga neapolitana DSM 4359 Gene: CTN_0621: Xylose oligosaccharides ABC transporter, permease protein 1	Thermotoga petrophila RKU-1 Gene: Tpet_0852: Xylose oligosaccharides ABC transporter, permease protein 1	Thermotoga naphthophila RKU-10 Gene: Tnap_0702: Xylose oligosaccharides ABC transporter, permease protein 1	Thermotoga lettingae TMO Gene: Tlet_0351: Xylose oligosaccharides ABC transporter, permease protein 1	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Xylose oligosaccharides ABC transporter, permease protein 1
xloG	Thermotoga maritima MSB8 Gene: TM0073: Xylose oligosaccharides ABC transporter, permease protein 2	Thermotoga sp. RQ2 Gene: TRQ2_0874: Xylose oligosaccharides ABC transporter, permease protein 2	Thermotoga neapolitana DSM 4359 Gene: CTN_0620: Xylose oligosaccharides ABC transporter, permease protein 2	Thermotoga petrophila RKU-1 Gene: Tpet_0851: Xylose oligosaccharides ABC transporter, permease protein 2	Thermotoga naphthophila RKU-10 Gene: Tnap_0703: Xylose oligosaccharides ABC transporter, permease protein 2	Thermotoga lettingae TMO Gene: Tlet_0352: Xylose oligosaccharides ABC transporter, permease protein 2	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Xylose oligosaccharides ABC transporter, permease protein 2
xloK	Thermotoga maritima MSB8 Gene: TM0074: Xylose oligosaccharides ABC transporter, ATP-binding protein 1	Thermotoga sp. RQ2 Gene: TRQ2_0873: Xylose oligosaccharides ABC transporter, ATP-binding protein 1	Thermotoga neapolitana DSM 4359 Gene: CTN_0619: Xylose oligosaccharides ABC transporter, ATP-binding protein 1	Thermotoga petrophila RKU-1 Gene: Tpet_0850: Xylose oligosaccharides ABC transporter, ATP-binding protein 1	Thermotoga naphthophila RKU-10 Gene: Tnap_0704: Xylose oligosaccharides ABC transporter, ATP-binding protein 1	Thermotoga lettingae TMO Gene: Tlet_0353: Xylose oligosaccharides ABC transporter, ATP-binding protein 1	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Xylose oligosaccharides ABC transporter, ATP-binding protein 1
xloL	Thermotoga maritima MSB8 Gene: TM0075: Xylose oligosaccharides ABC transporter, ATP-binding protein 2	Thermotoga sp. RQ2 Gene: TRQ2_0872: Xylose oligosaccharides ABC transporter, ATP-binding protein 2	Thermotoga neapolitana DSM 4359 Gene: CTN_0618: Xylose oligosaccharides ABC transporter, ATP-binding protein 2	Thermotoga petrophila RKU-1 Gene: Tpet_0849: Xylose oligosaccharides ABC transporter, ATP-binding protein 2	Thermotoga naphthophila RKU-10 Gene: Tnap_0705: Xylose oligosaccharides ABC transporter, ATP-binding protein 2	Thermotoga lettingae TMO Gene: Tlet_0354: Xylose oligosaccharides ABC transporter, ATP-binding protein 2	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Xylose oligosaccharides ABC transporter, ATP-binding protein 2
xyl3	Thermotoga maritima MSB8 Gene: TM0076: Beta-xylosidase (EC 3.2.1.37)	Thermotoga sp. RQ2 Gene: TRQ2_0871: Beta-xylosidase (EC 3.2.1.37)	Thermotoga neapolitana DSM 4359 Gene: CTN_0616: Beta-xylosidase (EC 3.2.1.37)	Thermotoga petrophila RKU-1 Gene: Tpet_0848: Beta-xylosidase (EC 3.2.1.37)	Thermotoga naphthophila RKU-10 Gene: Tnap_0706: Beta-xylosidase (EC 3.2.1.37)	Thermotoga lettingae TMO Gene: Tlet_0355: Beta-xylosidase (EC 3.2.1.37)	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Beta-xylosidase (EC 3.2.1.37)
axeA	Thermotoga maritima MSB8 Gene: TM0077: Acetyl xylan esterase (EC 3.1.1.41)	Thermotoga sp. RQ2 Gene: TRQ2_0870: Acetyl xylan esterase (EC 3.1.1.41)	Thermotoga neapolitana DSM 4359 Gene: CTN_0615: Acetyl xylan esterase (EC 3.1.1.41)	Thermotoga petrophila RKU-1 Gene: Tpet_0847: Acetyl xylan esterase (EC 3.1.1.41)	Thermotoga naphthophila RKU-10 Gene: Tnap_0707: Acetyl xylan esterase (EC 3.1.1.41)	Thermotoga lettingae TMO Gene: Tlet_0356: Acetyl xylan esterase (EC 3.1.1.41)	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Acetyl xylan esterase (EC 3.1.1.41)

CRON 6.
xynB	* Thermotoga maritima MSB8 Site: position = -103 score = 5.19291 sequence = TGTAAAAGATTATTTCAAA Gene: TM0070: Endo-1,4-beta-xylanase B ( EC 3.2.1.8 )	Thermotoga sp. RQ2 Gene: TRQ2_0877: Endo-1,4-beta-xylanase B ( EC 3.2.1.8 )	Thermotoga neapolitana DSM 4359 Gene: CTN_0623: Endo-1,4-beta-xylanase B ( EC 3.2.1.8 )	* Thermotoga petrophila RKU-1 Site: position = -103 score = 5.19291 sequence = TGTAAAAGATTATTTCAAA Gene: Tpet_0854: Endo-1,4-beta-xylanase B ( EC 3.2.1.8 )	* Thermotoga naphthophila RKU-10 Site: position = -103 score = 5.19291 sequence = TGTAAAAGATTATTTCAAA Gene: Tnap_0700: Endo-1,4-beta-xylanase B ( EC 3.2.1.8 )	Thermotoga lettingae TMO	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Endo-1,4-beta-xylanase B ( EC 3.2.1.8 )

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog KdgR - Thermotogales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --