Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Collection of regulogs for KdgR transcription factor

General statistics
Genomes 42
TF regulogs 4
TF regulons 20
TF binding sites 242

Transcription factor KdgR from the IclR protein family regulates genes involved in utilization of pectin and its derivatives in Gammaproteobacteria. It was originally characterized in Erwinia chrysanthemi as a repressor of the pectin degradation genes, and later it was shown to act as an activator of some genes such as ppsA. Physiological and biochemical studies indicated that an intermediate of pectin catabolism, 2-keto-3-deoxygluconate (KDG), is the main inducing molecule which interacts in vivo and in vitro with KdgR, provoking dissociation of KdgR from its operators. The comparative genomic approach was used to reconstruct orthologous KdgR regulons in the Enterobacteriales, Vibrionales and Pasteurellales lineages of Gammaproteobacteria [11115104, 15528647, 21622752] as well as in Thermotogales.

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Proteobacteria/gamma KdgR - Enterobacteriales 9 (12) 159
Proteobacteria/gamma KdgR - Pasteurellales 2 (9) 17
Proteobacteria/gamma KdgR - Vibrionales 4 (10) 40
Thermotogae KdgR - Thermotogales 5 (11) 26