Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulog LtbR - Mycobacteriaceae

Properties
Regulator type: Transcription factor
Regulator family: IclR
Regulation mode: repressor
Biological process: Leucine biosynthesis
Effector:
Phylum: Actinobacteria
Visualization:
Allows to visualize regulog content in the context of metabolic pathways
Built upon 30 sites [see more]
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Mycobacterium smegmatis str. MC2 155 3 2
Mycobacterium tuberculosis H37Rv 3 2
Mycobacterium abscessus ATCC 19977 3 2
Mycobacterium avium 104 3 2
Mycobacterium marinum M 3 2
Mycobacterium leprae TN
Mycobacterium vanbaalenii PYR-1 3 2
Mycobacterium flavescens PYR-GCK 3 2
Mycobacterium sp. JLS 3 2
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
ltbR
*
Mycobacterium smegmatis str. MC2 155

Site:
position = -32
score = 5.37171
sequence = TATCTCAAAATACGAGACG

Site:
position = -11
score = 4.09662
sequence = AGTATCTCTCTGTGAGAAA

Gene: MSMEG_2386: Leucine and tryptophan biosynthesis transcriptional regulator LtbR, IclR family
*
Mycobacterium tuberculosis H37Rv

Site:
position = -32
score = 5.47798
sequence = CATCTCAAAATACGAGACG

Gene: Rv2989: Leucine and tryptophan biosynthesis transcriptional regulator LtbR, IclR family
*
Mycobacterium abscessus ATCC 19977

Site:
position = -11
score = 4.2726
sequence = AGTATCGTTACGTGAGACA

Site:
position = -32
score = 4.61527
sequence = CGTCTCAATATTTGGAACG

Gene: MAB_3295: Leucine and tryptophan biosynthesis transcriptional regulator LtbR, IclR family
*
Mycobacterium avium 104

Site:
position = -71
score = 5.26493
sequence = GATCTCATAATGCGAGACG

Site:
position = -50
score = 4.87055
sequence = AGTATCTCCTTGTGAGACA

Gene: MAV_3839: Leucine and tryptophan biosynthesis transcriptional regulator LtbR, IclR family
*
Mycobacterium marinum M

Site:
position = -32
score = 5.53157
sequence = CATCTCATAATACGAGACG

Site:
position = -11
score = 4.87055
sequence = AGTATCTCCTTGTGAGACA

Gene: MMAR_1725: Leucine and tryptophan biosynthesis transcriptional regulator LtbR, IclR family
 
Mycobacterium leprae TN
*
Mycobacterium vanbaalenii PYR-1

Site:
position = -32
score = 5.19191
sequence = TGTCTCACAATCTGGGAAG

Site:
position = -11
score = 4.70331
sequence = AATATCTCCTTGTGAGACA

Gene: Mvan_2134: Leucine and tryptophan biosynthesis transcriptional regulator LtbR, IclR family
*
Mycobacterium flavescens PYR-GCK

Site:
position = -11
score = 4.87055
sequence = AGTATCTCCTTGTGAGACA

Site:
position = -32
score = 4.94046
sequence = TTTCTCACATTCTGGGAAG

Gene: Mflv_4228: Leucine and tryptophan biosynthesis transcriptional regulator LtbR, IclR family
*
Mycobacterium sp. JLS

Site:
position = -11
score = 4.42365
sequence = AGTATCTCCCTGTGAGACA

Site:
position = -32
score = 4.90989
sequence = AATCTCACATTGCGGGAGG

Gene: Mjls_1900: Leucine and tryptophan biosynthesis transcriptional regulator LtbR, IclR family
Leucine and tryptophan biosynthesis transcriptional regulator LtbR, IclR family
 
CRON 2.
leuC
*
Mycobacterium smegmatis str. MC2 155

Site:
position = -119
score = 4.09662
sequence = TTTCTCACAGAGAGATACT

Site:
position = -98
score = 5.37171
sequence = CGTCTCGTATTTTGAGATA

Gene: MSMEG_2387: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
*
Mycobacterium tuberculosis H37Rv

Site:
position = -58
score = 5.47798
sequence = CGTCTCGTATTTTGAGATG

Gene: Rv2988c: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
*
Mycobacterium abscessus ATCC 19977

Site:
position = -39
score = 4.61527
sequence = CGTTCCAAATATTGAGACG

Site:
position = -60
score = 4.2726
sequence = TGTCTCACGTAACGATACT

Gene: MAB_3294c: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
*
Mycobacterium avium 104

Site:
position = -94
score = 4.87055
sequence = TGTCTCACAAGGAGATACT

Site:
position = -73
score = 5.26493
sequence = CGTCTCGCATTATGAGATC

Gene: MAV_3838: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
*
Mycobacterium marinum M

Site:
position = -90
score = 4.87055
sequence = TGTCTCACAAGGAGATACT

Site:
position = -69
score = 5.53157
sequence = CGTCTCGTATTATGAGATG

Gene: MMAR_1726: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
 
Mycobacterium leprae TN

Gene: ML1685: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
*
Mycobacterium vanbaalenii PYR-1

Site:
position = -25
score = 5.19191
sequence = CTTCCCAGATTGTGAGACA

Site:
position = -46
score = 4.70331
sequence = TGTCTCACAAGGAGATATT

Gene: Mvan_2135: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
*
Mycobacterium flavescens PYR-GCK

Site:
position = -46
score = 4.87055
sequence = TGTCTCACAAGGAGATACT

Site:
position = -25
score = 4.94046
sequence = CTTCCCAGAATGTGAGAAA

Gene: Mflv_4227: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
*
Mycobacterium sp. JLS

Site:
position = -84
score = 4.42365
sequence = TGTCTCACAGGGAGATACT

Site:
position = -63
score = 4.90989
sequence = CCTCCCGCAATGTGAGATT

Gene: Mjls_1901: 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
leuD
 
Mycobacterium smegmatis str. MC2 155

Gene: MSMEG_2388: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
 
Mycobacterium tuberculosis H37Rv

Gene: Rv2987c: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
 
Mycobacterium abscessus ATCC 19977

Gene: MAB_3293c: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
 
Mycobacterium avium 104

Gene: MAV_3837: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
 
Mycobacterium marinum M

Gene: MMAR_1727: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
 
Mycobacterium leprae TN

Gene: ML1684: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
 
Mycobacterium vanbaalenii PYR-1

Gene: Mvan_2136: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
 
Mycobacterium flavescens PYR-GCK

Gene: Mflv_4226: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
 
Mycobacterium sp. JLS

Gene: Mjls_1902: 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
3-isopropylmalate dehydratase small subunit (EC 4.2.1.33)
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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