Collection of regulogs for DtxR transcription factor family

DtxR family of transcription factors (also known as DtxR/MntR) includes metal ion-dependent regulators that maintain the iron and manganese homeostasis both in Bacteria and Archaea [22297991]. The DtxR-family regulators usually act as transcriptional repressors, while in some cases they can also function as transcriptional activators [16585752]. Ferrous iron and/or manganese serve as co-repressors for metalloregulators [11282473]. DtxR-family regulators contain an N-terminal HTH DNA binding domain (PF01325) and a C-terminal domain (PF02742) that is responsible for metal ion binding and dimerization.