Regulog Cobalamin - Clostridiaceae

Properties
Regulator type:	RNA regulatory element
Name:	Cobalamin
RFAM:	RF00174
Regulation mode:
Biological process:	Cobalamin biosynthesis
Effector:	Adenosylcobalamin
Phylum:	Firmicutes

Member of regulog collections

By taxonomy - Clostridiaceae
By RNA motif - Cobalamin
By effector - Adenosylcobalamin
By pathway - Cobalamin biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Clostridium kluyveri DSM 555	4	1
Clostridium sp. SS2/1	5	1
Clostridium cellulolyticum H10	25	2
Clostridium phytofermentans ISDg	32	4
Clostridium tetani E88	45	8
Clostridium acetobutylicum ATCC 824	25	2
Clostridium botulinum A str. ATCC 3502	42	1
Clostridium novyi NT	25	3
Clostridium perfringens ATCC 13124	24	4
Clostridium difficile 630	25	3
Clostridium beijerincki NCIMB 8052	9	1
Clostridium sp. OhILAs	43	8
Clostridium sp. L2-50
Clostridium scindens ATCC 35704	12	2
Clostridium nexile DSM 1787	6	1
Clostridium leptum DSM 753	6	1
Clostridium hiranonis DSM 13275	4	1
Clostridium butyricum 5521	18	2
Clostridium bolteae ATCC BAA-613	6	1
Clostridium bartlettii DSM 16795	36	4

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																					Function

CRON 1.
THA_169	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	* Clostridium sp. OhILAs Site: position = -356 score = 106.08 sequence = TAAATAGAATGACCA... Gene: Clos_0622: YidE/YbjL duplication	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	YidE/YbjL duplication
sucC	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_0623: Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5)
sucD	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_0624: Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5)
Clos_0625	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_0625: Phytochrome-like protein; Cph2	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Phytochrome-like protein; Cph2

CRON 2.
dppB	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_0574: inner membrane ABC transporter permease protein YddR	Clostridium bolteae ATCC BAA-613	* Clostridium bartlettii DSM 16795 Site: position = -480 score = 108.18 sequence = TGAATTGAATATTGT... Gene: CLOBAR_00841: inner membrane ABC transporter permease protein YddR	inner membrane ABC transporter permease protein YddR
dppC	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_0573: inner membrane ABC transporter permease protein YddQ	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00840: inner membrane ABC transporter permease protein YddQ	inner membrane ABC transporter permease protein YddQ
dppA	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_0572: putative ABC-type dipeptide/nickel transport system, periplasmic component	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00839: putative ABC-type dipeptide/nickel transport system, periplasmic component	putative ABC-type dipeptide/nickel transport system, periplasmic component
dppD	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_0571: oligopeptide transport ATP-binding protein AppD	Clostridium bolteae ATCC BAA-613	2 Clostridium bartlettii DSM 16795 Gene: CLOBAR_00838: oligopeptide transport ATP-binding protein AppD Gene: CLOBAR_00837: oligopeptide transport ATP-binding protein AppD	oligopeptide transport ATP-binding protein AppD

CRON 3.
cobW	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO1492: Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	* Clostridium scindens ATCC 35704 Site: position = -248 score = 109.68 sequence = TAATAACAGTAACGT... Gene: CLOSCI_02169: Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family
mtbC	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO1494: Dimethylamine corrinoid protein 2	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	2 Clostridium scindens ATCC 35704 Gene: CLOSCI_02168: Dimethylamine corrinoid protein 2 Gene: CLOSCI_02165: Dimethylamine corrinoid protein 2	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Dimethylamine corrinoid protein 2
hemE	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	2 Clostridium scindens ATCC 35704 Gene: CLOSCI_02167: hypothetical protein Gene: CLOSCI_02162: hypothetical protein	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	hypothetical protein
CBO1493	Clostridium kluyveri DSM 555 Gene: CKL_0711: Methylcobalamin:coenzyme M methyltransferase, methylamine-specific	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO1493: Methylcobalamin:coenzyme M methyltransferase, methylamine-specific	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_02166: Methylcobalamin:coenzyme M methyltransferase, methylamine-specific	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Methylcobalamin:coenzyme M methyltransferase, methylamine-specific
mtbA	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO1495: Methylcobalamin:coenzyme M methyltransferase, methylamine-specific	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_02164: Methylcobalamin:coenzyme M methyltransferase, methylamine-specific	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Methylcobalamin:coenzyme M methyltransferase, methylamine-specific
CBO1491	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_3201: probable electron transfer protein	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO1491: probable electron transfer protein	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_02163: probable electron transfer protein	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	2 Clostridium bartlettii DSM 16795 Gene: CLOBAR_01843: probable electron transfer protein Gene: CLOBAR_01844: probable electron transfer protein	probable electron transfer protein

CRON 4.
CTC00778	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	* Clostridium tetani E88 Site: position = -405 score = 115.73 sequence = TAAATATTTATTTAT... Gene: CTC00778: hypothetical protein	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	hypothetical protein

CRON 5.
dppA	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	* Clostridium tetani E88 Site: position = -305 score = 121.66 sequence = ATATTATGAATTTTT... Gene: CTC01400: periplasmic dipeptide transport protein precursor	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	periplasmic dipeptide transport protein precursor
dppB	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC01401: transport system permease, nickel or dipeptide	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	transport system permease, nickel or dipeptide
dppC	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC01402: transport system permease, dipeptide or nickel	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	transport system permease, dipeptide or nickel
dppD	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC01403: Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1)	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1)
dppF	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC01404: peptide transport ATP-binding protein	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	peptide transport ATP-binding protein
CTC01405	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC01405: Methyltransferase (EC 2.1.1.-)	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Methyltransferase (EC 2.1.1.-)

CRON 6.
cbiP	Clostridium kluyveri DSM 555 Gene: CKL_0721: Cobyric acid synthase	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1284: Cobyric acid synthase	Clostridium phytofermentans ISDg Gene: null: Cobyric acid synthase	* Clostridium tetani E88 Site: position = -400 score = 126.42 sequence = GAATATGAAAATATT... Gene: CTC00720: Cobyric acid synthase	Clostridium acetobutylicum ATCC 824 Gene: CAC1374: Cobyric acid synthase	* Clostridium botulinum A str. ATCC 3502 Site: position = -323 score = 122.69 sequence = TTTAATAAAAAGATT... Gene: CBO0914: Cobyric acid synthase	Clostridium novyi NT Gene: NT01CX_2081: Cobyric acid synthase	Clostridium perfringens ATCC 13124 Gene: CPF_1300: Cobyric acid synthase	* Clostridium difficile 630 Site: position = -295 score = 102.08 sequence = GAATATTAGATTAAA... Gene: CD3435: Cobyric acid synthase	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1272: Cobyric acid synthase	Clostridium sp. OhILAs Gene: Clos_0863: Cobyric acid synthase	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03605: Cobyric acid synthase	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00695: Cobyric acid synthase	2 Clostridium butyricum 5521 Gene: CBY_3407: Cobyric acid synthase Gene: CBY_0388: Cobyric acid synthase	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01278: Cobyric acid synthase	* Clostridium bartlettii DSM 16795 Site: position = -274 score = 71.78 sequence = AGGGAAAAAGGTACA... Gene: CLOBAR_01422: Cobyric acid synthase	Cobyric acid synthase
cbiB	Clostridium kluyveri DSM 555 Gene: CKL_2910: Adenosylcobinamide-phosphate synthase	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1286: Adenosylcobinamide-phosphate synthase	Clostridium phytofermentans ISDg Gene: null: Adenosylcobinamide-phosphate synthase	Clostridium tetani E88 Gene: CTC00721: Adenosylcobinamide-phosphate synthase	Clostridium acetobutylicum ATCC 824 Gene: CAC0582: Adenosylcobinamide-phosphate synthase	Clostridium botulinum A str. ATCC 3502 Gene: CBO0915: Adenosylcobinamide-phosphate synthase	Clostridium novyi NT Gene: NT01CX_2082: Adenosylcobinamide-phosphate synthase	Clostridium perfringens ATCC 13124 Gene: CPF_1294: Adenosylcobinamide-phosphate synthase	Clostridium difficile 630 Gene: CD3433: Adenosylcobinamide-phosphate synthase	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1268: Adenosylcobinamide-phosphate synthase	* Clostridium sp. OhILAs Site: position = -319 score = 118.45 sequence = ACAAATTAAATAGTT... Gene: Clos_2212: Adenosylcobinamide-phosphate synthase	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03603: Adenosylcobinamide-phosphate synthase	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00697: Adenosylcobinamide-phosphate synthase	Clostridium butyricum 5521 Gene: CBY_3405: Adenosylcobinamide-phosphate synthase	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01280: Adenosylcobinamide-phosphate synthase	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01420: Adenosylcobinamide-phosphate synthase	Adenosylcobinamide-phosphate synthase
cobD	Clostridium kluyveri DSM 555 Gene: CKL_0714: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1287: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	2 Clostridium phytofermentans ISDg Gene: null: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) Gene: null: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Clostridium tetani E88 Gene: CTC00722: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Clostridium acetobutylicum ATCC 824 Gene: CAC1369: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0916: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Clostridium novyi NT Gene: NT01CX_2083: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Clostridium perfringens ATCC 13124 Gene: CPF_1295: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Clostridium difficile 630 Gene: CD3432: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1269: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Clostridium sp. OhILAs Gene: Clos_2211: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03604: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00698: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Clostridium butyricum 5521 Gene: CBY_3406: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01279: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01419: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
cbiM	* Clostridium kluyveri DSM 555 Site: position = -345 score = 89.08 sequence = AATTTAATAATAAAA... Gene: CKL_3429: Substrate-specific component CbiM of cobalt ECF transporter	Clostridium sp. SS2/1	* Clostridium cellulolyticum H10 Site: position = -380 score = 95.57 sequence = TAATAATTAACGATA... Gene: Ccel_1266: Substrate-specific component CbiM of cobalt ECF transporter	Clostridium phytofermentans ISDg Gene: null: Substrate-specific component CbiM of cobalt ECF transporter	Clostridium tetani E88 Gene: CTC00723: Substrate-specific component CbiM of cobalt ECF transporter	* Clostridium acetobutylicum ATCC 824 Site: position = -313 score = 105.44 sequence = TGCTACTAAAATTTG... Gene: CAC1365: Substrate-specific component CbiM of cobalt ECF transporter	Clostridium botulinum A str. ATCC 3502 Gene: CBO0917: Substrate-specific component CbiM of cobalt ECF transporter	* Clostridium novyi NT Site: position = -349 score = 95.81 sequence = AAAATACATACAAAG... Gene: NT01CX_1329: Substrate-specific component CbiM of cobalt ECF transporter	* Clostridium perfringens ATCC 13124 Site: position = -486 score = 93.49 sequence = TTAAATATTTAGAAA... Gene: CPF_0185: Substrate-specific component CbiM of cobalt ECF transporter	* Clostridium difficile 630 Site: position = -373 score = 102.77 sequence = AAATATATAATATTA... Gene: CD0324: Substrate-specific component CbiM of cobalt ECF transporter	Clostridium beijerincki NCIMB 8052 Gene: Cbei_3710: Substrate-specific component CbiM of cobalt ECF transporter	* Clostridium sp. OhILAs Site: position = -432 score = 121.76 sequence = GTAAATAAGAAGCAT... Gene: Clos_1011: Substrate-specific component CbiM of cobalt ECF transporter	Clostridium sp. L2-50	* Clostridium scindens ATCC 35704 Site: position = -376 score = 65.35 sequence = ACTTATTGTGGTCAT... Gene: CLOSCI_03609: Substrate-specific component CbiM of cobalt ECF transporter	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	* Clostridium hiranonis DSM 13275 Site: position = -403 score = 101.91 sequence = GAATATAAATAGTTT... Gene: CLOHIR_01689: Substrate-specific component CbiM of cobalt ECF transporter	* Clostridium butyricum 5521 Site: position = -417 score = 102.37 sequence = CAAAAATATAATTAT... Gene: CBY_1415: Substrate-specific component CbiM of cobalt ECF transporter	Clostridium bolteae ATCC BAA-613	* Clostridium bartlettii DSM 16795 Site: position = -386 score = 114.73 sequence = AGATGAAATGTATAT... Gene: CLOBAR_01388: Substrate-specific component CbiM of cobalt ECF transporter	Substrate-specific component CbiM of cobalt ECF transporter
cbiN	Clostridium kluyveri DSM 555 Gene: CKL_3428: Additional substrate-specific component CbiN of cobalt ECF transporter	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1267: Additional substrate-specific component CbiN of cobalt ECF transporter	Clostridium phytofermentans ISDg Gene: null: Additional substrate-specific component CbiN of cobalt ECF transporter	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC1366: Additional substrate-specific component CbiN of cobalt ECF transporter	Clostridium botulinum A str. ATCC 3502 Gene: CBO0917A: Additional substrate-specific component CbiN of cobalt ECF transporter	Clostridium novyi NT Gene: NT01CX_1330: Additional substrate-specific component CbiN of cobalt ECF transporter	Clostridium perfringens ATCC 13124 Gene: CPF_0186: Additional substrate-specific component CbiN of cobalt ECF transporter	Clostridium difficile 630 Gene: CD0325: Additional substrate-specific component CbiN of cobalt ECF transporter	Clostridium beijerincki NCIMB 8052 Gene: Cbei_3709: Additional substrate-specific component CbiN of cobalt ECF transporter	Clostridium sp. OhILAs Gene: Clos_1012: Additional substrate-specific component CbiN of cobalt ECF transporter	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03610: Additional substrate-specific component CbiN of cobalt ECF transporter	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01690: Additional substrate-specific component CbiN of cobalt ECF transporter	Clostridium butyricum 5521 Gene: CBY_1414: Additional substrate-specific component CbiN of cobalt ECF transporter	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01387: Additional substrate-specific component CbiN of cobalt ECF transporter	Additional substrate-specific component CbiN of cobalt ECF transporter
cbiQ	Clostridium kluyveri DSM 555 Gene: CKL_3427: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1268: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	* Clostridium phytofermentans ISDg Site: position = -371 score = 50.16 sequence = GAAGTTGGGTGCAAT... Gene: null: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Clostridium tetani E88 Gene: CTC00724: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Clostridium acetobutylicum ATCC 824 Gene: CAC1367: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Clostridium botulinum A str. ATCC 3502 Gene: CBO0918: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Clostridium novyi NT Gene: NT01CX_1331: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Clostridium perfringens ATCC 13124 Gene: CPF_0187: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Clostridium difficile 630 Gene: CD0326: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Clostridium beijerincki NCIMB 8052 Gene: Cbei_3712: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Clostridium sp. OhILAs Gene: Clos_1013: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03611: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01691: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Clostridium butyricum 5521 Gene: CBY_1417: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01386: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Transmembrane component CbiQ of energizing module of cobalt ECF transporter
cysG1	Clostridium kluyveri DSM 555 Gene: CKL_2909: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC00726: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Clostridium acetobutylicum ATCC 824 Gene: CAC0096: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0919: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Clostridium novyi NT	Clostridium perfringens ATCC 13124 Gene: CPF_1689: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1284: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_3439: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
hemC	Clostridium kluyveri DSM 555 Gene: CKL_0718: Porphobilinogen deaminase (EC 2.5.1.61)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1277: Porphobilinogen deaminase (EC 2.5.1.61)	2 Clostridium phytofermentans ISDg Gene: null: Porphobilinogen deaminase (EC 2.5.1.61) Gene: null: Porphobilinogen deaminase (EC 2.5.1.61)	Clostridium tetani E88 Gene: CTC00727: Porphobilinogen deaminase (EC 2.5.1.61)	Clostridium acetobutylicum ATCC 824 Gene: CAC0097: Porphobilinogen deaminase (EC 2.5.1.61)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0920: Porphobilinogen deaminase (EC 2.5.1.61)	Clostridium novyi NT Gene: NT01CX_0262: Porphobilinogen deaminase (EC 2.5.1.61)	Clostridium perfringens ATCC 13124 Gene: CPF_1688: Porphobilinogen deaminase (EC 2.5.1.61)	Clostridium difficile 630 Gene: CD3421: Porphobilinogen deaminase (EC 2.5.1.61)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1285: Porphobilinogen deaminase (EC 2.5.1.61)	Clostridium sp. OhILAs Gene: Clos_1327: Porphobilinogen deaminase (EC 2.5.1.61)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00710: Porphobilinogen deaminase (EC 2.5.1.61)	Clostridium butyricum 5521 Gene: CBY_3440: Porphobilinogen deaminase (EC 2.5.1.61)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_02876: Porphobilinogen deaminase (EC 2.5.1.61)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01407: Porphobilinogen deaminase (EC 2.5.1.61)	Porphobilinogen deaminase (EC 2.5.1.61)
cobA-hemD	Clostridium kluyveri DSM 555 Gene: CKL_0719: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1278: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	2 Clostridium phytofermentans ISDg Gene: null: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75) Gene: null: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Clostridium tetani E88 Gene: CTC00728: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Clostridium acetobutylicum ATCC 824 Gene: CAC0098: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0921: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Clostridium novyi NT Gene: NT01CX_0261: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Clostridium perfringens ATCC 13124 Gene: CPF_1687: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Clostridium difficile 630 Gene: CD3420: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1286: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Clostridium sp. OhILAs Gene: Clos_1328: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00711: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Clostridium butyricum 5521 Gene: CBY_3441: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_02875: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01406: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
CBO0922	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0922: hypothetical protein	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	hypothetical protein
hemB	Clostridium kluyveri DSM 555 Gene: CKL_0713: Porphobilinogen synthase (EC 4.2.1.24)	Clostridium sp. SS2/1 Gene: CLOSS21_01705: Porphobilinogen synthase (EC 4.2.1.24)	Clostridium cellulolyticum H10 Gene: Ccel_1279: Porphobilinogen synthase (EC 4.2.1.24)	2 Clostridium phytofermentans ISDg Gene: null: Porphobilinogen synthase (EC 4.2.1.24) Gene: null: Porphobilinogen synthase (EC 4.2.1.24)	Clostridium tetani E88 Gene: CTC00729: Porphobilinogen synthase (EC 4.2.1.24)	Clostridium acetobutylicum ATCC 824 Gene: CAC0100: Porphobilinogen synthase (EC 4.2.1.24)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0923: Porphobilinogen synthase (EC 4.2.1.24)	Clostridium novyi NT Gene: NT01CX_0260: Porphobilinogen synthase (EC 4.2.1.24)	Clostridium perfringens ATCC 13124 Gene: CPF_1686: Porphobilinogen synthase (EC 4.2.1.24)	Clostridium difficile 630 Gene: CD3419: Porphobilinogen synthase (EC 4.2.1.24)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1287: Porphobilinogen synthase (EC 4.2.1.24)	Clostridium sp. OhILAs Gene: Clos_1329: Porphobilinogen synthase (EC 4.2.1.24)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03617: Porphobilinogen synthase (EC 4.2.1.24)	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01522: Porphobilinogen synthase (EC 4.2.1.24)	Clostridium butyricum 5521 Gene: CBY_3442: Porphobilinogen synthase (EC 4.2.1.24)	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01405: Porphobilinogen synthase (EC 4.2.1.24)	Porphobilinogen synthase (EC 4.2.1.24)
cbiA	Clostridium kluyveri DSM 555 Gene: CKL_0722: Cobyrinic acid A,C-diamide synthase	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1283: Cobyrinic acid A,C-diamide synthase	Clostridium phytofermentans ISDg Gene: null: Cobyrinic acid A,C-diamide synthase	Clostridium tetani E88 Gene: CTC00731: Cobyrinic acid A,C-diamide synthase	Clostridium acetobutylicum ATCC 824 Gene: CAC1375: Cobyrinic acid A,C-diamide synthase	Clostridium botulinum A str. ATCC 3502 Gene: CBO0924: Cobyrinic acid A,C-diamide synthase	* Clostridium novyi NT Site: position = -301 score = 119.12 sequence = AAAATTGTATATTAG... Gene: NT01CX_0583: Cobyrinic acid A,C-diamide synthase	Clostridium perfringens ATCC 13124	Clostridium difficile 630 Gene: CD3434: Cobyrinic acid A,C-diamide synthase	Clostridium beijerincki NCIMB 8052 Gene: Cbei_2310: Cobyrinic acid A,C-diamide synthase	* Clostridium sp. OhILAs Site: position = -309 score = 57.4 sequence = AATTTGGAAGCTGGG... Gene: Clos_0862: Cobyrinic acid A,C-diamide synthase	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03597: Cobyrinic acid A,C-diamide synthase	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00696: Cobyrinic acid A,C-diamide synthase	Clostridium butyricum 5521 Gene: CBY_3394: Cobyrinic acid A,C-diamide synthase	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01285: Cobyrinic acid A,C-diamide synthase	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01421: Cobyrinic acid A,C-diamide synthase	Cobyrinic acid A,C-diamide synthase
cbiC	Clostridium kluyveri DSM 555 Gene: CKL_0723: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1285: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Clostridium phytofermentans ISDg Gene: null: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Clostridium tetani E88 Gene: CTC00732: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Clostridium acetobutylicum ATCC 824 Gene: CAC1376: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0925: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Clostridium novyi NT Gene: NT01CX_0582: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Clostridium perfringens ATCC 13124 Gene: CPF_1435: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Clostridium difficile 630 Gene: CD3430: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_2311: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Clostridium sp. OhILAs Gene: Clos_1015: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03606: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00700: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Clostridium butyricum 5521 Gene: CBY_3395: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01277: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01417: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
CBO0926	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0926: CAAX amino terminal protease family	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	CAAX amino terminal protease family
wrbA	2 Clostridium kluyveri DSM 555 Gene: CKL_2875: Iron-sulfur flavoprotein Gene: CKL_3443: Iron-sulfur flavoprotein	Clostridium sp. SS2/1 Gene: CLOSS21_01031: Iron-sulfur flavoprotein	Clostridium cellulolyticum H10 Gene: Ccel_0192: Iron-sulfur flavoprotein	Clostridium phytofermentans ISDg Gene: null: Iron-sulfur flavoprotein	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0927: Iron-sulfur flavoprotein	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_4693: Iron-sulfur flavoprotein	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_00616: Iron-sulfur flavoprotein	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_0932: Iron-sulfur flavoprotein	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00639: Iron-sulfur flavoprotein	Iron-sulfur flavoprotein
Cbei_2684	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0928: HD domain protein	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_2684: HD domain protein	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_03585: HD domain protein	Clostridium bartlettii DSM 16795	HD domain protein
CBO0929	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0929: hypothetical protein	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	hypothetical protein
CBO0930	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0930: Transcriptional regulator, MerR family	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Transcriptional regulator, MerR family
CBO0931	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0931: Acetyltransferase (EC 2.3.1.-)	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_0929: Acetyltransferase (EC 2.3.1.-)	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Acetyltransferase (EC 2.3.1.-)
CD0837	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC3555: Nitroreductase family protein	Clostridium botulinum A str. ATCC 3502 Gene: CBO0933: Nitroreductase family protein	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630 Gene: CD0837: Nitroreductase family protein	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_01710: Nitroreductase family protein	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01882: Nitroreductase family protein	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_04764: Nitroreductase family protein	Clostridium bartlettii DSM 16795	Nitroreductase family protein
CBO0934	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0934: membrane protein	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	membrane protein
CBO0935	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0935: Glutamate-rich protein grpB	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Glutamate-rich protein grpB
cbiD	Clostridium kluyveri DSM 555 Gene: CKL_0724: Cobalt-precorrin-6 synthase, anaerobic	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1270: Cobalt-precorrin-6 synthase, anaerobic	Clostridium phytofermentans ISDg Gene: null: Cobalt-precorrin-6 synthase, anaerobic	Clostridium tetani E88 Gene: CTC00733: Cobalt-precorrin-6 synthase, anaerobic	Clostridium acetobutylicum ATCC 824 Gene: CAC1377: Cobalt-precorrin-6 synthase, anaerobic	Clostridium botulinum A str. ATCC 3502 Gene: CBO0936: Cobalt-precorrin-6 synthase, anaerobic	Clostridium novyi NT Gene: NT01CX_0581: Cobalt-precorrin-6 synthase, anaerobic	Clostridium perfringens ATCC 13124 Gene: CPF_1434: Cobalt-precorrin-6 synthase, anaerobic	Clostridium difficile 630 Gene: CD3429: Cobalt-precorrin-6 synthase, anaerobic	Clostridium beijerincki NCIMB 8052 Gene: Cbei_2312: Cobalt-precorrin-6 synthase, anaerobic	Clostridium sp. OhILAs Gene: Clos_1016: Cobalt-precorrin-6 synthase, anaerobic	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03591: Cobalt-precorrin-6 synthase, anaerobic	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00701: Cobalt-precorrin-6 synthase, anaerobic	Clostridium butyricum 5521 Gene: CBY_3397: Cobalt-precorrin-6 synthase, anaerobic	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01289: Cobalt-precorrin-6 synthase, anaerobic	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01416: Cobalt-precorrin-6 synthase, anaerobic	Cobalt-precorrin-6 synthase, anaerobic
cbiE	Clostridium kluyveri DSM 555 Gene: CKL_0725: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC0584: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0937: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)	Clostridium novyi NT Gene: NT01CX_0580: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)	Clostridium perfringens ATCC 13124 Gene: CPF_1433: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)	Clostridium difficile 630 Gene: CD3428: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_2313: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)	Clostridium sp. OhILAs Gene: Clos_1017: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00702: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)	Clostridium butyricum 5521 Gene: CBY_3398: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01415: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)	Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
CBO0938	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0938: CAAX amino terminal protease family protein	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_02183: CAAX amino terminal protease family protein	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	CAAX amino terminal protease family protein
cbiT	Clostridium kluyveri DSM 555 Gene: CKL_0726: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC1378: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0939: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Clostridium novyi NT Gene: NT01CX_0579: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Clostridium perfringens ATCC 13124 Gene: CPF_1432: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Clostridium difficile 630 Gene: CD3427: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_2314: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Clostridium sp. OhILAs Gene: Clos_1018: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00703: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Clostridium butyricum 5521 Gene: CBY_3399: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01414: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
CBO0940	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0940: hypothetical protein	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	hypothetical protein
CBO0941	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0941: hypothetical protein	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	hypothetical protein
CBO0941A	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0941A: membrane protein	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	membrane protein
CBO0942	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0942: membrane protein	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	membrane protein
CBO0943	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC01427: hypothetical protein	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0943: hypothetical protein	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_1895: hypothetical protein	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	hypothetical protein
CBO0944	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0944: Predicted secreted nucleic acid binding protein	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Predicted secreted nucleic acid binding protein
Cbei_3085	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC3465: Isochorismatase (EC 3.3.2.1)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0945: Isochorismatase (EC 3.3.2.1)	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630 Gene: CD3632: Isochorismatase (EC 3.3.2.1)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_3085: Isochorismatase (EC 3.3.2.1)	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_3090: Isochorismatase (EC 3.3.2.1)	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Isochorismatase (EC 3.3.2.1)
cbiL	Clostridium kluyveri DSM 555 Gene: CKL_0727: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1271: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Clostridium phytofermentans ISDg Gene: null: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Clostridium tetani E88 Gene: CTC00735: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Clostridium acetobutylicum ATCC 824 Gene: CAC1379: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0946: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Clostridium novyi NT Gene: NT01CX_0578: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Clostridium perfringens ATCC 13124 Gene: CPF_1431: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_2315: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Clostridium sp. OhILAs Gene: Clos_1023: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03592: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00709: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Clostridium butyricum 5521 Gene: CBY_3400: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_05125: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01408: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
cbiF	Clostridium kluyveri DSM 555 Gene: CKL_0728: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1272: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Clostridium phytofermentans ISDg Gene: null: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Clostridium tetani E88 Gene: CTC00736: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Clostridium acetobutylicum ATCC 824 Gene: CAC1380: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0947: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Clostridium novyi NT Gene: NT01CX_0577: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Clostridium perfringens ATCC 13124 Gene: CPF_1430: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Clostridium difficile 630 Gene: CD3426: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_2316: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Clostridium sp. OhILAs Gene: Clos_1019: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03593: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00704: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Clostridium butyricum 5521 Gene: CBY_3401: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01288: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01413: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
cbiG	Clostridium kluyveri DSM 555 Gene: CKL_0716: Cobalamin biosynthesis protein CbiG	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1273: Cobalamin biosynthesis protein CbiG	Clostridium phytofermentans ISDg Gene: null: Cobalamin biosynthesis protein CbiG	Clostridium tetani E88 Gene: CTC00737: Cobalamin biosynthesis protein CbiG	Clostridium acetobutylicum ATCC 824 Gene: CAC1370: Cobalamin biosynthesis protein CbiG	Clostridium botulinum A str. ATCC 3502 Gene: CBO0948: Cobalamin biosynthesis protein CbiG	Clostridium novyi NT Gene: NT01CX_0576: Cobalamin biosynthesis protein CbiG	Clostridium perfringens ATCC 13124 Gene: CPF_1429: Cobalamin biosynthesis protein CbiG	Clostridium difficile 630 Gene: CD3425: Cobalamin biosynthesis protein CbiG	Clostridium beijerincki NCIMB 8052 Gene: Cbei_2317: Cobalamin biosynthesis protein CbiG	Clostridium sp. OhILAs Gene: Clos_1020: Cobalamin biosynthesis protein CbiG	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03594: Cobalamin biosynthesis protein CbiG	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00705: Cobalamin biosynthesis protein CbiG	Clostridium butyricum 5521 Gene: CBY_3402: Cobalamin biosynthesis protein CbiG	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01290: Cobalamin biosynthesis protein CbiG	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01412: Cobalamin biosynthesis protein CbiG	Cobalamin biosynthesis protein CbiG
cbiH	Clostridium kluyveri DSM 555 Gene: CKL_0730: Cobalt-precorrin-3b C17-methyltransferase	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1275: Cobalt-precorrin-3b C17-methyltransferase	Clostridium phytofermentans ISDg Gene: null: Cobalt-precorrin-3b C17-methyltransferase	Clostridium tetani E88 Gene: CTC00739: Cobalt-precorrin-3b C17-methyltransferase	Clostridium acetobutylicum ATCC 824 Gene: CAC1382: Cobalt-precorrin-3b C17-methyltransferase	Clostridium botulinum A str. ATCC 3502 Gene: CBO0949: Cobalt-precorrin-3b C17-methyltransferase	Clostridium novyi NT Gene: NT01CX_0575: Cobalt-precorrin-3b C17-methyltransferase	Clostridium perfringens ATCC 13124 Gene: CPF_1428: Cobalt-precorrin-3b C17-methyltransferase	Clostridium difficile 630 Gene: CD3424: Cobalt-precorrin-3b C17-methyltransferase	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1257: Cobalt-precorrin-3b C17-methyltransferase	2 Clostridium sp. OhILAs Gene: Clos_1325: Cobalt-precorrin-3b C17-methyltransferase Gene: Clos_1021: Cobalt-precorrin-3b C17-methyltransferase	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03595: Cobalt-precorrin-3b C17-methyltransferase	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00706: Cobalt-precorrin-3b C17-methyltransferase	Clostridium butyricum 5521 Gene: CBY_3403: Cobalt-precorrin-3b C17-methyltransferase	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01411: Cobalt-precorrin-3b C17-methyltransferase	Cobalt-precorrin-3b C17-methyltransferase
cbiJ	Clostridium kluyveri DSM 555 Gene: CKL_0729: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1276: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	Clostridium phytofermentans ISDg Gene: null: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	Clostridium tetani E88 Gene: CTC00740: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	Clostridium acetobutylicum ATCC 824 Gene: CAC1381: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0950: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	Clostridium novyi NT Gene: NT01CX_0574: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	Clostridium perfringens ATCC 13124 Gene: CPF_1427: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	Clostridium difficile 630 Gene: CD3423: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1258: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	2 Clostridium sp. OhILAs Gene: Clos_1326: Cobalt-precorrin-6x reductase (EC 1.3.1.54) Gene: Clos_1022: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03596: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00707: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	Clostridium butyricum 5521 Gene: CBY_3404: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01287: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01410: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	Cobalt-precorrin-6x reductase (EC 1.3.1.54)
cblT	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC00741: Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0951: Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole	Clostridium novyi NT	* Clostridium perfringens ATCC 13124 Site: position = -544 score = 89.44 sequence = AAATAAAATAAGAGC... Gene: CPF_1515: Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_2207: Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole
cbiK	Clostridium kluyveri DSM 555 Gene: CKL_0720: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: null: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Clostridium tetani E88 Gene: CTC00743: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	2 Clostridium acetobutylicum ATCC 824 Gene: CAC1373: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) Gene: CAC0583: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0952: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Clostridium novyi NT Gene: NT01CX_0573: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	* Clostridium perfringens ATCC 13124 Site: position = -302 score = 115.43 sequence = ATAATATTTTATATT... Gene: CPF_1436: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Clostridium difficile 630	* Clostridium beijerincki NCIMB 8052 Site: position = -449 score = 79.31 sequence = ATAAGAAATGATTTT... Gene: Cbei_2309: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00708: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	* Clostridium butyricum 5521 Site: position = -357 score = 110.87 sequence = TAATAAATATGATTA... Gene: CBY_3393: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_05117: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01409: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
pduX	Clostridium kluyveri DSM 555 Gene: CKL_0717: Threonine kinase in B12 biosynthesis	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC00786: Threonine kinase in B12 biosynthesis	Clostridium acetobutylicum ATCC 824 Gene: CAC1371: Threonine kinase in B12 biosynthesis	Clostridium botulinum A str. ATCC 3502 Gene: CBO0953: Threonine kinase in B12 biosynthesis	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630 Gene: CD3431: Threonine kinase in B12 biosynthesis	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00699: Threonine kinase in B12 biosynthesis	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01418: Threonine kinase in B12 biosynthesis	Threonine kinase in B12 biosynthesis
btuR	Clostridium kluyveri DSM 555 Gene: CKL_0715: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	2 Clostridium phytofermentans ISDg Gene: null: Cob(I)alamin adenosyltransferase (EC 2.5.1.17) Gene: null: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	2 Clostridium tetani E88 Gene: CTC00744: Cob(I)alamin adenosyltransferase (EC 2.5.1.17) Gene: CTC00746: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0954: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Clostridium novyi NT Gene: NT01CX_0356: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1263: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_02251: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_1515: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_05368: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Clostridium bartlettii DSM 16795	Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
hemA	Clostridium kluyveri DSM 555 Gene: CKL_0657: Glutamyl-tRNA reductase (EC 1.2.1.70)	2 Clostridium sp. SS2/1 Gene: CLOSS21_01703: Glutamyl-tRNA reductase (EC 1.2.1.70) Gene: CLOSS21_00303: Glutamyl-tRNA reductase (EC 1.2.1.70)	Clostridium cellulolyticum H10 Gene: Ccel_1274: Glutamyl-tRNA reductase (EC 1.2.1.70)	2 Clostridium phytofermentans ISDg* Gene: null: Glutamyl-tRNA reductase (EC 1.2.1.70) Site: position = -362 score = 109.4 sequence = ACAATTTAGATCTTT... Gene: null: Glutamyl-tRNA reductase (EC 1.2.1.70)	Clostridium tetani E88 Gene: CTC00725: Glutamyl-tRNA reductase (EC 1.2.1.70)	Clostridium acetobutylicum ATCC 824 Gene: CAC0095: Glutamyl-tRNA reductase (EC 1.2.1.70)	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT Gene: NT01CX_0264: Glutamyl-tRNA reductase (EC 1.2.1.70)	Clostridium perfringens ATCC 13124 Gene: CPF_1690: Glutamyl-tRNA reductase (EC 1.2.1.70)	Clostridium difficile 630 Gene: CD2968: Glutamyl-tRNA reductase (EC 1.2.1.70)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1283: Glutamyl-tRNA reductase (EC 1.2.1.70)	Clostridium sp. OhILAs Gene: Clos_1324: Glutamyl-tRNA reductase (EC 1.2.1.70)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_3438: Glutamyl-tRNA reductase (EC 1.2.1.70)	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01428: Glutamyl-tRNA reductase (EC 1.2.1.70)	Glutamyl-tRNA reductase (EC 1.2.1.70)
hemL	Clostridium kluyveri DSM 555 Gene: CKL_0658: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)	Clostridium sp. SS2/1 Gene: CLOSS21_01704: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)	Clostridium cellulolyticum H10 Gene: Ccel_1280: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)	2 Clostridium phytofermentans ISDg Gene: null: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8) Gene: null: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)	Clostridium tetani E88 Gene: CTC00730: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)	Clostridium acetobutylicum ATCC 824 Gene: CAC0099: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT Gene: NT01CX_0259: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)	Clostridium perfringens ATCC 13124 Gene: CPF_1685: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1288: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)	Clostridium sp. OhILAs Gene: Clos_1330: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_3443: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01427: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)	Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)
cbiET	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1282: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC00734: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01286: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Clostridium bartlettii DSM 16795	Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
cblS	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC00742: Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO0822: Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis	Clostridium novyi NT	Clostridium perfringens ATCC 13124 Gene: CPF_1514: Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_2206: Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis
cbiO	Clostridium kluyveri DSM 555 Gene: CKL_3426: ATPase component CbiO of energizing module of cobalt ECF transporter	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1269: ATPase component CbiO of energizing module of cobalt ECF transporter	Clostridium phytofermentans ISDg Gene: null: ATPase component CbiO of energizing module of cobalt ECF transporter	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC1368: ATPase component CbiO of energizing module of cobalt ECF transporter	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT Gene: NT01CX_1332: ATPase component CbiO of energizing module of cobalt ECF transporter	Clostridium perfringens ATCC 13124 Gene: CPF_0188: ATPase component CbiO of energizing module of cobalt ECF transporter	Clostridium difficile 630 Gene: CD0327: ATPase component CbiO of energizing module of cobalt ECF transporter	Clostridium beijerincki NCIMB 8052 Gene: Cbei_3711: ATPase component CbiO of energizing module of cobalt ECF transporter	Clostridium sp. OhILAs Gene: Clos_1014: ATPase component CbiO of energizing module of cobalt ECF transporter	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03612: ATPase component CbiO of energizing module of cobalt ECF transporter	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01692: ATPase component CbiO of energizing module of cobalt ECF transporter	Clostridium butyricum 5521 Gene: CBY_1416: ATPase component CbiO of energizing module of cobalt ECF transporter	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01385: ATPase component CbiO of energizing module of cobalt ECF transporter	ATPase component CbiO of energizing module of cobalt ECF transporter
cbiX	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_1281: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
sstT	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1 Gene: CLOSS21_01676: hypothetical protein	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_01572: hypothetical protein	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	2 Clostridium bartlettii DSM 16795 Gene: CLOBAR_01404: hypothetical protein Gene: CLOBAR_01403: hypothetical protein	hypothetical protein
cysG3	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1 Gene: CLOSS21_01706: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)	Clostridium cellulolyticum H10	2 Clostridium phytofermentans ISDg Gene: null: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) Gene: null: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT Gene: NT01CX_0263: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)	Clostridium perfringens ATCC 13124	Clostridium difficile 630 Gene: CD3418: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03615: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00112: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_02877: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01402: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)	Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)
cobT	Clostridium kluyveri DSM 555 Gene: CKL_2908: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_0646: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	* Clostridium phytofermentans ISDg Site: position = -429 score = 95.93 sequence = AAAATATAATGTAGA... Gene: null: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	* Clostridium tetani E88 Site: position = -410 score = 111.09 sequence = AATTTAATATTAGAT... Gene: CTC02290: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Clostridium acetobutylicum ATCC 824 Gene: CAC1372: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Clostridium botulinum A str. ATCC 3502	* Clostridium novyi NT Site: position = -298 score = 106.96 sequence = AATTAAATAAGTCAT... Gene: NT01CX_2077: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Clostridium perfringens ATCC 13124 Gene: CPF_1289: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Clostridium difficile 630 Gene: CD3439: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1262: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03598: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_02222: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Clostridium butyricum 5521 Gene: CBY_0383: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01284: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01426: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
cobU	Clostridium kluyveri DSM 555 Gene: CKL_0731: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_0644: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Clostridium phytofermentans ISDg Gene: null: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Clostridium tetani E88 Gene: CTC00718: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Clostridium acetobutylicum ATCC 824 Gene: CAC1383: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0911: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Clostridium novyi NT Gene: NT01CX_2078: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Clostridium perfringens ATCC 13124 Gene: CPF_1290: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Clostridium difficile 630 Gene: CD3438: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1264: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Clostridium sp. OhILAs Gene: Clos_2210: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03599: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_02223: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Clostridium butyricum 5521 Gene: CBY_0384: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01283: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01425: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
cobS	Clostridium kluyveri DSM 555 Gene: CKL_3341: Cobalamin synthase	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_0645: Cobalamin synthase	Clostridium phytofermentans ISDg Gene: null: Cobalamin synthase	Clostridium tetani E88 Gene: CTC00719: Cobalamin synthase	Clostridium acetobutylicum ATCC 824 Gene: CAC1384: Cobalamin synthase	Clostridium botulinum A str. ATCC 3502 Gene: CBO0821: Cobalamin synthase	Clostridium novyi NT Gene: NT01CX_2079: Cobalamin synthase	Clostridium perfringens ATCC 13124 Gene: CPF_1291: Cobalamin synthase	Clostridium difficile 630 Gene: CD3437: Cobalamin synthase	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1265: Cobalamin synthase	Clostridium sp. OhILAs Gene: Clos_2209: Cobalamin synthase	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03600: Cobalamin synthase	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_02224: Cobalamin synthase	Clostridium butyricum 5521 Gene: CBY_0385: Cobalamin synthase	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01282: Cobalamin synthase	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01424: Cobalamin synthase	Cobalamin synthase
cobC	Clostridium kluyveri DSM 555 Gene: CKL_0732: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: null: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Clostridium tetani E88 Gene: CTC00717: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Clostridium acetobutylicum ATCC 824 Gene: CAC1385: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Clostridium botulinum A str. ATCC 3502 Gene: CBO0819: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Clostridium novyi NT Gene: NT01CX_2080: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Clostridium perfringens ATCC 13124 Gene: CPF_1293: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Clostridium difficile 630 Gene: CD3436: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1267: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Clostridium sp. OhILAs Gene: Clos_2208: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03602: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_02225: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Clostridium butyricum 5521 Gene: CBY_0387: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01423: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)	Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
cbiKL	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630 Gene: CD3422: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) / Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) / Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
CBY_3396	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_3396: hypothetical protein	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	hypothetical protein
Cbei_1273	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1273: hypothetical protein	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_3408: hypothetical protein	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	hypothetical protein
btuF	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	* Clostridium cellulolyticum H10 Site: position = -322 score = 78.95 sequence = TTTTATATTAATATA... Gene: Ccel_3204: Vitamin B12 ABC transporter, B12-binding component BtuF	* Clostridium phytofermentans ISDg Site: position = -401 score = 107.93 sequence = AATAATTGCGACCAT... Gene: null: Vitamin B12 ABC transporter, B12-binding component BtuF	2 Clostridium tetani E88* Gene: CTC00785: Vitamin B12 ABC transporter, B12-binding component BtuF Site: position = -301 score = 100.54 sequence = AATGTTTTATGAAAA... Gene: CTC00960: Vitamin B12 ABC transporter, B12-binding component BtuF	Clostridium acetobutylicum ATCC 824	2 Clostridium botulinum A str. ATCC 3502 Gene: CBO0301: Vitamin B12 ABC transporter, B12-binding component BtuF Gene: CBO1337: Vitamin B12 ABC transporter, B12-binding component BtuF	Clostridium novyi NT Gene: NT01CX_2084: Vitamin B12 ABC transporter, B12-binding component BtuF	2 Clostridium perfringens ATCC 13124* Gene: CPF_1426: Vitamin B12 ABC transporter, B12-binding component BtuF Site: position = -488 score = 84.15 sequence = TTGATTAACTAATAA... Gene: CPF_1296: Vitamin B12 ABC transporter, B12-binding component BtuF	Clostridium difficile 630	2 Clostridium beijerincki NCIMB 8052 Gene: Cbei_4504: Vitamin B12 ABC transporter, B12-binding component BtuF Gene: Cbei_3702: Vitamin B12 ABC transporter, B12-binding component BtuF	* Clostridium sp. OhILAs Site: position = -313 score = 116.3 sequence = ACGAATTCAATATAG... Gene: Clos_0915: Vitamin B12 ABC transporter, B12-binding component BtuF	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	2 Clostridium bartlettii DSM 16795 Gene: CLOBAR_00815: Vitamin B12 ABC transporter, B12-binding component BtuF Gene: CLOBAR_02761: Vitamin B12 ABC transporter, B12-binding component BtuF	Vitamin B12 ABC transporter, B12-binding component BtuF
btuC	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_3203: Vitamin B12 ABC transporter, permease component BtuC	Clostridium phytofermentans ISDg Gene: null: Vitamin B12 ABC transporter, permease component BtuC	2 Clostridium tetani E88 Gene: CTC00784: Vitamin B12 ABC transporter, permease component BtuC Gene: CTC00961: Vitamin B12 ABC transporter, permease component BtuC	Clostridium acetobutylicum ATCC 824	2 Clostridium botulinum A str. ATCC 3502 Gene: CBO0302: Vitamin B12 ABC transporter, permease component BtuC Gene: CBO1338: Vitamin B12 ABC transporter, permease component BtuC	Clostridium novyi NT Gene: NT01CX_2085: Vitamin B12 ABC transporter, permease component BtuC	2 Clostridium perfringens ATCC 13124 Gene: CPF_1425: Vitamin B12 ABC transporter, permease component BtuC Gene: CPF_1297: Vitamin B12 ABC transporter, permease component BtuC	Clostridium difficile 630	2 Clostridium beijerincki NCIMB 8052 Gene: Cbei_4502: Vitamin B12 ABC transporter, permease component BtuC Gene: Cbei_3703: Vitamin B12 ABC transporter, permease component BtuC	Clostridium sp. OhILAs Gene: Clos_0916: Vitamin B12 ABC transporter, permease component BtuC	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	2 Clostridium bartlettii DSM 16795 Gene: CLOBAR_00814: Vitamin B12 ABC transporter, permease component BtuC Gene: CLOBAR_02760: Vitamin B12 ABC transporter, permease component BtuC	Vitamin B12 ABC transporter, permease component BtuC
btuD	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10 Gene: Ccel_3202: Vitamin B12 ABC transporter, ATPase component BtuD	Clostridium phytofermentans ISDg Gene: null: Vitamin B12 ABC transporter, ATPase component BtuD	2 Clostridium tetani E88 Gene: CTC00783: Vitamin B12 ABC transporter, ATPase component BtuD Gene: CTC00962: Vitamin B12 ABC transporter, ATPase component BtuD	Clostridium acetobutylicum ATCC 824	2 Clostridium botulinum A str. ATCC 3502 Gene: CBO0303: Vitamin B12 ABC transporter, ATPase component BtuD Gene: CBO1339: Vitamin B12 ABC transporter, ATPase component BtuD	Clostridium novyi NT Gene: NT01CX_2086: Vitamin B12 ABC transporter, ATPase component BtuD	2 Clostridium perfringens ATCC 13124 Gene: CPF_1424: Vitamin B12 ABC transporter, ATPase component BtuD Gene: CPF_1298: Vitamin B12 ABC transporter, ATPase component BtuD	Clostridium difficile 630	2 Clostridium beijerincki NCIMB 8052 Gene: Cbei_4503: Vitamin B12 ABC transporter, ATPase component BtuD Gene: Cbei_3704: Vitamin B12 ABC transporter, ATPase component BtuD	Clostridium sp. OhILAs Gene: Clos_0917: Vitamin B12 ABC transporter, ATPase component BtuD	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	2 Clostridium bartlettii DSM 16795 Gene: CLOBAR_00813: Vitamin B12 ABC transporter, ATPase component BtuD Gene: CLOBAR_02759: Vitamin B12 ABC transporter, ATPase component BtuD	Vitamin B12 ABC transporter, ATPase component BtuD
cobU2	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: null: cobalamin biosynthesis protein CobU, putative, truncation	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124 Gene: CPF_1292: cobalamin biosynthesis protein CobU, putative, truncation	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1266: cobalamin biosynthesis protein CobU, putative, truncation	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704 Gene: CLOSCI_03601: cobalamin biosynthesis protein CobU, putative, truncation	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_0386: cobalamin biosynthesis protein CobU, putative, truncation	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_01281: cobalamin biosynthesis protein CobU, putative, truncation	Clostridium bartlettii DSM 16795	cobalamin biosynthesis protein CobU, putative, truncation
Fnod_1372	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124 Gene: CPF_1299: conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71	Clostridium difficile 630 Gene: CD1417: conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1271: conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00210: conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_02072: conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71	conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71
btuF1	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	* Clostridium tetani E88 Site: position = -324 score = 103.17 sequence = CATTTATAGAATAAA... Gene: CTC01372: Vitamin B12 ABC transporter, B12-binding component BtuF	* Clostridium acetobutylicum ATCC 824 Site: position = -338 score = 119.75 sequence = AATAATACCATATTT... Gene: CAC2441: Vitamin B12 ABC transporter, B12-binding component BtuF	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	* Clostridium difficile 630 Site: position = -401 score = 107.07 sequence = TAAATTAAAATAATA... Gene: CD2999: Vitamin B12 ABC transporter, B12-binding component BtuF	Clostridium beijerincki NCIMB 8052	* Clostridium sp. OhILAs Site: position = -340 score = 107.54 sequence = TGAATATCAAAGTAT... Gene: Clos_0948: Vitamin B12 ABC transporter, B12-binding component BtuF	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_05119: Vitamin B12 ABC transporter, B12-binding component BtuF	Clostridium bartlettii DSM 16795	Vitamin B12 ABC transporter, B12-binding component BtuF
btuC1	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC01371: Vitamin B12 ABC transporter, permease component BtuC	Clostridium acetobutylicum ATCC 824 Gene: CAC2442: Vitamin B12 ABC transporter, permease component BtuC	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630 Gene: CD2998: Vitamin B12 ABC transporter, permease component BtuC	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_0949: Vitamin B12 ABC transporter, permease component BtuC	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_05120: Vitamin B12 ABC transporter, permease component BtuC	Clostridium bartlettii DSM 16795	Vitamin B12 ABC transporter, permease component BtuC
btuD1	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC01370: Vitamin B12 ABC transporter, ATPase component BtuD	Clostridium acetobutylicum ATCC 824 Gene: CAC2443: Vitamin B12 ABC transporter, ATPase component BtuD	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630 Gene: CD2997: Vitamin B12 ABC transporter, ATPase component BtuD	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_0950: Vitamin B12 ABC transporter, ATPase component BtuD	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_05121: Vitamin B12 ABC transporter, ATPase component BtuD	Clostridium bartlettii DSM 16795	Vitamin B12 ABC transporter, ATPase component BtuD
crdX	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC2444: Cobalamine-related hypothetical metal-binding protein CrdX	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630 Gene: CD0787: Cobalamine-related hypothetical metal-binding protein CrdX	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_2205: Cobalamine-related hypothetical metal-binding protein CrdX	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01859: Cobalamine-related hypothetical metal-binding protein CrdX	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01221: Cobalamine-related hypothetical metal-binding protein CrdX	Cobalamine-related hypothetical metal-binding protein CrdX
CTC00745	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	* Clostridium tetani E88 Site: position = -277 score = 98.17 sequence = ATAATATGAATAAAA... Gene: CTC00745: ferredoxin-like protein	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	ferredoxin-like protein

CRON 7.
nikA	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_0431: nickel ABC transporter, periplasmic nickel-binding protein	* Clostridium bolteae ATCC BAA-613 Site: position = -325 score = 104.86 sequence = CGAACATAACCGTAT... Gene: CLOBOL_07302: nickel ABC transporter, periplasmic nickel-binding protein	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00449: nickel ABC transporter, periplasmic nickel-binding protein	nickel ABC transporter, periplasmic nickel-binding protein
nikB	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_0430: nickel ABC transporter, permease subunit NikB	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_07303: nickel ABC transporter, permease subunit NikB	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00450: nickel ABC transporter, permease subunit NikB	nickel ABC transporter, permease subunit NikB
nikC	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_0429: nickel ABC transporter, permease subunit NikC	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_07304: nickel ABC transporter, permease subunit NikC	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00451: nickel ABC transporter, permease subunit NikC	nickel ABC transporter, permease subunit NikC
dppD	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	2 Clostridium butyricum 5521 Gene: CBY_0428: oligopeptide transport ATP-binding protein OppD Gene: CBY_0427: oligopeptide transport ATP-binding protein OppD	2 Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_07305: oligopeptide transport ATP-binding protein OppD Gene: CLOBOL_07306: oligopeptide transport ATP-binding protein OppD	2 Clostridium bartlettii DSM 16795 Gene: CLOBAR_00452: oligopeptide transport ATP-binding protein OppD Gene: CLOBAR_00453: oligopeptide transport ATP-binding protein OppD	oligopeptide transport ATP-binding protein OppD
metE	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_07307: hypothetical protein	Clostridium bartlettii DSM 16795	hypothetical protein

CRON 8.
dppA	Clostridium kluyveri DSM 555 Gene: CKL_1049: Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	* Clostridium tetani E88 Site: position = -288 score = 100.81 sequence = TTAATATAATAAGAC... Gene: CTC01379: Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)
dppB	Clostridium kluyveri DSM 555 Gene: CKL_1050: Putative glutathione transporter, permease component	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC01378: Putative glutathione transporter, permease component	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Putative glutathione transporter, permease component
dppC	Clostridium kluyveri DSM 555 Gene: CKL_1051: Dipeptide transport system permease protein DppC (TC 3.A.1.5.2)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC01377: Dipeptide transport system permease protein DppC (TC 3.A.1.5.2)	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Dipeptide transport system permease protein DppC (TC 3.A.1.5.2)
dppD	2 Clostridium kluyveri DSM 555 Gene: CKL_1052: Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1) Gene: CKL_1053: Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1)	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	2 Clostridium tetani E88 Gene: CTC01376: Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1) Gene: CTC01375: Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1)	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1)

CRON 9.
CLOBAR_00570	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	* Clostridium bartlettii DSM 16795 Site: position = -320 score = 94.4 sequence = AAAAATAAGTAGTTA... Gene: CLOBAR_00570: hypothetical protein	hypothetical protein
dppB	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00569: hypothetical protein	hypothetical protein
dppC	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00568: hypothetical protein	hypothetical protein
dppA	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00567: hypothetical protein	hypothetical protein
dppD	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	2 Clostridium bartlettii DSM 16795 Gene: CLOBAR_00566: hypothetical protein Gene: CLOBAR_00565: hypothetical protein	hypothetical protein

CRON 10.
btuF	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	* Clostridium sp. OhILAs Site: position = -297 score = 48.69 sequence = ATAAAATATTTAAAA... Gene: Clos_2330: Vitamin B12 ABC transporter, B12-binding component BtuF	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Vitamin B12 ABC transporter, B12-binding component BtuF
btuC	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_2329: Vitamin B12 ABC transporter, permease component BtuC	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Vitamin B12 ABC transporter, permease component BtuC
cobN	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_2328: Cobalt chelatase CobN subunit	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Cobalt chelatase CobN subunit
chlI	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_2327: Cobalt chelatase ChiI subunit	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Cobalt chelatase ChiI subunit
chlD	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_2326: Cobalt chelatase ChiD subunit	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Cobalt chelatase ChiD subunit

CRON 11.
btuF	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: null: Vitamin B12 ABC transporter, B12-binding component BtuF	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	* Clostridium sp. OhILAs Site: position = -343 score = 125.97 sequence = AAATGAATACATTTT... Gene: Clos_0318: Vitamin B12 ABC transporter, B12-binding component BtuF	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753 Gene: CLOLEP_00034: Vitamin B12 ABC transporter, B12-binding component BtuF	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Vitamin B12 ABC transporter, B12-binding component BtuF
btuC	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: null: Vitamin B12 ABC transporter, permease component BtuC	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_0319: Vitamin B12 ABC transporter, permease component BtuC	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753 Gene: CLOLEP_00035: Vitamin B12 ABC transporter, permease component BtuC	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Vitamin B12 ABC transporter, permease component BtuC
btuD	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: null: Vitamin B12 ABC transporter, ATPase component BtuD	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_0320: Vitamin B12 ABC transporter, ATPase component BtuD	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753 Gene: CLOLEP_00036: Vitamin B12 ABC transporter, ATPase component BtuD	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Vitamin B12 ABC transporter, ATPase component BtuD
Clos_0321	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_0321: ABC transporter ATP-binding protein	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	ABC transporter ATP-binding protein
Clos_0322	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_0322: ABC transporter, permease protein	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	ABC transporter, permease protein
cbiK	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_0323: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) / Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) / Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)

CRON 12.
CLONEX_02595	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	* Clostridium nexile DSM 1787 Site: position = -393 score = 110.5 sequence = AGAGTGAAAATGTAT... Gene: CLONEX_02595: hypothetical protein	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	hypothetical protein
CLONEX_02596	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787 Gene: CLONEX_02596: hypothetical protein	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	hypothetical protein
CLOLEP_00713	Clostridium kluyveri DSM 555	* Clostridium sp. SS2/1 Site: position = -306 score = 91.3 sequence = GAAATGCATAATTTC... Gene: CLOSS21_00425: hypothetical protein	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_02121: hypothetical protein	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787 Gene: CLONEX_02597: hypothetical protein	Clostridium leptum DSM 753 Gene: CLOLEP_00713: hypothetical protein	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	hypothetical protein
cbrV	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1 Gene: CLOSS21_00426: Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC00751: Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_02122: Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787 Gene: CLONEX_02598: Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter	Clostridium leptum DSM 753 Gene: CLOLEP_00714: Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00416: Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter	Transmembrane component CbrV of energizing module of predicted cobalamin ECF transporter
cbrU	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1 Gene: CLOSS21_00427: Duplicated ATPase component CbrU of energizing module of predicted cobalamin ECF transporter	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	2 Clostridium tetani E88 Gene: CTC00752: Duplicated ATPase component CbrU of energizing module of predicted cobalamin ECF transporter Gene: CTC00753: Duplicated ATPase component CbrU of energizing module of predicted cobalamin ECF transporter	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_02123: Duplicated ATPase component CbrU of energizing module of predicted cobalamin ECF transporter	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787 Gene: CLONEX_02599: Duplicated ATPase component CbrU of energizing module of predicted cobalamin ECF transporter	Clostridium leptum DSM 753 Gene: CLOLEP_00715: Duplicated ATPase component CbrU of energizing module of predicted cobalamin ECF transporter	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00417: Duplicated ATPase component CbrU of energizing module of predicted cobalamin ECF transporter	Duplicated ATPase component CbrU of energizing module of predicted cobalamin ECF transporter
cbrT	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1 Gene: CLOSS21_00428: Substrate-specific component CbrT of predicted cobalamin ECF transporter	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC00754: Substrate-specific component CbrT of predicted cobalamin ECF transporter	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787 Gene: CLONEX_02600: Substrate-specific component CbrT of predicted cobalamin ECF transporter	Clostridium leptum DSM 753 Gene: CLOLEP_00716: Substrate-specific component CbrT of predicted cobalamin ECF transporter	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Substrate-specific component CbrT of predicted cobalamin ECF transporter
CLOLEP_00712	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	* Clostridium leptum DSM 753 Site: position = -293 score = 99.55 sequence = TCGGTCAATAGTCTT... Gene: CLOLEP_00712: hypothetical protein	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	hypothetical protein
btuR	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753 Gene: CLOLEP_00717: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
CLOSS21_00429	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1 Gene: CLOSS21_00429: hypothetical protein	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	hypothetical protein