Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Clostridium phytofermentans ISDg

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Clostridiaceae
Under regulation:
- Genes 32
- Operons 4
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -429
Score: 95.9
Sequence: AAAATATAATGTAGA...
Locus tag: null
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: null
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: null
Name: cobS
Funciton: Cobalamin synthase
Locus tag: null
Name: cobU2
Funciton: cobalamin biosynthesis protein CobU, putative, truncation
Locus tag: null
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: null
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: null
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: null
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: null
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
cobU
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
cobS
Cobalamin synthase
cobU2
cobalamin biosynthesis protein CobU, putative, truncation
cobC
Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
cbiB
Adenosylcobinamide-phosphate synthase
cobD
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
cbiP
Cobyric acid synthase
btuR
Cob(I)alamin adenosyltransferase (EC 2.5.1.17)

Position: -401
Score: 107.9
Sequence: AATAATTGCGACCAT...
Locus tag: null
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: null
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: null
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
btuC
Vitamin B12 ABC transporter, permease component BtuC
btuD
Vitamin B12 ABC transporter, ATPase component BtuD

Position: -371
Score: 50.2
Sequence: GAAGTTGGGTGCAAT...
Locus tag: null
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: null
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
Locus tag: null
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: null
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: null
Name: cbiK
Funciton: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
cbiQ
Transmembrane component CbiQ of energizing module of cobalt ECF transporter
cbiO
ATPase component CbiO of energizing module of cobalt ECF transporter
cbiM
Substrate-specific component CbiM of cobalt ECF transporter
cbiN
Additional substrate-specific component CbiN of cobalt ECF transporter
cbiK
Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)

Position: -362
Score: 109.4
Sequence: ACAATTTAGATCTTT...
Locus tag: null
Name: hemA
Funciton: Glutamyl-tRNA reductase (EC 1.2.1.70)
Locus tag: null
Name: cysG3
Funciton: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)
Locus tag: null
Name: hemC
Funciton: Porphobilinogen deaminase (EC 2.5.1.61)
Locus tag: null
Name: cobA-hemD
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
Locus tag: null
Name: hemB
Funciton: Porphobilinogen synthase (EC 4.2.1.24)
Locus tag: null
Name: hemL
Funciton: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)
Locus tag: null
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: null
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: null
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: null
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: null
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: null
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: null
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: null
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Locus tag: null
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
hemA
Glutamyl-tRNA reductase (EC 1.2.1.70)
cysG3
Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)
hemC
Porphobilinogen deaminase (EC 2.5.1.61)
cobA-hemD
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
hemB
Porphobilinogen synthase (EC 4.2.1.24)
hemL
Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)
cbiD
Cobalt-precorrin-6 synthase, anaerobic
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
cbiG
Cobalamin biosynthesis protein CbiG
cbiH
Cobalt-precorrin-3b C17-methyltransferase
cbiJ
Cobalt-precorrin-6x reductase (EC 1.3.1.54)
cbiA
Cobyrinic acid A,C-diamide synthase
btuR
Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD