Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Clostridium novyi NT

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Clostridiaceae
Under regulation:
- Genes 25
- Operons 3
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -298
Score: 107
Sequence: AATTAAATAAGTCAT...
Locus tag: NT01CX_2077
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: NT01CX_2078
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: NT01CX_2079
Name: cobS
Funciton: Cobalamin synthase
Locus tag: NT01CX_2080
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: NT01CX_2081
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: NT01CX_2082
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: NT01CX_2083
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: NT01CX_2084
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: NT01CX_2085
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: NT01CX_2086
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
cobU
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
cobS
Cobalamin synthase
cobC
Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
cbiP
Cobyric acid synthase
cbiB
Adenosylcobinamide-phosphate synthase
cobD
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
btuC
Vitamin B12 ABC transporter, permease component BtuC
btuD
Vitamin B12 ABC transporter, ATPase component BtuD

Position: -349
Score: 95.8
Sequence: AAAATACATACAAAG...
Locus tag: NT01CX_1329
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: NT01CX_1330
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: NT01CX_1331
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: NT01CX_1332
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
cbiM
Substrate-specific component CbiM of cobalt ECF transporter
cbiN
Additional substrate-specific component CbiN of cobalt ECF transporter
cbiQ
Transmembrane component CbiQ of energizing module of cobalt ECF transporter
cbiO
ATPase component CbiO of energizing module of cobalt ECF transporter

Position: -301
Score: 119.1
Sequence: AAAATTGTATATTAG...
Locus tag: NT01CX_0583
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: NT01CX_0582
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: NT01CX_0581
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: NT01CX_0580
Name: cbiE
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Locus tag: NT01CX_0579
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: NT01CX_0578
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: NT01CX_0577
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: NT01CX_0576
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: NT01CX_0575
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: NT01CX_0574
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: NT01CX_0573
Name: cbiK
Funciton: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
cbiA
Cobyrinic acid A,C-diamide synthase
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
cbiD
Cobalt-precorrin-6 synthase, anaerobic
cbiE
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
cbiT
Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
cbiG
Cobalamin biosynthesis protein CbiG
cbiH
Cobalt-precorrin-3b C17-methyltransferase
cbiJ
Cobalt-precorrin-6x reductase (EC 1.3.1.54)
cbiK
Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD