Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Clostridium botulinum A str. ATCC 3502

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Clostridiaceae
Under regulation:
- Genes 42
- Operons 1
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -323
Score: 122.7
Sequence: TTTAATAAAAAGATT...
Locus tag: CBO0914
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: CBO0915
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: CBO0916
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: CBO0917
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: CBO0917A
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: CBO0918
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: CBO0919
Name: cysG1
Funciton: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
Locus tag: CBO0920
Name: hemC
Funciton: Porphobilinogen deaminase (EC 2.5.1.61)
Locus tag: CBO0921
Name: cobA-hemD
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
Locus tag: CBO0922
Name: null
Funciton: hypothetical protein
Locus tag: CBO0923
Name: hemB
Funciton: Porphobilinogen synthase (EC 4.2.1.24)
Locus tag: CBO0924
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: CBO0925
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: CBO0926
Name: null
Funciton: CAAX amino terminal protease family
Locus tag: CBO0927
Name: wrbA
Funciton: Iron-sulfur flavoprotein
Locus tag: CBO0928
Name: Cbei_2684
Funciton: HD domain protein
Locus tag: CBO0929
Name: null
Funciton: hypothetical protein
Locus tag: CBO0930
Name: null
Funciton: Transcriptional regulator, MerR family
Locus tag: CBO0931
Name: CBO0931
Funciton: Acetyltransferase (EC 2.3.1.-)
Locus tag: CBO0933
Name: CD0837
Funciton: Nitroreductase family protein
Locus tag: CBO0934
Name: null
Funciton: membrane protein
Locus tag: CBO0935
Name: null
Funciton: Glutamate-rich protein grpB
Locus tag: CBO0936
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: CBO0937
Name: cbiE
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Locus tag: CBO0938
Name: CBO0938
Funciton: CAAX amino terminal protease family protein
Locus tag: CBO0939
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: CBO0940
Name: null
Funciton: hypothetical protein
Locus tag: CBO0941
Name: null
Funciton: hypothetical protein
Locus tag: CBO0941A
Name: null
Funciton: membrane protein
Locus tag: CBO0942
Name: null
Funciton: membrane protein
Locus tag: CBO0943
Name: null
Funciton: hypothetical protein
Locus tag: CBO0944
Name: null
Funciton: Predicted secreted nucleic acid binding protein
Locus tag: CBO0945
Name: Cbei_3085
Funciton: Isochorismatase (EC 3.3.2.1)
Locus tag: CBO0946
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: CBO0947
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: CBO0948
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: CBO0949
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: CBO0950
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: CBO0951
Name: cblT
Funciton: Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole
Locus tag: CBO0952
Name: cbiK
Funciton: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
Locus tag: CBO0953
Name: pduX
Funciton: Threonine kinase in B12 biosynthesis
Locus tag: CBO0954
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
CBO0914
cbiP
Cobyric acid synthase
CBO0915
cbiB
Adenosylcobinamide-phosphate synthase
CBO0916
cobD
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
CBO0917
cbiM
Substrate-specific component CbiM of cobalt ECF transporter
CBO0917A
cbiN
Additional substrate-specific component CbiN of cobalt ECF transporter
CBO0918
cbiQ
Transmembrane component CbiQ of energizing module of cobalt ECF transporter
CBO0919
cysG1
Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
CBO0920
hemC
Porphobilinogen deaminase (EC 2.5.1.61)
CBO0921
cobA-hemD
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
CBO0922
hypothetical protein
CBO0923
hemB
Porphobilinogen synthase (EC 4.2.1.24)
CBO0924
cbiA
Cobyrinic acid A,C-diamide synthase
CBO0925
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
CBO0926
CAAX amino terminal protease family
CBO0927
wrbA
Iron-sulfur flavoprotein
CBO0928
Cbei_2684
HD domain protein
CBO0929
hypothetical protein
CBO0930
Transcriptional regulator, MerR family
CBO0931
CBO0931
Acetyltransferase (EC 2.3.1.-)
CBO0933
CD0837
Nitroreductase family protein
CBO0934
membrane protein
CBO0935
Glutamate-rich protein grpB
CBO0936
cbiD
Cobalt-precorrin-6 synthase, anaerobic
CBO0937
cbiE
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
CBO0938
CBO0938
CAAX amino terminal protease family protein
CBO0939
cbiT
Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
CBO0940
hypothetical protein
CBO0941
hypothetical protein
CBO0941A
membrane protein
CBO0942
membrane protein
CBO0943
hypothetical protein
CBO0944
Predicted secreted nucleic acid binding protein
CBO0945
Cbei_3085
Isochorismatase (EC 3.3.2.1)
CBO0946
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
CBO0947
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
CBO0948
cbiG
Cobalamin biosynthesis protein CbiG
CBO0949
cbiH
Cobalt-precorrin-3b C17-methyltransferase
CBO0950
cbiJ
Cobalt-precorrin-6x reductase (EC 1.3.1.54)
CBO0951
cblT
Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole
CBO0952
cbiK
Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
CBO0953
pduX
Threonine kinase in B12 biosynthesis
CBO0954
btuR
Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
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