Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Clostridium cellulolyticum H10

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Clostridiaceae
Under regulation:
- Genes 25
- Operons 2
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -380
Score: 95.6
Sequence: TAATAATTAACGATA...
Locus tag: Ccel_1266
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: Ccel_1267
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: Ccel_1268
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: Ccel_1269
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
Locus tag: Ccel_1270
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: Ccel_1271
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: Ccel_1272
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: Ccel_1273
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: Ccel_1274
Name: hemA
Funciton: Glutamyl-tRNA reductase (EC 1.2.1.70)
Locus tag: Ccel_1275
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: Ccel_1276
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: Ccel_1277
Name: hemC
Funciton: Porphobilinogen deaminase (EC 2.5.1.61)
Locus tag: Ccel_1278
Name: cobA-hemD
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
Locus tag: Ccel_1279
Name: hemB
Funciton: Porphobilinogen synthase (EC 4.2.1.24)
Locus tag: Ccel_1280
Name: hemL
Funciton: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)
Locus tag: Ccel_1281
Name: cbiX
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Locus tag: Ccel_1282
Name: cbiET
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: Ccel_1283
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: Ccel_1284
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: Ccel_1285
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: Ccel_1286
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: Ccel_1287
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Ccel_1266
cbiM
Substrate-specific component CbiM of cobalt ECF transporter
Ccel_1267
cbiN
Additional substrate-specific component CbiN of cobalt ECF transporter
Ccel_1268
cbiQ
Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Ccel_1269
cbiO
ATPase component CbiO of energizing module of cobalt ECF transporter
Ccel_1270
cbiD
Cobalt-precorrin-6 synthase, anaerobic
Ccel_1271
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Ccel_1272
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Ccel_1273
cbiG
Cobalamin biosynthesis protein CbiG
Ccel_1274
hemA
Glutamyl-tRNA reductase (EC 1.2.1.70)
Ccel_1275
cbiH
Cobalt-precorrin-3b C17-methyltransferase
Ccel_1276
cbiJ
Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Ccel_1277
hemC
Porphobilinogen deaminase (EC 2.5.1.61)
Ccel_1278
cobA-hemD
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
Ccel_1279
hemB
Porphobilinogen synthase (EC 4.2.1.24)
Ccel_1280
hemL
Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)
Ccel_1281
cbiX
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Ccel_1282
cbiET
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Ccel_1283
cbiA
Cobyrinic acid A,C-diamide synthase
Ccel_1284
cbiP
Cobyric acid synthase
Ccel_1285
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Ccel_1286
cbiB
Adenosylcobinamide-phosphate synthase
Ccel_1287
cobD
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Position: -322
Score: 78.9
Sequence: TTTTATATTAATATA...
Locus tag: Ccel_3204
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: Ccel_3203
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: Ccel_3202
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
Ccel_3204
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
Ccel_3203
btuC
Vitamin B12 ABC transporter, permease component BtuC
Ccel_3202
btuD
Vitamin B12 ABC transporter, ATPase component BtuD
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