Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Clostridium bartlettii DSM 16795

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Clostridiaceae
Under regulation:
- Genes 36
- Operons 4
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -320
Score: 94.4
Sequence: AAAAATAAGTAGTTA...
Locus tag: CLOBAR_00570
Name: null
Funciton: hypothetical protein
Locus tag: CLOBAR_00569
Name: dppB
Funciton: hypothetical protein
Locus tag: CLOBAR_00568
Name: dppC
Funciton: hypothetical protein
Locus tag: CLOBAR_00567
Name: dppA
Funciton: hypothetical protein
Locus tag: CLOBAR_00566
Name: dppD
Funciton: hypothetical protein
Locus tag: CLOBAR_00565
Name: dppD
Funciton: hypothetical protein
CLOBAR_00570
hypothetical protein
CLOBAR_00569
dppB
hypothetical protein
CLOBAR_00568
dppC
hypothetical protein
CLOBAR_00567
dppA
hypothetical protein
CLOBAR_00566
dppD
hypothetical protein
CLOBAR_00565
dppD
hypothetical protein
Position: -386
Score: 114.7
Sequence: AGATGAAATGTATAT...
Locus tag: CLOBAR_01388
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: CLOBAR_01387
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: CLOBAR_01386
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: CLOBAR_01385
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
CLOBAR_01388
cbiM
Substrate-specific component CbiM of cobalt ECF transporter
CLOBAR_01387
cbiN
Additional substrate-specific component CbiN of cobalt ECF transporter
CLOBAR_01386
cbiQ
Transmembrane component CbiQ of energizing module of cobalt ECF transporter
CLOBAR_01385
cbiO
ATPase component CbiO of energizing module of cobalt ECF transporter
Position: -274
Score: 71.8
Sequence: AGGGAAAAAGGTACA...
Locus tag: CLOBAR_01422
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: CLOBAR_01421
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: CLOBAR_01420
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: CLOBAR_01419
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: CLOBAR_01418
Name: pduX
Funciton: Threonine kinase in B12 biosynthesis
Locus tag: CLOBAR_01417
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: CLOBAR_01416
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: CLOBAR_01415
Name: cbiE
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Locus tag: CLOBAR_01414
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: CLOBAR_01413
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: CLOBAR_01412
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: CLOBAR_01411
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: CLOBAR_01410
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: CLOBAR_01409
Name: cbiK
Funciton: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
Locus tag: CLOBAR_01408
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: CLOBAR_01407
Name: hemC
Funciton: Porphobilinogen deaminase (EC 2.5.1.61)
Locus tag: CLOBAR_01406
Name: cobA-hemD
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
Locus tag: CLOBAR_01405
Name: hemB
Funciton: Porphobilinogen synthase (EC 4.2.1.24)
Locus tag: CLOBAR_01404
Name: sstT
Funciton: hypothetical protein
Locus tag: CLOBAR_01403
Name: sstT
Funciton: hypothetical protein
Locus tag: CLOBAR_01402
Name: cysG3
Funciton: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)
CLOBAR_01422
cbiP
Cobyric acid synthase
CLOBAR_01421
cbiA
Cobyrinic acid A,C-diamide synthase
CLOBAR_01420
cbiB
Adenosylcobinamide-phosphate synthase
CLOBAR_01419
cobD
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
CLOBAR_01418
pduX
Threonine kinase in B12 biosynthesis
CLOBAR_01417
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
CLOBAR_01416
cbiD
Cobalt-precorrin-6 synthase, anaerobic
CLOBAR_01415
cbiE
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
CLOBAR_01414
cbiT
Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
CLOBAR_01413
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
CLOBAR_01412
cbiG
Cobalamin biosynthesis protein CbiG
CLOBAR_01411
cbiH
Cobalt-precorrin-3b C17-methyltransferase
CLOBAR_01410
cbiJ
Cobalt-precorrin-6x reductase (EC 1.3.1.54)
CLOBAR_01409
cbiK
Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
CLOBAR_01408
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
CLOBAR_01407
hemC
Porphobilinogen deaminase (EC 2.5.1.61)
CLOBAR_01406
cobA-hemD
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
CLOBAR_01405
hemB
Porphobilinogen synthase (EC 4.2.1.24)
CLOBAR_01404
sstT
hypothetical protein
CLOBAR_01403
sstT
hypothetical protein
CLOBAR_01402
cysG3
Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)
Position: -480
Score: 108.2
Sequence: TGAATTGAATATTGT...
Locus tag: CLOBAR_00841
Name: dppB
Funciton: inner membrane ABC transporter permease protein YddR
Locus tag: CLOBAR_00840
Name: dppC
Funciton: inner membrane ABC transporter permease protein YddQ
Locus tag: CLOBAR_00839
Name: dppA
Funciton: putative ABC-type dipeptide/nickel transport system, periplasmic component
Locus tag: CLOBAR_00838
Name: dppD
Funciton: oligopeptide transport ATP-binding protein AppD
Locus tag: CLOBAR_00837
Name: dppD
Funciton: oligopeptide transport ATP-binding protein AppD
CLOBAR_00841
dppB
inner membrane ABC transporter permease protein YddR
CLOBAR_00840
dppC
inner membrane ABC transporter permease protein YddQ
CLOBAR_00839
dppA
putative ABC-type dipeptide/nickel transport system, periplasmic component
CLOBAR_00838
dppD
oligopeptide transport ATP-binding protein AppD
CLOBAR_00837
dppD
oligopeptide transport ATP-binding protein AppD
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