Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Clostridium difficile 630

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Clostridiaceae
Under regulation:
- Genes 25
- Operons 3
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -373
Score: 102.8
Sequence: AAATATATAATATTA...
Locus tag: CD0324
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: CD0325
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: CD0326
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: CD0327
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
CD0324
cbiM
Substrate-specific component CbiM of cobalt ECF transporter
CD0325
cbiN
Additional substrate-specific component CbiN of cobalt ECF transporter
CD0326
cbiQ
Transmembrane component CbiQ of energizing module of cobalt ECF transporter
CD0327
cbiO
ATPase component CbiO of energizing module of cobalt ECF transporter
Position: -401
Score: 107.1
Sequence: TAAATTAAAATAATA...
Locus tag: CD2999
Name: btuF1
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: CD2998
Name: btuC1
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: CD2997
Name: btuD1
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
CD2999
btuF1
Vitamin B12 ABC transporter, B12-binding component BtuF
CD2998
btuC1
Vitamin B12 ABC transporter, permease component BtuC
CD2997
btuD1
Vitamin B12 ABC transporter, ATPase component BtuD
Position: -295
Score: 102.1
Sequence: GAATATTAGATTAAA...
Locus tag: CD3435
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: CD3434
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: CD3433
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: CD3432
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: CD3431
Name: pduX
Funciton: Threonine kinase in B12 biosynthesis
Locus tag: CD3430
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: CD3429
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: CD3428
Name: cbiE
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Locus tag: CD3427
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: CD3426
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: CD3425
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: CD3424
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: CD3423
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: CD3422
Name: cbiKL
Funciton: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) / Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: CD3421
Name: hemC
Funciton: Porphobilinogen deaminase (EC 2.5.1.61)
Locus tag: CD3420
Name: cobA-hemD
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
Locus tag: CD3419
Name: hemB
Funciton: Porphobilinogen synthase (EC 4.2.1.24)
Locus tag: CD3418
Name: cysG3
Funciton: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)
CD3435
cbiP
Cobyric acid synthase
CD3434
cbiA
Cobyrinic acid A,C-diamide synthase
CD3433
cbiB
Adenosylcobinamide-phosphate synthase
CD3432
cobD
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
CD3431
pduX
Threonine kinase in B12 biosynthesis
CD3430
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
CD3429
cbiD
Cobalt-precorrin-6 synthase, anaerobic
CD3428
cbiE
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
CD3427
cbiT
Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
CD3426
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
CD3425
cbiG
Cobalamin biosynthesis protein CbiG
CD3424
cbiH
Cobalt-precorrin-3b C17-methyltransferase
CD3423
cbiJ
Cobalt-precorrin-6x reductase (EC 1.3.1.54)
CD3422
cbiKL
Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) / Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
CD3421
hemC
Porphobilinogen deaminase (EC 2.5.1.61)
CD3420
cobA-hemD
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
CD3419
hemB
Porphobilinogen synthase (EC 4.2.1.24)
CD3418
cysG3
Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76)
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