Regulon of Cobalamin in Clostridium tetani E88

Properties
Regulator type:	RNA regulatory element
Name:	Cobalamin
RFAM:	RF00174
Regulation mode:
Biological process:	Cobalamin biosynthesis
Effector:	Adenosylcobalamin
Regulog:	Cobalamin - Clostridiaceae
Under regulation:
- Genes	45
- Operons	8

Member of regulog collections

By taxonomy - Clostridiaceae
By RNA motif - Cobalamin
By effector - Adenosylcobalamin
By pathway - Cobalamin biosynthesis

Regulated operons
	Locus Tag	Name	Function
Position: -405 Score: 115.7 Sequence: TAAATATTTATTTAT... Locus tag: CTC00778 Name: null Funciton: hypothetical protein
	CTC00778		hypothetical protein
Position: -305 Score: 121.7 Sequence: ATATTATGAATTTTT... Locus tag: CTC01400 Name: dppA Funciton: periplasmic dipeptide transport protein precursor Locus tag: CTC01401 Name: dppB Funciton: transport system permease, nickel or dipeptide Locus tag: CTC01402 Name: dppC Funciton: transport system permease, dipeptide or nickel Locus tag: CTC01403 Name: dppD Funciton: Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1) Locus tag: CTC01404 Name: dppF Funciton: peptide transport ATP-binding protein Locus tag: CTC01405 Name: null Funciton: Methyltransferase (EC 2.1.1.-)
	CTC01400	dppA	periplasmic dipeptide transport protein precursor
	CTC01401	dppB	transport system permease, nickel or dipeptide
	CTC01402	dppC	transport system permease, dipeptide or nickel
	CTC01403	dppD	Oligopeptide transport system permease protein OppB (TC 3.A.1.5.1)
	CTC01404	dppF	peptide transport ATP-binding protein
	CTC01405		Methyltransferase (EC 2.1.1.-)
Position: -301 Score: 100.5 Sequence: AATGTTTTATGAAAA... Locus tag: CTC00960 Name: btuF Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF Locus tag: CTC00961 Name: btuC Funciton: Vitamin B12 ABC transporter, permease component BtuC Locus tag: CTC00962 Name: btuD Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
	CTC00960	btuF	Vitamin B12 ABC transporter, B12-binding component BtuF
	CTC00961	btuC	Vitamin B12 ABC transporter, permease component BtuC
	CTC00962	btuD	Vitamin B12 ABC transporter, ATPase component BtuD
Position: -324 Score: 103.2 Sequence: CATTTATAGAATAAA... Locus tag: CTC01372 Name: btuF1 Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF Locus tag: CTC01371 Name: btuC1 Funciton: Vitamin B12 ABC transporter, permease component BtuC Locus tag: CTC01370 Name: btuD1 Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
	CTC01372	btuF1	Vitamin B12 ABC transporter, B12-binding component BtuF
	CTC01371	btuC1	Vitamin B12 ABC transporter, permease component BtuC
	CTC01370	btuD1	Vitamin B12 ABC transporter, ATPase component BtuD
Position: -410 Score: 111.1 Sequence: AATTTAATATTAGAT... Locus tag: CTC02290 Name: cobT Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
	CTC02290	cobT	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Position: -277 Score: 98.2 Sequence: ATAATATGAATAAAA... Locus tag: CTC00745 Name: null Funciton: ferredoxin-like protein Locus tag: CTC00746 Name: btuR Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
	CTC00745		ferredoxin-like protein
	CTC00746	btuR	Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Position: -400 Score: 126.4 Sequence: GAATATGAAAATATT... Locus tag: CTC00720 Name: cbiP Funciton: Cobyric acid synthase Locus tag: CTC00721 Name: cbiB Funciton: Adenosylcobinamide-phosphate synthase Locus tag: CTC00722 Name: cobD Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) Locus tag: CTC00723 Name: cbiM Funciton: Substrate-specific component CbiM of cobalt ECF transporter Locus tag: CTC00724 Name: cbiQ Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter Locus tag: CTC00725 Name: hemA Funciton: Glutamyl-tRNA reductase (EC 1.2.1.70) Locus tag: CTC00726 Name: cysG1 Funciton: Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) Locus tag: CTC00727 Name: hemC Funciton: Porphobilinogen deaminase (EC 2.5.1.61) Locus tag: CTC00728 Name: cobA-hemD Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75) Locus tag: CTC00729 Name: hemB Funciton: Porphobilinogen synthase (EC 4.2.1.24) Locus tag: CTC00730 Name: hemL Funciton: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8) Locus tag: CTC00731 Name: cbiA Funciton: Cobyrinic acid A,C-diamide synthase Locus tag: CTC00732 Name: cbiC Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) Locus tag: CTC00733 Name: cbiD Funciton: Cobalt-precorrin-6 synthase, anaerobic Locus tag: CTC00734 Name: cbiET Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) Locus tag: CTC00735 Name: cbiL Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) Locus tag: CTC00736 Name: cbiF Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) Locus tag: CTC00737 Name: cbiG Funciton: Cobalamin biosynthesis protein CbiG Locus tag: CTC00739 Name: cbiH Funciton: Cobalt-precorrin-3b C17-methyltransferase Locus tag: CTC00740 Name: cbiJ Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54) Locus tag: CTC00741 Name: cblT Funciton: Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole Locus tag: CTC00742 Name: cblS Funciton: Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis Locus tag: CTC00743 Name: cbiK Funciton: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) Locus tag: CTC00744 Name: btuR Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
	CTC00720	cbiP	Cobyric acid synthase
	CTC00721	cbiB	Adenosylcobinamide-phosphate synthase
	CTC00722	cobD	L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
	CTC00723	cbiM	Substrate-specific component CbiM of cobalt ECF transporter
	CTC00724	cbiQ	Transmembrane component CbiQ of energizing module of cobalt ECF transporter
	CTC00725	hemA	Glutamyl-tRNA reductase (EC 1.2.1.70)
	CTC00726	cysG1	Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
	CTC00727	hemC	Porphobilinogen deaminase (EC 2.5.1.61)
	CTC00728	cobA-hemD	Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
	CTC00729	hemB	Porphobilinogen synthase (EC 4.2.1.24)
	CTC00730	hemL	Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)
	CTC00731	cbiA	Cobyrinic acid A,C-diamide synthase
	CTC00732	cbiC	Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
	CTC00733	cbiD	Cobalt-precorrin-6 synthase, anaerobic
	CTC00734	cbiET	Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
	CTC00735	cbiL	Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
	CTC00736	cbiF	Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
	CTC00737	cbiG	Cobalamin biosynthesis protein CbiG
	CTC00739	cbiH	Cobalt-precorrin-3b C17-methyltransferase
	CTC00740	cbiJ	Cobalt-precorrin-6x reductase (EC 1.3.1.54)
	CTC00741	cblT	Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole
	CTC00742	cblS	Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis
	CTC00743	cbiK	Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
	CTC00744	btuR	Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Position: -288 Score: 100.8 Sequence: TTAATATAATAAGAC... Locus tag: CTC01379 Name: dppA Funciton: Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1) Locus tag: CTC01378 Name: dppB Funciton: Putative glutathione transporter, permease component Locus tag: CTC01377 Name: dppC Funciton: Dipeptide transport system permease protein DppC (TC 3.A.1.5.2) Locus tag: CTC01376 Name: dppD Funciton: Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1) Locus tag: CTC01375 Name: dppD Funciton: Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1)
	CTC01379	dppA	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1)
	CTC01378	dppB	Putative glutathione transporter, permease component
	CTC01377	dppC	Dipeptide transport system permease protein DppC (TC 3.A.1.5.2)
	CTC01376	dppD	Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1)
	CTC01375	dppD	Oligopeptide transport ATP-binding protein OppD (TC 3.A.1.5.1)

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of Cobalamin in Clostridium tetani E88

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --