Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Clostridium perfringens ATCC 13124

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Clostridiaceae
Under regulation:
- Genes 24
- Operons 4
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -544
Score: 89.4
Sequence: AAATAAAATAAGAGC...
Locus tag: CPF_1515
Name: cblT
Funciton: Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole
Locus tag: CPF_1514
Name: cblS
Funciton: Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis
cblT
Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole
cblS
Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis

Position: -488
Score: 84.2
Sequence: TTGATTAACTAATAA...
Locus tag: CPF_1296
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: CPF_1297
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: CPF_1298
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
Locus tag: CPF_1299
Name: Fnod_1372
Funciton: conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71
Locus tag: CPF_1300
Name: cbiP
Funciton: Cobyric acid synthase
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
btuC
Vitamin B12 ABC transporter, permease component BtuC
btuD
Vitamin B12 ABC transporter, ATPase component BtuD
Fnod_1372
conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71
cbiP
Cobyric acid synthase

Position: -486
Score: 93.5
Sequence: TTAAATATTTAGAAA...
Locus tag: CPF_0185
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: CPF_0186
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: CPF_0187
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: CPF_0188
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
cbiM
Substrate-specific component CbiM of cobalt ECF transporter
cbiN
Additional substrate-specific component CbiN of cobalt ECF transporter
cbiQ
Transmembrane component CbiQ of energizing module of cobalt ECF transporter
cbiO
ATPase component CbiO of energizing module of cobalt ECF transporter

Position: -302
Score: 115.4
Sequence: ATAATATTTTATATT...
Locus tag: CPF_1436
Name: cbiK
Funciton: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
Locus tag: CPF_1435
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: CPF_1434
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: CPF_1433
Name: cbiE
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
Locus tag: CPF_1432
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: CPF_1431
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: CPF_1430
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: CPF_1429
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: CPF_1428
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: CPF_1427
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: CPF_1426
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: CPF_1425
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: CPF_1424
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
cbiK
Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
cbiD
Cobalt-precorrin-6 synthase, anaerobic
cbiE
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
cbiT
Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
cbiG
Cobalamin biosynthesis protein CbiG
cbiH
Cobalt-precorrin-3b C17-methyltransferase
cbiJ
Cobalt-precorrin-6x reductase (EC 1.3.1.54)
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
btuC
Vitamin B12 ABC transporter, permease component BtuC
btuD
Vitamin B12 ABC transporter, ATPase component BtuD
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