Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing cobC gene

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Phylum: Firmicutes
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Clostridium acetobutylicum ATCC 824
Position: -313
Score: 105.44
Sequence: TGCTACTAAAATTTG...
Locus tag: CAC1365
Name: cbiM
Funciton: Substrate-specific component CbiM of cobalt ECF transporter
Locus tag: CAC1366
Name: cbiN
Funciton: Additional substrate-specific component CbiN of cobalt ECF transporter
Locus tag: CAC1367
Name: cbiQ
Funciton: Transmembrane component CbiQ of energizing module of cobalt ECF transporter
Locus tag: CAC1368
Name: cbiO
Funciton: ATPase component CbiO of energizing module of cobalt ECF transporter
Locus tag: CAC1369
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: CAC1370
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: CAC1371
Name: pduX
Funciton: Threonine kinase in B12 biosynthesis
Locus tag: CAC1372
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: CAC1373
Name: cbiK
Funciton: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
Locus tag: CAC1374
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: CAC1375
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: CAC1376
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: CAC1377
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: CAC1378
Name: cbiT
Funciton: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: CAC1379
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: CAC1380
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: CAC1381
Name: cbiJ
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54)
Locus tag: CAC1382
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: CAC1383
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: CAC1384
Name: cobS
Funciton: Cobalamin synthase
Locus tag: CAC1385
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
cbiM-cbiN-cbiQ-cbiO-cobD-cbiG-pduX-cobT-cbiK-cbiP-cbiA-cbiC-cbiD-cbiT-cbiL-cbiF-cbiJ-cbiH-cobU-cobS-cobC -313 105.4 TGCTACTAAAATTTG... CAC1365
Clostridium novyi NT
Position: -298
Score: 106.96
Sequence: AATTAAATAAGTCAT...
Locus tag: NT01CX_2077
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: NT01CX_2078
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: NT01CX_2079
Name: cobS
Funciton: Cobalamin synthase
Locus tag: NT01CX_2080
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: NT01CX_2081
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: NT01CX_2082
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: NT01CX_2083
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: NT01CX_2084
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: NT01CX_2085
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: NT01CX_2086
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
cobT-cobU-cobS-cobC-cbiP-cbiB-cobD-btuF-btuC-btuD -298 107 AATTAAATAAGTCAT... NT01CX_2077
Clostridium phytofermentans ISDg
Position: -429
Score: 95.93
Sequence: AAAATATAATGTAGA...
Locus tag: null
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Locus tag: null
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: null
Name: cobS
Funciton: Cobalamin synthase
Locus tag: null
Name: cobU2
Funciton: cobalamin biosynthesis protein CobU, putative, truncation
Locus tag: null
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: null
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: null
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: null
Name: cbiP
Funciton: Cobyric acid synthase
Locus tag: null
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
cobT-cobU-cobS-cobU2-cobC-cbiB-cobD-cbiP-btuR -429 95.9 AAAATATAATGTAGA... null
Clostridium sp. OhILAs
Position: -319
Score: 118.45
Sequence: ACAAATTAAATAGTT...
Locus tag: Clos_2212
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: Clos_2211
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: Clos_2210
Name: cobU
Funciton: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Locus tag: Clos_2209
Name: cobS
Funciton: Cobalamin synthase
Locus tag: Clos_2208
Name: cobC
Funciton: Alpha-ribazole-5'-phosphate phosphatase (EC 3.1.3.73)
Locus tag: Clos_2207
Name: cblT
Funciton: Substrate-specific component CblT of predicted B12-regulated ECF transporter for dimethylbenzimidazole
Locus tag: Clos_2206
Name: cblS
Funciton: Predicted alpha-ribazole-5-phosphate synthase CblS for cobalamin biosynthesis
cbiB-cobD-cobU-cobS-cobC-cblT-cblS -319 118.4 ACAAATTAAATAGTT... Clos_2212