Regulog Zur - Lactobacillaceae

Properties
Regulator type:	Transcription factor
Regulator family:	FUR
Regulation mode:	repressor
Biological process:	Zinc homeostasis
Effector:	Zinc ion, (Zn2+)
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 43 sites [see more]

Member of regulog collections

By taxonomy - Lactobacillaceae
By trascription factor - Zur
By TF family - FUR
By effector - Zinc ion, (Zn2+)
By pathway - Zinc homeostasis

Statistics of regulated genes
Genome	Genes	Operons
Lactobacillus acidophilus NCFM
Lactobacillus brevis ATCC 367	5	3
Lactobacillus casei ATCC 334	6	5
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
Lactobacillus fermentum IFO 3956	5	3
Lactobacillus helveticus DPC 4571
Lactobacillus johnsonii NCC 533
Lactobacillus plantarum WCFS1	7	6
Lactobacillus reuteri JCM 1112	3	2
Lactobacillus rhamnosus GG	5	4
Lactobacillus sakei subsp. sakei 23K	3	1
Lactobacillus salivarius subsp. salivarius UCC118	6	3
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	4	2
Oenococcus oeni PSU-1	4	3
Pediococcus pentosaceus ATCC 25745	4	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																Function

CRON 1.
zur	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367 Gene: LVIS_1778: Zinc homeostasis transcriptional regulator Zur, Fur family	* Lactobacillus casei ATCC 334 Site: position = -69 score = 6.48354 sequence = TTAATCGTAATCAATACGATTTA Gene: LSEI_2025: Zinc homeostasis transcriptional regulator Zur, Fur family	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	* Lactobacillus fermentum IFO 3956 Site: position = -37 score = 5.82657 sequence = AAAAACGTAATCATTACTAAAAA Gene: LAF_1665: Zinc homeostasis transcriptional regulator Zur, Fur family	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	* Lactobacillus plantarum WCFS1 Site: position = -56 score = 6.89101 sequence = TAAATAGTAATGATTATGATTTA Gene: lp_0868: Zinc homeostasis transcriptional regulator Zur, Fur family	Lactobacillus reuteri JCM 1112 Gene: LAR_1528: Zinc homeostasis transcriptional regulator Zur, Fur family	* Lactobacillus rhamnosus GG Site: position = -70 score = 5.3752 sequence = CTAATCGTAACCAGTACGATTTG Gene: LGG_02012: Zinc homeostasis transcriptional regulator Zur, Fur family	Lactobacillus sakei subsp. sakei 23K Gene: LSA0109: Zinc homeostasis transcriptional regulator Zur, Fur family	* Lactobacillus salivarius subsp. salivarius UCC118 Site: position = -35 score = 6.56728 sequence = TAGAAAGTAAAGATTACTATTTA Gene: LSL_1450: Zinc homeostasis transcriptional regulator Zur, Fur family	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0802: Zinc homeostasis transcriptional regulator Zur, Fur family	* Oenococcus oeni PSU-1 Site: position = -95 score = 5.39986 sequence = TTAATGGTAAATATTACTTTTAC Site: position = -53 score = 6.00086 sequence = TACTTAGTAATGATTACTTGTTA Gene: OEOE_1189: Zinc homeostasis transcriptional regulator Zur, Fur family	* Pediococcus pentosaceus ATCC 25745 Site: position = -36 score = 7.28434 sequence = TAAAACGTAATGATTACTATTTA Gene: PEPE_0386: Zinc homeostasis transcriptional regulator Zur, Fur family	Zinc homeostasis transcriptional regulator Zur, Fur family

CRON 2.
znuA	Lactobacillus acidophilus NCFM	2 Lactobacillus brevis ATCC 367* Site: position = -46 score = 6.55558 sequence = TAAACGGTAATCATTACTGTTTA Gene: LVIS_0470: Zinc ABC transporter, substrate-binding protein Site: position = -41 score = 6.84989 sequence = TAAATAGTAATAATTACCATTTA Gene: LVIS_0566: Zinc ABC transporter, substrate-binding protein	* Lactobacillus casei ATCC 334 Site: position = -183 score = 6.96151 sequence = TAATTCGTAATCATTACTATTTA Site: position = -40 score = 6.72859 sequence = TAAATCGTAATTATTACGTTTTG Gene: LSEI_2427: Zinc ABC transporter, substrate-binding protein	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	* Lactobacillus fermentum IFO 3956 Site: position = -48 score = 6.7073 sequence = TTAATCGTAAGGATTACGATTTA Gene: LAF_0191: Zinc ABC transporter, substrate-binding protein	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	2 Lactobacillus plantarum WCFS1* Site: position = -44 score = 6.63799 sequence = TTAACAGTAATGGTTACGATTTA Gene: lp_3302: Zinc ABC transporter, substrate-binding protein Site: position = -88 score = 6.81674 sequence = TAAAACGTAAATATTACTATTTA Site: position = -39 score = 7.28434 sequence = TAAAACGTAATGATTACTATTTA Gene: lp_3018: Zinc ABC transporter, substrate-binding protein	* Lactobacillus reuteri JCM 1112 Site: position = -36 score = 6.75528 sequence = TAAATAGTAACGATTACGATTAA Gene: LAR_0207: Zinc ABC transporter, substrate-binding protein	* Lactobacillus rhamnosus GG Site: position = -181 score = 6.73087 sequence = TAAATCGTAATCATTACGCTTAA Site: position = -40 score = 6.87575 sequence = TAAATCGTAATGATTACGTTTTG Gene: LGG_02423: Zinc ABC transporter, substrate-binding protein	* Lactobacillus sakei subsp. sakei 23K Site: position = -37 score = 6.51111 sequence = TAAAGCGTAACTATTACGATTTA Gene: LSA0282: Zinc ABC transporter, substrate-binding protein	* Lactobacillus salivarius subsp. salivarius UCC118 Site: position = -40 score = 6.96151 sequence = TAAAAAGTAATGATTACTATATA Gene: LSL_1587: Zinc ABC transporter, substrate-binding protein	2 Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293* Site: position = -171 score = 6.21331 sequence = TTTAAAGTAATCATTACTTTTTG Site: position = -142 score = 6.18857 sequence = TTAATAGTAATGATTACTATAAT Gene: LEUM_0803: Zinc ABC transporter, substrate-binding protein Gene: LEUM_1611: Zinc ABC transporter, substrate-binding protein	* Oenococcus oeni PSU-1 Site: position = -76 score = 5.5295 sequence = GTAAAAGTAATATTTACCATTAA Site: position = -118 score = 6.01278 sequence = TAACAAGTAATCATTACTAAGTA Gene: OEOE_1188: Zinc ABC transporter, substrate-binding protein	* Pediococcus pentosaceus ATCC 25745 Site: position = -33 score = 6.92786 sequence = TAAATAGTAATTATTACTCTTTA Gene: PEPE_0289: Zinc ABC transporter, substrate-binding protein	Zinc ABC transporter, substrate-binding protein
znuC	Lactobacillus acidophilus NCFM Gene: LBA1772: Zinc ABC transporter, ATP-binding protein	Lactobacillus brevis ATCC 367 Gene: LVIS_0471: Zinc ABC transporter, ATP-binding protein	* Lactobacillus casei ATCC 334 Site: position = -39 score = 6.38872 sequence = TAAACCGTAATCGTTACCGTTTA Gene: LSEI_0242: Zinc ABC transporter, ATP-binding protein	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_1884: Zinc ABC transporter, ATP-binding protein	Lactobacillus fermentum IFO 3956 Gene: LAF_0192: Zinc ABC transporter, ATP-binding protein	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533 Gene: LJ0578: Zinc ABC transporter, ATP-binding protein	* Lactobacillus plantarum WCFS1 Site: position = -51 score = 6.85012 sequence = AAAATAGTAATCATTACGATTTA Gene: lp_0463: Zinc ABC transporter, ATP-binding protein	Lactobacillus reuteri JCM 1112 Gene: LAR_0208: Zinc ABC transporter, ATP-binding protein	* Lactobacillus rhamnosus GG Site: position = -39 score = 6.35616 sequence = TAAATCGTAATCGTTACCGTTTG Gene: LGG_00285: Zinc ABC transporter, ATP-binding protein	Lactobacillus sakei subsp. sakei 23K Gene: LSA0283: Zinc ABC transporter, ATP-binding protein	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_1586: Zinc ABC transporter, ATP-binding protein	2 Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0804: Zinc ABC transporter, ATP-binding protein Gene: LEUM_1610: Zinc ABC transporter, ATP-binding protein	Oenococcus oeni PSU-1 Gene: OEOE_1187: Zinc ABC transporter, ATP-binding protein	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0290: Zinc ABC transporter, ATP-binding protein	Zinc ABC transporter, ATP-binding protein
znuB	Lactobacillus acidophilus NCFM Gene: LBA1771: Zinc ABC transporter, permease protein	Lactobacillus brevis ATCC 367 Gene: LVIS_0472: Zinc ABC transporter, permease protein	Lactobacillus casei ATCC 334 Gene: LSEI_0243: Zinc ABC transporter, permease protein	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_1883: Zinc ABC transporter, permease protein	Lactobacillus fermentum IFO 3956 Gene: LAF_0193: Zinc ABC transporter, permease protein	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533 Gene: LJ0579: Zinc ABC transporter, permease protein	Lactobacillus plantarum WCFS1 Gene: lp_0464: Zinc ABC transporter, permease protein	* Lactobacillus reuteri JCM 1112 Site: position = -9 score = 5.32352 sequence = TAAAAAGTAATGTTAACTTTAAG Gene: LAR_0209: Zinc ABC transporter, permease protein	Lactobacillus rhamnosus GG Gene: LGG_00286: Zinc ABC transporter, permease protein	Lactobacillus sakei subsp. sakei 23K Gene: LSA0284: Zinc ABC transporter, permease protein	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_1585: Zinc ABC transporter, permease protein	2 Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1609: Zinc ABC transporter, permease protein Gene: LEUM_0805: Zinc ABC transporter, permease protein	Oenococcus oeni PSU-1	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0291: Zinc ABC transporter, permease protein	Zinc ABC transporter, permease protein

CRON 3.
rpsN2	Lactobacillus acidophilus NCFM	* Lactobacillus brevis ATCC 367 Site: position = -37 score = 5.92368 sequence = TAAAGCGTAATAATTACTATCAA Gene: LVIS_0360: Small subunit ribosomal protein S14, zinc-independent	2 Lactobacillus casei ATCC 334* Site: position = -248 score = 6.89799 sequence = TAAATAGTAATGATTACGAATTA Gene: LSEI_2425: Small subunit ribosomal protein S14, zinc-independent Gene: LSEI_0910: Small subunit ribosomal protein S14, zinc-independent	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	* Lactobacillus fermentum IFO 3956 Site: position = -82 score = 6.49412 sequence = TAAATGGTAATAATTACTATTTG Gene: LAF_1127: Small subunit ribosomal protein S14, zinc-independent	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533 Gene: LJ0166: Small subunit ribosomal protein S14, zinc-independent	* Lactobacillus plantarum WCFS1 Site: position = -125 score = 5.58235 sequence = AAAATAGTAGCTGTTACGATTTA Gene: lp_2216: Small subunit ribosomal protein S14, zinc-independent	Lactobacillus reuteri JCM 1112 Gene: LAR_1024: Small subunit ribosomal protein S14, zinc-independent	2 Lactobacillus rhamnosus GG* Site: position = -243 score = 6.77833 sequence = TTAAGCGTAATGATTACGATTTA Gene: LGG_02422: Small subunit ribosomal protein S14, zinc-independent Gene: LGG_00873: Small subunit ribosomal protein S14, zinc-independent	Lactobacillus sakei subsp. sakei 23K Gene: LSA0266: Small subunit ribosomal protein S14, zinc-independent	* Lactobacillus salivarius subsp. salivarius UCC118 Site: position = -42 score = 7.2976 sequence = TAAAAAGTAATGATTACTATTTA Site: position = -63 score = 5.72721 sequence = TAAATCGTAATTGATATCATTTA Gene: LSL_1944: Small subunit ribosomal protein S14, zinc-independent	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1360: Small subunit ribosomal protein S14, zinc-independent	Oenococcus oeni PSU-1 Gene: OEOE_1030: Small subunit ribosomal protein S14, zinc-independent	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0222: Small subunit ribosomal protein S14, zinc-independent	Small subunit ribosomal protein S14, zinc-independent
lp_0947	Lactobacillus acidophilus NCFM	Lactobacillus brevis ATCC 367	* Lactobacillus casei ATCC 334 Site: position = -183 score = 6.37437 sequence = CAAAACGTAATAATTACGATTTA Site: position = -40 score = 6.89799 sequence = TAAATAGTAATGATTACGAATTA Gene: LSEI_2426: Conserved hypothetical protein	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus fermentum IFO 3956	Lactobacillus helveticus DPC 4571	Lactobacillus johnsonii NCC 533	* Lactobacillus plantarum WCFS1 Site: position = -36 score = 6.72556 sequence = TAAATGGTAATAATTACTATTTA Gene: lp_0947: Conserved hypothetical protein	Lactobacillus reuteri JCM 1112	Lactobacillus rhamnosus GG	Lactobacillus sakei subsp. sakei 23K	Lactobacillus salivarius subsp. salivarius UCC118 Gene: LSL_1943: Conserved hypothetical protein	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -65 score = 6.079 sequence = TAAATAGTAATAATTACTATAAT Site: position = -43 score = 6.67214 sequence = TTAAAAGTAATTGTTACTATTTA Gene: LEUM_0082: Conserved hypothetical protein	* Oenococcus oeni PSU-1 Site: position = -42 score = 6.6146 sequence = TAAATAGTAATAATTACTTTTAA Gene: OEOE_0084: Conserved hypothetical protein	Pediococcus pentosaceus ATCC 25745	Conserved hypothetical protein

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Zur - Lactobacillaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --