Regulog PaaR - Burkholderia

Properties
Regulator type:	Transcription factor
Regulator family:	TetR
Regulation mode:	repressor
Biological process:	Phenylacetic acid degradation
Effector:	Phenylacetyl-CoA
Phylum:	Betaproteobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 27 sites [see more]

Member of regulog collections

By trascription factor - PaaR
By taxonomy - Burkholderia
By TF family - TetR
By effector - Phenylacetyl-CoA
By pathway - Phenylacetic acid degradation

Statistics of regulated genes
Genome	Genes	Operons
Burkholderia pseudomallei K96243	13	3
Burkholderia mallei ATCC 23344	13	3
Burkholderia sp. 383	16	4
Burkholderia cepacia AMMD	16	4
Burkholderia glumae BGR1	12	3
Burkholderia vietnamiensis G4	16	4
Burkholderia xenovorans LB400	13	3
Burkholderia phymatum STM815	13	3

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes									Function

CRON 1.
paaH	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	* Burkholderia sp. 383 Site: position = -60 score = 6.30544 sequence = ATATACCGACCGGTCGGTTTAT Gene: Bcep18194_B1317: 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157)	* Burkholderia cepacia AMMD Site: position = -61 score = 6.57719 sequence = ATCTACCGACCGGTCGGTTTAT Gene: Bamb_3960: 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157)	Burkholderia glumae BGR1	* Burkholderia vietnamiensis G4 Site: position = -61 score = 6.57719 sequence = ATCTACCGACCGGTCGGTTTAT Gene: Bcep1808_5069: 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157)	Burkholderia xenovorans LB400	Burkholderia phymatum STM815	3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157)
paaK2	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383 Gene: Bcep18194_B1318: Phenylacetate-coenzyme A ligase (EC 6.2.1.30)	Burkholderia cepacia AMMD Gene: Bamb_3959: Phenylacetate-coenzyme A ligase (EC 6.2.1.30)	Burkholderia glumae BGR1	Burkholderia vietnamiensis G4 Gene: Bcep1808_5068: Phenylacetate-coenzyme A ligase (EC 6.2.1.30)	Burkholderia xenovorans LB400	Burkholderia phymatum STM815	Phenylacetate-coenzyme A ligase (EC 6.2.1.30)
paaF2	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383 Gene: Bcep18194_B1319: Enoyl-CoA hydratase (EC 4.2.1.17)	Burkholderia cepacia AMMD Gene: Bamb_3958: Enoyl-CoA hydratase (EC 4.2.1.17)	Burkholderia glumae BGR1	Burkholderia vietnamiensis G4 Gene: Bcep1808_5067: Enoyl-CoA hydratase (EC 4.2.1.17)	Burkholderia xenovorans LB400	Burkholderia phymatum STM815	Enoyl-CoA hydratase (EC 4.2.1.17)

CRON 2.
paaZ	* Burkholderia pseudomallei K96243 Site: position = -64 score = 6.41721 sequence = TCCGACCAACCGGTCGGTTAAT Gene: BPSL3041: Aldehyde dehydrogenase (EC 1.2.1.3), PaaZ	* Burkholderia mallei ATCC 23344 Site: position = -64 score = 6.01431 sequence = TCCGACTAACCGGTCGGTTAAT Gene: BMAA0543: Aldehyde dehydrogenase (EC 1.2.1.3), PaaZ	* Burkholderia sp. 383 Site: position = -63 score = 6.41721 sequence = TCCGACCAACCGGTCGGTTAAT Gene: Bcep18194_A3630: Aldehyde dehydrogenase (EC 1.2.1.3), PaaZ	* Burkholderia cepacia AMMD Site: position = -63 score = 6.41721 sequence = TCCGACCAACCGGTCGGTTAAT Gene: Bamb_0448: Aldehyde dehydrogenase (EC 1.2.1.3), PaaZ	* Burkholderia glumae BGR1 Site: position = -70 score = 6.23932 sequence = GCCGACCAACCGGTCGGTTAAT Gene: bglu_1g04490: Aldehyde dehydrogenase (EC 1.2.1.3), PaaZ	* Burkholderia vietnamiensis G4 Site: position = -63 score = 6.41721 sequence = TCCGACCAACCGGTCGGTTAAT Gene: Bcep1808_0520: Aldehyde dehydrogenase (EC 1.2.1.3), PaaZ	* Burkholderia xenovorans LB400 Site: position = -66 score = 6.18713 sequence = CCCAACCAACCGGTCGGTCAAT Gene: Bxe_A0470: Aldehyde dehydrogenase (EC 1.2.1.3), PaaZ	* Burkholderia phymatum STM815 Site: position = -68 score = 6.55019 sequence = ACCAACCAACCGGTCGGTCAAT Gene: Bphy_2689: Aldehyde dehydrogenase (EC 1.2.1.3), PaaZ	Aldehyde dehydrogenase (EC 1.2.1.3), PaaZ
paaJ	Burkholderia pseudomallei K96243 Gene: BPSL3042: Beta-ketoadipyl CoA thiolase (EC 2.3.1.-)	Burkholderia mallei ATCC 23344 Gene: BMAA0542: Beta-ketoadipyl CoA thiolase (EC 2.3.1.-)	Burkholderia sp. 383 Gene: Bcep18194_A3629: Beta-ketoadipyl CoA thiolase (EC 2.3.1.-)	Burkholderia cepacia AMMD Gene: Bamb_0447: Beta-ketoadipyl CoA thiolase (EC 2.3.1.-)	Burkholderia glumae BGR1	Burkholderia vietnamiensis G4 Gene: Bcep1808_0519: Beta-ketoadipyl CoA thiolase (EC 2.3.1.-)	Burkholderia xenovorans LB400 Gene: Bxe_A0469: Beta-ketoadipyl CoA thiolase (EC 2.3.1.-)	Burkholderia phymatum STM815 Gene: Bphy_2690: Beta-ketoadipyl CoA thiolase (EC 2.3.1.-)	Beta-ketoadipyl CoA thiolase (EC 2.3.1.-)
paaF	Burkholderia pseudomallei K96243 Gene: BPSL3043: Enoyl-CoA hydratase (EC 4.2.1.17)	Burkholderia mallei ATCC 23344 Gene: BMAA0541: Enoyl-CoA hydratase (EC 4.2.1.17)	Burkholderia sp. 383 Gene: Bcep18194_A3628: Enoyl-CoA hydratase (EC 4.2.1.17)	Burkholderia cepacia AMMD Gene: Bamb_0446: Enoyl-CoA hydratase (EC 4.2.1.17)	Burkholderia glumae BGR1 Gene: bglu_1g04480: Enoyl-CoA hydratase (EC 4.2.1.17)	Burkholderia vietnamiensis G4 Gene: Bcep1808_0518: Enoyl-CoA hydratase (EC 4.2.1.17)	Burkholderia xenovorans LB400 Gene: Bxe_A0468: Enoyl-CoA hydratase (EC 4.2.1.17)	Burkholderia phymatum STM815 Gene: Bphy_2691: Enoyl-CoA hydratase (EC 4.2.1.17)	Enoyl-CoA hydratase (EC 4.2.1.17)
paaY	Burkholderia pseudomallei K96243 Gene: BPSL3044: thioesterase superfamily protein	Burkholderia mallei ATCC 23344 Gene: BMAA0539.1: thioesterase superfamily protein	Burkholderia sp. 383 Gene: Bcep18194_A3627: thioesterase superfamily protein	Burkholderia cepacia AMMD Gene: Bamb_0445: thioesterase superfamily protein	Burkholderia glumae BGR1 Gene: bglu_1g04470: thioesterase superfamily protein	Burkholderia vietnamiensis G4 Gene: Bcep1808_0517: thioesterase superfamily protein	Burkholderia xenovorans LB400 Gene: Bxe_A0467: thioesterase superfamily protein	Burkholderia phymatum STM815 Gene: Bphy_2692: thioesterase superfamily protein	thioesterase superfamily protein
paaK	Burkholderia pseudomallei K96243 Gene: BPSL3045: Phenylacetate-coenzyme A ligase (EC 6.2.1.30)	Burkholderia mallei ATCC 23344 Gene: BMAA0539: Phenylacetate-coenzyme A ligase (EC 6.2.1.30)	Burkholderia sp. 383 Gene: Bcep18194_A3626: Phenylacetate-coenzyme A ligase (EC 6.2.1.30)	Burkholderia cepacia AMMD Gene: Bamb_0444: Phenylacetate-coenzyme A ligase (EC 6.2.1.30)	Burkholderia glumae BGR1 Gene: bglu_1g04460: Phenylacetate-coenzyme A ligase (EC 6.2.1.30)	Burkholderia vietnamiensis G4 Gene: Bcep1808_0516: Phenylacetate-coenzyme A ligase (EC 6.2.1.30)	Burkholderia xenovorans LB400 Gene: Bxe_A0466: Phenylacetate-coenzyme A ligase (EC 6.2.1.30)	Burkholderia phymatum STM815 Gene: Bphy_2693: Phenylacetate-coenzyme A ligase (EC 6.2.1.30)	Phenylacetate-coenzyme A ligase (EC 6.2.1.30)

CRON 3.
paaA	* Burkholderia pseudomallei K96243 Site: position = -62 score = 7.10894 sequence = ATTAACCGACCGGTCGGTTGGT Gene: BPSL3230: Phenylacetate-CoA oxygenase, PaaA subunit	* Burkholderia mallei ATCC 23344 Site: position = -62 score = 7.10894 sequence = ATTAACCGACCGGTCGGTTGGT Gene: BMA2573: Phenylacetate-CoA oxygenase, PaaA subunit	* Burkholderia sp. 383 Site: position = -61 score = 7.10894 sequence = ATTAACCGACCGGTCGGTTGGT Gene: Bcep18194_A3429: Phenylacetate-CoA oxygenase, PaaA subunit	* Burkholderia cepacia AMMD Site: position = -62 score = 7.10894 sequence = ATTAACCGACCGGTCGGTTGGT Gene: Bamb_0249: Phenylacetate-CoA oxygenase, PaaA subunit	* Burkholderia glumae BGR1 Site: position = -62 score = 6.77945 sequence = ATTAACCGACCGGACGGTTGGT Gene: bglu_1g02410: Phenylacetate-CoA oxygenase, PaaA subunit	* Burkholderia vietnamiensis G4 Site: position = -62 score = 7.10894 sequence = ATTAACCGACCGGTCGGTTGGT Gene: Bcep1808_0312: Phenylacetate-CoA oxygenase, PaaA subunit	* Burkholderia xenovorans LB400 Site: position = -65 score = 7.10894 sequence = ATTAACCGACCGGTCGGTTGGT Gene: Bxe_A0295: Phenylacetate-CoA oxygenase, PaaA subunit	* Burkholderia phymatum STM815 Site: position = -66 score = 6.77945 sequence = ATTAACCGACCGGACGGTTGGT Gene: Bphy_2857: Phenylacetate-CoA oxygenase, PaaA subunit	Phenylacetate-CoA oxygenase, PaaA subunit
paaB	Burkholderia pseudomallei K96243 Gene: BPSL3231: Phenylacetate-CoA oxygenase, PaaB subunit	Burkholderia mallei ATCC 23344 Gene: BMA2574: Phenylacetate-CoA oxygenase, PaaB subunit	Burkholderia sp. 383 Gene: Bcep18194_A3428: Phenylacetate-CoA oxygenase, PaaB subunit	Burkholderia cepacia AMMD Gene: Bamb_0248: Phenylacetate-CoA oxygenase, PaaB subunit	Burkholderia glumae BGR1 Gene: bglu_1g02400: Phenylacetate-CoA oxygenase, PaaB subunit	Burkholderia vietnamiensis G4 Gene: Bcep1808_0311: Phenylacetate-CoA oxygenase, PaaB subunit	Burkholderia xenovorans LB400 Gene: Bxe_A0294: Phenylacetate-CoA oxygenase, PaaB subunit	Burkholderia phymatum STM815 Gene: Bphy_2858: Phenylacetate-CoA oxygenase, PaaB subunit	Phenylacetate-CoA oxygenase, PaaB subunit
paaC	Burkholderia pseudomallei K96243 Gene: BPSL3232: Phenylacetate-CoA oxygenase, PaaC subunit	Burkholderia mallei ATCC 23344 Gene: BMA2575: Phenylacetate-CoA oxygenase, PaaC subunit	Burkholderia sp. 383 Gene: Bcep18194_A3427: Phenylacetate-CoA oxygenase, PaaC subunit	Burkholderia cepacia AMMD Gene: Bamb_0247: Phenylacetate-CoA oxygenase, PaaC subunit	Burkholderia glumae BGR1 Gene: bglu_1g02390: Phenylacetate-CoA oxygenase, PaaC subunit	Burkholderia vietnamiensis G4 Gene: Bcep1808_0310: Phenylacetate-CoA oxygenase, PaaC subunit	Burkholderia xenovorans LB400 Gene: Bxe_A0293: Phenylacetate-CoA oxygenase, PaaC subunit	Burkholderia phymatum STM815 Gene: Bphy_2859: Phenylacetate-CoA oxygenase, PaaC subunit	Phenylacetate-CoA oxygenase, PaaC subunit
paaD	Burkholderia pseudomallei K96243 Gene: BPSL3233: Phenylacetate-CoA oxygenase, PaaD subunit	Burkholderia mallei ATCC 23344 Gene: BMA2576: Phenylacetate-CoA oxygenase, PaaD subunit	Burkholderia sp. 383 Gene: Bcep18194_A3426: Phenylacetate-CoA oxygenase, PaaD subunit	Burkholderia cepacia AMMD Gene: Bamb_0246: Phenylacetate-CoA oxygenase, PaaD subunit	Burkholderia glumae BGR1 Gene: bglu_1g02380: Phenylacetate-CoA oxygenase, PaaD subunit	Burkholderia vietnamiensis G4 Gene: Bcep1808_0309: Phenylacetate-CoA oxygenase, PaaD subunit	Burkholderia xenovorans LB400 Gene: Bxe_A0292: Phenylacetate-CoA oxygenase, PaaD subunit	Burkholderia phymatum STM815 Gene: Bphy_2860: Phenylacetate-CoA oxygenase, PaaD subunit	Phenylacetate-CoA oxygenase, PaaD subunit
paaE	Burkholderia pseudomallei K96243 Gene: BPSL3234: Probable phenylacetic acid degradation NADH oxidoreductase paaE (EC 1.-.-.-)	Burkholderia mallei ATCC 23344 Gene: BMA2577: Probable phenylacetic acid degradation NADH oxidoreductase paaE (EC 1.-.-.-)	Burkholderia sp. 383 Gene: Bcep18194_A3425: Probable phenylacetic acid degradation NADH oxidoreductase paaE (EC 1.-.-.-)	Burkholderia cepacia AMMD Gene: Bamb_0245: Probable phenylacetic acid degradation NADH oxidoreductase paaE (EC 1.-.-.-)	Burkholderia glumae BGR1 Gene: bglu_1g02370: Probable phenylacetic acid degradation NADH oxidoreductase paaE (EC 1.-.-.-)	Burkholderia vietnamiensis G4 Gene: Bcep1808_0308: Probable phenylacetic acid degradation NADH oxidoreductase paaE (EC 1.-.-.-)	Burkholderia xenovorans LB400 Gene: Bxe_A0291: Probable phenylacetic acid degradation NADH oxidoreductase paaE (EC 1.-.-.-)	Burkholderia phymatum STM815 Gene: Bphy_2861: Probable phenylacetic acid degradation NADH oxidoreductase paaE (EC 1.-.-.-)	Probable phenylacetic acid degradation NADH oxidoreductase paaE (EC 1.-.-.-)
paaW	Burkholderia pseudomallei K96243 Gene: BPSL3235: Protein of unknown function DUF3658/DUF1835	Burkholderia mallei ATCC 23344 Gene: BMA2578: Protein of unknown function DUF3658/DUF1835	Burkholderia sp. 383 Gene: Bcep18194_A3424: Protein of unknown function DUF3658/DUF1835	Burkholderia cepacia AMMD Gene: Bamb_0244: Protein of unknown function DUF3658/DUF1835	Burkholderia glumae BGR1 Gene: bglu_1g02360: Protein of unknown function DUF3658/DUF1835	Burkholderia vietnamiensis G4 Gene: Bcep1808_0307: Protein of unknown function DUF3658/DUF1835	Burkholderia xenovorans LB400 Gene: Bxe_A0290: Protein of unknown function DUF3658/DUF1835	Burkholderia phymatum STM815 Gene: Bphy_2862: Protein of unknown function DUF3658/DUF1835	Protein of unknown function DUF3658/DUF1835
paaR	Burkholderia pseudomallei K96243 Gene: BPSL3236: Transcriptional regulator of phenylacetic acid degradation, TetR family	Burkholderia mallei ATCC 23344 Gene: BMA2579: Transcriptional regulator of phenylacetic acid degradation, TetR family	Burkholderia sp. 383 Gene: Bcep18194_A3423: Transcriptional regulator of phenylacetic acid degradation, TetR family	Burkholderia cepacia AMMD Gene: Bamb_0243: Transcriptional regulator of phenylacetic acid degradation, TetR family	Burkholderia glumae BGR1 Gene: bglu_1g02350: Transcriptional regulator of phenylacetic acid degradation, TetR family	Burkholderia vietnamiensis G4 Gene: Bcep1808_0306: Transcriptional regulator of phenylacetic acid degradation, TetR family	Burkholderia xenovorans LB400 Gene: Bxe_A0289: Transcriptional regulator of phenylacetic acid degradation, TetR family	Burkholderia phymatum STM815 Gene: Bphy_2863: Transcriptional regulator of phenylacetic acid degradation, TetR family	Transcriptional regulator of phenylacetic acid degradation, TetR family

CRON 4.
paaG	* Burkholderia pseudomallei K96243 Site: position = -70 score = 6.6069 sequence = ATTAACCGACCGGTTGGTCGGA Gene: BPSL3040: Enoyl-CoA hydratase (EC 4.2.1.17)	* Burkholderia mallei ATCC 23344 Site: position = -88 score = 6.07262 sequence = ATTAACCGACCGGTTAGTCGGA Gene: BMAA0544: Enoyl-CoA hydratase (EC 4.2.1.17)	* Burkholderia sp. 383 Site: position = -88 score = 6.6069 sequence = ATTAACCGACCGGTTGGTCGGA Gene: Bcep18194_A3631: Enoyl-CoA hydratase (EC 4.2.1.17)	* Burkholderia cepacia AMMD Site: position = -88 score = 6.6069 sequence = ATTAACCGACCGGTTGGTCGGA Gene: Bamb_0449: Enoyl-CoA hydratase (EC 4.2.1.17)	* Burkholderia glumae BGR1 Site: position = -87 score = 6.45764 sequence = ATTAACCGACCGGTTGGTCGGC Gene: bglu_1g04500: Enoyl-CoA hydratase (EC 4.2.1.17)	* Burkholderia vietnamiensis G4 Site: position = -88 score = 6.6069 sequence = ATTAACCGACCGGTTGGTCGGA Gene: Bcep1808_0521: Enoyl-CoA hydratase (EC 4.2.1.17)	* Burkholderia xenovorans LB400 Site: position = -93 score = 6.50983 sequence = ATTGACCGACCGGTTGGTTGGG Gene: Bxe_A0471: Enoyl-CoA hydratase (EC 4.2.1.17)	* Burkholderia phymatum STM815 Site: position = -90 score = 6.88031 sequence = ATTGACCGACCGGTTGGTTGGT Gene: Bphy_2688: Enoyl-CoA hydratase (EC 4.2.1.17)	Enoyl-CoA hydratase (EC 4.2.1.17)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog PaaR - Burkholderia

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --