Regulog MetJ - Enterobacteriales

Properties
Regulator type:	Transcription factor
Regulator family:	MetJ
Regulation mode:	repressor
Biological process:	Methionine metabolism; Methionine biosynthesis
Effector:	S-adenosylmethionine
Phylum:	Proteobacteria/Gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 167 sites [see more]

Member of regulog collections

By taxonomy - Enterobacteriales
By trascription factor - MetJ
By TF family - MetJ
By effector - S-adenosylmethionine
By pathway - Methionine metabolism
By pathway - Methionine biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Citrobacter koseri ATCC BAA-895	26	18
Edwardsiella tarda EIB202	10	7
Enterobacter sp. 638	29	19
Erwinia amylovora ATCC 49946	17	12
Erwinia carotovora subsp. atroseptica SCRI1043	25	17
Escherichia coli str. K-12 substr. MG1655	20	15
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	29	20
Photorhabdus luminescens subsp. laumondii TTO1	14	10
Proteus mirabilis HI4320	13	10
Salmonella typhimurium LT2	16	12
Serratia proteamaculans 568	26	18
Yersinia pestis KIM	12	9

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes													Function

CRON 1.
metF	* Citrobacter koseri ATCC BAA-895 Site: position = -65 score = 6.74847 sequence = AGACGTCT-(0)-AAACGGAT Gene: CKO_03051: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	* Edwardsiella tarda EIB202 Site: position = -70 score = 7.30036 sequence = AGACGTCT-(0)-AAACGTAT Gene: ETAE_3485: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	* Enterobacter sp. 638 Site: position = -64 score = 6.62239 sequence = AGACGTCT-(0)-AAATGGAT Gene: Ent638_4033: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	* Erwinia amylovora ATCC 49946 Site: position = -61 score = 6.74838 sequence = GAATGTCT-(0)-GGACGTCT Gene: EAM_0135: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -65 score = 7.30036 sequence = AGACGTCT-(0)-AAACGTAT Gene: ECA4244: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	* Escherichia coli str. K-12 substr. MG1655 Site: position = -65 score = 6.40395 sequence = GGACGTCT-(0)-AAACGGAT Gene: b3941: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -64 score = 6.95584 sequence = GGACGTCT-(0)-AAACGTAT Gene: KPN_04239: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	* Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -97 score = 6.95584 sequence = GGACGTCT-(0)-AAACGTAT Gene: plu4754: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	* Proteus mirabilis HI4320 Site: position = -92 score = 6.64829 sequence = AGACGTCT-(0)-AAATGGTT Gene: PMI2932: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	* Salmonella typhimurium LT2 Site: position = -65 score = 6.40395 sequence = GGACGTCT-(0)-AAACGGAT Gene: STM4105: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	* Serratia proteamaculans 568 Site: position = -68 score = 7.30036 sequence = AGACGTCT-(0)-AAACGTAT Gene: Spro_4784: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	* Yersinia pestis KIM Site: position = -77 score = 7.30036 sequence = AGACGTCT-(0)-AAACGTAT Gene: y0304: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)

CRON 2.
metE	* Citrobacter koseri ATCC BAA-895 Site: position = -177 score = 6.77121 sequence = AAACATCT-(0)-GGACGTCT Gene: CKO_00171: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	* Edwardsiella tarda EIB202 Site: position = -59 score = 6.4246 sequence = AGATGTGT-(0)-AAACATCT Gene: ETAE_0142: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	* Enterobacter sp. 638 Site: position = -176 score = 6.27082 sequence = AAACATCT-(0)-GGACGTCC Gene: Ent638_3967: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	* Erwinia amylovora ATCC 49946 Site: position = -78 score = 6.27082 sequence = AAACATCT-(0)-GGACGTCC Gene: EAM_0198: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -32 score = 6.21932 sequence = AAACATCT-(0)-GGACGGCT Gene: ECA0181: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	* Escherichia coli str. K-12 substr. MG1655 Site: position = -165 score = 6.21932 sequence = AAACATCT-(0)-GGACGGCT Gene: b3829: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -176 score = 6.77121 sequence = AAACATCT-(0)-GGACGTCT Gene: KPN_04325: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	* Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -36 score = 6.56384 sequence = AAACATCT-(0)-AGACGGCT Gene: plu4420: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	* Proteus mirabilis HI4320 Site: position = -35 score = 6.56384 sequence = AAACATCT-(0)-AGACGGCT Gene: PMI3529: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	* Salmonella typhimurium LT2 Site: position = -177 score = 6.61533 sequence = AAACATCC-(0)-AGACGTCT Gene: STM3965: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	* Serratia proteamaculans 568 Site: position = -33 score = 6.21932 sequence = AAACATCT-(0)-GGACGGCT Gene: Spro_0242: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	* Yersinia pestis KIM Site: position = -26 score = 6.4246 sequence = AGATGTGT-(0)-AAACATCT Gene: y0442: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

CRON 3.
metA	* Citrobacter koseri ATCC BAA-895 Site: position = -43 score = 6.85567 sequence = GGATGTCT-(0)-AAACGTTT Gene: CKO_03907: Homoserine O-succinyltransferase (EC 2.3.1.46)	* Edwardsiella tarda EIB202 Site: position = -58 score = 5.83744 sequence = AGCTATCT-(0)-AGATGTCC Gene: ETAE_3190: Homoserine O-succinyltransferase (EC 2.3.1.46)	* Enterobacter sp. 638 Site: position = -43 score = 6.85567 sequence = GGATGTCT-(0)-AAACGTTT Gene: Ent638_0217: Homoserine O-succinyltransferase (EC 2.3.1.46)	* Erwinia amylovora ATCC 49946 Site: position = -42 score = 6.82976 sequence = GGATGTCT-(0)-AAACGTAT Gene: EAM_0250: Homoserine O-succinyltransferase (EC 2.3.1.46)	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -43 score = 6.85567 sequence = GGATGTCT-(0)-AAACGTTT Gene: ECA3992: Homoserine O-succinyltransferase (EC 2.3.1.46)	* Escherichia coli str. K-12 substr. MG1655 Site: position = -43 score = 6.82976 sequence = GGATGTCT-(0)-AAACGTAT Gene: b4013: Homoserine O-succinyltransferase (EC 2.3.1.46)	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -43 score = 6.85567 sequence = GGATGTCT-(0)-AAACGTTT Gene: KPN_04394: Homoserine O-succinyltransferase (EC 2.3.1.46)	* Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -44 score = 6.64163 sequence = AGAAGTCT-(0)-AAACGTGT Gene: plu4397: Homoserine O-succinyltransferase (EC 2.3.1.46)	* Proteus mirabilis HI4320 Site: position = -33 score = 7.30596 sequence = AGATGTCT-(0)-AGATGTTT Gene: PMI2765: Homoserine O-succinyltransferase (EC 2.3.1.46)	* Salmonella typhimurium LT2 Site: position = -43 score = 6.85567 sequence = GGATGTCT-(0)-AAACGTTT Gene: STM4182: Homoserine O-succinyltransferase (EC 2.3.1.46)	* Serratia proteamaculans 568 Site: position = -40 score = 6.96945 sequence = AGAAGTCT-(0)-AAACGTTT Gene: Spro_4504: Homoserine O-succinyltransferase (EC 2.3.1.46)	* Yersinia pestis KIM Site: position = -41 score = 6.94354 sequence = AGAAGTCT-(0)-AAACGTAT Gene: y0013: Homoserine O-succinyltransferase (EC 2.3.1.46)	Homoserine O-succinyltransferase (EC 2.3.1.46)

CRON 4.
metR	* Citrobacter koseri ATCC BAA-895 Site: position = -87 score = 6.93165 sequence = AGACGTCC-(0)-AGATGTTT Gene: CKO_00170: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family	Edwardsiella tarda EIB202	* Enterobacter sp. 638 Site: position = -87 score = 6.58714 sequence = GGACGTCC-(0)-AGATGTTT Gene: Ent638_3968: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family	* Erwinia amylovora ATCC 49946 Site: position = -88 score = 6.58714 sequence = GGACGTCC-(0)-AGATGTTT Gene: EAM_0197: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -88 score = 6.17406 sequence = AGCCGTCC-(0)-AGATGTTT Gene: ECA0180: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family	* Escherichia coli str. K-12 substr. MG1655 Site: position = -87 score = 6.17406 sequence = AGCCGTCC-(0)-AGATGTTT Gene: b3828: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -87 score = 6.93165 sequence = AGACGTCC-(0)-AGATGTTT Gene: KPN_04324: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family	* Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -88 score = 6.67445 sequence = AGCCGTCT-(0)-AGATGTTT Gene: plu4421: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family	* Proteus mirabilis HI4320 Site: position = -88 score = 6.67445 sequence = AGCCGTCT-(0)-AGATGTTT Gene: PMI3528: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family	* Salmonella typhimurium LT2 Site: position = -87 score = 7.08753 sequence = AGACGTCT-(0)-GGATGTTT Gene: STM3964: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family	* Serratia proteamaculans 568 Site: position = -88 score = 6.17406 sequence = AGCCGTCC-(0)-AGATGTTT Gene: Spro_0241: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family	* Yersinia pestis KIM Site: position = -80 score = 6.00384 sequence = AGATGTTT-(0)-ACACATCT Gene: y0441: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family	Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family

CRON 5.
metN	* Citrobacter koseri ATCC BAA-895 Site: position = -99 score = 6.57879 sequence = AGACGTCT-(0)-GGATGCCT Gene: CKO_03166: Methionine ABC transporter ATP-binding protein	* Edwardsiella tarda EIB202 Site: position = -95 score = 7.04939 sequence = AGACGTCT-(0)-AGACGCCT Gene: ETAE_0553: Methionine ABC transporter ATP-binding protein	* Enterobacter sp. 638 Site: position = -100 score = 6.57879 sequence = AGACGTCT-(0)-GGATGCCT Gene: Ent638_0737: Methionine ABC transporter ATP-binding protein	* Erwinia amylovora ATCC 49946 Site: position = -100 score = 6.57879 sequence = AGACGTCT-(0)-GGATGCCT Gene: EAM_0849: Methionine ABC transporter ATP-binding protein	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -87 score = 5.7914 sequence = AGCCGTCT-(0)-AGACGCCC Gene: ECA3524: Methionine ABC transporter ATP-binding protein	* Escherichia coli str. K-12 substr. MG1655 Site: position = -98 score = 6.57879 sequence = AGACGTCT-(0)-GGATGCCT Gene: b0199: Methionine ABC transporter ATP-binding protein	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -100 score = 6.57879 sequence = AGACGTCT-(0)-GGATGCCT Gene: KPN_00213: Methionine ABC transporter ATP-binding protein	* Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -105 score = 6.60162 sequence = AGACGTCT-(0)-AGACACCT Gene: plu0697: Methionine ABC transporter ATP-binding protein	* Proteus mirabilis HI4320 Site: position = -82 score = 6.70487 sequence = GGACGTCT-(0)-AGACGCCT Gene: PMI2259: Methionine ABC transporter ATP-binding protein	* Salmonella typhimurium LT2 Site: position = -99 score = 6.57879 sequence = AGACGTCT-(0)-GGATGCCT Gene: STM0247: Methionine ABC transporter ATP-binding protein	* Serratia proteamaculans 568 Site: position = -96 score = 6.70487 sequence = GGACGTCT-(0)-AGACGCCT Gene: Spro_3753: Methionine ABC transporter ATP-binding protein	* Yersinia pestis KIM Site: position = -95 score = 6.29179 sequence = AGCCGTCT-(0)-AGACGCCT Gene: y3104: Methionine ABC transporter ATP-binding protein	Methionine ABC transporter ATP-binding protein
metI	Citrobacter koseri ATCC BAA-895 Gene: CKO_03167: Methionine ABC transporter permease protein	Edwardsiella tarda EIB202 Gene: ETAE_0552: Methionine ABC transporter permease protein	Enterobacter sp. 638 Gene: Ent638_0736: Methionine ABC transporter permease protein	Erwinia amylovora ATCC 49946 Gene: EAM_0848: Methionine ABC transporter permease protein	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA3525: Methionine ABC transporter permease protein	Escherichia coli str. K-12 substr. MG1655 Gene: b0198: Methionine ABC transporter permease protein	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_00212: Methionine ABC transporter permease protein	Photorhabdus luminescens subsp. laumondii TTO1 Gene: plu0696: Methionine ABC transporter permease protein	Proteus mirabilis HI4320 Gene: PMI2260: Methionine ABC transporter permease protein	Salmonella typhimurium LT2 Gene: STM0246: Methionine ABC transporter permease protein	Serratia proteamaculans 568 Gene: Spro_3754: Methionine ABC transporter permease protein	Yersinia pestis KIM Gene: y3105: Methionine ABC transporter permease protein	Methionine ABC transporter permease protein
metQ	Citrobacter koseri ATCC BAA-895 Gene: CKO_03168: Methionine ABC transporter substrate-binding protein	Edwardsiella tarda EIB202 Gene: ETAE_0551: Methionine ABC transporter substrate-binding protein	Enterobacter sp. 638 Gene: Ent638_0735: Methionine ABC transporter substrate-binding protein	Erwinia amylovora ATCC 49946 Gene: EAM_0847: Methionine ABC transporter substrate-binding protein	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA3526: Methionine ABC transporter substrate-binding protein	Escherichia coli str. K-12 substr. MG1655 Gene: b0197: Methionine ABC transporter substrate-binding protein	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_00211: Methionine ABC transporter substrate-binding protein	Photorhabdus luminescens subsp. laumondii TTO1 Gene: plu0695: Methionine ABC transporter substrate-binding protein	Proteus mirabilis HI4320 Gene: PMI2261: Methionine ABC transporter substrate-binding protein	Salmonella typhimurium LT2 Gene: STM0245: Methionine ABC transporter substrate-binding protein	Serratia proteamaculans 568 Gene: Spro_3755: Methionine ABC transporter substrate-binding protein	Yersinia pestis KIM Gene: y3106: Methionine ABC transporter substrate-binding protein	Methionine ABC transporter substrate-binding protein

CRON 6.
mtnK	* Citrobacter koseri ATCC BAA-895 Site: position = -35 score = 7.40614 sequence = AGATGTAT-(0)-AGACGTCT Gene: CKO_03975: 5-methylthioribose kinase (EC 2.7.1.100)	Edwardsiella tarda EIB202	* Enterobacter sp. 638 Site: position = -44 score = 7.43741 sequence = AGACGTCT-(0)-AAATGTCT Gene: Ent638_1139: 5-methylthioribose kinase (EC 2.7.1.100)	* Erwinia amylovora ATCC 49946 Site: position = -64 score = 7.06163 sequence = GGATGTAT-(0)-AGACGTCT Gene: EAM_0889: 5-methylthioribose kinase (EC 2.7.1.100)	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -65 score = 6.90575 sequence = AGATGTAT-(0)-AGACGTCC Gene: ECA3476: 5-methylthioribose kinase (EC 2.7.1.100)	Escherichia coli str. K-12 substr. MG1655	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -49 score = 7.1754 sequence = AGAAGTAT-(0)-AGACGTCT Gene: KPN_00626: 5-methylthioribose kinase (EC 2.7.1.100)	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2	* Serratia proteamaculans 568 Site: position = -79 score = 6.56123 sequence = GGATGTAT-(0)-AGACGTCC Gene: Spro_0946: 5-methylthioribose kinase (EC 2.7.1.100)	Yersinia pestis KIM	5-methylthioribose kinase (EC 2.7.1.100)

CRON 7.
mtnB	* Citrobacter koseri ATCC BAA-895 Site: position = -56 score = 6.68608 sequence = AGACGCTT-(0)-AGATGTCT Gene: CKO_03971: Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)	Edwardsiella tarda EIB202	* Enterobacter sp. 638 Site: position = -57 score = 6.81216 sequence = AGACGCTT-(0)-AGACGTCT Gene: Ent638_1143: Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)	* Erwinia amylovora ATCC 49946 Site: position = -75 score = 6.81216 sequence = AGACGCTT-(0)-AGACGTCT Gene: EAM_0885: Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -105 score = 6.30378 sequence = GGACGTTT-(0)-AAATGGCT Gene: ECA3487: Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)	Escherichia coli str. K-12 substr. MG1655	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -47 score = 5.80087 sequence = AGCCATTT-(0)-AGACGGCT Gene: KPN_00634: Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2	* Serratia proteamaculans 568 Site: position = -88 score = 6.13419 sequence = AGACGCTT-(0)-AGATGGCT Gene: Spro_0942: Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)	Yersinia pestis KIM	Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)
mtnC	Citrobacter koseri ATCC BAA-895 Gene: CKO_03972: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)	Edwardsiella tarda EIB202	Enterobacter sp. 638 Gene: Ent638_1142: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)	Erwinia amylovora ATCC 49946 Gene: EAM_0886: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA3486: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)	Escherichia coli str. K-12 substr. MG1655	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -59 score = 6.81216 sequence = AGACGCTT-(0)-AGACGTCT Gene: KPN_00644: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2	Serratia proteamaculans 568 Gene: Spro_0943: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)	Yersinia pestis KIM	2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)
mtnD	Citrobacter koseri ATCC BAA-895 Gene: CKO_03973: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)	Edwardsiella tarda EIB202	Enterobacter sp. 638 Gene: Ent638_1141: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)	Erwinia amylovora ATCC 49946 Gene: EAM_0887: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)	2 Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA3485: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) Gene: ECA2986: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)	Escherichia coli str. K-12 substr. MG1655	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_00643: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2	Serratia proteamaculans 568 Gene: Spro_0944: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)	Yersinia pestis KIM	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)

CRON 8.
mtnA	* Citrobacter koseri ATCC BAA-895 Site: position = -76 score = 6.78254 sequence = AGACATGT-(0)-AGACGTCT Gene: CKO_03974: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)	Edwardsiella tarda EIB202	* Enterobacter sp. 638 Site: position = -76 score = 7.11036 sequence = AGACATTT-(0)-AGACGTCT Gene: Ent638_1140: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)	* Erwinia amylovora ATCC 49946 Site: position = -75 score = 6.30014 sequence = AGCCGTTC-(0)-AGACGTCT Gene: EAM_0888: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -77 score = 6.48136 sequence = AAACGTTC-(0)-GGACGTCT Gene: ECA3477: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)	Escherichia coli str. K-12 substr. MG1655	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -76 score = 6.30014 sequence = AGCCGTTC-(0)-AGACGTCT Gene: KPN_00627: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2	* Serratia proteamaculans 568 Site: position = -80 score = 5.81221 sequence = GGACGTCT-(0)-ATACATCC Gene: Spro_0945: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)	Yersinia pestis KIM	Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)

CRON 9.
mmuP	Citrobacter koseri ATCC BAA-895	Edwardsiella tarda EIB202	* Enterobacter sp. 638 Site: position = -10 score = 6.46106 sequence = GGATGTTT-(0)-AGATGTCC Gene: Ent638_0827: S-methylmethionine transporter	Erwinia amylovora ATCC 49946	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -87 score = 6.86216 sequence = GGAAGTCT-(0)-AAACGTCT Gene: ECA2798: S-methylmethionine transporter	* Escherichia coli str. K-12 substr. MG1655 Site: position = -34 score = 6.46106 sequence = GGATGTTT-(0)-AGATGTCC Gene: b0260: S-methylmethionine transporter	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -69 score = 6.96145 sequence = GGATGTTT-(0)-AGATGTCT Gene: KPN_00309: S-methylmethionine transporter	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2	* Serratia proteamaculans 568 Site: position = -32 score = 6.67445 sequence = AGCTGTTT-(0)-AGACGTCT Gene: Spro_3470: S-methylmethionine transporter	Yersinia pestis KIM	S-methylmethionine transporter
mmuM	Citrobacter koseri ATCC BAA-895 Gene: CKO_02822: Homocysteine S-methyltransferase (EC 2.1.1.10)	Edwardsiella tarda EIB202	Enterobacter sp. 638 Gene: Ent638_0828: Homocysteine S-methyltransferase (EC 2.1.1.10)	Erwinia amylovora ATCC 49946	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA2797: Homocysteine S-methyltransferase (EC 2.1.1.10)	Escherichia coli str. K-12 substr. MG1655 Gene: b0261: Homocysteine S-methyltransferase (EC 2.1.1.10)	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_00310: Homocysteine S-methyltransferase (EC 2.1.1.10)	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2	Serratia proteamaculans 568 Gene: Spro_3471: Homocysteine S-methyltransferase (EC 2.1.1.10)	Yersinia pestis KIM	Homocysteine S-methyltransferase (EC 2.1.1.10)

CRON 10.
metJ	* Citrobacter koseri ATCC BAA-895 Site: position = -189 score = 5.93119 sequence = GGACATCT-(0)-AAACTTCT Gene: CKO_03057: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Edwardsiella tarda EIB202 Site: position = -209 score = 6.00131 sequence = AGCCATCT-(0)-AAAAGTCT Gene: ETAE_3431: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Enterobacter sp. 638 Site: position = -200 score = 5.93119 sequence = GGACATCT-(0)-AAACTTCT Gene: Ent638_4036: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Erwinia amylovora ATCC 49946 Site: position = -169 score = 6.25288 sequence = GGACTTCT-(0)-AAATGTCT Gene: EAM_0132: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -110 score = 6.27571 sequence = AGACATCT-(0)-AAACTTCT Gene: ECA4253: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Escherichia coli str. K-12 substr. MG1655 Site: position = -197 score = 5.93119 sequence = GGACATCT-(0)-AAACTTCT Gene: b3938: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -189 score = 5.93119 sequence = GGACATCT-(0)-AAACTTCT Gene: KPN_04232: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -214 score = 6.20011 sequence = AGACATCT-(0)-AAACCTCT Gene: plu4757: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Proteus mirabilis HI4320 Site: position = -215 score = 6.20935 sequence = ATACATCT-(0)-AGACATCT Gene: PMI3222: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Salmonella typhimurium LT2 Site: position = -188 score = 5.93119 sequence = GGACATCT-(0)-AAACTTCT Gene: STM4099: S-adenosylmethionine-responsive transcriptional repressor MetJ	* Serratia proteamaculans 568 Site: position = -240 score = 5.93119 sequence = GGACATCT-(0)-AAACTTCT Gene: Spro_4787: S-adenosylmethionine-responsive transcriptional repressor MetJ	Yersinia pestis KIM Gene: y0301: S-adenosylmethionine-responsive transcriptional repressor MetJ	S-adenosylmethionine-responsive transcriptional repressor MetJ

CRON 11.
ahpC	* Citrobacter koseri ATCC BAA-895 Site: position = -10 score = 6.20442 sequence = GGAAGTAT-(0)-AGATGTCC Gene: CKO_02554: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)	Edwardsiella tarda EIB202	* Enterobacter sp. 638 Site: position = -10 score = 5.70402 sequence = GGAAGTAC-(0)-AGATGTCC Gene: Ent638_1145: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)	Erwinia amylovora ATCC 49946	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA3942: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)	* Escherichia coli str. K-12 substr. MG1655 Site: position = -10 score = 6.20442 sequence = GGAAGTAT-(0)-AGATGTCC Gene: b0605: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -10 score = 6.20442 sequence = GGAAGTAT-(0)-AGATGTCC Gene: KPN_00650: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320 Gene: PMI1213: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)	* Salmonella typhimurium LT2 Site: position = -10 score = 6.20442 sequence = GGAAGTAT-(0)-AGATGTCC Gene: STM0608: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)	Serratia proteamaculans 568	Yersinia pestis KIM	Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)
ahpF	Citrobacter koseri ATCC BAA-895 Gene: CKO_02552: Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)	Edwardsiella tarda EIB202	Enterobacter sp. 638 Gene: Ent638_1146: Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)	Erwinia amylovora ATCC 49946	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA3941: Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)	Escherichia coli str. K-12 substr. MG1655 Gene: b0606: Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_00651: Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320 Gene: PMI1214: Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)	Salmonella typhimurium LT2 Gene: STM0609: Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)	Serratia proteamaculans 568	Yersinia pestis KIM	Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)

CRON 12.
ybdH	* Citrobacter koseri ATCC BAA-895 Site: position = -62 score = 6.81216 sequence = AGACGCTT-(0)-AGACGTCT Gene: CKO_02560: Uncharacterized oxidoreductase YbdH	Edwardsiella tarda EIB202	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Erwinia carotovora subsp. atroseptica SCRI1043	* Escherichia coli str. K-12 substr. MG1655 Site: position = -42 score = 7.43205 sequence = AGACGTTT-(0)-AGATGTCT Gene: b0599: Uncharacterized oxidoreductase YbdH	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	* Salmonella typhimurium LT2 Site: position = -59 score = 7.43205 sequence = AGACGTTT-(0)-AGATGTCT Gene: STM0602: Uncharacterized oxidoreductase YbdH	Serratia proteamaculans 568 Gene: Spro_2371: Uncharacterized oxidoreductase YbdH	Yersinia pestis KIM	Uncharacterized oxidoreductase YbdH

CRON 13.
metE2	* Citrobacter koseri ATCC BAA-895 Site: position = -76 score = 5.73278 sequence = AGCCATCC-(0)-AGAAGTCT Gene: CKO_01563: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)	Edwardsiella tarda EIB202	* Enterobacter sp. 638 Site: position = -70 score = 5.89521 sequence = AGAAGTCT-(0)-AAATATTC Gene: Ent638_1987: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)	* Erwinia amylovora ATCC 49946 Site: position = -84 score = 6.93814 sequence = AGACGTCC-(0)-AGAAGTCT Gene: EAM_0952: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -126 score = 6.61699 sequence = AGACGTCC-(0)-AGATGGCT Gene: ECA1113: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)	Escherichia coli str. K-12 substr. MG1655	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -78 score = 5.73278 sequence = AGCCATCC-(0)-AGAAGTCT Gene: KPN_01615: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2	* Serratia proteamaculans 568 Site: position = -97 score = 6.82437 sequence = AGACGTCT-(0)-GGATGTCC Gene: Spro_1044: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)	Yersinia pestis KIM	Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)

CRON 14.
metQ2	Citrobacter koseri ATCC BAA-895	Edwardsiella tarda EIB202	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Erwinia carotovora subsp. atroseptica SCRI1043	Escherichia coli str. K-12 substr. MG1655	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Photorhabdus luminescens subsp. laumondii TTO1	* Proteus mirabilis HI4320 Site: position = -135 score = 7.43741 sequence = AAACGTCT-(0)-AGATGTCT Gene: PMI3020: Methionine ABC transporter substrate-binding protein	Salmonella typhimurium LT2	Serratia proteamaculans 568	Yersinia pestis KIM	Methionine ABC transporter substrate-binding protein

CRON 15.
folE	* Citrobacter koseri ATCC BAA-895 Site: position = -10 score = 4.74559 sequence = AGAAGAAT-(0)-AAATGTCA Gene: CKO_00638: GTP cyclohydrolase I (EC 3.5.4.16) type 1	Edwardsiella tarda EIB202 Gene: ETAE_1155: GTP cyclohydrolase I (EC 3.5.4.16) type 1	Enterobacter sp. 638 Gene: Ent638_2753: GTP cyclohydrolase I (EC 3.5.4.16) type 1	Erwinia amylovora ATCC 49946 Gene: EAM_2210: GTP cyclohydrolase I (EC 3.5.4.16) type 1	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA2711: GTP cyclohydrolase I (EC 3.5.4.16) type 1	* Escherichia coli str. K-12 substr. MG1655 Site: position = -167 score = 5.29156 sequence = CGATGTTT-(0)-TAACATCT Gene: b2153: GTP cyclohydrolase I (EC 3.5.4.16) type 1	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -10 score = 4.58779 sequence = AGAAACAT-(0)-AAATGTCA Gene: KPN_02591: GTP cyclohydrolase I (EC 3.5.4.16) type 1	Photorhabdus luminescens subsp. laumondii TTO1 Gene: plu1543: GTP cyclohydrolase I (EC 3.5.4.16) type 1	Proteus mirabilis HI4320 Gene: PMI0639: GTP cyclohydrolase I (EC 3.5.4.16) type 1	Salmonella typhimurium LT2 Gene: STM2193: GTP cyclohydrolase I (EC 3.5.4.16) type 1	Serratia proteamaculans 568 Gene: Spro_1560: GTP cyclohydrolase I (EC 3.5.4.16) type 1	Yersinia pestis KIM Gene: y2664: GTP cyclohydrolase I (EC 3.5.4.16) type 1	GTP cyclohydrolase I (EC 3.5.4.16) type 1

CRON 16.
metK	* Citrobacter koseri ATCC BAA-895 Site: position = -144 score = 4.69036 sequence = AGCCATCC-(0)-AGATGTTA Gene: CKO_04317: S-adenosylmethionine synthetase (EC 2.5.1.6)	* Edwardsiella tarda EIB202 Site: position = -209 score = 5.13812 sequence = AGCCGTCC-(0)-AGATGTTA Gene: ETAE_2964: S-adenosylmethionine synthetase (EC 2.5.1.6)	* Enterobacter sp. 638 Site: position = -144 score = 5.89572 sequence = AGACGTCC-(0)-AGATGTTA Gene: Ent638_3346: S-adenosylmethionine synthetase (EC 2.5.1.6)	* Erwinia amylovora ATCC 49946 Site: position = -164 score = 5.89572 sequence = AGACGTCC-(0)-AGATGTTA Gene: EAM_2826: S-adenosylmethionine synthetase (EC 2.5.1.6)	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -71 score = 4.94804 sequence = AGATGTTA-(0)-ATCCGTCT Gene: ECA3920: S-adenosylmethionine synthetase (EC 2.5.1.6)	* Escherichia coli str. K-12 substr. MG1655 Site: position = -145 score = 4.69036 sequence = AGCCATCC-(0)-AGATGTTA Gene: b2942: S-adenosylmethionine synthetase (EC 2.5.1.6)	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -136 score = 4.71731 sequence = AGAAGTTA-(0)-ATCCGTCT Gene: KPN_03375: S-adenosylmethionine synthetase (EC 2.5.1.6)	* Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -64 score = 5.19075 sequence = AGCCATCT-(0)-AGATGTTA Gene: plu3683: S-adenosylmethionine synthetase (EC 2.5.1.6)	* Proteus mirabilis HI4320 Site: position = -60 score = 6.0516 sequence = GGACGTCT-(0)-AGATGTTA Gene: PMI2095: S-adenosylmethionine synthetase (EC 2.5.1.6)	* Salmonella typhimurium LT2 Site: position = -145 score = 5.13812 sequence = AGCCGTCC-(0)-AGATGTTA Gene: STM3090: S-adenosylmethionine synthetase (EC 2.5.1.6)	* Serratia proteamaculans 568 Site: position = -177 score = 5.89572 sequence = AGACGTCC-(0)-AGATGTTA Gene: Spro_3974: S-adenosylmethionine synthetase (EC 2.5.1.6)	* Yersinia pestis KIM Site: position = -288 score = 5.89572 sequence = AGACGTCC-(0)-AGATGTTA Gene: y3314: S-adenosylmethionine synthetase (EC 2.5.1.6)	S-adenosylmethionine synthetase (EC 2.5.1.6)

CRON 17.
btuB	Citrobacter koseri ATCC BAA-895 Gene: CKO_03025: TonB-dependent outer membrane transporter for vitamin B12	Edwardsiella tarda EIB202 Gene: ETAE_3467: TonB-dependent outer membrane transporter for vitamin B12	* Enterobacter sp. 638 Site: position = -270 score = 5.619 sequence = AGCTGTCT-(0)-GGACATCC Gene: Ent638_4020: TonB-dependent outer membrane transporter for vitamin B12	Erwinia amylovora ATCC 49946	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -393 score = 6.09813 sequence = AGAAGTCT-(0)-AGACTTCC Gene: ECA4238: TonB-dependent outer membrane transporter for vitamin B12	* Escherichia coli str. K-12 substr. MG1655 Site: position = -318 score = 4.96421 sequence = AGATGTCC-(0)-AGATCTTG Gene: b3966: TonB-dependent outer membrane transporter for vitamin B12	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -280 score = 5.88866 sequence = AGCAGTCT-(0)-GGACATCT Gene: KPN_04255: TonB-dependent outer membrane transporter for vitamin B12	* Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -245 score = 4.71153 sequence = AAACGGCT-(0)-GACTTTCT Gene: plu4735: TonB-dependent outer membrane transporter for vitamin B12	* Proteus mirabilis HI4320 Site: position = -321 score = 4.92448 sequence = AGATGTCC-(0)-AGTATTCT Gene: PMI3246: TonB-dependent outer membrane transporter for vitamin B12	Salmonella typhimurium LT2 Gene: STM4130: TonB-dependent outer membrane transporter for vitamin B12	* Serratia proteamaculans 568 Site: position = -307 score = 6.23317 sequence = AGCAGTCT-(0)-AGACATCT Gene: Spro_4770: TonB-dependent outer membrane transporter for vitamin B12	* Yersinia pestis KIM Site: position = -357 score = 6.64625 sequence = GGAAGTCT-(0)-AGACATCT Gene: y0325: TonB-dependent outer membrane transporter for vitamin B12	TonB-dependent outer membrane transporter for vitamin B12

CRON 18.
mccA	Citrobacter koseri ATCC BAA-895 Gene: CKO_01706: Cystathionine beta-synthase (EC 4.2.1.22)	Edwardsiella tarda EIB202 Gene: ETAE_1928: Cystathionine beta-synthase (EC 4.2.1.22)	* Enterobacter sp. 638 Site: position = -140 score = 4.7837 sequence = AGCCAGCT-(0)-TAACGGCT Gene: Ent638_1770: Cystathionine beta-synthase (EC 4.2.1.22)	Erwinia amylovora ATCC 49946	Erwinia carotovora subsp. atroseptica SCRI1043	Escherichia coli str. K-12 substr. MG1655	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_03409: Cystathionine beta-synthase (EC 4.2.1.22)	* Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -152 score = 6.41439 sequence = GGAAATCT-(0)-AAACGTCT Gene: plu0524: Cystathionine beta-synthase (EC 4.2.1.22)	Proteus mirabilis HI4320	Salmonella typhimurium LT2	* Serratia proteamaculans 568 Site: position = -170 score = 5.23889 sequence = AAACGGCT-(0)-GCACATCT Gene: Spro_1627: Cystathionine beta-synthase (EC 4.2.1.22)	Yersinia pestis KIM	Cystathionine beta-synthase (EC 4.2.1.22)
mccB	Citrobacter koseri ATCC BAA-895 Gene: CKO_01707: Cystathionine gamma-lyase (EC 4.4.1.1)	Edwardsiella tarda EIB202 Gene: ETAE_1929: Cystathionine gamma-lyase (EC 4.4.1.1)	Enterobacter sp. 638 Gene: Ent638_1769: Cystathionine gamma-lyase (EC 4.4.1.1)	Erwinia amylovora ATCC 49946	Erwinia carotovora subsp. atroseptica SCRI1043	Escherichia coli str. K-12 substr. MG1655	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_03410: Cystathionine gamma-lyase (EC 4.4.1.1)	Photorhabdus luminescens subsp. laumondii TTO1 Gene: plu0523: Cystathionine gamma-lyase (EC 4.4.1.1)	Proteus mirabilis HI4320	Salmonella typhimurium LT2	Serratia proteamaculans 568 Gene: Spro_1626: Cystathionine gamma-lyase (EC 4.4.1.1)	Yersinia pestis KIM	Cystathionine gamma-lyase (EC 4.4.1.1)

CRON 19.
mtnX	Citrobacter koseri ATCC BAA-895 Gene: CKO_03981: Predicted methylthioribose ABC transporter, ATP-binding protein	Edwardsiella tarda EIB202	* Enterobacter sp. 638 Site: position = -116 score = 5.4802 sequence = GGACATCC-(0)-GGATGGCT Gene: Ent638_1135: Predicted methylthioribose ABC transporter, ATP-binding protein	Erwinia amylovora ATCC 49946 Gene: EAM_3425: Predicted methylthioribose ABC transporter, ATP-binding protein	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -82 score = 4.74919 sequence = AGCTGTAT-(0)-TAAATTCT Gene: ECA2719: Predicted methylthioribose ABC transporter, ATP-binding protein	Escherichia coli str. K-12 substr. MG1655	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -119 score = 5.82471 sequence = GGACATCC-(0)-AGATGGCT Gene: KPN_00622: Predicted methylthioribose ABC transporter, ATP-binding protein	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2	* Serratia proteamaculans 568 Site: position = -28 score = 6.1379 sequence = AAACACCT-(0)-AAACGTCT Gene: Spro_3218: Predicted methylthioribose ABC transporter, ATP-binding protein	Yersinia pestis KIM	Predicted methylthioribose ABC transporter, ATP-binding protein
mtnY	Citrobacter koseri ATCC BAA-895 Gene: CKO_03980: Predicted methylthioribose ABC transporter, permease protein	Edwardsiella tarda EIB202	Enterobacter sp. 638 Gene: Ent638_1136: Predicted methylthioribose ABC transporter, permease protein	Erwinia amylovora ATCC 49946 Gene: EAM_3424: Predicted methylthioribose ABC transporter, permease protein	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA2720: Predicted methylthioribose ABC transporter, permease protein	Escherichia coli str. K-12 substr. MG1655	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_00623: Predicted methylthioribose ABC transporter, permease protein	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2	Serratia proteamaculans 568 Gene: Spro_3219: Predicted methylthioribose ABC transporter, permease protein	Yersinia pestis KIM Gene: y2615: Predicted methylthioribose ABC transporter, permease protein	Predicted methylthioribose ABC transporter, permease protein
mtnZ	Citrobacter koseri ATCC BAA-895 Gene: CKO_03979: Predicted methylthioribose ABC transporter, substrate-binding protein	Edwardsiella tarda EIB202	Enterobacter sp. 638 Gene: Ent638_1137: Predicted methylthioribose ABC transporter, substrate-binding protein	Erwinia amylovora ATCC 49946 Gene: EAM_3423: Predicted methylthioribose ABC transporter, substrate-binding protein	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -100 score = 5.10036 sequence = AGACATCC-(0)-AGACATAA Gene: ECA1405: Predicted methylthioribose ABC transporter, substrate-binding protein	Escherichia coli str. K-12 substr. MG1655	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_00624: Predicted methylthioribose ABC transporter, substrate-binding protein	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2	Serratia proteamaculans 568 Gene: Spro_2370: Predicted methylthioribose ABC transporter, substrate-binding protein	* Yersinia pestis KIM Site: position = -124 score = 5.04899 sequence = GGACGTCT-(0)-AGAAGCAA Gene: y2651: Predicted methylthioribose ABC transporter, substrate-binding protein	Predicted methylthioribose ABC transporter, substrate-binding protein
COG5276	Citrobacter koseri ATCC BAA-895 Gene: CKO_03976: Hypothetical protein, COG5276 family	Edwardsiella tarda EIB202	Enterobacter sp. 638 Gene: Ent638_1138: Hypothetical protein, COG5276 family	Erwinia amylovora ATCC 49946	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA1404: Hypothetical protein, COG5276 family	Escherichia coli str. K-12 substr. MG1655	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_00625: Hypothetical protein, COG5276 family	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2	Serratia proteamaculans 568 Gene: Spro_2369: Hypothetical protein, COG5276 family	Yersinia pestis KIM Gene: y2652: Hypothetical protein, COG5276 family	Hypothetical protein, COG5276 family
CKO_03982	* Citrobacter koseri ATCC BAA-895 Site: position = 11 score = 6.3251 sequence = AGACATCT-(0)-GGATGGCT Gene: CKO_03982: hypothetical protein	Edwardsiella tarda EIB202	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Erwinia carotovora subsp. atroseptica SCRI1043	Escherichia coli str. K-12 substr. MG1655	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2	Serratia proteamaculans 568	Yersinia pestis KIM	hypothetical protein

CRON 20.
mtnE	* Citrobacter koseri ATCC BAA-895 Site: position = -75 score = 6.84497 sequence = AGACGTCT-(0)-AAGCGTCT Gene: CKO_02559: Methionine aminotransferase	Edwardsiella tarda EIB202	* Enterobacter sp. 638 Site: position = -83 score = 6.84497 sequence = AGACGTCT-(0)-AAGCGTCT Gene: Ent638_1144: Methionine aminotransferase	Erwinia amylovora ATCC 49946 Gene: EAM_0882: Methionine aminotransferase	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -83 score = 6.11272 sequence = AAACGTCC-(0)-AAGCGTCT Gene: ECA3488: Methionine aminotransferase	* Escherichia coli str. K-12 substr. MG1655 Site: position = -82 score = 7.11573 sequence = AGACATCT-(0)-AAACGTCT Gene: b0600: Methionine aminotransferase	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -83 score = 6.84497 sequence = AGACGTCT-(0)-AAGCGTCT Gene: KPN_00645: Methionine aminotransferase	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	* Salmonella typhimurium LT2 Site: position = -83 score = 7.11573 sequence = AGACATCT-(0)-AAACGTCT Gene: STM0603: Methionine aminotransferase	* Serratia proteamaculans 568 Site: position = -82 score = 5.63961 sequence = AGCCATCT-(0)-AAGCGTCT Gene: Spro_0941: Methionine aminotransferase	Yersinia pestis KIM	Methionine aminotransferase

CRON 21.
metC	2 Citrobacter koseri ATCC BAA-895* Site: position = 44 score = 6.58406 sequence = AGACATCC-(0)-AGACGTAT Gene: CKO_04402: Cystathionine beta-lyase (EC 4.4.1.8) Gene: CKO_03454: Cystathionine beta-lyase (EC 4.4.1.8)	Edwardsiella tarda EIB202 Gene: ETAE_1055: Cystathionine beta-lyase (EC 4.4.1.8)	* Enterobacter sp. 638 Site: position = -34 score = 6.13542 sequence = GGACGTCC-(0)-AGACGGAT Gene: Ent638_3418: Cystathionine beta-lyase (EC 4.4.1.8)	Erwinia amylovora ATCC 49946 Gene: EAM_2957: Cystathionine beta-lyase (EC 4.4.1.8)	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA0354: Cystathionine beta-lyase (EC 4.4.1.8)	* Escherichia coli str. K-12 substr. MG1655 Site: position = -34 score = 6.58406 sequence = AGACATCC-(0)-AGACGTAT Gene: b3008: Cystathionine beta-lyase (EC 4.4.1.8)	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -34 score = 7.03183 sequence = AGACGTCC-(0)-AGACGTAT Gene: KPN_03428: Cystathionine beta-lyase (EC 4.4.1.8)	Photorhabdus luminescens subsp. laumondii TTO1 Gene: plu3942: Cystathionine beta-lyase (EC 4.4.1.8)	2 Proteus mirabilis HI4320 Gene: PMI0028: Cystathionine beta-lyase (EC 4.4.1.8) Gene: PMI0626: Cystathionine beta-lyase (EC 4.4.1.8)	* Salmonella typhimurium LT2 Site: position = -34 score = 6.05808 sequence = AGACATCC-(0)-AGACGGTT Gene: STM3161: Cystathionine beta-lyase (EC 4.4.1.8)	* Serratia proteamaculans 568 Site: position = -89 score = 6.54101 sequence = AAACGTCT-(0)-GGATGGCT Gene: Spro_4212: Cystathionine beta-lyase (EC 4.4.1.8)	Yersinia pestis KIM Gene: y3496: Cystathionine beta-lyase (EC 4.4.1.8)	Cystathionine beta-lyase (EC 4.4.1.8)

CRON 22.
metB	* Citrobacter koseri ATCC BAA-895 Site: position = -78 score = 6.93549 sequence = AGATGTAT-(0)-TGACGTCT Gene: CKO_03055: Cystathionine gamma-synthase (EC 2.5.1.48)	* Edwardsiella tarda EIB202 Site: position = -74 score = 6.93549 sequence = AGATGTAT-(0)-TGACGTCT Gene: ETAE_3430: Cystathionine gamma-synthase (EC 2.5.1.48)	* Enterobacter sp. 638 Site: position = -85 score = 6.77967 sequence = AGATGTCC-(0)-AGATGTAT Gene: Ent638_4035: Cystathionine gamma-synthase (EC 2.5.1.48)	* Erwinia amylovora ATCC 49946 Site: position = -74 score = 6.93549 sequence = AGATGTAT-(0)-TGACGTCT Gene: EAM_0133: Cystathionine gamma-synthase (EC 2.5.1.48)	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -92 score = 7.07523 sequence = AGAAGTTT-(0)-AGATGTCT Gene: ECA4252: Cystathionine gamma-synthase (EC 2.5.1.48)	* Escherichia coli str. K-12 substr. MG1655 Site: position = -87 score = 6.77967 sequence = AGATGTCC-(0)-AGATGTAT Gene: b3939: Cystathionine gamma-synthase (EC 2.5.1.48)	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -78 score = 6.93549 sequence = AGATGTAT-(0)-TGACGTCT Gene: KPN_04233: Cystathionine gamma-synthase (EC 2.5.1.48)	* Photorhabdus luminescens subsp. laumondii TTO1 Site: position = -69 score = 6.97815 sequence = AGATGTCT-(0)-AGATGTGT Gene: plu4756: Cystathionine gamma-synthase (EC 2.5.1.48)	* Proteus mirabilis HI4320 Site: position = -86 score = 7.28006 sequence = AGATGTCT-(0)-AGATGTAT Gene: PMI3223: Cystathionine gamma-synthase (EC 2.5.1.48)	* Salmonella typhimurium LT2 Site: position = -76 score = 6.93549 sequence = AGATGTAT-(0)-TGACGTCT Gene: STM4100: Cystathionine gamma-synthase (EC 2.5.1.48)	* Serratia proteamaculans 568 Site: position = -85 score = 6.77967 sequence = AGATGTCC-(0)-AGATGTAT Gene: Spro_4786: Cystathionine gamma-synthase (EC 2.5.1.48)	Yersinia pestis KIM	Cystathionine gamma-synthase (EC 2.5.1.48)
metL	Citrobacter koseri ATCC BAA-895 Gene: CKO_03054: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Edwardsiella tarda EIB202 Gene: ETAE_3429: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Enterobacter sp. 638 Gene: Ent638_4034: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Erwinia amylovora ATCC 49946 Gene: EAM_0134: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA4251: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Escherichia coli str. K-12 substr. MG1655 Gene: b3940: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_04234: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Photorhabdus luminescens subsp. laumondii TTO1 Gene: plu4755: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Proteus mirabilis HI4320 Gene: PMI3224: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Salmonella typhimurium LT2 Gene: STM4101: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Serratia proteamaculans 568 Gene: Spro_4785: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	* Yersinia pestis KIM Site: position = -1245 score = 6.77967 sequence = AGATGTCC-(0)-AGATGTAT Gene: y0303: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)	Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog MetJ - Enterobacteriales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --