Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of MetJ in Proteus mirabilis HI4320

Properties
Regulator type: Transcription factor
TF locus tag: PMI3222
Regulator family: MetJ
Regulation mode: repressor
Biological process: Methionine metabolism; Methionine biosynthesis
Effector: S-adenosylmethionine
Regulog: MetJ - Enterobacteriales
Statistics of regulated genes:
- Genes 13
- Operons 10
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 167 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -135
Score: 7.4
Sequence: AAACGTCT-(0)-AGATGTCT
Locus tag: PMI3020
Name: metQ2
Funciton: Methionine ABC transporter substrate-binding protein
metQ2
Methionine ABC transporter substrate-binding protein

Position: -215
Score: 6.2
Sequence: ATACATCT-(0)-AGACATCT
Locus tag: PMI3222
Name: metJ
Funciton: S-adenosylmethionine-responsive transcriptional repressor MetJ
metJ
S-adenosylmethionine-responsive transcriptional repressor MetJ

Position: -35
Score: 6.6
Sequence: AAACATCT-(0)-AGACGGCT
Locus tag: PMI3529
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

Position: -33
Score: 7.3
Sequence: AGATGTCT-(0)-AGATGTTT
Locus tag: PMI2765
Name: metA
Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
metA
Homoserine O-succinyltransferase (EC 2.3.1.46)

Position: -82
Score: 6.7
Sequence: GGACGTCT-(0)-AGACGCCT
Locus tag: PMI2259
Name: metN
Funciton: Methionine ABC transporter ATP-binding protein
Locus tag: PMI2260
Name: metI
Funciton: Methionine ABC transporter permease protein
Locus tag: PMI2261
Name: metQ
Funciton: Methionine ABC transporter substrate-binding protein
metN
Methionine ABC transporter ATP-binding protein
metI
Methionine ABC transporter permease protein
metQ
Methionine ABC transporter substrate-binding protein

Position: -88
Score: 6.7
Sequence: AGCCGTCT-(0)-AGATGTTT
Locus tag: PMI3528
Name: metR
Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
metR
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family

Position: -86
Score: 7.3
Sequence: AGATGTCT-(0)-AGATGTAT
Locus tag: PMI3223
Name: metB
Funciton: Cystathionine gamma-synthase (EC 2.5.1.48)
Locus tag: PMI3224
Name: metL
Funciton: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
metB
Cystathionine gamma-synthase (EC 2.5.1.48)
metL
Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)

Position: -92
Score: 6.6
Sequence: AGACGTCT-(0)-AAATGGTT
Locus tag: PMI2932
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
metF
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)

Position: -321
Score: 4.9
Sequence: AGATGTCC-(0)-AGTATTCT
Locus tag: PMI3246
Name: btuB
Funciton: TonB-dependent outer membrane transporter for vitamin B12
btuB
TonB-dependent outer membrane transporter for vitamin B12

Position: -60
Score: 6.1
Sequence: GGACGTCT-(0)-AGATGTTA
Locus tag: PMI2095
Name: metK
Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
metK
S-adenosylmethionine synthetase (EC 2.5.1.6)
Export
Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD