Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of MetJ in Salmonella typhimurium LT2

Properties
Regulator type: Transcription factor
TF locus tag: STM4099
Regulator family: MetJ
Regulation mode: repressor
Biological process: Methionine metabolism; Methionine biosynthesis
Effector: S-adenosylmethionine
Regulog: MetJ - Enterobacteriales
Statistics of regulated genes:
- Genes 16
- Operons 12
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 167 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -59
Score: 7.4
Sequence: AGACGTTT-(0)-AGATGTCT
Locus tag: STM0602
Name: ybdH
Funciton: Uncharacterized oxidoreductase YbdH
ybdH
Uncharacterized oxidoreductase YbdH

Position: -188
Score: 5.9
Sequence: GGACATCT-(0)-AAACTTCT
Locus tag: STM4099
Name: metJ
Funciton: S-adenosylmethionine-responsive transcriptional repressor MetJ
metJ
S-adenosylmethionine-responsive transcriptional repressor MetJ

Position: -10
Score: 6.2
Sequence: GGAAGTAT-(0)-AGATGTCC
Locus tag: STM0608
Name: ahpC
Funciton: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)
Locus tag: STM0609
Name: ahpF
Funciton: Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)
ahpC
Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)
ahpF
Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)

Position: -43
Score: 6.9
Sequence: GGATGTCT-(0)-AAACGTTT
Locus tag: STM4182
Name: metA
Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
metA
Homoserine O-succinyltransferase (EC 2.3.1.46)

Position: -99
Score: 6.6
Sequence: AGACGTCT-(0)-GGATGCCT
Locus tag: STM0247
Name: metN
Funciton: Methionine ABC transporter ATP-binding protein
Locus tag: STM0246
Name: metI
Funciton: Methionine ABC transporter permease protein
Locus tag: STM0245
Name: metQ
Funciton: Methionine ABC transporter substrate-binding protein
metN
Methionine ABC transporter ATP-binding protein
metI
Methionine ABC transporter permease protein
metQ
Methionine ABC transporter substrate-binding protein

Position: -87
Score: 7.1
Sequence: AGACGTCT-(0)-GGATGTTT
Locus tag: STM3964
Name: metR
Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
metR
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family

Position: -76
Score: 6.9
Sequence: AGATGTAT-(0)-TGACGTCT
Locus tag: STM4100
Name: metB
Funciton: Cystathionine gamma-synthase (EC 2.5.1.48)
Locus tag: STM4101
Name: metL
Funciton: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
metB
Cystathionine gamma-synthase (EC 2.5.1.48)
metL
Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)

Position: -65
Score: 6.4
Sequence: GGACGTCT-(0)-AAACGGAT
Locus tag: STM4105
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
metF
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)

Position: -177
Score: 6.6
Sequence: AAACATCC-(0)-AGACGTCT
Locus tag: STM3965
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

Position: -34
Score: 6.1
Sequence: AGACATCC-(0)-AGACGGTT
Locus tag: STM3161
Name: metC
Funciton: Cystathionine beta-lyase (EC 4.4.1.8)
metC
Cystathionine beta-lyase (EC 4.4.1.8)

Position: -83
Score: 7.1
Sequence: AGACATCT-(0)-AAACGTCT
Locus tag: STM0603
Name: mtnE
Funciton: Methionine aminotransferase
mtnE
Methionine aminotransferase

Position: -145
Score: 5.1
Sequence: AGCCGTCC-(0)-AGATGTTA
Locus tag: STM3090
Name: metK
Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
metK
S-adenosylmethionine synthetase (EC 2.5.1.6)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD