Regulon of MetJ in Klebsiella pneumoniae subsp. pneumoniae MGH 78578
| Regulator type: | Transcription factor |
| TF locus tag: | KPN_04232 |
| Regulator family: | MetJ |
| Regulation mode: | repressor |
| Biological process: | Methionine metabolism; Methionine biosynthesis |
| Effector: | S-adenosylmethionine |
| Regulog: | MetJ - Enterobacteriales |
| Statistics of regulated genes: | |
| - Genes | 29 |
| - Operons | 20 |
| Visualization: | |
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Allows to visualize regulon content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Enterobacteriales
- By trascription factor - MetJ
- By TF family - MetJ
- By effector - S-adenosylmethionine
- By pathway - Methionine metabolism
- By pathway - Methionine biosynthesis
| Locus Tag | Name | Function | |
|---|---|---|---|
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Position: -10
Score: 4.6 Sequence: AGAAACAT-(0)-AAATGTCA
Locus tag: KPN_02591
Name: folE Funciton: GTP cyclohydrolase I (EC 3.5.4.16) type 1 |
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folE
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GTP cyclohydrolase I (EC 3.5.4.16) type 1
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Position: -78
Score: 5.7 Sequence: AGCCATCC-(0)-AGAAGTCT
Locus tag: KPN_01615
Name: metE2 Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14) |
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metE2
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Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
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Position: -189
Score: 5.9 Sequence: GGACATCT-(0)-AAACTTCT
Locus tag: KPN_04232
Name: metJ Funciton: S-adenosylmethionine-responsive transcriptional repressor MetJ |
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metJ
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S-adenosylmethionine-responsive transcriptional repressor MetJ
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Position: -69
Score: 7 Sequence: GGATGTTT-(0)-AGATGTCT
Locus tag: KPN_00309
Name: mmuP Funciton: S-methylmethionine transporter
Locus tag: KPN_00310
Name: mmuM Funciton: Homocysteine S-methyltransferase (EC 2.1.1.10) |
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mmuP
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S-methylmethionine transporter
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mmuM
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Homocysteine S-methyltransferase (EC 2.1.1.10)
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Position: -76
Score: 6.3 Sequence: AGCCGTTC-(0)-AGACGTCT
Locus tag: KPN_00627
Name: mtnA Funciton: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23) |
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mtnA
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Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)
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Position: -10
Score: 6.2 Sequence: GGAAGTAT-(0)-AGATGTCC
Locus tag: KPN_00650
Name: ahpC Funciton: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)
Locus tag: KPN_00651
Name: ahpF Funciton: Alkyl hydroperoxide reductase protein F (EC 1.6.4.-) |
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ahpC
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Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)
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ahpF
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Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)
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Position: -47
Score: 5.8 Sequence: AGCCATTT-(0)-AGACGGCT
Locus tag: KPN_00634
Name: mtnB Funciton: Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109) |
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mtnB
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Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)
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Position: -43
Score: 6.9 Sequence: GGATGTCT-(0)-AAACGTTT
Locus tag: KPN_04394
Name: metA Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46) |
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metA
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Homoserine O-succinyltransferase (EC 2.3.1.46)
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Position: -49
Score: 7.2 Sequence: AGAAGTAT-(0)-AGACGTCT
Locus tag: KPN_00626
Name: mtnK Funciton: 5-methylthioribose kinase (EC 2.7.1.100) |
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mtnK
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5-methylthioribose kinase (EC 2.7.1.100)
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Position: -100
Score: 6.6 Sequence: AGACGTCT-(0)-GGATGCCT
Locus tag: KPN_00213
Name: metN Funciton: Methionine ABC transporter ATP-binding protein
Locus tag: KPN_00212
Name: metI Funciton: Methionine ABC transporter permease protein
Locus tag: KPN_00211
Name: metQ Funciton: Methionine ABC transporter substrate-binding protein |
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metN
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Methionine ABC transporter ATP-binding protein
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metI
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Methionine ABC transporter permease protein
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metQ
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Methionine ABC transporter substrate-binding protein
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Position: -87
Score: 6.9 Sequence: AGACGTCC-(0)-AGATGTTT
Locus tag: KPN_04324
Name: metR Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family |
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metR
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Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
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Position: -78
Score: 6.9 Sequence: AGATGTAT-(0)-TGACGTCT
Locus tag: KPN_04233
Name: metB Funciton: Cystathionine gamma-synthase (EC 2.5.1.48)
Locus tag: KPN_04234
Name: metL Funciton: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3) |
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metB
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Cystathionine gamma-synthase (EC 2.5.1.48)
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metL
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Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
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Position: -64
Score: 7 Sequence: GGACGTCT-(0)-AAACGTAT
Locus tag: KPN_04239
Name: metF Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) |
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metF
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5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
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Position: -176
Score: 6.8 Sequence: AAACATCT-(0)-GGACGTCT
Locus tag: KPN_04325
Name: metE Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14) |
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metE
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5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
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Position: -59
Score: 6.8 Sequence: AGACGCTT-(0)-AGACGTCT
Locus tag: KPN_00644
Name: mtnC Funciton: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)
Locus tag: KPN_00643
Name: mtnD Funciton: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54) |
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mtnC
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2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)
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mtnD
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1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)
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Position: -34
Score: 7 Sequence: AGACGTCC-(0)-AGACGTAT
Locus tag: KPN_03428
Name: metC Funciton: Cystathionine beta-lyase (EC 4.4.1.8) |
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metC
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Cystathionine beta-lyase (EC 4.4.1.8)
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Position: -83
Score: 6.8 Sequence: AGACGTCT-(0)-AAGCGTCT
Locus tag: KPN_00645
Name: mtnE Funciton: Methionine aminotransferase |
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mtnE
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Methionine aminotransferase
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Position: -119
Score: 5.8 Sequence: GGACATCC-(0)-AGATGGCT
Locus tag: KPN_00622
Name: mtnX Funciton: Predicted methylthioribose ABC transporter, ATP-binding protein
Locus tag: KPN_00623
Name: mtnY Funciton: Predicted methylthioribose ABC transporter, permease protein
Locus tag: KPN_00624
Name: mtnZ Funciton: Predicted methylthioribose ABC transporter, substrate-binding protein
Locus tag: KPN_00625
Name: COG5276 Funciton: Hypothetical protein, COG5276 family |
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mtnX
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Predicted methylthioribose ABC transporter, ATP-binding protein
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mtnY
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Predicted methylthioribose ABC transporter, permease protein
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mtnZ
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Predicted methylthioribose ABC transporter, substrate-binding protein
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COG5276
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Hypothetical protein, COG5276 family
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Position: -280
Score: 5.9 Sequence: AGCAGTCT-(0)-GGACATCT
Locus tag: KPN_04255
Name: btuB Funciton: TonB-dependent outer membrane transporter for vitamin B12 |
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btuB
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TonB-dependent outer membrane transporter for vitamin B12
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Position: -136
Score: 4.7 Sequence: AGAAGTTA-(0)-ATCCGTCT
Locus tag: KPN_03375
Name: metK Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6) |
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metK
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S-adenosylmethionine synthetase (EC 2.5.1.6)
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |