Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of MetJ in Erwinia carotovora subsp. atroseptica SCRI1043

Properties
Regulator type: Transcription factor
TF locus tag: ECA4253
Regulator family: MetJ
Regulation mode: repressor
Biological process: Methionine metabolism; Methionine biosynthesis
Effector: S-adenosylmethionine
Regulog: MetJ - Enterobacteriales
Statistics of regulated genes:
- Genes 25
- Operons 17
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 167 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -126
Score: 6.6
Sequence: AGACGTCC-(0)-AGATGGCT
Locus tag: ECA1113
Name: metE2
Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
ECA1113
metE2
Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
Position: -87
Score: 6.9
Sequence: GGAAGTCT-(0)-AAACGTCT
Locus tag: ECA2798
Name: mmuP
Funciton: S-methylmethionine transporter
Locus tag: ECA2797
Name: mmuM
Funciton: Homocysteine S-methyltransferase (EC 2.1.1.10)
ECA2798
mmuP
S-methylmethionine transporter
ECA2797
mmuM
Homocysteine S-methyltransferase (EC 2.1.1.10)
Position: -77
Score: 6.5
Sequence: AAACGTTC-(0)-GGACGTCT
Locus tag: ECA3477
Name: mtnA
Funciton: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)
ECA3477
mtnA
Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)
Position: -105
Score: 6.3
Sequence: GGACGTTT-(0)-AAATGGCT
Locus tag: ECA3487
Name: mtnB
Funciton: Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)
Locus tag: ECA3486
Name: mtnC
Funciton: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)
Locus tag: ECA3485
Name: mtnD
Funciton: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)
ECA3487
mtnB
Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)
ECA3486
mtnC
2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)
ECA3485
mtnD
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)
Position: -110
Score: 6.3
Sequence: AGACATCT-(0)-AAACTTCT
Locus tag: ECA4253
Name: metJ
Funciton: S-adenosylmethionine-responsive transcriptional repressor MetJ
ECA4253
metJ
S-adenosylmethionine-responsive transcriptional repressor MetJ
Position: -32
Score: 6.2
Sequence: AAACATCT-(0)-GGACGGCT
Locus tag: ECA0181
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
ECA0181
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Position: -43
Score: 6.9
Sequence: GGATGTCT-(0)-AAACGTTT
Locus tag: ECA3992
Name: metA
Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
ECA3992
metA
Homoserine O-succinyltransferase (EC 2.3.1.46)
Position: -65
Score: 6.9
Sequence: AGATGTAT-(0)-AGACGTCC
Locus tag: ECA3476
Name: mtnK
Funciton: 5-methylthioribose kinase (EC 2.7.1.100)
ECA3476
mtnK
5-methylthioribose kinase (EC 2.7.1.100)
Position: -87
Score: 5.8
Sequence: AGCCGTCT-(0)-AGACGCCC
Locus tag: ECA3524
Name: metN
Funciton: Methionine ABC transporter ATP-binding protein
Locus tag: ECA3525
Name: metI
Funciton: Methionine ABC transporter permease protein
Locus tag: ECA3526
Name: metQ
Funciton: Methionine ABC transporter substrate-binding protein
ECA3524
metN
Methionine ABC transporter ATP-binding protein
ECA3525
metI
Methionine ABC transporter permease protein
ECA3526
metQ
Methionine ABC transporter substrate-binding protein
Position: -88
Score: 6.2
Sequence: AGCCGTCC-(0)-AGATGTTT
Locus tag: ECA0180
Name: metR
Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
ECA0180
metR
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
Position: -92
Score: 7.1
Sequence: AGAAGTTT-(0)-AGATGTCT
Locus tag: ECA4252
Name: metB
Funciton: Cystathionine gamma-synthase (EC 2.5.1.48)
Locus tag: ECA4251
Name: metL
Funciton: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
ECA4252
metB
Cystathionine gamma-synthase (EC 2.5.1.48)
ECA4251
metL
Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
Position: -65
Score: 7.3
Sequence: AGACGTCT-(0)-AAACGTAT
Locus tag: ECA4244
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
ECA4244
metF
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Position: -82
Score: 4.7
Sequence: AGCTGTAT-(0)-TAAATTCT
Locus tag: ECA2719
Name: mtnX
Funciton: Predicted methylthioribose ABC transporter, ATP-binding protein
Locus tag: ECA2720
Name: mtnY
Funciton: Predicted methylthioribose ABC transporter, permease protein
ECA2719
mtnX
Predicted methylthioribose ABC transporter, ATP-binding protein
ECA2720
mtnY
Predicted methylthioribose ABC transporter, permease protein
Position: -100
Score: 5.1
Sequence: AGACATCC-(0)-AGACATAA
Locus tag: ECA1405
Name: mtnZ
Funciton: Predicted methylthioribose ABC transporter, substrate-binding protein
Locus tag: ECA1404
Name: COG5276
Funciton: Hypothetical protein, COG5276 family
ECA1405
mtnZ
Predicted methylthioribose ABC transporter, substrate-binding protein
ECA1404
COG5276
Hypothetical protein, COG5276 family
Position: -393
Score: 6.1
Sequence: AGAAGTCT-(0)-AGACTTCC
Locus tag: ECA4238
Name: btuB
Funciton: TonB-dependent outer membrane transporter for vitamin B12
ECA4238
btuB
TonB-dependent outer membrane transporter for vitamin B12
Position: -71
Score: 4.9
Sequence: AGATGTTA-(0)-ATCCGTCT
Locus tag: ECA3920
Name: metK
Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
ECA3920
metK
S-adenosylmethionine synthetase (EC 2.5.1.6)
Position: -83
Score: 6.1
Sequence: AAACGTCC-(0)-AAGCGTCT
Locus tag: ECA3488
Name: mtnE
Funciton: Methionine aminotransferase
ECA3488
mtnE
Methionine aminotransferase
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