Regulon of MetJ in Erwinia amylovora ATCC 49946

Properties
Regulator type:	Transcription factor
TF locus tag:	EAM_0132
Regulator family:	MetJ
Regulation mode:	repressor
Biological process:	Methionine metabolism; Methionine biosynthesis
Effector:	S-adenosylmethionine
Regulog:	MetJ - Enterobacteriales
Statistics of regulated genes:
- Genes	17
- Operons	12
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 167 sites [see more]

Member of regulog collections

By taxonomy - Enterobacteriales
By trascription factor - MetJ
By TF family - MetJ
By effector - S-adenosylmethionine
By pathway - Methionine metabolism
By pathway - Methionine biosynthesis

Regulated operons
	Locus Tag	Name	Function
Position: -84 Score: 6.9 Sequence: AGACGTCC-(0)-AGAAGTCT Locus tag: EAM_0952 Name: metE2 Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
	EAM_0952	metE2	Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
Position: -75 Score: 6.3 Sequence: AGCCGTTC-(0)-AGACGTCT Locus tag: EAM_0888 Name: mtnA Funciton: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)
	EAM_0888	mtnA	Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)
Position: -169 Score: 6.3 Sequence: GGACTTCT-(0)-AAATGTCT Locus tag: EAM_0132 Name: metJ Funciton: S-adenosylmethionine-responsive transcriptional repressor MetJ
	EAM_0132	metJ	S-adenosylmethionine-responsive transcriptional repressor MetJ
Position: -75 Score: 6.8 Sequence: AGACGCTT-(0)-AGACGTCT Locus tag: EAM_0885 Name: mtnB Funciton: Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109) Locus tag: EAM_0886 Name: mtnC Funciton: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77) Locus tag: EAM_0887 Name: mtnD Funciton: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)
	EAM_0885	mtnB	Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)
	EAM_0886	mtnC	2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)
	EAM_0887	mtnD	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)
Position: -78 Score: 6.3 Sequence: AAACATCT-(0)-GGACGTCC Locus tag: EAM_0198 Name: metE Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
	EAM_0198	metE	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Position: -42 Score: 6.8 Sequence: GGATGTCT-(0)-AAACGTAT Locus tag: EAM_0250 Name: metA Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
	EAM_0250	metA	Homoserine O-succinyltransferase (EC 2.3.1.46)
Position: -64 Score: 7.1 Sequence: GGATGTAT-(0)-AGACGTCT Locus tag: EAM_0889 Name: mtnK Funciton: 5-methylthioribose kinase (EC 2.7.1.100)
	EAM_0889	mtnK	5-methylthioribose kinase (EC 2.7.1.100)
Position: -100 Score: 6.6 Sequence: AGACGTCT-(0)-GGATGCCT Locus tag: EAM_0849 Name: metN Funciton: Methionine ABC transporter ATP-binding protein Locus tag: EAM_0848 Name: metI Funciton: Methionine ABC transporter permease protein Locus tag: EAM_0847 Name: metQ Funciton: Methionine ABC transporter substrate-binding protein
	EAM_0849	metN	Methionine ABC transporter ATP-binding protein
	EAM_0848	metI	Methionine ABC transporter permease protein
	EAM_0847	metQ	Methionine ABC transporter substrate-binding protein
Position: -88 Score: 6.6 Sequence: GGACGTCC-(0)-AGATGTTT Locus tag: EAM_0197 Name: metR Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
	EAM_0197	metR	Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
Position: -74 Score: 6.9 Sequence: AGATGTAT-(0)-TGACGTCT Locus tag: EAM_0133 Name: metB Funciton: Cystathionine gamma-synthase (EC 2.5.1.48) Locus tag: EAM_0134 Name: metL Funciton: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
	EAM_0133	metB	Cystathionine gamma-synthase (EC 2.5.1.48)
	EAM_0134	metL	Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
Position: -61 Score: 6.7 Sequence: GAATGTCT-(0)-GGACGTCT Locus tag: EAM_0135 Name: metF Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
	EAM_0135	metF	5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Position: -164 Score: 5.9 Sequence: AGACGTCC-(0)-AGATGTTA Locus tag: EAM_2826 Name: metK Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
	EAM_2826	metK	S-adenosylmethionine synthetase (EC 2.5.1.6)

Export
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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of MetJ in Erwinia amylovora ATCC 49946

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --