Regulon of MetJ in Escherichia coli str. K-12 substr. MG1655

Properties
Regulator type:	Transcription factor
TF locus tag:	b3938
Regulator family:	MetJ
Regulation mode:	repressor
Biological process:	Methionine metabolism; Methionine biosynthesis
Effector:	S-adenosylmethionine
Regulog:	MetJ - Enterobacteriales
Statistics of regulated genes:
- Genes	20
- Operons	15
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 167 sites [see more]

Member of regulog collections

By taxonomy - Enterobacteriales
By trascription factor - MetJ
By TF family - MetJ
By effector - S-adenosylmethionine
By pathway - Methionine metabolism
By pathway - Methionine biosynthesis

Regulated operons
	Locus Tag	Name	Function
Position: -145 Score: 4.7 Sequence: AGCCATCC-(0)-AGATGTTA Locus tag: b2942 Name: metK Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
	b2942	metK	S-adenosylmethionine synthetase (EC 2.5.1.6)
Position: -167 Score: 5.3 Sequence: CGATGTTT-(0)-TAACATCT Locus tag: b2153 Name: folE Funciton: GTP cyclohydrolase I (EC 3.5.4.16) type 1
	b2153	folE	GTP cyclohydrolase I (EC 3.5.4.16) type 1
Position: -42 Score: 7.4 Sequence: AGACGTTT-(0)-AGATGTCT Locus tag: b0599 Name: ybdH Funciton: Uncharacterized oxidoreductase YbdH
	b0599	ybdH	Uncharacterized oxidoreductase YbdH
Position: -34 Score: 6.5 Sequence: GGATGTTT-(0)-AGATGTCC Locus tag: b0260 Name: mmuP Funciton: S-methylmethionine transporter Locus tag: b0261 Name: mmuM Funciton: Homocysteine S-methyltransferase (EC 2.1.1.10)
	b0260	mmuP	S-methylmethionine transporter
	b0261	mmuM	Homocysteine S-methyltransferase (EC 2.1.1.10)
Position: -10 Score: 6.2 Sequence: GGAAGTAT-(0)-AGATGTCC Locus tag: b0605 Name: ahpC Funciton: Alkyl hydroperoxide reductase protein C (EC 1.6.4.-) Locus tag: b0606 Name: ahpF Funciton: Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)
	b0605	ahpC	Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)
	b0606	ahpF	Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)
Position: -43 Score: 6.8 Sequence: GGATGTCT-(0)-AAACGTAT Locus tag: b4013 Name: metA Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
	b4013	metA	Homoserine O-succinyltransferase (EC 2.3.1.46)
Position: -197 Score: 5.9 Sequence: GGACATCT-(0)-AAACTTCT Locus tag: b3938 Name: metJ Funciton: S-adenosylmethionine-responsive transcriptional repressor MetJ
	b3938	metJ	S-adenosylmethionine-responsive transcriptional repressor MetJ
Position: -87 Score: 6.8 Sequence: AGATGTCC-(0)-AGATGTAT Locus tag: b3939 Name: metB Funciton: Cystathionine gamma-synthase (EC 2.5.1.48) Locus tag: b3940 Name: metL Funciton: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
	b3939	metB	Cystathionine gamma-synthase (EC 2.5.1.48)
	b3940	metL	Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
Position: -98 Score: 6.6 Sequence: AGACGTCT-(0)-GGATGCCT Locus tag: b0199 Name: metN Funciton: Methionine ABC transporter ATP-binding protein Locus tag: b0198 Name: metI Funciton: Methionine ABC transporter permease protein Locus tag: b0197 Name: metQ Funciton: Methionine ABC transporter substrate-binding protein
	b0199	metN	Methionine ABC transporter ATP-binding protein
	b0198	metI	Methionine ABC transporter permease protein
	b0197	metQ	Methionine ABC transporter substrate-binding protein
Position: -87 Score: 6.2 Sequence: AGCCGTCC-(0)-AGATGTTT Locus tag: b3828 Name: metR Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
	b3828	metR	Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
Position: -65 Score: 6.4 Sequence: GGACGTCT-(0)-AAACGGAT Locus tag: b3941 Name: metF Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
	b3941	metF	5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Position: -165 Score: 6.2 Sequence: AAACATCT-(0)-GGACGGCT Locus tag: b3829 Name: metE Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
	b3829	metE	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Position: -34 Score: 6.6 Sequence: AGACATCC-(0)-AGACGTAT Locus tag: b3008 Name: metC Funciton: Cystathionine beta-lyase (EC 4.4.1.8)
	b3008	metC	Cystathionine beta-lyase (EC 4.4.1.8)
Position: -82 Score: 7.1 Sequence: AGACATCT-(0)-AAACGTCT Locus tag: b0600 Name: mtnE Funciton: Methionine aminotransferase
	b0600	mtnE	Methionine aminotransferase
Position: -318 Score: 5 Sequence: AGATGTCC-(0)-AGATCTTG Locus tag: b3966 Name: btuB Funciton: TonB-dependent outer membrane transporter for vitamin B12
	b3966	btuB	TonB-dependent outer membrane transporter for vitamin B12

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulon of MetJ in Escherichia coli str. K-12 substr. MG1655

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --