Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of MetJ in Photorhabdus luminescens subsp. laumondii TTO1

Properties
Regulator type: Transcription factor
TF locus tag: plu4757
Regulator family: MetJ
Regulation mode: repressor
Biological process: Methionine metabolism; Methionine biosynthesis
Effector: S-adenosylmethionine
Regulog: MetJ - Enterobacteriales
Statistics of regulated genes:
- Genes 14
- Operons 10
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 167 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -214
Score: 6.2
Sequence: AGACATCT-(0)-AAACCTCT
Locus tag: plu4757
Name: metJ
Funciton: S-adenosylmethionine-responsive transcriptional repressor MetJ
metJ
S-adenosylmethionine-responsive transcriptional repressor MetJ

Position: -36
Score: 6.6
Sequence: AAACATCT-(0)-AGACGGCT
Locus tag: plu4420
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

Position: -44
Score: 6.6
Sequence: AGAAGTCT-(0)-AAACGTGT
Locus tag: plu4397
Name: metA
Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
metA
Homoserine O-succinyltransferase (EC 2.3.1.46)

Position: -105
Score: 6.6
Sequence: AGACGTCT-(0)-AGACACCT
Locus tag: plu0697
Name: metN
Funciton: Methionine ABC transporter ATP-binding protein
Locus tag: plu0696
Name: metI
Funciton: Methionine ABC transporter permease protein
Locus tag: plu0695
Name: metQ
Funciton: Methionine ABC transporter substrate-binding protein
metN
Methionine ABC transporter ATP-binding protein
metI
Methionine ABC transporter permease protein
metQ
Methionine ABC transporter substrate-binding protein

Position: -88
Score: 6.7
Sequence: AGCCGTCT-(0)-AGATGTTT
Locus tag: plu4421
Name: metR
Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
metR
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family

Position: -69
Score: 7
Sequence: AGATGTCT-(0)-AGATGTGT
Locus tag: plu4756
Name: metB
Funciton: Cystathionine gamma-synthase (EC 2.5.1.48)
Locus tag: plu4755
Name: metL
Funciton: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
metB
Cystathionine gamma-synthase (EC 2.5.1.48)
metL
Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)

Position: -97
Score: 7
Sequence: GGACGTCT-(0)-AAACGTAT
Locus tag: plu4754
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
metF
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)

Position: -152
Score: 6.4
Sequence: GGAAATCT-(0)-AAACGTCT
Locus tag: plu0524
Name: mccA
Funciton: Cystathionine beta-synthase (EC 4.2.1.22)
Locus tag: plu0523
Name: mccB
Funciton: Cystathionine gamma-lyase (EC 4.4.1.1)
mccA
Cystathionine beta-synthase (EC 4.2.1.22)
mccB
Cystathionine gamma-lyase (EC 4.4.1.1)

Position: -245
Score: 4.7
Sequence: AAACGGCT-(0)-GACTTTCT
Locus tag: plu4735
Name: btuB
Funciton: TonB-dependent outer membrane transporter for vitamin B12
btuB
TonB-dependent outer membrane transporter for vitamin B12

Position: -64
Score: 5.2
Sequence: AGCCATCT-(0)-AGATGTTA
Locus tag: plu3683
Name: metK
Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
metK
S-adenosylmethionine synthetase (EC 2.5.1.6)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD