Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of MetJ in Serratia proteamaculans 568

Properties
Regulator type: Transcription factor
TF locus tag: Spro_4787
Regulator family: MetJ
Regulation mode: repressor
Biological process: Methionine metabolism; Methionine biosynthesis
Effector: S-adenosylmethionine
Regulog: MetJ - Enterobacteriales
Statistics of regulated genes:
- Genes 26
- Operons 18
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 167 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -97
Score: 6.8
Sequence: AGACGTCT-(0)-GGATGTCC
Locus tag: Spro_1044
Name: metE2
Funciton: Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
Spro_1044
metE2
Methionine synthase II, vitamin-B12 independent (EC 2.1.1.14)
Position: -32
Score: 6.7
Sequence: AGCTGTTT-(0)-AGACGTCT
Locus tag: Spro_3470
Name: mmuP
Funciton: S-methylmethionine transporter
Locus tag: Spro_3471
Name: mmuM
Funciton: Homocysteine S-methyltransferase (EC 2.1.1.10)
Spro_3470
mmuP
S-methylmethionine transporter
Spro_3471
mmuM
Homocysteine S-methyltransferase (EC 2.1.1.10)
Position: -80
Score: 5.8
Sequence: GGACGTCT-(0)-ATACATCC
Locus tag: Spro_0945
Name: mtnA
Funciton: Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)
Spro_0945
mtnA
Methylthioribose-1-phosphate isomerase (EC 5.3.1.23)
Position: -88
Score: 6.1
Sequence: AGACGCTT-(0)-AGATGGCT
Locus tag: Spro_0942
Name: mtnB
Funciton: Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)
Locus tag: Spro_0943
Name: mtnC
Funciton: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)
Locus tag: Spro_0944
Name: mtnD
Funciton: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)
Spro_0942
mtnB
Methylthioribulose-1-phosphate dehydratase (EC 4.2.1.109)
Spro_0943
mtnC
2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatase (EC 3.1.3.77)
Spro_0944
mtnD
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (EC 1.13.11.54)
Position: -240
Score: 5.9
Sequence: GGACATCT-(0)-AAACTTCT
Locus tag: Spro_4787
Name: metJ
Funciton: S-adenosylmethionine-responsive transcriptional repressor MetJ
Spro_4787
metJ
S-adenosylmethionine-responsive transcriptional repressor MetJ
Position: -40
Score: 7
Sequence: AGAAGTCT-(0)-AAACGTTT
Locus tag: Spro_4504
Name: metA
Funciton: Homoserine O-succinyltransferase (EC 2.3.1.46)
Spro_4504
metA
Homoserine O-succinyltransferase (EC 2.3.1.46)
Position: -33
Score: 6.2
Sequence: AAACATCT-(0)-GGACGGCT
Locus tag: Spro_0242
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Spro_0242
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
Position: -79
Score: 6.6
Sequence: GGATGTAT-(0)-AGACGTCC
Locus tag: Spro_0946
Name: mtnK
Funciton: 5-methylthioribose kinase (EC 2.7.1.100)
Spro_0946
mtnK
5-methylthioribose kinase (EC 2.7.1.100)
Position: -96
Score: 6.7
Sequence: GGACGTCT-(0)-AGACGCCT
Locus tag: Spro_3753
Name: metN
Funciton: Methionine ABC transporter ATP-binding protein
Locus tag: Spro_3754
Name: metI
Funciton: Methionine ABC transporter permease protein
Locus tag: Spro_3755
Name: metQ
Funciton: Methionine ABC transporter substrate-binding protein
Spro_3753
metN
Methionine ABC transporter ATP-binding protein
Spro_3754
metI
Methionine ABC transporter permease protein
Spro_3755
metQ
Methionine ABC transporter substrate-binding protein
Position: -88
Score: 6.2
Sequence: AGCCGTCC-(0)-AGATGTTT
Locus tag: Spro_0241
Name: metR
Funciton: Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
Spro_0241
metR
Homocysteine-responsive transcriptional regulator of methionine metabolism, LysR family
Position: -85
Score: 6.8
Sequence: AGATGTCC-(0)-AGATGTAT
Locus tag: Spro_4786
Name: metB
Funciton: Cystathionine gamma-synthase (EC 2.5.1.48)
Locus tag: Spro_4785
Name: metL
Funciton: Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
Spro_4786
metB
Cystathionine gamma-synthase (EC 2.5.1.48)
Spro_4785
metL
Aspartokinase (EC 2.7.2.4) / Homoserine dehydrogenase (EC 1.1.1.3)
Position: -68
Score: 7.3
Sequence: AGACGTCT-(0)-AAACGTAT
Locus tag: Spro_4784
Name: metF
Funciton: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Spro_4784
metF
5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)
Position: -89
Score: 6.5
Sequence: AAACGTCT-(0)-GGATGGCT
Locus tag: Spro_4212
Name: metC
Funciton: Cystathionine beta-lyase (EC 4.4.1.8)
Spro_4212
metC
Cystathionine beta-lyase (EC 4.4.1.8)
Position: -28
Score: 6.1
Sequence: AAACACCT-(0)-AAACGTCT
Locus tag: Spro_3218
Name: mtnX
Funciton: Predicted methylthioribose ABC transporter, ATP-binding protein
Locus tag: Spro_3219
Name: mtnY
Funciton: Predicted methylthioribose ABC transporter, permease protein
Spro_3218
mtnX
Predicted methylthioribose ABC transporter, ATP-binding protein
Spro_3219
mtnY
Predicted methylthioribose ABC transporter, permease protein
Position: -170
Score: 5.2
Sequence: AAACGGCT-(0)-GCACATCT
Locus tag: Spro_1627
Name: mccA
Funciton: Cystathionine beta-synthase (EC 4.2.1.22)
Locus tag: Spro_1626
Name: mccB
Funciton: Cystathionine gamma-lyase (EC 4.4.1.1)
Spro_1627
mccA
Cystathionine beta-synthase (EC 4.2.1.22)
Spro_1626
mccB
Cystathionine gamma-lyase (EC 4.4.1.1)
Position: -307
Score: 6.2
Sequence: AGCAGTCT-(0)-AGACATCT
Locus tag: Spro_4770
Name: btuB
Funciton: TonB-dependent outer membrane transporter for vitamin B12
Spro_4770
btuB
TonB-dependent outer membrane transporter for vitamin B12
Position: -177
Score: 5.9
Sequence: AGACGTCC-(0)-AGATGTTA
Locus tag: Spro_3974
Name: metK
Funciton: S-adenosylmethionine synthetase (EC 2.5.1.6)
Spro_3974
metK
S-adenosylmethionine synthetase (EC 2.5.1.6)
Position: -82
Score: 5.6
Sequence: AGCCATCT-(0)-AAGCGTCT
Locus tag: Spro_0941
Name: mtnE
Funciton: Methionine aminotransferase
Spro_0941
mtnE
Methionine aminotransferase
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