Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagated regulons of Klebsiella variicola At-22

Type Regulator Effector Pathway Genes Sites
TF AbgR p-aminobenzoyl-glutamate p-aminobenzoyl-glutamate utilization 2 4
TF AcrR Rhodamine 6G; Ethidium bromide; Proflavin Multidrug resistance 2 2
TF AraC Arabinose Arabinose utilization 4 5
TF ArgR Arginine Arginine biosynthesis; Arginine degradation 15 29
TF AscG Cellobiose-6-phosphate; Beta-glucoside-6-phosphate Beta-glucosides utilization; Cellobiose utilization 4 4
TF BetI Choline Glycine betaine synthesis 2 2
TF BirA Biotin Biotin biosynthesis 2 2
TF Crp Cyclic 3',5'-AMP Carbon catabolism 256 575
TF CueR Copper ion, (Cu+) Copper resistance 3 3
TF DeoR Deoxyribonucleoside utilization 2 3
TF DgoR Galactonate Galactonate utilization 1 1
TF ExuR Galacturonate Galacturonate utilization 8 12
TF FabR Unsaturated acyl-ACP; Unsaturated acyl-CoA Fatty acid biosynthesis 3 3
TF FadR Palmitoyl-CoA; Oleoyl-CoA Fatty acid degradation 9 12
TF Fnr Oxygen Energy metabolism; Anaerobic metabolism 76 151
TF FruR Fructose-1-phosphate; Fructose-1,6-diphosphate Central carbohydrate metabolism 21 23
TF FucR L-fuculose-1-phosphate Fucose utilization 2 2
TF Fur Iron ion, (Fe2+) Iron homeostasis 42 128
TF GalR/GalS Galactose Galactose utilization 7 9
TF GcvA Glycine Glycine metabolism 1 1
TF GlpR Glycerol 3-phosphate Glycerol utilization 5 6
TF GntR Gluconate Gluconate utilization 4 7
TF HexR 2-keto-3-deoxy-6-phosphogluconate Central carbohydrate metabolism 4 4
TF HutC cis-Urocanic acid Histidine utilization 3 3
TF IclR Pyruvate; Glyoxylate Glyoxylate bypass 1 1
TF IlvY 2-Acetolactate Branched-chain amino acid biosynthesis 2 4
TF IscR Iron-sulfur cluster redox state Iron-sulfur cluster biogenesis 2 3
TF KdgR 2-keto-3-deoxygluconate Pectin and polygalacturonate utlization 18 30
TF LeuO Guanosine 3',5'-bis(diphosphate) 2 6
TF LexA DNA damage SOS response 19 23
TF LfaR Sugar utilization 2 3
TF LldR L-lactate Lactate utilization 1 1
TF LsrR 4,5-dihydroxypentan-2,3-dione Quorum sensing; Biofilm formation 2 2
TF LysR LL-2,6-Diaminopimelate Lysine biosynthesis 2 2
TF MalI Maltose utilization 2 2
TF MetR Homocysteine Methionine biosynthesis 7 10
TF MntR Manganese ion, (Mn2+) Manganese homeostasis 3 3
TF ModE Molybdate Molybdopterin biosynthesis; Molybdenum homeostasis 6 6
TF MprA 2,4-Dinitrophenol; Carbonyl cyanide m-chlorophenylhydrazone Multidrug resistance 2 2
TF NadR NAD NAD biosynthesis 3 3
TF NagC N-acetylglucosamine-6-phosphate N-acetylglucosamine utilization 5 8
TF NarP Nitrate; Nitrite Nitrate and nitrite respiration 12 15
TF NhaR Potassium ion Osmotic stress response 1 2
TF NikR Nickel ion, (Ni2+) Nickel homeostasis 1 1
TF NorR Nitric oxide Nitrosative stress response 2 5
TF NrdR Deoxyribonucleotides Ribonucleotide reductases 3 10
TF NsrR Nitric oxide Nitrosative stress response 8 11
TF NtrC Phosphorylated NtrB, signal histidine kinase Nitrogen assimilation 12 25
TF PaaX Phenylacetyl-CoA Phenylacetic acid degradation 2 2
TF PdhR Pyruvate Pyruvate metabolism 3 3
TF PhnF Phosphonate utilization 1 1
TF PurR Hypoxanthine; Guanine Purine metabolism 29 38
TF QorR Energy metabolism 2 2
TF RbsR Ribose Ribose utilization 1 1
TF RcnR Nickel ion, (Ni2+); Cobalt ion, (Co2+) Cobalt resistance; Nickel resistance 2 2
TF RhaR Rhamnose Rhamnose utilization 2 2
TF RhaS Rhamnose Rhamnose utilization 4 4
TF RutR Uracil Pyrimidine utilization 3 3
TF SdaR Glycerate Glucarate utilization; Galactarate utilization 4 4
TF SorC Sorbose Sorbose utilization 1 1
TF SoxR Paraquat Superoxide stress response 3 3
TF TreR Trehalose-6-phosphate Trehalose utilization 1 1
TF TrpR Tryptophan Tryptophan biosynthesis 3 3
TF TyrR Tyrosine; Phenylalanine Aromatic amino acid metabolism 9 16
TF UlaR Ascorbate-6-phosphate Ascorbate utilization 2 3
TF UxuR Glucuronate Glucuronate utilization 3 5
TF ZntR Zinc ion, (Zn2+) Zinc resistance 1 1
TF Zur Zinc ion, (Zn2+) Zinc homeostasis 4 4
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