Propagation of KdgR regulog to Klebsiella variicola At-22

Reference regulog properties
Source regulog:	KdgR - Enterobacteriales
Regulator type:	Transcription factor
Regulator family:	IclR
Regulation mode:	repressor (activator)
Biological process:	Pectin and polygalacturonate utlization
Effector:	2-keto-3-deoxygluconate
Phylum:	Proteobacteria/gamma
Propagated regulon:
Target genome	Klebsiella variicola At-22
Orthologous TF(s)	Kvar_1838
Regulated genes	18

Built upon 159 sites [see more]

Predicted regulatory interactions in *Klebsiella variicola At-22*
	Locus tag	Position	Score	Sequence
Position: -87 Score: 5.3 Sequence: TAATGGAACGATGTTTTAATA Locus tag: Kvar_0225
	Kvar_0225	-87	5.3	TAATGGAACGATGTTTTAATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: kdgK
Ortholog function: 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_03876	-87	5.3	TAATGGAACGATGTTTTAATA

Position: -59 Score: 5.8 Sequence: AAATAAAATAACGTTTCATAA Position: -38 Score: 5.6 Sequence: AAACGAAATGACATTTTATTT Locus tag: Kvar_0803
	Kvar_0803	-59	5.8	AAATAAAATAACGTTTCATAA
		-38	5.6	AAACGAAATGACATTTTATTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: kdgM
Ortholog function: Oligogalacturonate-specific porin protein KdgM
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_03267	-58	5.8	AAATAAAATGATGTTTCATAA
		-37	5.6	AAACGAAATGTCATTTTATTT
Enterobacter sp. 638	Ent638_3298	-54	4.9	AAATAAAATGCAGTTCCATAA
		-33	5.4	AAACGAAATGACATTTTAATT

Position: -300 Score: 5.8 Sequence: ATTTAAAACGATGTTTCATTT Position: -103 Score: 5.6 Sequence: TAATGAAACGATGTTTTGATA Locus tag: Kvar_0804
	Kvar_0804	-300	5.8	ATTTAAAACGATGTTTCATTT
		-103	5.6	TAATGAAACGATGTTTTGATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ogl
Ortholog function: Oligogalacturonate lyase (EC 4.2.2.6)
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_03266	-299	5.8	ATTTAAAACGATGTTTCATTT
		-103	5.6	TAATGAAACAATGTTTTGATA
Enterobacter sp. 638	Ent638_3297	-105	5	CATTGAAACGTCGTTTTGATA

Position: -208 Score: 5.8 Sequence: AAATGAAACATCGTTTTAAAT Locus tag: Kvar_0805
	Kvar_0805	-208	5.8	AAATGAAACATCGTTTTAAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: kduD
Ortholog function: 2-deoxy-D-gluconate 3-dehydrogenase (EC 1.1.1.125)
Escherichia coli str. K-12 substr. MG1655	b2842	-130	6.3	AAATGAAACATTGTTTTATTT
		-63	5.4	AAACGAAACAGTGTTTCACTA
Salmonella typhimurium LT2	STM3017	-123	6.2	AAATGAAACGTTGTTTTATTT
		-58	5.3	AATCAAAACAGTGTTTTGATT
Citrobacter koseri ATCC BAA-895	CKO_04219	-119	6.2	AAATGAAACAACGTTTTATTT
		-51	4.4	AAACGGAACGGTGTTTCGCCT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_03265	-207	5.8	AAATGAAACATCGTTTTAAAT
		-139	5.2	AAACGGAACTCTGTTTTATTT
Enterobacter sp. 638	Ent638_3295	-127	5.4	AACTGAAACAACGTTTTAAAT
		-60	5	AATCGGAACATTGTTTCGTTA

Position: -287 Score: 5 Sequence: TTTTGAAACATCGTTTCGACT Position: -210 Score: 5.6 Sequence: AATTAAAACGGTGTTTTATAA Locus tag: Kvar_0814
	Kvar_0814	-287	5	TTTTGAAACATCGTTTCGACT
		-210	5.6	AATTAAAACGGTGTTTTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: togM
Ortholog function: oligogalacturonide ABC transporter, inner membrane permease
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_03256	-288	5	TTTTGAAACATCGTTTCGACT
		-211	5.6	AATTAAAACGGTGTTTTATAA
Enterobacter sp. 638	Ent638_3289	-226	5.1	AATTAAAACGCCGTTTTACAA
Yersinia pestis KIM	y1884	-152	4.5	AATCAAAACAACGTTCCGACT
		-76	5.2	GATTGAAACGATGTTTCTATT
Erwinia carotovora subsp. atroseptica SCRI1043	ECA2403	-139	4.5	AATCAAAACAACGTTCCGACT
		-61	5.3	AATCAAAACAGTGTTTCTATT

Position: -39 Score: 5.8 Sequence: AAATGAAACAATGTTTCACTT Locus tag: Kvar_0815
	Kvar_0815	-39	5.8	AAATGAAACAATGTTTCACTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: kdgF
Ortholog function: Pectin degradation protein KdgF
Citrobacter koseri ATCC BAA-895	CKO_04218	-38	5.6	AGTTGAAACATTGTTTCAATA
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_03255	-39	5.8	AAATGAAACAATGTTTCACTT
Enterobacter sp. 638	Ent638_3287	-38	5.5	AATTAAAACAATGTTTCACTA
Yersinia pestis KIM	y1888	-155	6	AAATGAAATGATGTTTTATTA
Erwinia carotovora subsp. atroseptica SCRI1043	ECA2399	-174	6.1	AAATGAAATAATGTTTTATTT

Position: -100 Score: 5 Sequence: TTTTGAAACGCCTTTTTAATT Locus tag: Kvar_1462
	Kvar_1462	-100	5	TTTTGAAACGCCTTTTTAATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: setC
Ortholog function: lactose/glucose efflux system
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_02601	-102	5	TTTTGAAACGCCTTTTTAATT
Enterobacter sp. 638	Ent638_2764	-109	4.9	TTTTGAAATGCTATTTTGATT

Position: -7 Score: 5.1 Sequence: ATTTGAAATGTTGTTTCAACA Locus tag: Kvar_1643
	Kvar_1643	-7	5.1	ATTTGAAATGTTGTTTCAACA
Supported by regulated orthologs from reference regulons
Ortholog gene name: yeeO
Ortholog function: predicted multidrug efflux system, MATE family
Escherichia coli str. K-12 substr. MG1655	b1985	-7	4.9	ATTTGAAATGTGGTTTCACTT
Salmonella typhimurium LT2	STM2013	-7	5	TATTGAAATGTGGTTTCAACT
Citrobacter koseri ATCC BAA-895	CKO_00837	-7	4.9	ATTTGAAATGAGGTTTCAACT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_02447	-40	5.1	ATTTGAAATGTTGTTTCAACA
Enterobacter sp. 638	Ent638_2574	-74	5	ATTTGAAATGTAGTTTCAACT
Yersinia pestis KIM	y2593	-158	4.8	TCATGAAACTATGTTCCATTT
Serratia proteamaculans 568	Spro_3106	-39	5.2	ATTTGAAATGTTGTTTCACTT
Erwinia carotovora subsp. atroseptica SCRI1043	ECA2762	-140	5.1	AATAGAAACGTCATTTTAAAA

Position: -46 Score: 5.2 Sequence: TATAAAAACAGTGTTTCAAAA Locus tag: Kvar_1707
	Kvar_1707	-46	5.2	TATAAAAACAGTGTTTCAAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: togT
Ortholog function: Oligogalacturonide transporter
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_02398	-46	5.2	TATAAAAACAGTGTTTCAAAA
Yersinia pestis KIM	y2961	-47	4.5	AAAGAAAACAGTTATTCATTA
		-25	6.1	AAATGAAACATTGTTTTAATT
Erwinia carotovora subsp. atroseptica SCRI1043	ECA0817	-60	4.5	TAAAGAAATGATAGTTCAATC
		-38	5.5	AACTGAAATATTGTTTCATAT

Position: -222 Score: 4.6 Sequence: AAATGAACCTGCCTTTTTATT Position: -200 Score: 5.4 Sequence: AAAAGAAATGCTGTTTTATAA Locus tag: Kvar_1715
	Kvar_1715	-222	4.6	AAATGAACCTGCCTTTTTATT
		-200	5.4	AAAAGAAATGCTGTTTTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: rhiT
Ortholog function: Rhamnogalacturonide transporter
Citrobacter koseri ATCC BAA-895	CKO_01081	-190	5.4	AATAGAAACGCTGTTTTATAA
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_02390	-200	4.9	AAGAGAAATGCTGTTTTATAA
Enterobacter sp. 638	Ent638_2444	-189	5.6	AAAAGAAACGCTGTTTTATAA
Erwinia carotovora subsp. atroseptica SCRI1043	ECA3560	-167	4.7	AGTTAAAATGCCTTTTTATAA

Position: -161 Score: 5 Sequence: AAATGAAACGGTTTTTTGAAT Locus tag: Kvar_1838
	Kvar_1838	-161	5	AAATGAAACGGTTTTTTGAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: kdgR
Ortholog function: 2-keto-3-deoxy-D-gluconate repressor, IclR family
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_02343	-161	5	AAATGAAACGGTTTTTTGAAT

Position: -106 Score: 5.1 Sequence: AACAAAAATAGCGTTTCAATT Locus tag: Kvar_2030
	Kvar_2030	-106	5.1	AACAAAAATAGCGTTTCAATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ppsR
Ortholog function: PEP synthetase regulatory protein
Escherichia coli str. K-12 substr. MG1655	b1703	-131	5.3	AAATGAAATGCTGTTTTCATA
Salmonella typhimurium LT2	STM1348	-131	4.9	AAATGAAACACACTTTTCATT
Citrobacter koseri ATCC BAA-895	CKO_01727	-107	5.5	TATAAAAATAGCGTTTCATTT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_02161	-97	5.1	AACAAAAATAGCGTTTCAATT
Enterobacter sp. 638	Ent638_1744	-107	5.3	ATTAAAAACACCATTTCATTT
Serratia proteamaculans 568	Spro_2173	-134	5.2	ATTTGAAATAGTGTTTTACTT
Erwinia carotovora subsp. atroseptica SCRI1043	ECA1852	-94	5.6	TAATGAAATGGCGTTTTAATA

Position: -254 Score: 5.1 Sequence: AATTGAAACGCTATTTTTGTT Locus tag: Kvar_2031
	Kvar_2031	-254	5.1	AATTGAAACGCTATTTTTGTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ppsA
Ortholog function: Phosphoenolpyruvate synthase (EC 2.7.9.2)
Escherichia coli str. K-12 substr. MG1655	b1702	-222	5.3	TATGAAAACAGCATTTCATTT
Salmonella typhimurium LT2	STM1349	-226	4.9	AATGAAAAGTGTGTTTCATTT
Citrobacter koseri ATCC BAA-895	CKO_01725	-249	5.5	AAATGAAACGCTATTTTTATA
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_02160	-254	5.1	AATTGAAACGCTATTTTTGTT
Enterobacter sp. 638	Ent638_1745	-249	5.3	AAATGAAATGGTGTTTTTAAT
Serratia proteamaculans 568	Spro_2174	-364	5.2	AAgTaAAACAcTaTTTCAaaT
Erwinia carotovora subsp. atroseptica SCRI1043	ECA1853	-227	5.6	TATTAAAACGCCATTTCATTA

Position: -285 Score: 5 Sequence: ATTTGAAACGAGGTTTTTATT Locus tag: Kvar_2142
	Kvar_2142	-285	5	ATTTGAAACGAGGTTTTTATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pykF
Ortholog function: Pyruvate kinase (EC 2.7.1.40)
Escherichia coli str. K-12 substr. MG1655	b1676	-286	5	TTTTGAAACGCTGTTTTTGTT
Salmonella typhimurium LT2	STM1378	-286	4.7	TTTTGAAACAGGGTTTTCATT
Citrobacter koseri ATCC BAA-895	CKO_01709	-286	5	TTTTGAAACGCTGTTTTCATT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_02133	-285	5	ATTTGAAACGAGGTTTTTATT
Enterobacter sp. 638	Ent638_1768	-286	5.1	TTTTGAAACGCCGTTTCCATT
Serratia proteamaculans 568	Spro_2187	-203	4.1	AAtaacAACAcatTTTCATcT
Erwinia carotovora subsp. atroseptica SCRI1043	ECA1867	-259	5.1	ATACGGAACGTCGTTTCAATT

Position: -104 Score: 5.5 Sequence: AACCAAAACACTGTTTCATTT Locus tag: Kvar_3074
	Kvar_3074	-104	5.5	AACCAAAACACTGTTTCATTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: kduD2
Ortholog function: 2-deoxy-D-gluconate 3-dehydrogenase (EC 1.1.1.125)
Citrobacter koseri ATCC BAA-895	CKO_01753	-99	5.9	TTATAAAACACTGTTTCATTT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_01240	-104	5.8	AATCAAAACATTGTTTCATTT
Enterobacter sp. 638	Ent638_1716	-94	5.6	TTTTAAAACATCATTTCATTT

Position: -33 Score: 5.8 Sequence: AAATGAAATGCTGTTTTATAT Locus tag: Kvar_4596
	Kvar_4596	-33	5.8	AAATGAAATGCTGTTTTATAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: yjgK
Ortholog function: cytoplasmic protein involved in polygalacturonate utilization
Escherichia coli str. K-12 substr. MG1655	b4252	-35	6	AAATGAAACGTTGTTTTAATT
Salmonella typhimurium LT2	STM4468	-32	5.7	AAATAAAACGCTGTTTTAACT
Citrobacter koseri ATCC BAA-895	CKO_03553	-33	6.2	AAATGAAACGTTGTTTTATTT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_04658	-33	5.8	AAATGAAATGCTGTTTTATAT
Enterobacter sp. 638	Ent638_0453	-34	6	AAATGAAACATTGTTTTATAT
Yersinia pestis KIM	y0739	-41	5.9	TAATAAAACAGCATTTCATTT
Erwinia carotovora subsp. atroseptica SCRI1043	ECA0383	-41	5.1	TTGTAAAACAGGGTTTCATTT
Edwardsiella tarda EIB202	ETAE_3112	-39	5.6	AAATAAAACGCAGTTTTATAA

Position: -114 Score: 5 Sequence: AACAGAAATGACGTTTCATCA Locus tag: Kvar_4786
	Kvar_4786	-114	5	AACAGAAATGACGTTTCATCA
Supported by regulated orthologs from reference regulons
Ortholog gene name: yjcB
Ortholog function: putative inner membrane protein
Salmonella typhimurium LT2	STM4263	-120	5.4	AATAGAAACAATGTTTCATTC
Citrobacter koseri ATCC BAA-895	CKO_03830	-121	5.1	AACAGAAACGTTGTTTCATTC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	KPN_04460	-113	4.9	AACAGAAATGGCGTTTCATCA

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of KdgR regulog to Klebsiella variicola At-22

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --