Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagation of KdgR regulog to Klebsiella variicola At-22

Reference regulog properties
Source regulog: KdgR - Enterobacteriales
Regulator type: Transcription factor
Regulator family: IclR
Regulation mode: repressor (activator)
Biological process: Pectin and polygalacturonate utlization
Effector: 2-keto-3-deoxygluconate
Phylum: Proteobacteria/gamma
Propagated regulon:
Target genome Klebsiella variicola At-22
Orthologous TF(s) Kvar_1838
Regulated genes 18
Built upon 159 sites [see more]
Predicted regulatory interactions in Klebsiella variicola At-22
Locus tag Position Score Sequence
Position: -87
Score: 5.3
Sequence: TAATGGAACGATGTTTTAATA
Locus tag: Kvar_0225
Kvar_0225 -87 5.3 TAATGGAACGATGTTTTAATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: kdgK
Ortholog function: 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_03876 -87 5.3 TAATGGAACGATGTTTTAATA
Position: -59
Score: 5.8
Sequence: AAATAAAATAACGTTTCATAA
Position: -38
Score: 5.6
Sequence: AAACGAAATGACATTTTATTT
Locus tag: Kvar_0803
Kvar_0803 -59 5.8 AAATAAAATAACGTTTCATAA
-38 5.6 AAACGAAATGACATTTTATTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: kdgM
Ortholog function: Oligogalacturonate-specific porin protein KdgM
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_03267 -58 5.8 AAATAAAATGATGTTTCATAA
-37 5.6 AAACGAAATGTCATTTTATTT
Enterobacter sp. 638 Ent638_3298 -54 4.9 AAATAAAATGCAGTTCCATAA
-33 5.4 AAACGAAATGACATTTTAATT
Position: -300
Score: 5.8
Sequence: ATTTAAAACGATGTTTCATTT
Position: -103
Score: 5.6
Sequence: TAATGAAACGATGTTTTGATA
Locus tag: Kvar_0804
Kvar_0804 -300 5.8 ATTTAAAACGATGTTTCATTT
-103 5.6 TAATGAAACGATGTTTTGATA
Supported by regulated orthologs from reference regulons
Ortholog gene name: ogl
Ortholog function: Oligogalacturonate lyase (EC 4.2.2.6)
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_03266 -299 5.8 ATTTAAAACGATGTTTCATTT
-103 5.6 TAATGAAACAATGTTTTGATA
Enterobacter sp. 638 Ent638_3297 -105 5 CATTGAAACGTCGTTTTGATA
Position: -208
Score: 5.8
Sequence: AAATGAAACATCGTTTTAAAT
Locus tag: Kvar_0805
Kvar_0805 -208 5.8 AAATGAAACATCGTTTTAAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: kduD
Ortholog function: 2-deoxy-D-gluconate 3-dehydrogenase (EC 1.1.1.125)
Escherichia coli str. K-12 substr. MG1655 b2842 -130 6.3 AAATGAAACATTGTTTTATTT
-63 5.4 AAACGAAACAGTGTTTCACTA
Salmonella typhimurium LT2 STM3017 -123 6.2 AAATGAAACGTTGTTTTATTT
-58 5.3 AATCAAAACAGTGTTTTGATT
Citrobacter koseri ATCC BAA-895 CKO_04219 -119 6.2 AAATGAAACAACGTTTTATTT
-51 4.4 AAACGGAACGGTGTTTCGCCT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_03265 -207 5.8 AAATGAAACATCGTTTTAAAT
-139 5.2 AAACGGAACTCTGTTTTATTT
Enterobacter sp. 638 Ent638_3295 -127 5.4 AACTGAAACAACGTTTTAAAT
-60 5 AATCGGAACATTGTTTCGTTA
Position: -287
Score: 5
Sequence: TTTTGAAACATCGTTTCGACT
Position: -210
Score: 5.6
Sequence: AATTAAAACGGTGTTTTATAA
Locus tag: Kvar_0814
Kvar_0814 -287 5 TTTTGAAACATCGTTTCGACT
-210 5.6 AATTAAAACGGTGTTTTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: togM
Ortholog function: oligogalacturonide ABC transporter, inner membrane permease
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_03256 -288 5 TTTTGAAACATCGTTTCGACT
-211 5.6 AATTAAAACGGTGTTTTATAA
Enterobacter sp. 638 Ent638_3289 -226 5.1 AATTAAAACGCCGTTTTACAA
Yersinia pestis KIM y1884 -152 4.5 AATCAAAACAACGTTCCGACT
-76 5.2 GATTGAAACGATGTTTCTATT
Erwinia carotovora subsp. atroseptica SCRI1043 ECA2403 -139 4.5 AATCAAAACAACGTTCCGACT
-61 5.3 AATCAAAACAGTGTTTCTATT
Position: -39
Score: 5.8
Sequence: AAATGAAACAATGTTTCACTT
Locus tag: Kvar_0815
Kvar_0815 -39 5.8 AAATGAAACAATGTTTCACTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: kdgF
Ortholog function: Pectin degradation protein KdgF
Citrobacter koseri ATCC BAA-895 CKO_04218 -38 5.6 AGTTGAAACATTGTTTCAATA
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_03255 -39 5.8 AAATGAAACAATGTTTCACTT
Enterobacter sp. 638 Ent638_3287 -38 5.5 AATTAAAACAATGTTTCACTA
Yersinia pestis KIM y1888 -155 6 AAATGAAATGATGTTTTATTA
Erwinia carotovora subsp. atroseptica SCRI1043 ECA2399 -174 6.1 AAATGAAATAATGTTTTATTT
Position: -100
Score: 5
Sequence: TTTTGAAACGCCTTTTTAATT
Locus tag: Kvar_1462
Kvar_1462 -100 5 TTTTGAAACGCCTTTTTAATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: setC
Ortholog function: lactose/glucose efflux system
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02601 -102 5 TTTTGAAACGCCTTTTTAATT
Enterobacter sp. 638 Ent638_2764 -109 4.9 TTTTGAAATGCTATTTTGATT
Position: -7
Score: 5.1
Sequence: ATTTGAAATGTTGTTTCAACA
Locus tag: Kvar_1643
Kvar_1643 -7 5.1 ATTTGAAATGTTGTTTCAACA
Supported by regulated orthologs from reference regulons
Ortholog gene name: yeeO
Ortholog function: predicted multidrug efflux system, MATE family
Escherichia coli str. K-12 substr. MG1655 b1985 -7 4.9 ATTTGAAATGTGGTTTCACTT
Salmonella typhimurium LT2 STM2013 -7 5 TATTGAAATGTGGTTTCAACT
Citrobacter koseri ATCC BAA-895 CKO_00837 -7 4.9 ATTTGAAATGAGGTTTCAACT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02447 -40 5.1 ATTTGAAATGTTGTTTCAACA
Enterobacter sp. 638 Ent638_2574 -74 5 ATTTGAAATGTAGTTTCAACT
Yersinia pestis KIM y2593 -158 4.8 TCATGAAACTATGTTCCATTT
Serratia proteamaculans 568 Spro_3106 -39 5.2 ATTTGAAATGTTGTTTCACTT
Erwinia carotovora subsp. atroseptica SCRI1043 ECA2762 -140 5.1 AATAGAAACGTCATTTTAAAA
Position: -46
Score: 5.2
Sequence: TATAAAAACAGTGTTTCAAAA
Locus tag: Kvar_1707
Kvar_1707 -46 5.2 TATAAAAACAGTGTTTCAAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: togT
Ortholog function: Oligogalacturonide transporter
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02398 -46 5.2 TATAAAAACAGTGTTTCAAAA
Yersinia pestis KIM y2961 -47 4.5 AAAGAAAACAGTTATTCATTA
-25 6.1 AAATGAAACATTGTTTTAATT
Erwinia carotovora subsp. atroseptica SCRI1043 ECA0817 -60 4.5 TAAAGAAATGATAGTTCAATC
-38 5.5 AACTGAAATATTGTTTCATAT
Position: -222
Score: 4.6
Sequence: AAATGAACCTGCCTTTTTATT
Position: -200
Score: 5.4
Sequence: AAAAGAAATGCTGTTTTATAA
Locus tag: Kvar_1715
Kvar_1715 -222 4.6 AAATGAACCTGCCTTTTTATT
-200 5.4 AAAAGAAATGCTGTTTTATAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: rhiT
Ortholog function: Rhamnogalacturonide transporter
Citrobacter koseri ATCC BAA-895 CKO_01081 -190 5.4 AATAGAAACGCTGTTTTATAA
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02390 -200 4.9 AAGAGAAATGCTGTTTTATAA
Enterobacter sp. 638 Ent638_2444 -189 5.6 AAAAGAAACGCTGTTTTATAA
Erwinia carotovora subsp. atroseptica SCRI1043 ECA3560 -167 4.7 AGTTAAAATGCCTTTTTATAA
Position: -161
Score: 5
Sequence: AAATGAAACGGTTTTTTGAAT
Locus tag: Kvar_1838
Kvar_1838 -161 5 AAATGAAACGGTTTTTTGAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: kdgR
Ortholog function: 2-keto-3-deoxy-D-gluconate repressor, IclR family
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02343 -161 5 AAATGAAACGGTTTTTTGAAT
Position: -106
Score: 5.1
Sequence: AACAAAAATAGCGTTTCAATT
Locus tag: Kvar_2030
Kvar_2030 -106 5.1 AACAAAAATAGCGTTTCAATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ppsR
Ortholog function: PEP synthetase regulatory protein
Escherichia coli str. K-12 substr. MG1655 b1703 -131 5.3 AAATGAAATGCTGTTTTCATA
Salmonella typhimurium LT2 STM1348 -131 4.9 AAATGAAACACACTTTTCATT
Citrobacter koseri ATCC BAA-895 CKO_01727 -107 5.5 TATAAAAATAGCGTTTCATTT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02161 -97 5.1 AACAAAAATAGCGTTTCAATT
Enterobacter sp. 638 Ent638_1744 -107 5.3 ATTAAAAACACCATTTCATTT
Serratia proteamaculans 568 Spro_2173 -134 5.2 ATTTGAAATAGTGTTTTACTT
Erwinia carotovora subsp. atroseptica SCRI1043 ECA1852 -94 5.6 TAATGAAATGGCGTTTTAATA
Position: -254
Score: 5.1
Sequence: AATTGAAACGCTATTTTTGTT
Locus tag: Kvar_2031
Kvar_2031 -254 5.1 AATTGAAACGCTATTTTTGTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: ppsA
Ortholog function: Phosphoenolpyruvate synthase (EC 2.7.9.2)
Escherichia coli str. K-12 substr. MG1655 b1702 -222 5.3 TATGAAAACAGCATTTCATTT
Salmonella typhimurium LT2 STM1349 -226 4.9 AATGAAAAGTGTGTTTCATTT
Citrobacter koseri ATCC BAA-895 CKO_01725 -249 5.5 AAATGAAACGCTATTTTTATA
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02160 -254 5.1 AATTGAAACGCTATTTTTGTT
Enterobacter sp. 638 Ent638_1745 -249 5.3 AAATGAAATGGTGTTTTTAAT
Serratia proteamaculans 568 Spro_2174 -364 5.2 AAgTaAAACAcTaTTTCAaaT
Erwinia carotovora subsp. atroseptica SCRI1043 ECA1853 -227 5.6 TATTAAAACGCCATTTCATTA
Position: -285
Score: 5
Sequence: ATTTGAAACGAGGTTTTTATT
Locus tag: Kvar_2142
Kvar_2142 -285 5 ATTTGAAACGAGGTTTTTATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: pykF
Ortholog function: Pyruvate kinase (EC 2.7.1.40)
Escherichia coli str. K-12 substr. MG1655 b1676 -286 5 TTTTGAAACGCTGTTTTTGTT
Salmonella typhimurium LT2 STM1378 -286 4.7 TTTTGAAACAGGGTTTTCATT
Citrobacter koseri ATCC BAA-895 CKO_01709 -286 5 TTTTGAAACGCTGTTTTCATT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02133 -285 5 ATTTGAAACGAGGTTTTTATT
Enterobacter sp. 638 Ent638_1768 -286 5.1 TTTTGAAACGCCGTTTCCATT
Serratia proteamaculans 568 Spro_2187 -203 4.1 AAtaacAACAcatTTTCATcT
Erwinia carotovora subsp. atroseptica SCRI1043 ECA1867 -259 5.1 ATACGGAACGTCGTTTCAATT
Position: -104
Score: 5.5
Sequence: AACCAAAACACTGTTTCATTT
Locus tag: Kvar_3074
Kvar_3074 -104 5.5 AACCAAAACACTGTTTCATTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: kduD2
Ortholog function: 2-deoxy-D-gluconate 3-dehydrogenase (EC 1.1.1.125)
Citrobacter koseri ATCC BAA-895 CKO_01753 -99 5.9 TTATAAAACACTGTTTCATTT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_01240 -104 5.8 AATCAAAACATTGTTTCATTT
Enterobacter sp. 638 Ent638_1716 -94 5.6 TTTTAAAACATCATTTCATTT
Position: -33
Score: 5.8
Sequence: AAATGAAATGCTGTTTTATAT
Locus tag: Kvar_4596
Kvar_4596 -33 5.8 AAATGAAATGCTGTTTTATAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: yjgK
Ortholog function: cytoplasmic protein involved in polygalacturonate utilization
Escherichia coli str. K-12 substr. MG1655 b4252 -35 6 AAATGAAACGTTGTTTTAATT
Salmonella typhimurium LT2 STM4468 -32 5.7 AAATAAAACGCTGTTTTAACT
Citrobacter koseri ATCC BAA-895 CKO_03553 -33 6.2 AAATGAAACGTTGTTTTATTT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_04658 -33 5.8 AAATGAAATGCTGTTTTATAT
Enterobacter sp. 638 Ent638_0453 -34 6 AAATGAAACATTGTTTTATAT
Yersinia pestis KIM y0739 -41 5.9 TAATAAAACAGCATTTCATTT
Erwinia carotovora subsp. atroseptica SCRI1043 ECA0383 -41 5.1 TTGTAAAACAGGGTTTCATTT
Edwardsiella tarda EIB202 ETAE_3112 -39 5.6 AAATAAAACGCAGTTTTATAA
Position: -114
Score: 5
Sequence: AACAGAAATGACGTTTCATCA
Locus tag: Kvar_4786
Kvar_4786 -114 5 AACAGAAATGACGTTTCATCA
Supported by regulated orthologs from reference regulons
Ortholog gene name: yjcB
Ortholog function: putative inner membrane protein
Salmonella typhimurium LT2 STM4263 -120 5.4 AATAGAAACAATGTTTCATTC
Citrobacter koseri ATCC BAA-895 CKO_03830 -121 5.1 AACAGAAACGTTGTTTCATTC
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_04460 -113 4.9 AACAGAAATGGCGTTTCATCA