Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
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Propagation of NrdR regulog to Klebsiella variicola At-22

Reference regulog properties
Source regulog: NrdR - Enterobacteriales
Regulator type: Transcription factor
Regulator family: NrdR
Regulation mode: repressor
Biological process: Ribonucleotide reductases
Effector: Deoxyribonucleotides
Phylum: Proteobacteria/gamma
Propagated regulon:
Target genome Klebsiella variicola At-22
Orthologous TF(s) Kvar_4016
Regulated genes 3
Built upon 70 sites [see more]
Predicted regulatory interactions in Klebsiella variicola At-22
Locus tag Position Score Sequence
Position: -91
Score: 5.5
Sequence: CAACTACATCTAGTAT
Locus tag: Kvar_1064
Kvar_1064 -91 5.5 CAACTACATCTAGTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: nrdH
Ortholog function: Glutaredoxin-like protein NrdH, required for reduction of Ribonucleotide reductase class Ib
Escherichia coli str. K-12 substr. MG1655 b2673 -120 4.8 TTGCTATATATTGTGT
-89 5.5 CAACTACATCTAGTAT
Salmonella typhimurium LT2 STM2805 -121 4.7 TTCCCATATCTTGTAT
-89 5.5 CAACTACATCTAGTAT
Enterobacter sp. 638 Ent638_3153 -106 4.6 TTCCCATATCTTGTGT
-75 5.5 CAACTACATCTAGTAT
Position: -93
Score: 5.8
Sequence: CCCCTACATATAGTAT
Locus tag: Kvar_1411
Kvar_1411 -93 5.8 CCCCTACATATAGTAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: nrdA
Ortholog function: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_02642 -125 3.7 ACTCACCATATAGCGT
-93 5.8 CCCCTACATATAGTAT
Enterobacter sp. 638 Ent638_2801 -130 3.7 ACTCACCATATAGCGT
-98 5.6 CCCCTATATGTAGTAT
Position: -207
Score: 4.7
Sequence: TCACTACATATAGAAC
Position: -176
Score: 5.1
Sequence: GCCCTACATGTTGTAT
Position: -145
Score: 3.7
Sequence: TCACCATATCTTGTCG
Position: -20
Score: 3.7
Sequence: GTTCTATATATGGAGT
Position: -18
Score: 3.3
Sequence: TCTATATATGGAGTGA
Locus tag: Kvar_4605
Kvar_4605 -207 4.7 TCACTACATATAGAAC
-176 5.1 GCCCTACATGTTGTAT
-145 3.7 TCACCATATCTTGTCG
-20 3.7 GTTCTATATATGGAGT
-18 3.3 TCTATATATGGAGTGA
Supported by regulated orthologs from reference regulons
Ortholog gene name: nrdD
Ortholog function: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
Escherichia coli str. K-12 substr. MG1655 b4238 -208 4.3 GCACTATATATAGACT
-177 5 ACCCAATATGTTGTAT
Salmonella typhimurium LT2 STM4452 -207 4.5 TCACTACATATAGACT
-177 5 ACCCAATATGTTGTAT
Citrobacter koseri ATCC BAA-895 CKO_03580 -225 4.7 TCACTACATATAGAAC
-194 5 ACCCAATATGTTGTAT
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 KPN_04646 -207 4.7 TCACTACATATAGAAC
-176 5 GCCCAACATATTGTAT
Enterobacter sp. 638 Ent638_0437 -203 4.7 TCACTACATATAGAAC
-172 5.1 ACCCAACATCTTGTAT
Erwinia amylovora ATCC 49946 EAM_3059 -67 3 ATACCATATATAGATA
-36 3.4 GGACTATATGTAGTTG
Yersinia pestis KIM y0733 -142 5.1 TACCCATATATAGTGT
-111 4.7 CATCTATATGTAGTAG
Serratia proteamaculans 568 Spro_0525 -189 5 TATCTATATATAGTGC
-158 4.9 CACCTATATGTAGTAG
Erwinia carotovora subsp. atroseptica SCRI1043 ECA0375 -132 4.4 TTTCAATATATAGTGC
-101 5.5 TACCTACATATAGTGT
Edwardsiella tarda EIB202 ETAE_0423 -156 4.8 TTCCCATATATAGTGT
-124 5.1 CACCTATATATAGTAG
Proteus mirabilis HI4320 PMI3451 -143 4.7 TTACTATATATTGTGC
-111 4.2 ATACAACATATAGTAA
Photorhabdus luminescens subsp. laumondii TTO1 plu4499 -119 5.1 TTACTATATATTGTGT
-88 3.8 AGACTATATATAGCAA
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