Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Propagated regulons of Geobacillus sp. Y412MC10

Type Regulator Effector Pathway Genes Sites
TF AdaA DNA alkylation response 1 1
TF AraR Arabinose Arabinose utilization 2 2
TF ArgR Arginine Arginine biosynthesis; Arginine degradation 2 4
TF ArsR Arsenite; Cadmium, ion (Cd2+); Silver ion, (Ag+) Arsenic resistance 1 2
TF AseR Arsenite Arsenic resistance 1 1
TF CcpA HPr, phosphocarrier protein Carbon catabolism 20 24
TF CggR Fructose-1,6-diphosphate Glycolysis 1 1
TF CodY Guanosine triphosphate; Branched-chain amino acids Amino acid metabolism 8 10
TF CtsR Heat shock Heat shock response 1 1
TF CymR O-acetyl-L-serine; CysK, cysteine synthetase Cysteine metabolism 6 6
TF CysL Sulfate; Sulfite; Thiosulfate Sulfite reduction 1 1
TF CzrA Zinc ion, (Zn2+); Silver ion, (Ag+); Nickel ion, (Ni2+); Copper ion, (Cu2+); Cobalt ion, (Co2+); Cadmium, ion (Cd2+) Zinc resistance; Nickel resistance; Copper resistance; Cobalt resistance; Cadmium resistance 2 2
TF FadR Palmitoyl-CoA; Oleoyl-CoA Fatty acid degradation 1 1
TF FapR Malonyl-CoA Fatty acid biosynthesis 2 2
TF Fnr Oxygen Anaerobic metabolism 1 2
TF Fur Iron ion, (Fe2+) Iron homeostasis 11 22
TF GlcR 1 1
TF GlnL GlnK, sensor histidine kinase (glutamine) Aspartate utilization; Glutamine utilization 1 1
TF GlnR Feedback-inhibited GlnA, glutamine synthetase Nitrogen assimilation 2 4
TF HrcA Heat shock Heat shock response 2 2
TF HxlR Formaldehyde Ribulose monophosphate pathway 1 1
TF IolR1 Inositol utilization 1 1
TF LexA DNA damage SOS response 5 10
TF LiaR LiaS, sensor histidine kinase (bacitracin, nisin, ramoplanin, vancomycin) Cell wall-active antibiotics stress response 1 1
TF MhqR 2-Methylhydroquinone and catechol resistance 4 5
TF MntR Manganese ion, (Mn2+) Manganese homeostasis 1 1
TF MtlR MtlA, mannitol-specific enzyme IICB PTS component; HPr, phosphocarrier protein Mannitol utilization 1 1
TF NrdR Deoxyribonucleotides Deoxyribonucleotide biosynthesis 1 2
TF PerR Hydrogen peroxide; Manganese ion, (Mn2+); Iron ion, (Fe2+) Oxidative stress response; Peroxide stress response 3 3
TF PurR 5-phosphoribosyl 1-pyrophosphate Purine metabolism 3 3
TF RbsR Ribose Ribose utilization 1 1
TF Rex NADH Energy metabolism 1 3
TF RhgR Rhamnogalacturonides utilization 1 1
TF TnrA NrgB, ammonium uptake protein; NrgA, ammonium uptake protein; Feedback-inhibited GlnA, glutamine synthetase Nitrogen assimilation 13 29
TF TreR Trehalose-6-phosphate Trehalose utilization 1 2
TF UxuR Aldotetraouronic acid Glucuronate utilization 1 1
TF XylR Xylose Xylose utilization 2 2
TF YbzH Metabolite transport 1 1
TF YdfD/YisV Metabolite transport 1 1
TF YdfF 2 2
TF YhcF Multidrug resistance; Multidrug efflux 1 1
TF YodB/CatR Diamide; Quinone Oxidative stress response 1 1
TF YrkD Multidrug resistance 3 3
TF YtcD 1 1
TF YwbI Cell wall metabolism 1 1
TF YybA Polyamine homeostasis 1 1
TF Zur Zinc ion, (Zn2+) Zinc homeostasis 3 3