Regulog CblR - Thermococcales
| Regulator type: | Transcription factor |
| Regulator family: | |
| Regulation mode: | |
| Biological process: | Cobalamin biosynthesis |
| Effector: | |
| Phylum: | Euryarchaeota |
| Visualization: | |
|
Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Thermococcales
- By trascription factor - CblR
- By pathway - Cobalamin biosynthesis
| Genome | Genes | Operons |
|---|---|---|
| Pyrococcus abyssi GE5 | 16 | 10 |
| Pyrococcus furiosus DSM 3638 | 22 | 10 |
| Pyrococcus horikoshii OT3 | 18 | 10 |
| Thermococcus gammatolerans EJ3 | 26 | 14 |
| Thermococcus kodakaraensis KOD1 | 20 | 11 |
| Thermococcus onnurineus NA1 | 22 | 13 |
| Thermococcus sibiricus MM 739 | 8 | 6 |
| Genes | Function | |||||||
|---|---|---|---|---|---|---|---|---|
| CRON 1. | ||||||||
| meaB |
*
Pyrococcus abyssi GE5 Site: position = -26 score = 5.54965 sequence = TTGGATAAATTCTCCAG Gene: PAB2398: GTP-dependent assembly of methylmalonyl-CoA mutase |
*
Pyrococcus furiosus DSM 3638 Site: position = -26 score = 5.54965 sequence = TTGGATAATTTCTCCAG Gene: PF1947: GTP-dependent assembly of methylmalonyl-CoA mutase |
*
Pyrococcus horikoshii OT3 Site: position = -26 score = 5.54965 sequence = TTGGATAATTTCTCCAG Gene: PH0274: GTP-dependent assembly of methylmalonyl-CoA mutase |
*
Thermococcus gammatolerans EJ3 Site: position = -25 score = 5.54965 sequence = TTGGATAATTTCTCCAG Gene: TGAM_1930: GTP-dependent assembly of methylmalonyl-CoA mutase |
*
Thermococcus kodakaraensis KOD1 Site: position = -27 score = 4.98773 sequence = CTGGATGATTAATCCAG Gene: TK0329: GTP-dependent assembly of methylmalonyl-CoA mutase |
*
Thermococcus onnurineus NA1 Site: position = -26 score = 5.41445 sequence = TTGGATAATTTGTCCGA Gene: TON_1075: GTP-dependent assembly of methylmalonyl-CoA mutase |
*
Thermococcus sibiricus MM 739 Site: position = -17 score = 5.75444 sequence = TTGGATAATTAATCCAA Gene: TSIB_1401: GTP-dependent assembly of methylmalonyl-CoA mutase |
GTP-dependent assembly of methylmalonyl-CoA mutase |
| mceE |
Gene: PAB2438: Methylmalonyl-CoA epimerase (EC 5.1.99.1) |
Gene: PF1948: Methylmalonyl-CoA epimerase (EC 5.1.99.1) |
Gene: PH0272: Methylmalonyl-CoA epimerase (EC 5.1.99.1) |
Gene: TGAM_1929: Methylmalonyl-CoA epimerase (EC 5.1.99.1) |
Gene: TK0330: Methylmalonyl-CoA epimerase (EC 5.1.99.1) |
Gene: TON_1074: Methylmalonyl-CoA epimerase (EC 5.1.99.1) |
Gene: TSIB_1400: Methylmalonyl-CoA epimerase (EC 5.1.99.1) |
Methylmalonyl-CoA epimerase (EC 5.1.99.1) |
| CRON 2. | ||||||||
| mutB_C |
*
Pyrococcus abyssi GE5 Site: position = -72 score = 5.05534 sequence = TGGGATAATATATCCAT Gene: PAB2187: B12 binding domain of Methylmalonyl-CoA mutase (EC 5.4.99.2) |
*
Pyrococcus furiosus DSM 3638 Site: position = -78 score = 5.14126 sequence = TAGGATAAAATGTCCAA Gene: PF1946: B12 binding domain of Methylmalonyl-CoA mutase (EC 5.4.99.2) |
*
Pyrococcus horikoshii OT3 Site: position = -61 score = 4.94022 sequence = CGGGATAAAATATCCAT Gene: PH0275: B12 binding domain of Methylmalonyl-CoA mutase (EC 5.4.99.2) |
*
Thermococcus gammatolerans EJ3 Site: position = -77 score = 5.09035 sequence = GTGGACAAAAAATCCAA Gene: TGAM_1931: B12 binding domain of Methylmalonyl-CoA mutase (EC 5.4.99.2) |
*
Thermococcus kodakaraensis KOD1 Site: position = -87 score = 5.52924 sequence = CTGGACAAAATATCCAA Gene: TK0328: B12 binding domain of Methylmalonyl-CoA mutase (EC 5.4.99.2) |
*
Thermococcus onnurineus NA1 Site: position = -87 score = 5.52924 sequence = CTGGACAAAATATCCAA Gene: TON_1076: B12 binding domain of Methylmalonyl-CoA mutase (EC 5.4.99.2) |
*
Thermococcus sibiricus MM 739 Site: position = -87 score = 5.65647 sequence = ATGGATAAAATATCCAA Gene: TSIB_1402: B12 binding domain of Methylmalonyl-CoA mutase (EC 5.4.99.2) |
B12 binding domain of Methylmalonyl-CoA mutase (EC 5.4.99.2) |
| CRON 3. | ||||||||
| mutB_N |
*
Pyrococcus abyssi GE5 Site: position = -81 score = 5.32731 sequence = TTAGATAATTTATCCAA Gene: PAB1800: Methylmalonyl-CoA mutase (EC 5.4.99.2), alpha subunit, N-terminal |
*
Pyrococcus furiosus DSM 3638 Site: position = -83 score = 4.64086 sequence = GTGGATAAAAAAGCCAG Gene: PF1477: Methylmalonyl-CoA mutase (EC 5.4.99.2), alpha subunit, N-terminal |
*
Pyrococcus horikoshii OT3 Site: position = -77 score = 4.87505 sequence = TTGAACAAAATGTCCAA Gene: PH1306: Methylmalonyl-CoA mutase (EC 5.4.99.2), alpha subunit, N-terminal |
*
Thermococcus gammatolerans EJ3 Site: position = -87 score = 5.34267 sequence = CTGGACTTTTTATCCAA Gene: TGAM_1685: Methylmalonyl-CoA mutase (EC 5.4.99.2), alpha subunit, N-terminal |
*
Thermococcus kodakaraensis KOD1 Site: position = -89 score = 5.6419 sequence = ATGGACAATTTATCCAA Gene: TK1149: Methylmalonyl-CoA mutase (EC 5.4.99.2), alpha subunit, N-terminal |
*
Thermococcus onnurineus NA1 Site: position = -88 score = 5.52924 sequence = CTGGACAATATATCCAA Gene: TON_1110: Methylmalonyl-CoA mutase (EC 5.4.99.2), alpha subunit, N-terminal |
*
Thermococcus sibiricus MM 739 Site: position = -88 score = 5.52924 sequence = CTGGATAAAATGTCCAA Gene: TSIB_0812: Methylmalonyl-CoA mutase (EC 5.4.99.2), alpha subunit, N-terminal |
Methylmalonyl-CoA mutase (EC 5.4.99.2), alpha subunit, N-terminal |
| CRON 4. | ||||||||
| TON_1664 |
|
|
|
|
|
*
Thermococcus onnurineus NA1 Site: position = -29 score = 5.06159 sequence = GCGGATAAAATATCCAA Gene: TON_1664: anion transporter |
|
anion transporter |
| sucD |
*
Pyrococcus abyssi GE5 Site: position = -62 score = 5.6134 sequence = TTGGATATTTAATCCAA Gene: PAB1230: Archaeal succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) |
*
Pyrococcus furiosus DSM 3638 Site: position = -71 score = 5.6134 sequence = TTGGATATTTAATCCAA Gene: PF0233: Archaeal succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) |
*
Pyrococcus horikoshii OT3 Site: position = -63 score = 5.45779 sequence = TTGGATATTTAGTCCAA Gene: PH1928: Archaeal succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) |
*
Thermococcus gammatolerans EJ3 Site: position = -67 score = 5.51298 sequence = ATGGATAAAATATCCAT Gene: TGAM_0218: Archaeal succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) |
*
Thermococcus kodakaraensis KOD1 Site: position = -69 score = 5.18538 sequence = ATGGATATAAAATCCAT Gene: TK1880: Archaeal succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) |
Gene: TON_1665: Archaeal succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) |
Gene: TSIB_1965: Archaeal succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) |
Archaeal succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) |
| CRON 5. | ||||||||
| cobS |
Gene: PAB2320: Cobalamin-5-phosphate synthase |
*2
Pyrococcus furiosus DSM 3638 Gene: PF0837: Cobalamin-5-phosphate synthase Site: position = -25 score = 5.14933 sequence = TTGGATTAATTAGCCAG Gene: PF0836: Cobalamin-5-phosphate synthase |
Gene: PH0373: Cobalamin-5-phosphate synthase |
Gene: TGAM_0538: Cobalamin-5-phosphate synthase |
Gene: TK0857: Cobalamin-5-phosphate synthase |
Gene: TON_0684: Cobalamin-5-phosphate synthase |
|
Cobalamin-5-phosphate synthase |
| PAB7298 |
|
Gene: PF0838: Function Code: 16.1 Conserved Hypothetical |
|
|
|
|
|
hypothetical protein |
| PF0839 |
|
Gene: PF0839: Function Code: 16.1 Conserved Hypothetical |
|
|
|
|
|
Function Code: 16.1 Conserved Hypothetical |
| cobY |
Gene: PAB2323: Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62) |
2
Pyrococcus furiosus DSM 3638 Gene: PF0841: Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62) Gene: PF0840: Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62) |
Gene: PH0372: Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62) |
|
Gene: TK0856: Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62) |
Gene: TON_0686: Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62) |
Gene: TSIB_2027: Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62) |
Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62) |
| PF0841.1n |
|
Gene: PF0841.1n: hypothetical protein |
|
|
|
|
|
hypothetical protein |
| PAB3017 |
Gene: PAB3017: hypothetical protein |
|
Gene: PH0373.1n: hypothetical protein |
|
*
Thermococcus kodakaraensis KOD1 Site: position = -42 score = 5.05018 sequence = ATGGATAAAAACTCCAT Gene: TK0862: hypothetical protein |
*
Thermococcus onnurineus NA1 Site: position = -41 score = 4.6169 sequence = AAGGATAAAACATCCAA Gene: TON_0681: hypothetical protein |
|
hypothetical protein |
| PH0375 |
|
|
*
Pyrococcus horikoshii OT3 Site: position = -41 score = 5.05018 sequence = ATGGATAAAAACTCCAT Gene: PH0375: conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71 |
|
Gene: TK0861: conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71 |
Gene: TON_0682: conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71 |
|
conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71 |
| TGAM_0541 |
|
|
|
Gene: TGAM_0541: hypothetical protein |
Gene: TK0860: hypothetical protein |
|
|
hypothetical protein |
| TGAM_0540 |
|
|
|
Gene: TGAM_0540: hypothetical protein |
Gene: TK0859: hypothetical protein |
|
|
hypothetical protein |
| cobZ |
*
Pyrococcus abyssi GE5 Site: position = -48 score = 4.98725 sequence = TTGGATAAAAGCTCCAA Gene: PAB2319: Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73) |
Gene: PF0294: Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73) |
Gene: PH0374: Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73) |
Gene: TGAM_0539: Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73) |
Gene: TK0858: Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73) |
Gene: TON_0683: Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73) |
|
Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73) |
| PAB0415 |
|
Gene: PF0295: conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71 |
|
*
Thermococcus gammatolerans EJ3 Site: position = -41 score = 4.84376 sequence = ATGGATAAAAGCTCCAA Gene: TGAM_0542: N-type ATP pyrophosphatase, putative |
|
|
|
conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71 |
| cbiB |
*
Pyrococcus abyssi GE5 Site: position = -31 score = 4.98725 sequence = TTGGAGCTTTTATCCAA Gene: PAB0025: Adenosylcobinamide-phosphate synthase |
*
Pyrococcus furiosus DSM 3638 Site: position = -19 score = 5.06159 sequence = GCGGATAAAATATCCAA Gene: PF0296: Adenosylcobinamide-phosphate synthase |
*
Pyrococcus horikoshii OT3 Site: position = -23 score = 5.05018 sequence = ATGGAGTTTTTATCCAT Gene: PH0376: Adenosylcobinamide-phosphate synthase |
Gene: TGAM_0544: Adenosylcobinamide-phosphate synthase |
|
Gene: TON_0679: Adenosylcobinamide-phosphate synthase |
|
Adenosylcobinamide-phosphate synthase |
| cobD |
Gene: PAB0026: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) |
Gene: PF0293: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) |
Gene: PH0377: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) |
Gene: TGAM_0545: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) |
|
Gene: TON_0678: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) |
|
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) |
| TGAM_0543 |
|
|
|
*
Thermococcus gammatolerans EJ3 Site: position = 0 score = 4.84376 sequence = TTGGAGCTTTTATCCAT Gene: TGAM_0543: Uracil-DNA glycosylase superfamily protein |
|
*
Thermococcus onnurineus NA1 Site: position = -18 score = 4.6169 sequence = TTGGATGTTTTATCCTT Gene: TON_0680: Uracil-DNA glycosylase superfamily protein |
|
Uracil-DNA glycosylase superfamily protein |
| btuF |
*
Pyrococcus abyssi GE5 Site: position = -30 score = 4.83212 sequence = CTGGACGAATAATCCAG Gene: PAB0349: Vitamin B12 ABC transporter, B12-binding component BtuF |
*
Pyrococcus furiosus DSM 3638 Site: position = -29 score = 5.21796 sequence = TTGGATGATTAATCCAA Site: position = -72 score = 5.6134 sequence = TTGGATTTTTTATCCAA Gene: PF1774: Vitamin B12 ABC transporter, B12-binding component BtuF |
*
Pyrococcus horikoshii OT3 Site: position = -74 score = 5.3143 sequence = TTGGACTTTTTATCCAT Site: position = -29 score = 5.06235 sequence = TTGGACGAATAATCCAA Gene: PH1659: Vitamin B12 ABC transporter, B12-binding component BtuF |
*
Thermococcus gammatolerans EJ3 Site: position = -17 score = 5.36859 sequence = CTGGACAATTAATCCAG Site: position = -65 score = 4.96684 sequence = TTGGACGTTATATCCAA Gene: TGAM_0480: Vitamin B12 ABC transporter, B12-binding component BtuF |
*
Thermococcus kodakaraensis KOD1 Site: position = -26 score = 4.99766 sequence = CCGGACAAATAATCCAG Site: position = -73 score = 4.61789 sequence = TTGGCCGTTTTATCCAA Gene: TK0865: Vitamin B12 ABC transporter, B12-binding component BtuF |
*
Thermococcus onnurineus NA1 Site: position = -73 score = 5.01088 sequence = ATGGCCAAAATATCCAA Site: position = -26 score = 5.34022 sequence = ATGGACAAATAATCCAG Gene: TON_0546: Vitamin B12 ABC transporter, B12-binding component BtuF |
*
Thermococcus sibiricus MM 739 Site: position = 56 score = 5.64436 sequence = TTGGACAAAATATCCAA Gene: TSIB_1577: Vitamin B12 ABC transporter, B12-binding component BtuF |
Vitamin B12 ABC transporter, B12-binding component BtuF |
| CRON 6. | ||||||||
| nrdD |
*
Pyrococcus abyssi GE5 Site: position = 58 score = 5.47236 sequence = TTGGATTTAATATCCAA Gene: PAB2337: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2) |
*
Pyrococcus furiosus DSM 3638 Site: position = -99 score = 5.16649 sequence = ATGGATATTTTAGCCAA Site: position = -29 score = 5.64436 sequence = TTGGACAAAATATCCAA Gene: PF1971: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2) |
*
Pyrococcus horikoshii OT3 Site: position = -28 score = 5.64436 sequence = TTGGACAAAATATCCAA Site: position = -99 score = 5.79996 sequence = TTGGATATTTTATCCAA Gene: PH0021: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2) |
*
Thermococcus gammatolerans EJ3 Site: position = -17 score = 5.82589 sequence = TTGGATAATTTATCCAG Gene: TGAM_0161: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2) |
*
Thermococcus kodakaraensis KOD1 Site: position = -35 score = 5.82589 sequence = TTGGATAAATTATCCAG Site: position = -127 score = 5.941 sequence = TTGGATAATTTATCCAA Gene: TK2298: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2) |
*
Thermococcus onnurineus NA1 Site: position = -27 score = 5.82589 sequence = TTGGATAAATTATCCAG Gene: TON_1870: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2) |
|
Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2) |
| nrdG |
Gene: PAB2338: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) |
Gene: PF1972: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) |
Gene: PH0020: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) |
Gene: TGAM_0160: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) |
Gene: TK2299: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) |
Gene: TON_1871: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) |
|
Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) |
| CRON 7. | ||||||||
| cobT |
*
Pyrococcus abyssi GE5 Site: position = -27 score = 4.98725 sequence = TTGGATAAAACCTCCAA Gene: PAB2326: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
*
Pyrococcus furiosus DSM 3638 Site: position = -27 score = 5.32641 sequence = ATGGATAAAAAATCCAT Gene: PF0303: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
*
Pyrococcus horikoshii OT3 Site: position = -19 score = 5.04355 sequence = TTGGACAAAATTTCCAT Gene: PH0034: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
*
Thermococcus gammatolerans EJ3 Site: position = -27 score = 4.85461 sequence = CTGGATAAAAACTCCAC Gene: TGAM_0534: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
*
Thermococcus kodakaraensis KOD1 Site: position = -27 score = 4.97523 sequence = CTGGATAAAAAGTCCAC Gene: TK0853: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
*
Thermococcus onnurineus NA1 Site: position = -27 score = 4.84376 sequence = TTGGATAAAACCTCCAT Gene: TON_0688: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
|
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
| CRON 8. | ||||||||
| btuC |
*
Pyrococcus abyssi GE5 Site: position = -19 score = 4.99803 sequence = ATGGAATATTTGTCCAA Gene: PAB1535: Vitamin B12 ABC transporter, permease component BtuC |
*
Pyrococcus furiosus DSM 3638 Site: position = -19 score = 4.65153 sequence = TTGGCATATTTGTCCAA Gene: PF0503: Vitamin B12 ABC transporter, permease component BtuC |
*
Pyrococcus horikoshii OT3 Site: position = -20 score = 4.4397 sequence = GTGGCATATTTATCCAA Gene: PH0790: Vitamin B12 ABC transporter, permease component BtuC |
*
Thermococcus gammatolerans EJ3 Site: position = -20 score = 4.95132 sequence = CTGGACAAAAACTCCAG Gene: TGAM_2054: Vitamin B12 ABC transporter, permease component BtuC |
*
Thermococcus kodakaraensis KOD1 Site: position = -20 score = 5.07195 sequence = CTGGACAAAAAGTCCAG Gene: TK2209: Vitamin B12 ABC transporter, permease component BtuC |
*
Thermococcus onnurineus NA1 Site: position = -21 score = 4.86394 sequence = GTGGACAAATAATCCAC Gene: TON_1424: Vitamin B12 ABC transporter, permease component BtuC |
*
Thermococcus sibiricus MM 739 Site: position = -24 score = 5.63932 sequence = TTGGATAAATAATCCAG Gene: TSIB_1460: Vitamin B12 ABC transporter, permease component BtuC |
Vitamin B12 ABC transporter, permease component BtuC |
| btuD |
Gene: PAB1536: Vitamin B12 ABC transporter, ATPase component BtuD |
Gene: PF0502: Vitamin B12 ABC transporter, ATPase component BtuD |
Gene: PH0791: Vitamin B12 ABC transporter, ATPase component BtuD |
Gene: TGAM_2053: Vitamin B12 ABC transporter, ATPase component BtuD |
Gene: TK2208: Vitamin B12 ABC transporter, ATPase component BtuD |
Gene: TON_1425: Vitamin B12 ABC transporter, ATPase component BtuD |
Gene: TSIB_1459: Vitamin B12 ABC transporter, ATPase component BtuD |
Vitamin B12 ABC transporter, ATPase component BtuD |
| CRON 9. | ||||||||
| nrdJ |
Gene: PAB1057: Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1) @ intein-containing |
Gene: PF0440: Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1) @ intein-containing |
Gene: PH0363: Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1) @ intein-containing |
*
Thermococcus gammatolerans EJ3 Site: position = -187 score = 5.27096 sequence = ATGGACAAATTATCCGA Gene: TGAM_0422: Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1) @ intein-containing |
*
Thermococcus kodakaraensis KOD1 Site: position = -198 score = 4.99031 sequence = ATGGATAATTCGTCCAG Gene: TK1736: Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1) @ intein-containing |
*
Thermococcus onnurineus NA1 Site: position = -186 score = 5.41445 sequence = TTGGATAATTTGTCCGA Gene: TON_1816: Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1) @ intein-containing |
*
Thermococcus sibiricus MM 739 Site: position = -185 score = 5.42903 sequence = TTGGATAAAATATCCGA Gene: TSIB_1142: Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1) @ intein-containing |
Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1) @ intein-containing |
| CRON 10. | ||||||||
| btuR |
Gene: PAB2289: Cob(I)alamin adenosyltransferase (EC 2.5.1.17) |
Gene: PF2038: Cob(I)alamin adenosyltransferase (EC 2.5.1.17) |
Gene: PH0075: Cob(I)alamin adenosyltransferase (EC 2.5.1.17) |
*
Thermococcus gammatolerans EJ3 Site: position = -27 score = 4.9848 sequence = TTGGAGGATTTATCCAT Gene: TGAM_0096: Cob(I)alamin adenosyltransferase (EC 2.5.1.17) |
*
Thermococcus kodakaraensis KOD1 Site: position = -28 score = 5.11197 sequence = CTGGAGATTATGTCCAA Gene: TK2130: Cob(I)alamin adenosyltransferase (EC 2.5.1.17) |
*
Thermococcus onnurineus NA1 Site: position = -31 score = 4.41015 sequence = CTGGCGATTATATCCAC Gene: TON_1529: Cob(I)alamin adenosyltransferase (EC 2.5.1.17) |
Gene: TSIB_0909: Cob(I)alamin adenosyltransferase (EC 2.5.1.17) |
Cob(I)alamin adenosyltransferase (EC 2.5.1.17) |
| CRON 11. | ||||||||
| cbiP |
|
Gene: PF0301: Cobyrinic acid ac-diamide synthase |
|
*
Thermococcus gammatolerans EJ3 Site: position = -44 score = 4.85461 sequence = GTGGAGTTTTTATCCAG Gene: TGAM_0535: Cobyrinic acid ac-diamide synthase |
Gene: TK0854: Cobyrinic acid ac-diamide synthase |
*
Thermococcus onnurineus NA1 Site: position = -58 score = 4.84376 sequence = ATGGAGGTTTTATCCAA Gene: TON_0687: Cobyrinic acid ac-diamide synthase |
|
Cobyrinic acid ac-diamide synthase |
| CRON 12. | ||||||||
| mmdA |
Gene: PAB1769: Methylmalonyl-CoA decarboxylase, alpha chain (EC 4.1.1.41) |
Gene: PF0671: Methylmalonyl-CoA decarboxylase, alpha chain (EC 4.1.1.41) |
Gene: PH1287: Methylmalonyl-CoA decarboxylase, alpha chain (EC 4.1.1.41) |
*
Thermococcus gammatolerans EJ3 Site: position = -98 score = 5.05051 sequence = GTGGACAAATTATCCAC Gene: TGAM_2026: Methylmalonyl-CoA decarboxylase, alpha chain (EC 4.1.1.41) |
Gene: TK1622: Methylmalonyl-CoA decarboxylase, alpha chain (EC 4.1.1.41) |
Gene: TON_0041: Methylmalonyl-CoA decarboxylase, alpha chain (EC 4.1.1.41) |
Gene: TSIB_1534: Methylmalonyl-CoA decarboxylase, alpha chain (EC 4.1.1.41) |
Methylmalonyl-CoA decarboxylase, alpha chain (EC 4.1.1.41) |
| mmdD |
Gene: PAB1770: Methylmalonyl-CoA decarboxylase, gamma chain (EC 4.1.1.41) |
Gene: PF0672: Methylmalonyl-CoA decarboxylase, gamma chain (EC 4.1.1.41) |
Gene: PH1285: Methylmalonyl-CoA decarboxylase, gamma chain (EC 4.1.1.41) |
Gene: TGAM_2027: Methylmalonyl-CoA decarboxylase, gamma chain (EC 4.1.1.41) |
Gene: TK1623: Methylmalonyl-CoA decarboxylase, gamma chain (EC 4.1.1.41) |
Gene: TON_0040: Methylmalonyl-CoA decarboxylase, gamma chain (EC 4.1.1.41) |
Gene: TSIB_1535: Methylmalonyl-CoA decarboxylase, gamma chain (EC 4.1.1.41) |
Methylmalonyl-CoA decarboxylase, gamma chain (EC 4.1.1.41) |
| mmdC |
Gene: PAB1771: Biotin carboxyl carrier protein of methylmalonyl-CoA decarboxylase |
Gene: PF0673: Biotin carboxyl carrier protein of methylmalonyl-CoA decarboxylase |
Gene: PH1284: Biotin carboxyl carrier protein of methylmalonyl-CoA decarboxylase |
Gene: TGAM_2028: Biotin carboxyl carrier protein of methylmalonyl-CoA decarboxylase |
Gene: TK1624: Biotin carboxyl carrier protein of methylmalonyl-CoA decarboxylase |
Gene: TON_0039: Biotin carboxyl carrier protein of methylmalonyl-CoA decarboxylase |
Gene: TSIB_1536: Biotin carboxyl carrier protein of methylmalonyl-CoA decarboxylase |
Biotin carboxyl carrier protein of methylmalonyl-CoA decarboxylase |
| mmdB |
Gene: PAB1772: Methylmalonyl-CoA decarboxylase, beta chain (EC 4.1.1.41) |
Gene: PF0674: Methylmalonyl-CoA decarboxylase, beta chain (EC 4.1.1.41) |
Gene: PH1283: Methylmalonyl-CoA decarboxylase, beta chain (EC 4.1.1.41) |
Gene: TGAM_2029: Methylmalonyl-CoA decarboxylase, beta chain (EC 4.1.1.41) |
Gene: TK1625: Methylmalonyl-CoA decarboxylase, beta chain (EC 4.1.1.41) |
Gene: TON_0038: Methylmalonyl-CoA decarboxylase, beta chain (EC 4.1.1.41) |
Gene: TSIB_1537: Methylmalonyl-CoA decarboxylase, beta chain (EC 4.1.1.41) |
Methylmalonyl-CoA decarboxylase, beta chain (EC 4.1.1.41) |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |