Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing cobS gene

Properties
Regulog: CblR - Thermococcales
Regulator type: Transcription factor
Regulator family:
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector:
Phylum: Euryarchaeota
Built upon 82 sites [see more]
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Pyrococcus abyssi GE5
Position: -48
Score: 4.98725
Sequence: TTGGATAAAAGCTCCAA
Locus tag: PAB2319
Name: cobZ
Funciton: Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73)
Locus tag: PAB3017
Name: null
Funciton: hypothetical protein
Locus tag: PAB2320
Name: cobS
Funciton: Cobalamin-5-phosphate synthase
cobZ-PAB3017-cobS -48 5 TTGGATAAAAGCTCCAA PAB2319
Pyrococcus furiosus DSM 3638
Position: -25
Score: 5.14933
Sequence: TTGGATTAATTAGCCAG
Locus tag: PF0836
Name: cobS
Funciton: Cobalamin-5-phosphate synthase
Locus tag: PF0837
Name: cobS
Funciton: Cobalamin-5-phosphate synthase
Locus tag: PF0838
Name: null
Funciton: Function Code: 16.1 Conserved Hypothetical
Locus tag: PF0839
Name: null
Funciton: Function Code: 16.1 Conserved Hypothetical
Locus tag: PF0840
Name: cobY
Funciton: Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62)
Locus tag: PF0841
Name: cobY
Funciton: Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62)
Locus tag: PF0841.1n
Name: null
Funciton: hypothetical protein
cobS-cobS-PF0838-PF0839-cobY-cobY-PF0841.1n -25 5.1 TTGGATTAATTAGCCAG PF0836
Pyrococcus horikoshii OT3
Position: -41
Score: 5.05018
Sequence: ATGGATAAAAACTCCAT
Locus tag: PH0375
Name: null
Funciton: conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71
Locus tag: PH0374
Name: cobZ
Funciton: Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73)
Locus tag: PH0373.1n
Name: null
Funciton: hypothetical protein
Locus tag: PH0373
Name: cobS
Funciton: Cobalamin-5-phosphate synthase
Locus tag: PH0372
Name: cobY
Funciton: Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62)
PH0375-cobZ-PH0373.1n-cobS-cobY -41 5.1 ATGGATAAAAACTCCAT PH0375
Thermococcus gammatolerans EJ3
Position: -41
Score: 4.84376
Sequence: ATGGATAAAAGCTCCAA
Locus tag: TGAM_0542
Name: null
Funciton: N-type ATP pyrophosphatase, putative
Locus tag: TGAM_0541
Name: null
Funciton: hypothetical protein
Locus tag: TGAM_0540
Name: null
Funciton: hypothetical protein
Locus tag: TGAM_0539
Name: cobZ
Funciton: Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73)
Locus tag: TGAM_0538
Name: cobS
Funciton: Cobalamin-5-phosphate synthase
TGAM_0542-TGAM_0541-TGAM_0540-cobZ-cobS -41 4.8 ATGGATAAAAGCTCCAA TGAM_0542
Thermococcus kodakaraensis KOD1
Position: -42
Score: 5.05018
Sequence: ATGGATAAAAACTCCAT
Locus tag: TK0862
Name: null
Funciton: hypothetical protein
Locus tag: TK0861
Name: null
Funciton: conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71
Locus tag: TK0860
Name: null
Funciton: hypothetical protein
Locus tag: TK0859
Name: null
Funciton: hypothetical protein
Locus tag: TK0858
Name: cobZ
Funciton: Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73)
Locus tag: TK0857
Name: cobS
Funciton: Cobalamin-5-phosphate synthase
Locus tag: TK0856
Name: cobY
Funciton: Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62)
TK0862-TK0861-TK0860-TK0859-cobZ-cobS-cobY -42 5.1 ATGGATAAAAACTCCAT TK0862
Thermococcus onnurineus NA1
Position: -41
Score: 4.6169
Sequence: AAGGATAAAACATCCAA
Locus tag: TON_0681
Name: null
Funciton: hypothetical protein
Locus tag: TON_0682
Name: null
Funciton: conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71
Locus tag: TON_0683
Name: cobZ
Funciton: Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73)
Locus tag: TON_0684
Name: cobS
Funciton: Cobalamin-5-phosphate synthase
TON_0681-TON_0682-cobZ-cobS -41 4.6 AAGGATAAAACATCCAA TON_0681