Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of CblR in Pyrococcus abyssi GE5

Properties
Regulator type: Transcription factor
TF locus tag:
Regulator family:
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector:
Regulog: CblR - Thermococcales
Statistics of regulated genes:
- Genes 16
- Operons 10
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 82 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -30
Score: 4.8
Sequence: CTGGACGAATAATCCAG
Locus tag: PAB0349
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
PAB0349
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
Position: -31
Score: 5
Sequence: TTGGAGCTTTTATCCAA
Locus tag: PAB0025
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: PAB0026
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
PAB0025
cbiB
Adenosylcobinamide-phosphate synthase
PAB0026
cobD
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Position: -48
Score: 5
Sequence: TTGGATAAAAGCTCCAA
Locus tag: PAB2319
Name: cobZ
Funciton: Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73)
Locus tag: PAB3017
Name: null
Funciton: hypothetical protein
Locus tag: PAB2320
Name: cobS
Funciton: Cobalamin-5-phosphate synthase
PAB2319
cobZ
Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73)
PAB3017
hypothetical protein
PAB2320
cobS
Cobalamin-5-phosphate synthase
Position: -26
Score: 5.5
Sequence: TTGGATAAATTCTCCAG
Locus tag: PAB2398
Name: meaB
Funciton: GTP-dependent assembly of methylmalonyl-CoA mutase
Locus tag: PAB2438
Name: mceE
Funciton: Methylmalonyl-CoA epimerase (EC 5.1.99.1)
PAB2398
meaB
GTP-dependent assembly of methylmalonyl-CoA mutase
PAB2438
mceE
Methylmalonyl-CoA epimerase (EC 5.1.99.1)
Position: -81
Score: 5.3
Sequence: TTAGATAATTTATCCAA
Locus tag: PAB1800
Name: mutB_N
Funciton: Methylmalonyl-CoA mutase (EC 5.4.99.2), alpha subunit, N-terminal
PAB1800
mutB_N
Methylmalonyl-CoA mutase (EC 5.4.99.2), alpha subunit, N-terminal
Position: 58
Score: 5.5
Sequence: TTGGATTTAATATCCAA
Locus tag: PAB2337
Name: nrdD
Funciton: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
Locus tag: PAB2338
Name: nrdG
Funciton: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)
PAB2337
nrdD
Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
PAB2338
nrdG
Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)
Position: -27
Score: 5
Sequence: TTGGATAAAACCTCCAA
Locus tag: PAB2326
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
PAB2326
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Position: -19
Score: 5
Sequence: ATGGAATATTTGTCCAA
Locus tag: PAB1535
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: PAB1536
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
PAB1535
btuC
Vitamin B12 ABC transporter, permease component BtuC
PAB1536
btuD
Vitamin B12 ABC transporter, ATPase component BtuD
Position: -72
Score: 5.1
Sequence: TGGGATAATATATCCAT
Locus tag: PAB2187
Name: mutB_C
Funciton: B12 binding domain of Methylmalonyl-CoA mutase (EC 5.4.99.2)
PAB2187
mutB_C
B12 binding domain of Methylmalonyl-CoA mutase (EC 5.4.99.2)
Position: -62
Score: 5.6
Sequence: TTGGATATTTAATCCAA
Locus tag: PAB1230
Name: sucD
Funciton: Archaeal succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5)
PAB1230
sucD
Archaeal succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5)
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