Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of CblR in Thermococcus kodakaraensis KOD1

Properties
Regulator type: Transcription factor
TF locus tag:
Regulator family:
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector:
Regulog: CblR - Thermococcales
Statistics of regulated genes:
- Genes 20
- Operons 11
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 82 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -87
Score: 5.5
Sequence: CTGGACAAAATATCCAA
Locus tag: TK0328
Name: mutB_C
Funciton: B12 binding domain of Methylmalonyl-CoA mutase (EC 5.4.99.2)
TK0328
mutB_C
B12 binding domain of Methylmalonyl-CoA mutase (EC 5.4.99.2)
Position: -89
Score: 5.6
Sequence: ATGGACAATTTATCCAA
Locus tag: TK1149
Name: mutB_N
Funciton: Methylmalonyl-CoA mutase (EC 5.4.99.2), alpha subunit, N-terminal
TK1149
mutB_N
Methylmalonyl-CoA mutase (EC 5.4.99.2), alpha subunit, N-terminal
Position: -28
Score: 5.1
Sequence: CTGGAGATTATGTCCAA
Locus tag: TK2130
Name: btuR
Funciton: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
TK2130
btuR
Cob(I)alamin adenosyltransferase (EC 2.5.1.17)
Position: -198
Score: 5
Sequence: ATGGATAATTCGTCCAG
Locus tag: TK1736
Name: nrdJ
Funciton: Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1) @ intein-containing
TK1736
nrdJ
Ribonucleotide reductase of class II (coenzyme B12-dependent) (EC 1.17.4.1) @ intein-containing
Position: -20
Score: 5.1
Sequence: CTGGACAAAAAGTCCAG
Locus tag: TK2209
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: TK2208
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATPase component BtuD
TK2209
btuC
Vitamin B12 ABC transporter, permease component BtuC
TK2208
btuD
Vitamin B12 ABC transporter, ATPase component BtuD
Position: -42
Score: 5.1
Sequence: ATGGATAAAAACTCCAT
Locus tag: TK0862
Name: null
Funciton: hypothetical protein
Locus tag: TK0861
Name: null
Funciton: conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71
Locus tag: TK0860
Name: null
Funciton: hypothetical protein
Locus tag: TK0859
Name: null
Funciton: hypothetical protein
Locus tag: TK0858
Name: cobZ
Funciton: Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73)
Locus tag: TK0857
Name: cobS
Funciton: Cobalamin-5-phosphate synthase
Locus tag: TK0856
Name: cobY
Funciton: Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62)
TK0862
hypothetical protein
TK0861
conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71
TK0860
hypothetical protein
TK0859
hypothetical protein
TK0858
cobZ
Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73)
TK0857
cobS
Cobalamin-5-phosphate synthase
TK0856
cobY
Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62)
Position: -127
Score: 5.9
Sequence: TTGGATAATTTATCCAA
Position: -35
Score: 5.8
Sequence: TTGGATAAATTATCCAG
Locus tag: TK2298
Name: nrdD
Funciton: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
Locus tag: TK2299
Name: nrdG
Funciton: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)
TK2298
nrdD
Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
TK2299
nrdG
Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)
Position: -73
Score: 4.6
Sequence: TTGGCCGTTTTATCCAA
Position: -26
Score: 5
Sequence: CCGGACAAATAATCCAG
Locus tag: TK0865
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
TK0865
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
Position: -27
Score: 5
Sequence: CTGGATAAAAAGTCCAC
Locus tag: TK0853
Name: cobT
Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
TK0853
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
Position: -27
Score: 5
Sequence: CTGGATGATTAATCCAG
Locus tag: TK0329
Name: meaB
Funciton: GTP-dependent assembly of methylmalonyl-CoA mutase
Locus tag: TK0330
Name: mceE
Funciton: Methylmalonyl-CoA epimerase (EC 5.1.99.1)
TK0329
meaB
GTP-dependent assembly of methylmalonyl-CoA mutase
TK0330
mceE
Methylmalonyl-CoA epimerase (EC 5.1.99.1)
Position: -69
Score: 5.2
Sequence: ATGGATATAAAATCCAT
Locus tag: TK1880
Name: sucD
Funciton: Archaeal succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5)
TK1880
sucD
Archaeal succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5)
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