Regulon of CblR in Pyrococcus furiosus DSM 3638
| Regulator type: | Transcription factor |
| TF locus tag: | |
| Regulator family: | |
| Regulation mode: | |
| Biological process: | Cobalamin biosynthesis |
| Effector: | |
| Regulog: | CblR - Thermococcales |
| Statistics of regulated genes: | |
| - Genes | 22 |
| - Operons | 10 |
| Visualization: | |
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Allows to visualize regulon content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Thermococcales
- By trascription factor - CblR
- By pathway - Cobalamin biosynthesis
| Locus Tag | Name | Function | |
|---|---|---|---|
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Position: -26
Score: 5.5 Sequence: TTGGATAATTTCTCCAG
Locus tag: PF1947
Name: meaB Funciton: GTP-dependent assembly of methylmalonyl-CoA mutase
Locus tag: PF1948
Name: mceE Funciton: Methylmalonyl-CoA epimerase (EC 5.1.99.1) |
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meaB
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GTP-dependent assembly of methylmalonyl-CoA mutase
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mceE
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Methylmalonyl-CoA epimerase (EC 5.1.99.1)
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Position: -83
Score: 4.6 Sequence: GTGGATAAAAAAGCCAG
Locus tag: PF1477
Name: mutB_N Funciton: Methylmalonyl-CoA mutase (EC 5.4.99.2), alpha subunit, N-terminal |
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mutB_N
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Methylmalonyl-CoA mutase (EC 5.4.99.2), alpha subunit, N-terminal
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Position: -25
Score: 5.1 Sequence: TTGGATTAATTAGCCAG
Locus tag: PF0836
Name: cobS Funciton: Cobalamin-5-phosphate synthase
Locus tag: PF0837
Name: cobS Funciton: Cobalamin-5-phosphate synthase
Locus tag: PF0838
Name: null Funciton: Function Code: 16.1 Conserved Hypothetical
Locus tag: PF0839
Name: null Funciton: Function Code: 16.1 Conserved Hypothetical
Locus tag: PF0840
Name: cobY Funciton: Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62)
Locus tag: PF0841
Name: cobY Funciton: Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62)
Locus tag: PF0841.1n
Name: null Funciton: hypothetical protein |
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cobS
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Cobalamin-5-phosphate synthase
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cobS
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Cobalamin-5-phosphate synthase
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Function Code: 16.1 Conserved Hypothetical
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Function Code: 16.1 Conserved Hypothetical
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cobY
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Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62)
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cobY
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Adenosylcobinamide-phosphate guanylyltransferase CobY (EC 2.7.7.62)
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hypothetical protein
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Position: -71
Score: 5.6 Sequence: TTGGATATTTAATCCAA
Locus tag: PF0233
Name: sucD Funciton: Archaeal succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5) |
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sucD
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Archaeal succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5)
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Position: -27
Score: 5.3 Sequence: ATGGATAAAAAATCCAT
Locus tag: PF0303
Name: cobT Funciton: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
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cobT
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Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
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Position: -99
Score: 5.2 Sequence: ATGGATATTTTAGCCAA
Position: -29
Score: 5.6 Sequence: TTGGACAAAATATCCAA
Locus tag: PF1971
Name: nrdD Funciton: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
Locus tag: PF1972
Name: nrdG Funciton: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) |
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nrdD
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Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
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nrdG
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Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)
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Position: -19
Score: 4.7 Sequence: TTGGCATATTTGTCCAA
Locus tag: PF0503
Name: btuC Funciton: Vitamin B12 ABC transporter, permease component BtuC
Locus tag: PF0502
Name: btuD Funciton: Vitamin B12 ABC transporter, ATPase component BtuD |
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btuC
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Vitamin B12 ABC transporter, permease component BtuC
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btuD
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Vitamin B12 ABC transporter, ATPase component BtuD
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Position: -78
Score: 5.1 Sequence: TAGGATAAAATGTCCAA
Locus tag: PF1946
Name: mutB_C Funciton: B12 binding domain of Methylmalonyl-CoA mutase (EC 5.4.99.2) |
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mutB_C
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B12 binding domain of Methylmalonyl-CoA mutase (EC 5.4.99.2)
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Position: -19
Score: 5.1 Sequence: GCGGATAAAATATCCAA
Locus tag: PF0296
Name: cbiB Funciton: Adenosylcobinamide-phosphate synthase
Locus tag: PF0295
Name: null Funciton: conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71
Locus tag: PF0294
Name: cobZ Funciton: Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73)
Locus tag: PF0293
Name: cobD Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) |
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cbiB
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Adenosylcobinamide-phosphate synthase
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conserved hypothetical protein [Pyrococcus horikoshii]; COG2102: Predicted ATPases of PP-loop superfamily; IPR002761: Domain of unknown function DUF71
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cobZ
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Predicted alpha-ribazole-5'-phosphate phosphatase CobZ (EC 3.1.3.73)
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cobD
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L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
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Position: -72
Score: 5.6 Sequence: TTGGATTTTTTATCCAA
Position: -29
Score: 5.2 Sequence: TTGGATGATTAATCCAA
Locus tag: PF1774
Name: btuF Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF |
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btuF
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Vitamin B12 ABC transporter, B12-binding component BtuF
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |