Regulog TPP - Bifidobacteriaceae
| Regulator type: | RNA regulatory element |
| Name: | TPP |
| RFAM: | RF00059 |
| Regulation mode: | |
| Biological process: | Thiamine biosynthesis |
| Effector: | Thiamine pyrophosphate |
| Phylum: | Actinobacteria |
Member of regulog collections
- By taxonomy - Bifidobacteriaceae
- By RNA motif - TPP
- By effector - Thiamine pyrophosphate
- By pathway - Thiamine biosynthesis
| Genome | Genes | Operons |
|---|---|---|
| Bifidobacterium adolescentis ATCC 15703 | 7 | 2 |
| Bifidobacterium longum NCC2705 | 10 | 4 |
| Bifidobacterium gallicum DSM 20093 | 6 | 3 |
| Bifidobacterium dentium Bd1 | 12 | 5 |
| Bifidobacterium animalis subsp. lactis AD011 | 10 | 5 |
| Bifidobacterium angulatum DSM 20098 | 11 | 4 |
| Bifidobacterium bifidum NCIMB 41171 | 4 | 2 |
| Gardnerella vaginalis 409-05 | 11 | 5 |
| Bifidobacterium breve DSM 20213 | 8 | 4 |
| Genes | Function | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| CRON 1. | ||||||||||
| thiME |
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*
Gardnerella vaginalis 409-05 Site: position = -98 score = 57.0 sequence = AGGATGGTTCGGAGT... Gene: HMPREF0424_1158: Hydroxyethylthiazole kinase (EC 2.7.1.50) / Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
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Hydroxyethylthiazole kinase (EC 2.7.1.50) / Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
| CRON 2. | ||||||||||
| thiP |
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*
Bifidobacterium gallicum DSM 20093 Site: position = -235 score = 43.41 sequence = AACGCGACACGGGGT... Gene: BIFGAL_01225: Thiamin ABC transporter, permease protein |
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*
Bifidobacterium animalis subsp. lactis AD011 Site: position = -126 score = 50.67 sequence = GAACAGCGACACGGG... Gene: BLA_1029: Thiamin ABC transporter, permease protein |
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*
Gardnerella vaginalis 409-05 Site: position = -115 score = 53.96 sequence = GACCTCAGACACGGG... Gene: HMPREF0424_0660: Thiamin ABC transporter, permease protein |
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Thiamin ABC transporter, permease protein |
| thiB |
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Gene: BIFGAL_01226: Thiamin ABC transporter, substrate-binding component |
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Gene: BLA_1028: Thiamin ABC transporter, substrate-binding component |
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Gene: HMPREF0424_0659: Thiamin ABC transporter, substrate-binding component |
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Thiamin ABC transporter, substrate-binding component |
| thiQ |
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Gene: BIFGAL_01227: Thiamin ABC transporter, ATPase component |
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Gene: BLA_1027: Thiamin ABC transporter, ATPase component |
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Gene: HMPREF0424_0658: Thiamin ABC transporter, ATPase component |
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Thiamin ABC transporter, ATPase component |
| CRON 3. | ||||||||||
| tenA |
|
*
Bifidobacterium longum NCC2705 Site: position = -157 score = 33.31 sequence = AGGCGCATTGCAGGG... Gene: BL0804: Thiaminase II (EC 3.5.99.2) |
Gene: BIFGAL_01832: Thiaminase II (EC 3.5.99.2) |
*
Bifidobacterium dentium Bd1 Site: position = -107 score = 62.69 sequence = CGGCGTAATGCAGGG... Gene: BDP_1341: Thiaminase II (EC 3.5.99.2) |
*
Bifidobacterium animalis subsp. lactis AD011 Site: position = -89 score = 55.74 sequence = CGAAGATGCGGGGGG... Gene: BLA_1213: Thiaminase II (EC 3.5.99.2) |
*
Bifidobacterium angulatum DSM 20098 Site: position = -118 score = 56.18 sequence = GCAAATTGCAGGGGA... Gene: BIFANG_01057: Thiaminase II (EC 3.5.99.2) |
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|
*
Bifidobacterium breve DSM 20213 Site: position = -156 score = 37.95 sequence = GCGCATTGCAGGGGA... Gene: BIFBRE_01283: Thiaminase II (EC 3.5.99.2) |
Thiaminase II (EC 3.5.99.2) |
| CRON 4. | ||||||||||
| thiM |
*
Bifidobacterium adolescentis ATCC 15703 Site: position = -103 score = 59.76 sequence = TAAACATGCGGGGGT... Gene: BAD_1144: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
*
Bifidobacterium longum NCC2705 Site: position = -100 score = 59.25 sequence = CACTGTAATGCAGGG... Gene: BL0115: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
*
Bifidobacterium gallicum DSM 20093 Site: position = -117 score = 48.26 sequence = GAATCAAGCAGGGGG... Gene: BIFGAL_00330: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
*
Bifidobacterium dentium Bd1 Site: position = -103 score = 57.41 sequence = TGTACATGCAGGGGA... Gene: BDP_1597: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
*
Bifidobacterium animalis subsp. lactis AD011 Site: position = -88 score = 45.91 sequence = ACACATGTCAGGGGA... Gene: BLA_0814: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
*
Bifidobacterium angulatum DSM 20098 Site: position = -100 score = 56.75 sequence = TGTACATGCAGGGGG... Gene: BIFANG_01690: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
*
Bifidobacterium bifidum NCIMB 41171 Site: position = -102 score = 47.89 sequence = GGGCACAATGCAGGG... Gene: BbifN4_010100001942: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
|
*
Bifidobacterium breve DSM 20213 Site: position = -201 score = 58.15 sequence = CAACGTAATGCAGGG... Gene: BIFBRE_00589: Hydroxyethylthiazole kinase (EC 2.7.1.50) |
Hydroxyethylthiazole kinase (EC 2.7.1.50) |
| thiEC |
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Gene: BL0114: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Thiamin biosynthesis protein ThiC |
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Gene: BDP_1598: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Thiamin biosynthesis protein ThiC |
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Gene: BIFANG_01691: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Thiamin biosynthesis protein ThiC |
Gene: BbifN4_010100001937: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Thiamin biosynthesis protein ThiC |
*
Gardnerella vaginalis 409-05 Site: position = -102 score = 61.75 sequence = ACATTTTGCAGGGGT... Gene: HMPREF0424_0892: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Thiamin biosynthesis protein ThiC |
Gene: BIFBRE_00588: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Thiamin biosynthesis protein ThiC |
Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Thiamin biosynthesis protein ThiC |
| thiD |
Gene: BAD_1146: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: BL0113: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: BIFGAL_00331: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: BDP_1599: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: BLA_0815: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) / Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: BIFANG_01692: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Gene: BbifN4_010100001922: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
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Gene: BIFBRE_00586: Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
Phosphomethylpyrimidine kinase (EC 2.7.4.7) |
| COG0011 |
Gene: BAD_1147: Thiamin/hydroxymethyl pyrimidine-binding protein-like, putative |
Gene: BL0112: Thiamin/hydroxymethyl pyrimidine-binding protein-like, putative |
Gene: BIFGAL_00345: Thiamin/hydroxymethyl pyrimidine-binding protein-like, putative |
Gene: BDP_1600: Thiamin/hydroxymethyl pyrimidine-binding protein-like, putative |
Gene: BLA_0816: Thiamin/hydroxymethyl pyrimidine-binding protein-like, putative |
Gene: BIFANG_01693: Thiamin/hydroxymethyl pyrimidine-binding protein-like, putative |
Gene: BbifN4_010100001917: Thiamin/hydroxymethyl pyrimidine-binding protein-like, putative |
Gene: HMPREF0424_0453: Thiamin/hydroxymethyl pyrimidine-binding protein-like, putative |
Gene: BIFBRE_00585: Thiamin/hydroxymethyl pyrimidine-binding protein-like, putative |
Thiamin/hydroxymethyl pyrimidine-binding protein-like, putative |
| thiE |
Gene: BAD_1145: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
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Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) |
| CRON 5. | ||||||||||
| tenA2 |
Gene: BAD_0874: Thiaminase II (EC 3.5.99.2) |
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*
Bifidobacterium dentium Bd1 Site: position = -165 score = 55.18 sequence = CGGGCACAGACACGG... Gene: BDP_2140: Thiaminase II (EC 3.5.99.2) |
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Thiaminase II (EC 3.5.99.2) |
| CRON 6. | ||||||||||
| ykoE |
*
Bifidobacterium adolescentis ATCC 15703 Site: position = -135 score = 55.85 sequence = CAGGCGCAGACACGG... Gene: BAD_0950: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
*
Bifidobacterium longum NCC2705 Site: position = -212 score = 47.99 sequence = GGGAGTTGACACGGG... Gene: BL1071: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
*
Bifidobacterium gallicum DSM 20093 Site: position = -271 score = 51.06 sequence = CGTCAACCGACACGG... Gene: BIFGAL_01797: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
*
Bifidobacterium dentium Bd1 Site: position = -134 score = 55.9 sequence = CTGTCACAGACACGG... Gene: BDP_1328: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
*2
Bifidobacterium animalis subsp. lactis AD011 Site: position = -134 score = 57.76 sequence = TCGATGTAGACACGG... Gene: BLA_1225: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine Site: position = -146 score = 52.85 sequence = GGCATCGACACGGGA... Gene: BLA_1236: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
*
Bifidobacterium angulatum DSM 20098 Site: position = -125 score = 46.26 sequence = GGCAATGACACGGGA... Gene: BIFANG_01019: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
|
*
Gardnerella vaginalis 409-05 Site: position = -288 score = 50.1 sequence = TCAATCGACACGGGT... Gene: HMPREF0424_0412: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
*
Bifidobacterium breve DSM 20213 Site: position = -170 score = 46.26 sequence = GGAGTTGACACGGGA... Gene: BIFBRE_00957: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
| ykoD |
Gene: BAD_0949: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: BL1070: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: BIFGAL_01796: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: BDP_1327: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: BLA_1237: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
2
Bifidobacterium angulatum DSM 20098 Gene: BIFANG_01029: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine Gene: BIFANG_01020: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Gene: HMPREF0424_0414: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine / Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: BIFBRE_00958: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
| ykoC |
Gene: BAD_0948: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Gene: BL1069: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Gene: BDP_1326: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Gene: BIFANG_01021: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
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Gene: BIFBRE_00959: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine |
| CRON 7. | ||||||||||
| thiO |
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*
Gardnerella vaginalis 409-05 Site: position = -93 score = 46.84 sequence = TACGAAACGCGGGAG... Gene: HMPREF0424_1286: Glycine oxidase ThiO (EC 1.4.3.19) |
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Glycine oxidase ThiO (EC 1.4.3.19) |
| thiS |
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*
Bifidobacterium longum NCC2705 Site: position = -279 score = 47.63 sequence = AACCGTAACGAACGG... Gene: BL1055a: Sulfur carrier protein ThiS |
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*
Bifidobacterium dentium Bd1 Site: position = -440 score = 40.04 sequence = GCACAACCGAACGGG... Gene: BDP_0149: Sulfur carrier protein ThiS |
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*
Bifidobacterium angulatum DSM 20098 Site: position = -265 score = 37.48 sequence = GCACAACCGAACGGG... Gene: BIFANG_00619: Sulfur carrier protein ThiS |
*
Bifidobacterium bifidum NCIMB 41171 Site: position = -201 score = 45.5 sequence = GGCGCAACCGAACGG... Gene: BbifN4_010100006723: Sulfur carrier protein ThiS |
2
Gardnerella vaginalis 409-05 Gene: HMPREF0424_0776: Sulfur carrier protein ThiS Gene: HMPREF0424_1285: Sulfur carrier protein ThiS |
*
Bifidobacterium breve DSM 20213 Site: position = -279 score = 51.35 sequence = CGTAACGAACGGGAG... Gene: BIFBRE_00980: Sulfur carrier protein ThiS |
Sulfur carrier protein ThiS |
| thiG |
Gene: BAD_0089: Thiazole biosynthesis protein ThiG |
Gene: BL1055: Thiazole biosynthesis protein ThiG |
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Gene: BDP_0147: Thiazole biosynthesis protein ThiG |
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Gene: BIFANG_00617: Thiazole biosynthesis protein ThiG |
Gene: BbifN4_010100006718: Thiazole biosynthesis protein ThiG |
2
Gardnerella vaginalis 409-05 Gene: HMPREF0424_0778: Thiazole biosynthesis protein ThiG Gene: HMPREF0424_1284: Thiazole biosynthesis protein ThiG |
Gene: BIFBRE_00981: Thiazole biosynthesis protein ThiG |
Thiazole biosynthesis protein ThiG |
| thiF |
Gene: BAD_0090: Sulfur carrier protein adenylyltransferase ThiF |
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Gene: BDP_0148: Sulfur carrier protein adenylyltransferase ThiF |
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Gene: BIFANG_00618: Sulfur carrier protein adenylyltransferase ThiF |
|
2
Gardnerella vaginalis 409-05 Gene: HMPREF0424_0777: Sulfur carrier protein adenylyltransferase ThiF Gene: HMPREF0424_1283: Sulfur carrier protein adenylyltransferase ThiF |
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Sulfur carrier protein adenylyltransferase ThiF |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |