Statistics of regulated genes

Genome	Genes	Operons
Oenococcus oeni PSU-1	7	2
Lactobacillus reuteri JCM 1112	7	3
Lactobacillus helveticus DPC 4571
Lactobacillus fermentum IFO 3956	8	3
Lactobacillus salivarius subsp. salivarius UCC118	1	1
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	3	2
Lactobacillus acidophilus NCFM	1	1
Lactobacillus johnsonii NCC 533	3	1
Lactobacillus plantarum WCFS1	7	2
Lactobacillus casei ATCC 334	9	2
Lactobacillus brevis ATCC 367	7	2
Lactobacillus sakei subsp. sakei 23K	7	3
Pediococcus pentosaceus ATCC 25745	8	3
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	23	8
Lactobacillus rhamnosus GG	9	2

Clusters of co-Regulated Orthologous operoNs (CRONs)

Genes																Function
CRON 1.
thiT	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	* Lactobacillus salivarius subsp. salivarius UCC118 Site: position = -175 score = 65.87 sequence = ACTAGCACAAGGGGA... Gene: LSL_1668: Core component YuaJ of predicted thiamin ECF transporter	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	* Lactobacillus casei ATCC 334 Site: position = -141 score = 61.38 sequence = AACCTTCACAAAGGG... Gene: LSEI_1757: Core component YuaJ of predicted thiamin ECF transporter	Lactobacillus brevis ATCC 367	* Lactobacillus sakei subsp. sakei 23K Site: position = -146 score = 56.99 sequence = CCATCGCAAAGGGGA... Gene: LSA0968: Core component YuaJ of predicted thiamin ECF transporter	Pediococcus pentosaceus ATCC 25745	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	* Lactobacillus rhamnosus GG Site: position = -140 score = 57.51 sequence = AACCTTCACAAAGGG... Gene: LGG_01815: Core component YuaJ of predicted thiamin ECF transporter	Core component YuaJ of predicted thiamin ECF transporter
CRON 2.
LEUM_0981	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus casei ATCC 334	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -176 score = 63.04 sequence = TAAATAACTAGGGGC... Gene: LEUM_0981: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase related deacylase	Lactobacillus rhamnosus GG	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase related deacylase
LEUM_0982	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus casei ATCC 334	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0982: hypothetical protein	Lactobacillus rhamnosus GG	hypothetical protein
CRON 3.
thiX	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus casei ATCC 334	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	* Pediococcus pentosaceus ATCC 25745 Site: position = -465 score = 55.05 sequence = GATTTTGTAACAGGG... Gene: PEPE_0333: Hydroxymethylpyrimidine ABC transporter, transmembrane component	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Lactobacillus rhamnosus GG	Hydroxymethylpyrimidine ABC transporter, transmembrane component
thiY	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus casei ATCC 334	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0332: Hydroxymethylpyrimidine ABC transporter, substrate-binding component	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Lactobacillus rhamnosus GG	Hydroxymethylpyrimidine ABC transporter, substrate-binding component
thiZ	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus casei ATCC 334	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0331: Hydroxymethylpyrimidine ABC transporter, ATPase component	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Lactobacillus rhamnosus GG	Hydroxymethylpyrimidine ABC transporter, ATPase component
CRON 4.
LEUM_1455	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus casei ATCC 334	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -218 score = 64.75 sequence = ATTAACATACTAGGG... Gene: LEUM_1455: Nucleoside 2-deoxyribosyltransferase	Lactobacillus rhamnosus GG	Nucleoside 2-deoxyribosyltransferase
LEUM_1454	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus casei ATCC 334	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1454: Thymidylate synthase	Lactobacillus rhamnosus GG	Thymidylate synthase
LEUM_1453	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus casei ATCC 334	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1453: SAM-dependent methyltransferase	Lactobacillus rhamnosus GG	SAM-dependent methyltransferase
CRON 5.
ykoE	*2 Oenococcus oeni PSU-1 Site: position = -151 score = 67.31 sequence = ATACTTCTATCTGGG... Gene: OEOE_0174: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine Site: position = -251 score = 65.03 sequence = ACATCAAAATCTGGG... Gene: OEOE_1491: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	* Lactobacillus reuteri JCM 1112 Site: position = -156 score = 71.88 sequence = GAATAAATCTGGGGT... Gene: LAR_1550: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus helveticus DPC 4571	*2 Lactobacillus fermentum IFO 3956 Site: position = -168 score = 57.74 sequence = TATCTTGTCTGGGGT... Gene: LAF_1705: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine Site: position = -300 score = 74.27 sequence = CAGAATCTGTCTGGG... Gene: LAF_1533: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus salivarius subsp. salivarius UCC118	* Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Site: position = -167 score = 60.93 sequence = AAAGCCACTAGGGGA... Gene: LBUL_0454: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	* Lactobacillus acidophilus NCFM Site: position = -140 score = 63.01 sequence = TAAGTCACTAGGGGT... Gene: LBA0576: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	* Lactobacillus johnsonii NCC 533 Site: position = -142 score = 59.39 sequence = GTAAATACATCTGGG... Gene: LJ0074: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	* Lactobacillus plantarum WCFS1 Site: position = -197 score = 58.06 sequence = TTCATAGCAACTGGG... Gene: lp_0219: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	* Lactobacillus casei ATCC 334 Site: position = -245 score = 68.22 sequence = AGAAACATTTGGGGT... Gene: LSEI_0294: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	* Lactobacillus brevis ATCC 367 Site: position = -180 score = 58.1 sequence = ACATATGACTGGGGT... Gene: LVIS_1827: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	*2 Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -213 score = 60.46 sequence = AATATTTTATCTGGG... Gene: LEUM_1545: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine Site: position = -409 score = 65.88 sequence = ACACCAAAATCTGGG... Gene: LEUM_0769: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	* Lactobacillus rhamnosus GG Site: position = -289 score = 71.02 sequence = AGAAACATTTGGGGT... Gene: LGG_00363: Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Substrate-specific component YkoE of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine
ykoD	2 Oenococcus oeni PSU-1 Gene: OEOE_0173: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine Gene: OEOE_1489: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus reuteri JCM 1112 Gene: LAR_1551: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus helveticus DPC 4571 Gene: lhv_0104: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus fermentum IFO 3956 Gene: LAF_1706: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus salivarius subsp. salivarius UCC118	* Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Site: position = -118 score = 37.82 sequence = GACGAATCAACGGGG... Gene: LBUL_0126: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus acidophilus NCFM Gene: LBA0094: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus johnsonii NCC 533 Gene: LJ0073: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus plantarum WCFS1 Gene: lp_0218: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus casei ATCC 334 Gene: LSEI_0295: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus brevis ATCC 367 Gene: LVIS_1828: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	2 Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1544: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine Gene: LEUM_0767: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus rhamnosus GG Gene: LGG_00364: Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Duplicated ATPase component YkoD of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine
ykoC	2 Oenococcus oeni PSU-1 Gene: OEOE_0172: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine Gene: OEOE_1488: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus reuteri JCM 1112 Gene: LAR_1552: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus helveticus DPC 4571 Gene: lhv_0103: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus fermentum IFO 3956 Gene: LAF_1707: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 Gene: LBUL_0125: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus acidophilus NCFM Gene: LBA0093: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus johnsonii NCC 533 Gene: LJ0072: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus plantarum WCFS1 Gene: lp_0217: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus casei ATCC 334 Gene: LSEI_0296: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus brevis ATCC 367 Gene: LVIS_1829: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	2 Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_1543: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine Gene: LEUM_0766: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Lactobacillus rhamnosus GG Gene: LGG_00365: Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine	Transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine
tenA	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956 Gene: LAF_0359: Thiaminase II (EC 3.5.99.2)	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus casei ATCC 334 Gene: LSEI_0297: Thiaminase II (EC 3.5.99.2)	Lactobacillus brevis ATCC 367 Gene: LVIS_1830: Thiaminase II (EC 3.5.99.2)	* Lactobacillus sakei subsp. sakei 23K Site: position = -203 score = 60.89 sequence = AATAACGCATCTGGG... Gene: LSA1095: Thiaminase II (EC 3.5.99.2)	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0561: Thiaminase II (EC 3.5.99.2)	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -176 score = 79.24 sequence = CTGTCCACTAGGGGT... Gene: LEUM_1546: Thiaminase II (EC 3.5.99.2)	Lactobacillus rhamnosus GG Gene: LGG_00366: Thiaminase II (EC 3.5.99.2)	Thiaminase II (EC 3.5.99.2)
thiW	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956 Gene: LAF_1532: Substrate-specific component ThiW of predicted thiazole ECF transporter	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus casei ATCC 334 Gene: LSEI_0298: Substrate-specific component ThiW of predicted thiazole ECF transporter	Lactobacillus brevis ATCC 367 Gene: LVIS_2201: Substrate-specific component ThiW of predicted thiazole ECF transporter	Lactobacillus sakei subsp. sakei 23K Gene: LSA1094: Substrate-specific component ThiW of predicted thiazole ECF transporter	Pediococcus pentosaceus ATCC 25745	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0937: Substrate-specific component ThiW of predicted thiazole ECF transporter	Lactobacillus rhamnosus GG Gene: LGG_00367: Substrate-specific component ThiW of predicted thiazole ECF transporter	Substrate-specific component ThiW of predicted thiazole ECF transporter
thiM	Oenococcus oeni PSU-1	* Lactobacillus reuteri JCM 1112 Site: position = -162 score = 54.26 sequence = TATTGCATTAGGGGT... Gene: LAR_0968: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Lactobacillus helveticus DPC 4571	* Lactobacillus fermentum IFO 3956 Site: position = -282 score = 61.95 sequence = TAATAGTTGCTAGGG... Gene: LAF_0803: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	* Lactobacillus plantarum WCFS1 Site: position = -183 score = 67.44 sequence = TTAAACACTAGGGGT... Gene: lp_0113: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Lactobacillus casei ATCC 334 Gene: LSEI_0299: Hydroxyethylthiazole kinase (EC 2.7.1.50)	* Lactobacillus brevis ATCC 367 Site: position = -334 score = 64.26 sequence = ACCAAAACACTAGGG... Gene: LVIS_2099: Hydroxyethylthiazole kinase (EC 2.7.1.50)	* Lactobacillus sakei subsp. sakei 23K Site: position = -178 score = 69.43 sequence = CGCTTTGCACTAGGG... Gene: LSA0059: Hydroxyethylthiazole kinase (EC 2.7.1.50)	* Pediococcus pentosaceus ATCC 25745 Site: position = -185 score = 66.6 sequence = ATCTGCACTAGGGGT... Gene: PEPE_0558: Hydroxyethylthiazole kinase (EC 2.7.1.50)	*2 Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0938: Hydroxyethylthiazole kinase (EC 2.7.1.50) Site: position = -234 score = 60.02 sequence = ATAAATATCTGGGGT... Gene: LEUM_0485: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Lactobacillus rhamnosus GG Gene: LGG_00368: Hydroxyethylthiazole kinase (EC 2.7.1.50)	Hydroxyethylthiazole kinase (EC 2.7.1.50)
thiE	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112 Gene: LAR_0970: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956 Gene: LAF_0801: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_0115: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Lactobacillus casei ATCC 334 Gene: LSEI_0300: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Lactobacillus brevis ATCC 367 Gene: LVIS_2097: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Lactobacillus sakei subsp. sakei 23K Gene: LSA0057: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0560: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	*2 Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -223 score = 64.25 sequence = ATATGTATGTCTGGG... Gene: LEUM_1159: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3) Gene: LEUM_0487: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Lactobacillus rhamnosus GG Gene: LGG_00369: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)	Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
thiD	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112 Gene: LAR_0969: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956 Gene: LAF_0802: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_0114: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Lactobacillus casei ATCC 334 Gene: LSEI_0301: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Lactobacillus brevis ATCC 367 Gene: LVIS_2098: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Lactobacillus sakei subsp. sakei 23K Gene: LSA0058: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Pediococcus pentosaceus ATCC 25745 Gene: PEPE_0559: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0486: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Lactobacillus rhamnosus GG Gene: LGG_00370: Phosphomethylpyrimidine kinase (EC 2.7.4.7)	Phosphomethylpyrimidine kinase (EC 2.7.4.7)
LEUM_0933	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus casei ATCC 334	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	* Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Site: position = -349 score = 65.35 sequence = GCTTGTGCTAGGGGC... Site: position = -177 score = 79.87 sequence = ATAATCACTAGGGGC... Gene: LEUM_0933: Xanthine/uracil permease	Lactobacillus rhamnosus GG	Xanthine/uracil permease
LEUM_0934	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus casei ATCC 334	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0934: Acyl-CoA synthetase (AMP-forming)/AMP-acid ligse II	Lactobacillus rhamnosus GG	Acyl-CoA synthetase (AMP-forming)/AMP-acid ligse II
LEUM_0935	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus casei ATCC 334	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0935: Acyl-CoA reductase (LuxC)	Lactobacillus rhamnosus GG	Acyl-CoA reductase (LuxC)
LEUM_0936	Oenococcus oeni PSU-1	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus casei ATCC 334	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	Pediococcus pentosaceus ATCC 25745	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0936: 3-oxoacyl-acyl carrier protein reductase	Lactobacillus rhamnosus GG	3-oxoacyl-acyl carrier protein reductase
cytX	Oenococcus oeni PSU-1	* Lactobacillus reuteri JCM 1112 Site: position = -182 score = 59.27 sequence = TTGCATAAACGGGGA... Gene: LAR_1494: Predicted hydroxymethylpyrimidine transporter CytX	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1 Gene: lp_0116: Predicted hydroxymethylpyrimidine transporter CytX	Lactobacillus casei ATCC 334	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K Gene: LSA0055: Predicted hydroxymethylpyrimidine transporter CytX	Pediococcus pentosaceus ATCC 25745	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	Lactobacillus rhamnosus GG	Predicted hydroxymethylpyrimidine transporter CytX
LEUM_0768	Oenococcus oeni PSU-1 Gene: OEOE_1490: hypothetical protein	Lactobacillus reuteri JCM 1112	Lactobacillus helveticus DPC 4571	Lactobacillus fermentum IFO 3956	Lactobacillus salivarius subsp. salivarius UCC118	Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	Lactobacillus acidophilus NCFM	Lactobacillus johnsonii NCC 533	Lactobacillus plantarum WCFS1	Lactobacillus casei ATCC 334 Gene: LSEI_0169: hypothetical protein	Lactobacillus brevis ATCC 367	Lactobacillus sakei subsp. sakei 23K	* Pediococcus pentosaceus ATCC 25745 Site: position = -206 score = 55.05 sequence = GATTTTGTAACAGGG... Gene: PEPE_0334: hypothetical protein	Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 Gene: LEUM_0768: hypothetical protein	Lactobacillus rhamnosus GG	hypothetical protein

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