Regulog Cobalamin - Bacteroidaceae

Properties
Regulator type:	RNA regulatory element
Name:	Cobalamin
RFAM:	RF00174
Regulation mode:
Biological process:	Cobalamin biosynthesis
Effector:	Adenosylcobalamin
Phylum:	Bacteroidetes

Member of regulog collections

By taxonomy - Bacteroidaceae
By RNA motif - Cobalamin
By effector - Adenosylcobalamin
By pathway - Cobalamin biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Bacteroides thetaiotaomicron VPI-5482	22	6
Bacteroides ovatus ATCC 8483	25	7
Bacteroides fragilis NCTC 9343	29	7
Bacteroides stercoris ATCC 43183	22	5
Bacteroides eggerthii DSM 20697	14	3
Bacteroides uniformis ATCC 8492	26	5
Bacteroides cellulosilyticus DSM 14838	26	8
Bacteroides vulgatus ATCC 8482	21	9
Bacteroides dorei DSM 17855	18	8
Bacteroides coprophilus DSM 18228	15	3
Bacteroides plebeius DSM 17135	21	4

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes												Function

CRON 1.
BT1957	* Bacteroides thetaiotaomicron VPI-5482 Site: position = -348 score = 109.96 sequence = AATTTTGCAGTCGGG... Gene: BT1957: Hypothetical protein	* Bacteroides ovatus ATCC 8483 Site: position = -352 score = 102.52 sequence = CTTAACTTTGCACCA... Gene: BACOVA_04709: Hypothetical protein	Bacteroides fragilis NCTC 9343	* Bacteroides stercoris ATCC 43183 Site: position = -348 score = 109.96 sequence = AATTTTGCAGTCGGG... Gene: BACSTE_00799: Hypothetical protein	* Bacteroides eggerthii DSM 20697 Site: position = -346 score = 109.96 sequence = TTTTGCAGTCGGGAA... Gene: BACEGG_00933: Hypothetical protein	* Bacteroides uniformis ATCC 8492 Site: position = -336 score = 109.96 sequence = AATTTTGCAGTCGGG... Gene: BACUNI_02897: Hypothetical protein	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	* Bacteroides coprophilus DSM 18228 Site: position = -344 score = 106.35 sequence = TTTTTGTAATTGGAA... Gene: BACCOPRO_02029: Hypothetical protein	* Bacteroides plebeius DSM 17135 Site: position = -345 score = 102.58 sequence = TTTTGCAATCAGGAA... Gene: BACPLE_02584: Hypothetical protein	Hypothetical protein
BT1956	Bacteroides thetaiotaomicron VPI-5482 Gene: BT1956: Putative cell surface protein	Bacteroides ovatus ATCC 8483 Gene: BACOVA_04708: Putative cell surface protein	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00798: Putative cell surface protein	Bacteroides eggerthii DSM 20697 Gene: BACEGG_00934: Putative cell surface protein	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02896: Putative cell surface protein	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228 Gene: BACCOPRO_02030: Putative cell surface protein	2 Bacteroides plebeius DSM 17135 Gene: BACPLE_02586: Putative cell surface protein Gene: BACPLE_02585: Putative cell surface protein	Putative cell surface protein
BT1955	Bacteroides thetaiotaomicron VPI-5482 Gene: BT1955: Putative cell wall biogenesis protein secretory protein	Bacteroides ovatus ATCC 8483 Gene: BACOVA_04707: Putative cell wall biogenesis protein secretory protein	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00797: Putative cell wall biogenesis protein secretory protein	Bacteroides eggerthii DSM 20697 Gene: BACEGG_00935: Putative cell wall biogenesis protein secretory protein	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02895: Putative cell wall biogenesis protein secretory protein	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228 Gene: BACCOPRO_02031: Putative cell wall biogenesis protein secretory protein	Bacteroides plebeius DSM 17135 Gene: BACPLE_02587: Putative cell wall biogenesis protein secretory protein	Putative cell wall biogenesis protein secretory protein
BT1954	2 Bacteroides thetaiotaomicron VPI-5482* Gene: BT1954: Putative surface layer protein secretory protein Site: position = -394 score = 97.46 sequence = AGTATCTTTGCACCT... Gene: BT2095: Putative surface layer protein secretory protein	Bacteroides ovatus ATCC 8483 Gene: BACOVA_04706: Putative surface layer protein secretory protein	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00796: Putative surface layer protein secretory protein	Bacteroides eggerthii DSM 20697 Gene: BACEGG_00936: Putative surface layer protein secretory protein	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02894: Putative surface layer protein secretory protein	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228 Gene: BACCOPRO_02032: Putative surface layer protein secretory protein	Bacteroides plebeius DSM 17135 Gene: BACPLE_02588: Putative surface layer protein secretory protein	Putative surface layer protein secretory protein
btuB2	2 Bacteroides thetaiotaomicron VPI-5482 Gene: BT1953: Outer membrane vitamin B12 receptor BtuB Gene: BT2094: Outer membrane vitamin B12 receptor BtuB	Bacteroides ovatus ATCC 8483 Gene: BACOVA_04705: Outer membrane vitamin B12 receptor BtuB	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00795: Outer membrane vitamin B12 receptor BtuB	Bacteroides eggerthii DSM 20697 Gene: BACEGG_00937: Outer membrane vitamin B12 receptor BtuB	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02893: Outer membrane vitamin B12 receptor BtuB	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228 Gene: BACCOPRO_02034: Outer membrane vitamin B12 receptor BtuB	Bacteroides plebeius DSM 17135 Gene: BACPLE_02589: Outer membrane vitamin B12 receptor BtuB	Outer membrane vitamin B12 receptor BtuB
btuF2	Bacteroides thetaiotaomicron VPI-5482 Gene: BT1952: Vitamin B12 ABC transporter, B12-binding component BtuF1	Bacteroides ovatus ATCC 8483 Gene: BACOVA_04704: Vitamin B12 ABC transporter, B12-binding component BtuF1	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00794: Vitamin B12 ABC transporter, B12-binding component BtuF1	Bacteroides eggerthii DSM 20697 Gene: BACEGG_00938: Vitamin B12 ABC transporter, B12-binding component BtuF1	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02892: Vitamin B12 ABC transporter, B12-binding component BtuF1	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228 Gene: BACCOPRO_02035: Vitamin B12 ABC transporter, B12-binding component BtuF1	Bacteroides plebeius DSM 17135 Gene: BACPLE_02590: Vitamin B12 ABC transporter, B12-binding component BtuF1	Vitamin B12 ABC transporter, B12-binding component BtuF1
btuC2	Bacteroides thetaiotaomicron VPI-5482 Gene: BT1951: Vitamin B12 ABC transporter, permease component BtuC1	Bacteroides ovatus ATCC 8483 Gene: BACOVA_04703: Vitamin B12 ABC transporter, permease component BtuC1	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00793: Vitamin B12 ABC transporter, permease component BtuC1	Bacteroides eggerthii DSM 20697 Gene: BACEGG_00939: Vitamin B12 ABC transporter, permease component BtuC1	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02891: Vitamin B12 ABC transporter, permease component BtuC1	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228 Gene: BACCOPRO_02036: Vitamin B12 ABC transporter, permease component BtuC1	Bacteroides plebeius DSM 17135 Gene: BACPLE_02591: Vitamin B12 ABC transporter, permease component BtuC1	Vitamin B12 ABC transporter, permease component BtuC1
btuD2	Bacteroides thetaiotaomicron VPI-5482 Gene: BT1950: Vitamin B12 ABC transporter, ATPase component	Bacteroides ovatus ATCC 8483 Gene: BACOVA_04702: Vitamin B12 ABC transporter, ATPase component	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00792: Vitamin B12 ABC transporter, ATPase component	Bacteroides eggerthii DSM 20697 Gene: BACEGG_00940: Vitamin B12 ABC transporter, ATPase component	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02890: Vitamin B12 ABC transporter, ATPase component	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228 Gene: BACCOPRO_02038: Vitamin B12 ABC transporter, ATPase component	Bacteroides plebeius DSM 17135 Gene: BACPLE_02592: Vitamin B12 ABC transporter, ATPase component	Vitamin B12 ABC transporter, ATPase component
BT0975	Bacteroides thetaiotaomicron VPI-5482 Gene: BT0975: Putative membrane protein	2 Bacteroides ovatus ATCC 8483 Gene: BACOVA_04701: Putative membrane protein Gene: BACOVA_00781: Putative membrane protein	2 Bacteroides fragilis NCTC 9343 Gene: BF2716: Putative membrane protein Gene: BF2537: Putative membrane protein	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04108: Putative membrane protein	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Putative membrane protein
BT0974	Bacteroides thetaiotaomicron VPI-5482 Gene: BT0974: Probable integral membrane protein	2 Bacteroides ovatus ATCC 8483 Gene: BACOVA_04700: Probable integral membrane protein Gene: BACOVA_00780: Probable integral membrane protein	2 Bacteroides fragilis NCTC 9343 Gene: BF2717: Probable integral membrane protein Gene: BF2536: Probable integral membrane protein	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04109: Probable integral membrane protein	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Probable integral membrane protein
BT1949	Bacteroides thetaiotaomicron VPI-5482 Gene: BT1949: Hypothetical protein	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00791: Hypothetical protein	Bacteroides eggerthii DSM 20697 Gene: BACEGG_00941: Hypothetical protein	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02889: Hypothetical protein	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Hypothetical protein
BACCOPRO_02033	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228 Gene: BACCOPRO_02033: Transposase	Bacteroides plebeius DSM 17135	Transposase
cbtD	Bacteroides thetaiotaomicron VPI-5482	* Bacteroides ovatus ATCC 8483 Site: position = -425 score = 93.55 sequence = CTATCTTTGCCCCTG... Gene: BACOVA_03267: Predicted cobalt transporter in Bacteroides_Porphyromonas	* Bacteroides fragilis NCTC 9343 Site: position = -561 score = 92.95 sequence = CTTATCTTTGTCCCG... Gene: BF2538: Predicted cobalt transporter in Bacteroides_Porphyromonas	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02908: Predicted cobalt transporter in Bacteroides_Porphyromonas	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_00559: Predicted cobalt transporter in Bacteroides_Porphyromonas	2 Bacteroides vulgatus ATCC 8482 Gene: BVU_3101: Predicted cobalt transporter in Bacteroides_Porphyromonas Gene: BVU_3112: Predicted cobalt transporter in Bacteroides_Porphyromonas	2 Bacteroides dorei DSM 17855 Gene: BACDOR_02867: Predicted cobalt transporter in Bacteroides_Porphyromonas Gene: BACDOR_02875: Predicted cobalt transporter in Bacteroides_Porphyromonas	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Predicted cobalt transporter in Bacteroides_Porphyromonas
BT0973	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343 Gene: BF2535: Hypothetical protein	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Hypothetical protein
cbiA	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343 Gene: BF2534: Cobyrinic acid A,C-diamide synthase	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00629: Cobyrinic acid A,C-diamide synthase	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02905: Cobyrinic acid A,C-diamide synthase	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04603: Cobyrinic acid A,C-diamide synthase	Bacteroides vulgatus ATCC 8482 Gene: BVU_3113: Cobyrinic acid A,C-diamide synthase	Bacteroides dorei DSM 17855 Gene: BACDOR_02866: Cobyrinic acid A,C-diamide synthase	Bacteroides coprophilus DSM 18228 Gene: BACCOPRO_01734: Cobyrinic acid A,C-diamide synthase	Bacteroides plebeius DSM 17135	Cobyrinic acid A,C-diamide synthase
pduO	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343 Gene: BF2533: Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17)	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00628: Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17)	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02852: Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17)	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04604: Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17)	Bacteroides vulgatus ATCC 8482 Gene: BVU_3114: Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17)	Bacteroides dorei DSM 17855 Gene: BACDOR_02865: Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17)	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17)
pccC	* Bacteroides thetaiotaomicron VPI-5482 Site: position = -341 score = 86.48 sequence = TCTTTGCCCCCCGAA... Gene: BT1915: Biotin carboxylase of propionyl-CoA carboxylase (EC 6.3.4.14)	* Bacteroides ovatus ATCC 8483 Site: position = -316 score = 90.46 sequence = TATCTTTGCCCCCCG... Gene: BACOVA_01465: Biotin carboxylase of propionyl-CoA carboxylase (EC 6.3.4.14)	* Bacteroides fragilis NCTC 9343 Site: position = -356 score = 86.52 sequence = ATATTTGTCGCCGAA... Gene: BF3337: Biotin carboxylase of propionyl-CoA carboxylase (EC 6.3.4.14)	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	* Bacteroides uniformis ATCC 8492 Site: position = -341 score = 99.24 sequence = TTATCTTTGCCCGCG... Gene: BACUNI_02911: Biotin carboxylase of propionyl-CoA carboxylase (EC 6.3.4.14)	* Bacteroides cellulosilyticus DSM 14838 Site: position = -494 score = 90.51 sequence = ACTATCTTTGCCCCG... Gene: BACCELL_00563: Biotin carboxylase of propionyl-CoA carboxylase (EC 6.3.4.14)	* Bacteroides vulgatus ATCC 8482 Site: position = -488 score = 101.35 sequence = ATTATCTTTGCCCCG... Gene: BVU_3104: Biotin carboxylase of propionyl-CoA carboxylase (EC 6.3.4.14)	Bacteroides dorei DSM 17855 Gene: BACDOR_05015: Biotin carboxylase of propionyl-CoA carboxylase (EC 6.3.4.14)	Bacteroides coprophilus DSM 18228 Gene: BACCOPRO_02972: Biotin carboxylase of propionyl-CoA carboxylase (EC 6.3.4.14)	Bacteroides plebeius DSM 17135 Gene: BACPLE_01898: Biotin carboxylase of propionyl-CoA carboxylase (EC 6.3.4.14)	Biotin carboxylase of propionyl-CoA carboxylase (EC 6.3.4.14)
pccA	Bacteroides thetaiotaomicron VPI-5482 Gene: BT1916: Biotin carboxyl carrier protein of propionyl-CoA carboxylase	Bacteroides ovatus ATCC 8483 Gene: BACOVA_01464: Biotin carboxyl carrier protein of propionyl-CoA carboxylase	Bacteroides fragilis NCTC 9343 Gene: BF3338: Biotin carboxyl carrier protein of propionyl-CoA carboxylase	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02910: Biotin carboxyl carrier protein of propionyl-CoA carboxylase	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_00562: Biotin carboxyl carrier protein of propionyl-CoA carboxylase	Bacteroides vulgatus ATCC 8482 Gene: BVU_3103: Biotin carboxyl carrier protein of propionyl-CoA carboxylase	Bacteroides dorei DSM 17855 Gene: BACDOR_05014: Biotin carboxyl carrier protein of propionyl-CoA carboxylase	Bacteroides coprophilus DSM 18228 Gene: BACCOPRO_02973: Biotin carboxyl carrier protein of propionyl-CoA carboxylase	Bacteroides plebeius DSM 17135 Gene: BACPLE_01899: Biotin carboxyl carrier protein of propionyl-CoA carboxylase	Biotin carboxyl carrier protein of propionyl-CoA carboxylase
pccB	Bacteroides thetaiotaomicron VPI-5482 Gene: BT1917: Propionyl-CoA carboxylase beta chain (EC 6.4.1.3)	Bacteroides ovatus ATCC 8483 Gene: BACOVA_01463: Propionyl-CoA carboxylase beta chain (EC 6.4.1.3)	Bacteroides fragilis NCTC 9343 Gene: BF3339: Propionyl-CoA carboxylase beta chain (EC 6.4.1.3)	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02909: Propionyl-CoA carboxylase beta chain (EC 6.4.1.3)	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_00561: Propionyl-CoA carboxylase beta chain (EC 6.4.1.3)	Bacteroides vulgatus ATCC 8482 Gene: BVU_3102: Propionyl-CoA carboxylase beta chain (EC 6.4.1.3)	Bacteroides dorei DSM 17855 Gene: BACDOR_05013: Propionyl-CoA carboxylase beta chain (EC 6.4.1.3)	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Propionyl-CoA carboxylase beta chain (EC 6.4.1.3)

CRON 2.
btuB1	* Bacteroides thetaiotaomicron VPI-5482 Site: position = -387 score = 104.15 sequence = TATCTTTGTCGCGCA... Gene: BT1489: Outer membrane vitamin B12 receptor BtuB	2 Bacteroides ovatus ATCC 8483* Site: position = -382 score = 96.96 sequence = TATCTTTGTCGCGCA... Gene: BACOVA_04219: Outer membrane vitamin B12 receptor BtuB Site: position = -536 score = 85.52 sequence = TCTAACTTTGTGCCA... Gene: BACOVA_03265: Outer membrane vitamin B12 receptor BtuB	* Bacteroides fragilis NCTC 9343 Site: position = -379 score = 100.57 sequence = TTTATCTTTGCAGTG... Gene: BF1583: Outer membrane vitamin B12 receptor BtuB	* Bacteroides stercoris ATCC 43183 Site: position = -258 score = 100.85 sequence = CCTATCTTTGCCGGC... Gene: BACSTE_00919: Outer membrane vitamin B12 receptor BtuB	* Bacteroides eggerthii DSM 20697 Site: position = -255 score = 107.07 sequence = TTATCTTTGCGGCGT... Gene: BACEGG_02215: Outer membrane vitamin B12 receptor BtuB	* Bacteroides uniformis ATCC 8492 Site: position = -100 score = 103.53 sequence = CCTATCTTTGTCCAC... Gene: BACUNI_04579: Outer membrane vitamin B12 receptor BtuB	2 Bacteroides cellulosilyticus DSM 14838* Site: position = -203 score = 97.1 sequence = TATCTTTGCCCTTCG... Gene: BACCELL_01030: Outer membrane vitamin B12 receptor BtuB Site: position = -356 score = 98.07 sequence = TATCTTTGCCATTGA... Gene: BACCELL_01617: Outer membrane vitamin B12 receptor BtuB	* Bacteroides vulgatus ATCC 8482 Site: position = -293 score = 86.31 sequence = AACTATCTTTGCCAT... Gene: BVU_2057: Outer membrane vitamin B12 receptor BtuB	* Bacteroides dorei DSM 17855 Site: position = -294 score = 84.95 sequence = AACTATCTTTGCCAC... Gene: BACDOR_03419: Outer membrane vitamin B12 receptor BtuB	* Bacteroides coprophilus DSM 18228 Site: position = -272 score = 92.82 sequence = TCCTACCTTTGCGAA... Gene: BACCOPRO_03547: Outer membrane vitamin B12 receptor BtuB	2 Bacteroides plebeius DSM 17135* Site: position = -276 score = 94.17 sequence = ATGTATATTTGCAAT... Gene: BACPLE_03025: Outer membrane vitamin B12 receptor BtuB Site: position = -259 score = 105.57 sequence = TTACCTTTGCCCTCA... Gene: BACPLE_00041: Outer membrane vitamin B12 receptor BtuB	Outer membrane vitamin B12 receptor BtuB
BACPLE_03024	2 Bacteroides thetaiotaomicron VPI-5482* Site: position = -286 score = 102.58 sequence = ATCTTTGTCCCCGCA... Gene: BT1486: Hypothetical protein Gene: BT1487: Hypothetical protein	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343 Gene: BF1581: Hypothetical protein	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00918: Hypothetical protein	Bacteroides eggerthii DSM 20697 Gene: BACEGG_02216: Hypothetical protein	Bacteroides uniformis ATCC 8492 Gene: BACUNI_04578: Hypothetical protein	2 Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_01029: Hypothetical protein Gene: BACCELL_01616: Hypothetical protein	Bacteroides vulgatus ATCC 8482 Gene: BVU_2056: Hypothetical protein	Bacteroides dorei DSM 17855 Gene: BACDOR_03418: Hypothetical protein	Bacteroides coprophilus DSM 18228 Gene: BACCOPRO_03546: Hypothetical protein	Bacteroides plebeius DSM 17135 Gene: BACPLE_03024: Hypothetical protein	Hypothetical protein
BACDOR_03417	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855 Gene: BACDOR_03417: Predicted ATP-binding protein	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Predicted ATP-binding protein
btuF1	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00917: Vitamin B12 ABC transporter, B12-binding component BtuF1	Bacteroides eggerthii DSM 20697 Gene: BACEGG_02217: Vitamin B12 ABC transporter, B12-binding component BtuF1	Bacteroides uniformis ATCC 8492 Gene: BACUNI_04576: Vitamin B12 ABC transporter, B12-binding component BtuF1	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_01028: Vitamin B12 ABC transporter, B12-binding component BtuF1	Bacteroides vulgatus ATCC 8482 Gene: BVU_2055: Vitamin B12 ABC transporter, B12-binding component BtuF1	Bacteroides dorei DSM 17855 Gene: BACDOR_03416: Vitamin B12 ABC transporter, B12-binding component BtuF1	Bacteroides coprophilus DSM 18228 Gene: BACCOPRO_03545: Vitamin B12 ABC transporter, B12-binding component BtuF1	Bacteroides plebeius DSM 17135 Gene: BACPLE_03023: Vitamin B12 ABC transporter, B12-binding component BtuF1	Vitamin B12 ABC transporter, B12-binding component BtuF1
btuC1	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00916: Vitamin B12 ABC transporter, permease component BtuC1	Bacteroides eggerthii DSM 20697 Gene: BACEGG_02218: Vitamin B12 ABC transporter, permease component BtuC1	Bacteroides uniformis ATCC 8492 Gene: BACUNI_04575: Vitamin B12 ABC transporter, permease component BtuC1	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_01027: Vitamin B12 ABC transporter, permease component BtuC1	Bacteroides vulgatus ATCC 8482 Gene: BVU_2054: Vitamin B12 ABC transporter, permease component BtuC1	Bacteroides dorei DSM 17855 Gene: BACDOR_03415: Vitamin B12 ABC transporter, permease component BtuC1	Bacteroides coprophilus DSM 18228 Gene: BACCOPRO_03544: Vitamin B12 ABC transporter, permease component BtuC1	Bacteroides plebeius DSM 17135 Gene: BACPLE_03022: Vitamin B12 ABC transporter, permease component BtuC1	Vitamin B12 ABC transporter, permease component BtuC1
btuD1	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_01026: Putative vitamin B12 ABC transporter, ATP-binding protein	Bacteroides vulgatus ATCC 8482 Gene: BVU_2053: Putative vitamin B12 ABC transporter, ATP-binding protein	Bacteroides dorei DSM 17855 Gene: BACDOR_03414: Putative vitamin B12 ABC transporter, ATP-binding protein	Bacteroides coprophilus DSM 18228 Gene: BACCOPRO_03543: Putative vitamin B12 ABC transporter, ATP-binding protein	Bacteroides plebeius DSM 17135 Gene: BACPLE_03021: Putative vitamin B12 ABC transporter, ATP-binding protein	Putative vitamin B12 ABC transporter, ATP-binding protein
BT1488	Bacteroides thetaiotaomicron VPI-5482 Gene: BT1488: Putative cell surface protein	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_01615: Putative cell surface protein	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Putative cell surface protein
BACCELL_01613	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	2 Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_01613: Hypothetical protein Gene: BACCELL_01614: Hypothetical protein	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Hypothetical protein
BACPLE_00040	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483 Gene: BACOVA_03264: Hypothetical protein	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135 Gene: BACPLE_00040: Hypothetical protein	Hypothetical protein
BT1490	Bacteroides thetaiotaomicron VPI-5482 Gene: BT1490: Hypothetical protein	Bacteroides ovatus ATCC 8483 Gene: BACOVA_04220: Hypothetical protein	Bacteroides fragilis NCTC 9343 Gene: BF1582: Hypothetical protein	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135 Gene: BACPLE_00039: Hypothetical protein	Hypothetical protein
BACPLE_00038	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135 Gene: BACPLE_00038: Hypothetical protein	Hypothetical protein
BACPLE_00037	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135 Gene: BACPLE_00037: Hypothetical protein	Hypothetical protein
BACOVA_03263	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483 Gene: BACOVA_03263: Hypothetical protein	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Hypothetical protein
BACOVA_03262	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483 Gene: BACOVA_03262: Putative cell surface protein	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Putative cell surface protein
BT1491	Bacteroides thetaiotaomicron VPI-5482 Gene: BT1491: Hypothetical protein	Bacteroides ovatus ATCC 8483 Gene: BACOVA_04221: Hypothetical protein	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Hypothetical protein

CRON 3.
btuB4	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	* Bacteroides fragilis NCTC 9343 Site: position = -302 score = 74.1 sequence = ATATTTGCAGCCGCT... Gene: BF2539: B12-regulated TonB-dependent outer membrane receptor	* Bacteroides stercoris ATCC 43183 Site: position = -337 score = 74.07 sequence = ATATTTGTCACCGCT... Gene: BACSTE_00635: B12-regulated TonB-dependent outer membrane receptor	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02921: B12-regulated TonB-dependent outer membrane receptor	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04583: B12-regulated TonB-dependent outer membrane receptor	2 Bacteroides vulgatus ATCC 8482* Site: position = -258 score = 85.76 sequence = CTACCTTTGCATCAG... Gene: BVU_3092: B12-regulated TonB-dependent outer membrane receptor Site: position = -260 score = 87.39 sequence = CTACCTTTGTGCCCG... Gene: BVU_3110: B12-regulated TonB-dependent outer membrane receptor	2 Bacteroides dorei DSM 17855* Site: position = -257 score = 84.16 sequence = ACCTTTGCATCAGAT... Gene: BACDOR_02883: B12-regulated TonB-dependent outer membrane receptor Site: position = -259 score = 88.76 sequence = ACCTTTGCGCCCGGT... Gene: BACDOR_02868: B12-regulated TonB-dependent outer membrane receptor	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	B12-regulated TonB-dependent outer membrane receptor
cbiK	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343 Gene: BF2540: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00636: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Bacteroides eggerthii DSM 20697	2 Bacteroides uniformis ATCC 8492 Gene: BACUNI_02915: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) Gene: BACUNI_02922: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	2 Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04581: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3) Gene: BACCELL_04589: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
btuB	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343 Gene: BF2541: Outer membrane vitamin B12 receptor BtuB	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Outer membrane vitamin B12 receptor BtuB
btuN	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343 Gene: BF2542: Optional hypothetical component of the B12 transporter BtuN	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02916: Optional hypothetical component of the B12 transporter BtuN	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04588: Optional hypothetical component of the B12 transporter BtuN	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Optional hypothetical component of the B12 transporter BtuN
btuS	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343 Gene: BF2543: B12-related chelatase BtuS	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02917: B12-related chelatase BtuS	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04587: B12-related chelatase BtuS	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	B12-related chelatase BtuS
btuV	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343 Gene: BF2544: Predicted component of B12-related transporter	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02918: Predicted component of B12-related transporter	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04586: Predicted component of B12-related transporter	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Predicted component of B12-related transporter
btuT	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343 Gene: BF2545: Hypothetical transporter BtuT for various metalloporphyrins	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02919: Hypothetical transporter BtuT for various metalloporphyrins	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04585: Hypothetical transporter BtuT for various metalloporphyrins	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Hypothetical transporter BtuT for various metalloporphyrins
btuU	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343 Gene: BF2546: Predicted component of B12-related transporter	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02920: Predicted component of B12-related transporter	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04584: Predicted component of B12-related transporter	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Predicted component of B12-related transporter
cbiHC	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343 Gene: BF2547: Cobalt-precorrin-3b C17-methyltransferase / Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00637: Cobalt-precorrin-3b C17-methyltransferase / Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02924: Cobalt-precorrin-3b C17-methyltransferase / Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04580: Cobalt-precorrin-3b C17-methyltransferase / Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Bacteroides vulgatus ATCC 8482 Gene: BVU_3083: Cobalt-precorrin-3b C17-methyltransferase / Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Bacteroides dorei DSM 17855 Gene: BACDOR_02892: Cobalt-precorrin-3b C17-methyltransferase / Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Cobalt-precorrin-3b C17-methyltransferase / Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
cbiET	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343 Gene: BF2548: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00638: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02926: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04579: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Bacteroides vulgatus ATCC 8482 Gene: BVU_3082: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Bacteroides dorei DSM 17855 Gene: BACDOR_02893: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
cbiGF	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343 Gene: BF2549: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00639: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02929: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04578: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Bacteroides vulgatus ATCC 8482 Gene: BVU_3081: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Bacteroides dorei DSM 17855 Gene: BACDOR_02894: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
cbiJD	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343 Gene: BF2550: Cobalt-precorrin-6x reductase (EC 1.3.1.54) / Cobalt-precorrin-6 synthase, anaerobic	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00640: Cobalt-precorrin-6x reductase (EC 1.3.1.54) / Cobalt-precorrin-6 synthase, anaerobic	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02930: Cobalt-precorrin-6x reductase (EC 1.3.1.54) / Cobalt-precorrin-6 synthase, anaerobic	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04577: Cobalt-precorrin-6x reductase (EC 1.3.1.54) / Cobalt-precorrin-6 synthase, anaerobic	Bacteroides vulgatus ATCC 8482 Gene: BVU_3080: Cobalt-precorrin-6x reductase (EC 1.3.1.54) / Cobalt-precorrin-6 synthase, anaerobic	Bacteroides dorei DSM 17855 Gene: BACDOR_02895: Cobalt-precorrin-6x reductase (EC 1.3.1.54) / Cobalt-precorrin-6 synthase, anaerobic	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Cobalt-precorrin-6x reductase (EC 1.3.1.54) / Cobalt-precorrin-6 synthase, anaerobic
btuB3	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	* Bacteroides uniformis ATCC 8492 Site: position = -329 score = 99.43 sequence = ATCTTTGTCCCAGTT... Gene: BACUNI_02913: Outer membrane vitamin B12 receptor BtuB	* Bacteroides cellulosilyticus DSM 14838 Site: position = -336 score = 92.1 sequence = ATATCTTTGCAGCGT... Gene: BACCELL_04591: Outer membrane vitamin B12 receptor BtuB	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Outer membrane vitamin B12 receptor BtuB
BACCELL_04590	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492 Gene: BACUNI_02914: Hypothetical protein	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04590: Hypothetical protein	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Hypothetical protein
btuF1	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482 Gene: BVU_3091: Vitamin B12 ABC transporter, B12-binding component BtuF1	Bacteroides dorei DSM 17855 Gene: BACDOR_02884: Vitamin B12 ABC transporter, B12-binding component BtuF1	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Vitamin B12 ABC transporter, B12-binding component BtuF1

CRON 4.
nrdD	* Bacteroides thetaiotaomicron VPI-5482 Site: position = -214 score = 94.76 sequence = TCTTTGTATCCGATT... Gene: BT1998: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	* Bacteroides ovatus ATCC 8483 Site: position = -227 score = 86.29 sequence = TCTTTGTATCTGGTT... Gene: BACOVA_01422: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	* Bacteroides fragilis NCTC 9343 Site: position = -216 score = 98.12 sequence = CCTTTGTAGCAGATT... Gene: BF3484: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00513: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Bacteroides eggerthii DSM 20697 Gene: BACEGG_01780: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Bacteroides uniformis ATCC 8492 Gene: BACUNI_01819: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04105: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	* Bacteroides vulgatus ATCC 8482 Site: position = -214 score = 90.73 sequence = CTTTGCAGCTGTCCG... Gene: BVU_1654: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	* Bacteroides dorei DSM 17855 Site: position = -214 score = 90.96 sequence = CTTTGTAGCCGTCCG... Gene: BACDOR_00281: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	* Bacteroides coprophilus DSM 18228 Site: position = -227 score = 88.73 sequence = TTTGTATCGCTTTTC... Gene: BACCOPRO_02553: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	* Bacteroides plebeius DSM 17135 Site: position = -222 score = 81.21 sequence = TTTGTCCTGCTTTTC... Gene: BACPLE_03828: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
nrdG	Bacteroides thetaiotaomicron VPI-5482 Gene: BT1999: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Bacteroides ovatus ATCC 8483 Gene: BACOVA_01423: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Bacteroides fragilis NCTC 9343 Gene: BF3485: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00514: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Bacteroides eggerthii DSM 20697 Gene: BACEGG_01779: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Bacteroides uniformis ATCC 8492 Gene: BACUNI_01818: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04106: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Bacteroides vulgatus ATCC 8482 Gene: BVU_1653: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Bacteroides dorei DSM 17855 Gene: BACDOR_00280: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Bacteroides coprophilus DSM 18228 Gene: BACCOPRO_02554: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Bacteroides plebeius DSM 17135 Gene: BACPLE_03827: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)

CRON 5.
nrdD2	Bacteroides thetaiotaomicron VPI-5482	* Bacteroides ovatus ATCC 8483 Site: position = -350 score = 89.91 sequence = ACTTTGCCGCCAACA... Gene: BACOVA_00801: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	* Bacteroides cellulosilyticus DSM 14838 Site: position = -352 score = 91.97 sequence = ACTTTGTCAGCGATA... Gene: BACCELL_00566: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	* Bacteroides vulgatus ATCC 8482 Site: position = -348 score = 95.27 sequence = ACTTTGTCAGTAATA... Gene: BVU_3105: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	* Bacteroides dorei DSM 17855 Site: position = -350 score = 94.3 sequence = TAACTTTGTCAGTAA... Gene: BACDOR_02872: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
nrdG2	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483 Gene: BACOVA_00802: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_00567: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Bacteroides vulgatus ATCC 8482 Gene: BVU_3106: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Bacteroides dorei DSM 17855 Gene: BACDOR_02871: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)

CRON 6.
nrdA	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	* Bacteroides fragilis NCTC 9343 Site: position = -286 score = 90.85 sequence = ATCTTTGCTCCCTGA... Gene: BF2713: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	2 Bacteroides cellulosilyticus DSM 14838* Gene: BACCELL_04147: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1) Site: position = -279 score = 92.38 sequence = TTATCTTTGTTCCCG... Gene: BACCELL_04148: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	* Bacteroides vulgatus ATCC 8482 Site: position = -276 score = 88.26 sequence = TTATCTTTGTTCCCG... Gene: BVU_3098: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	* Bacteroides dorei DSM 17855 Site: position = -274 score = 88.68 sequence = ATCTTTGTTCCCGAA... Gene: BACDOR_02878: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
nrdB	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343 Gene: BF2714: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Bacteroides stercoris ATCC 43183	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04146: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Bacteroides vulgatus ATCC 8482 Gene: BVU_3097: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Bacteroides dorei DSM 17855 Gene: BACDOR_02879: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)

CRON 7.
btuB5	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343	* Bacteroides stercoris ATCC 43183 Site: position = -340 score = 80.14 sequence = TCTTTACCCCCGGAA... Gene: BACSTE_00632: Outer membrane vitamin B12 receptor BtuB	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	* Bacteroides cellulosilyticus DSM 14838 Site: position = -348 score = 73.23 sequence = TATCTTTGCAATCGG... Gene: BACCELL_04594: Outer membrane vitamin B12 receptor BtuB	* Bacteroides vulgatus ATCC 8482 Site: position = -332 score = 80.08 sequence = CTATCTTTGCAACGG... Gene: BVU_3108: Outer membrane vitamin B12 receptor BtuB	* Bacteroides dorei DSM 17855 Site: position = -330 score = 77.04 sequence = ATCTTTGCAACAGAA... Gene: BACDOR_02869: Outer membrane vitamin B12 receptor BtuB	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Outer membrane vitamin B12 receptor BtuB
cbiK	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	Bacteroides fragilis NCTC 9343	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00633: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Bacteroides eggerthii DSM 20697	Bacteroides uniformis ATCC 8492	Bacteroides cellulosilyticus DSM 14838 Gene: BACCELL_04593: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Bacteroides vulgatus ATCC 8482 Gene: BVU_3107: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Bacteroides dorei DSM 17855 Gene: BACDOR_02870: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)

CRON 8.
metE	Bacteroides thetaiotaomicron VPI-5482	Bacteroides ovatus ATCC 8483	* Bacteroides fragilis NCTC 9343 Site: position = -272 score = 97.72 sequence = TTATATTTGTCGGCA... Gene: BF2696: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	Bacteroides stercoris ATCC 43183 Gene: BACSTE_00512: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	Bacteroides eggerthii DSM 20697 Gene: BACEGG_01781: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	Bacteroides uniformis ATCC 8492 Gene: BACUNI_01820: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	Bacteroides cellulosilyticus DSM 14838	Bacteroides vulgatus ATCC 8482	Bacteroides dorei DSM 17855	Bacteroides coprophilus DSM 18228	Bacteroides plebeius DSM 17135	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

CRON 9.
BT1483	Bacteroides thetaiotaomicron VPI-5482 Gene: BT1483: two-component system sensor histidine kinase	Bacteroides ovatus ATCC 8483 Gene: BACOVA_04216: two-component system sensor histidine kinase	Bacteroides fragilis NCTC 9343 Gene: BF1589: two-component system sensor histidine kinase	* Bacteroides stercoris ATCC 43183 Site: position = 1831 score = 98.76 sequence = ATTATCTTTGCGATG... Gene: BACSTE_01770: two-component system sensor histidine kinase	* Bacteroides eggerthii DSM 20697 Site: position = 1830 score = 102.31 sequence = ATTATCTTTGCAATG... Gene: BACEGG_02061: two-component system sensor histidine kinase	* Bacteroides uniformis ATCC 8492 Site: position = 2122 score = 106.2 sequence = TATCTTTGTCATGCA... Gene: BACUNI_01435: two-component system sensor histidine kinase	* Bacteroides cellulosilyticus DSM 14838 Site: position = 1589 score = 108.01 sequence = TATCTTTGCGATGCA... Gene: BACCELL_05151: two-component system sensor histidine kinase	* Bacteroides vulgatus ATCC 8482 Site: position = 1874 score = 97.65 sequence = TATCTTTGCAGTGCA... Gene: BVU_4096: two-component system sensor histidine kinase	* Bacteroides dorei DSM 17855 Site: position = 1780 score = 97.45 sequence = TGTATCTTTGCGGTG... Gene: BACDOR_00736: two-component system sensor histidine kinase	Bacteroides coprophilus DSM 18228 Gene: BACCOPRO_02951: two-component system sensor histidine kinase	2 Bacteroides plebeius DSM 17135 Gene: BACPLE_03361: two-component system sensor histidine kinase Gene: BACPLE_03361: two-component system sensor histidine kinase	two-component system sensor histidine kinase

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Cobalamin - Bacteroidaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --