Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Bacteroides fragilis NCTC 9343

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Bacteroidaceae
Under regulation:
- Genes 29
- Operons 7
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -302
Score: 74.1
Sequence: ATATTTGCAGCCGCT...
Locus tag: BF2539
Name: btuB4
Funciton: B12-regulated TonB-dependent outer membrane receptor
Locus tag: BF2540
Name: cbiK
Funciton: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
Locus tag: BF2541
Name: btuB
Funciton: Outer membrane vitamin B12 receptor BtuB
Locus tag: BF2542
Name: btuN
Funciton: Optional hypothetical component of the B12 transporter BtuN
Locus tag: BF2543
Name: btuS
Funciton: B12-related chelatase BtuS
Locus tag: BF2544
Name: btuV
Funciton: Predicted component of B12-related transporter
Locus tag: BF2545
Name: btuT
Funciton: Hypothetical transporter BtuT for various metalloporphyrins
Locus tag: BF2546
Name: btuU
Funciton: Predicted component of B12-related transporter
Locus tag: BF2547
Name: cbiHC
Funciton: Cobalt-precorrin-3b C17-methyltransferase / Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: BF2548
Name: cbiET
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: BF2549
Name: cbiGF
Funciton: Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: BF2550
Name: cbiJD
Funciton: Cobalt-precorrin-6x reductase (EC 1.3.1.54) / Cobalt-precorrin-6 synthase, anaerobic
btuB4
B12-regulated TonB-dependent outer membrane receptor
cbiK
Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
btuB
Outer membrane vitamin B12 receptor BtuB
btuN
Optional hypothetical component of the B12 transporter BtuN
btuS
B12-related chelatase BtuS
btuV
Predicted component of B12-related transporter
btuT
Hypothetical transporter BtuT for various metalloporphyrins
btuU
Predicted component of B12-related transporter
cbiHC
Cobalt-precorrin-3b C17-methyltransferase / Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
cbiET
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
cbiGF
Cobalamin biosynthesis protein CbiG / Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
cbiJD
Cobalt-precorrin-6x reductase (EC 1.3.1.54) / Cobalt-precorrin-6 synthase, anaerobic

Position: -286
Score: 90.8
Sequence: ATCTTTGCTCCCTGA...
Locus tag: BF2713
Name: nrdA
Funciton: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
Locus tag: BF2714
Name: nrdB
Funciton: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
nrdA
Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
nrdB
Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)

Position: -216
Score: 98.1
Sequence: CCTTTGTAGCAGATT...
Locus tag: BF3484
Name: nrdD
Funciton: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
Locus tag: BF3485
Name: nrdG
Funciton: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)
nrdD
Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
nrdG
Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)

Position: -356
Score: 86.5
Sequence: ATATTTGTCGCCGAA...
Locus tag: BF3337
Name: pccC
Funciton: Biotin carboxylase of propionyl-CoA carboxylase (EC 6.3.4.14)
Locus tag: BF3338
Name: pccA
Funciton: Biotin carboxyl carrier protein of propionyl-CoA carboxylase
Locus tag: BF3339
Name: pccB
Funciton: Propionyl-CoA carboxylase beta chain (EC 6.4.1.3)
pccC
Biotin carboxylase of propionyl-CoA carboxylase (EC 6.3.4.14)
pccA
Biotin carboxyl carrier protein of propionyl-CoA carboxylase
pccB
Propionyl-CoA carboxylase beta chain (EC 6.4.1.3)

Position: -561
Score: 92.9
Sequence: CTTATCTTTGTCCCG...
Locus tag: BF2538
Name: cbtD
Funciton: Predicted cobalt transporter in Bacteroides_Porphyromonas
Locus tag: BF2537
Name: null
Funciton: Putative membrane protein
Locus tag: BF2536
Name: null
Funciton: Probable integral membrane protein
Locus tag: BF2535
Name: null
Funciton: Hypothetical protein
Locus tag: BF2534
Name: cbiA
Funciton: Cobyrinic acid A,C-diamide synthase
Locus tag: BF2533
Name: pduO
Funciton: Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17)
cbtD
Predicted cobalt transporter in Bacteroides_Porphyromonas
Putative membrane protein
Probable integral membrane protein
Hypothetical protein
cbiA
Cobyrinic acid A,C-diamide synthase
pduO
Cob(I)alamin adenosyltransferase PduO (EC 2.5.1.17)

Position: -272
Score: 97.7
Sequence: TTATATTTGTCGGCA...
Locus tag: BF2696
Name: metE
Funciton: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)

Position: -379
Score: 100.6
Sequence: TTTATCTTTGCAGTG...
Locus tag: BF1583
Name: btuB1
Funciton: Outer membrane vitamin B12 receptor BtuB
Locus tag: BF1582
Name: null
Funciton: Hypothetical protein
Locus tag: BF1581
Name: null
Funciton: Hypothetical protein
btuB1
Outer membrane vitamin B12 receptor BtuB
Hypothetical protein
Hypothetical protein
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