Regulog Cobalamin - Desulfovibrionales

Properties
Regulator type:	RNA regulatory element
Name:	Cobalamin
RFAM:	RF00174
Regulation mode:
Biological process:	Cobalamin biosynthesis
Effector:	Adenosylcobalamin
Phylum:	Proteobacteria/delta

Member of regulog collections

By taxonomy - Desulfovibrionales
By RNA motif - Cobalamin
By effector - Adenosylcobalamin
By pathway - Cobalamin biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Desulfovibrio vulgaris Hildenborough	8	3
Desulfovibrio vulgaris str. Miyazaki F	7	2
Desulfovibrio desulfuricans G20	8	3
Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	6	3
Desulfovibrio piger ATCC 29098	7	3
Desulfovibrio salexigens DSM 2638	10	4
Desulfovibrio magneticus RS-1	7	2
Lawsonia intracellularis PHE/MN1-00
Desulfomicrobium baculatum DSM 4028	12	2
Desulfohalobium retbaense DSM 5692	2	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes											Function

CRON 1.
cbiK	* Desulfovibrio vulgaris Hildenborough Site: position = -318 score = 92.98 sequence = GCCTATGCCGCACGA... Gene: DVU0650: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	* Desulfovibrio vulgaris str. Miyazaki F Site: position = -382 score = 95.02 sequence = CTATCCATGAACCTT... Gene: DvMF_1496: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	* Desulfovibrio desulfuricans G20 Site: position = -103 score = 99.22 sequence = TAACCCGAATCGATT... Gene: Dde_3103: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	Desulfovibrio piger ATCC 29098	* Desulfovibrio salexigens DSM 2638 Site: position = -306 score = 76.17 sequence = ATATTTAGCCTTTGC... Gene: Desal_2307: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	* Desulfovibrio magneticus RS-1 Site: position = -291 score = 83.92 sequence = CTCCCCGGAAATCGA... Gene: DMR_15530: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Lawsonia intracellularis PHE/MN1-00	* Desulfomicrobium baculatum DSM 4028 Site: position = -266 score = 92.2 sequence = GCGTCTTTTCCACTT... Gene: Dbac_1710: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Desulfohalobium retbaense DSM 5692	Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)
btuC	Desulfovibrio vulgaris Hildenborough Gene: DVU0649: Vitamin B12 ABC transporter, permease component BtuC	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_1497: Vitamin B12 ABC transporter, permease component BtuC	Desulfovibrio desulfuricans G20 Gene: Dde_3104: Vitamin B12 ABC transporter, permease component BtuC	* Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 Site: position = -548 score = 77.38 sequence = AAAGTATGCGCGGCA... Gene: Ddes_0796: Vitamin B12 ABC transporter, permease component BtuC	* Desulfovibrio piger ATCC 29098 Site: position = -106 score = 83.07 sequence = TAGAGTAGCGCGTCC... Gene: DESPIG_00414: Vitamin B12 ABC transporter, permease component BtuC	Desulfovibrio salexigens DSM 2638 Gene: Desal_2306: Vitamin B12 ABC transporter, permease component BtuC	Desulfovibrio magneticus RS-1 Gene: DMR_15520: Vitamin B12 ABC transporter, permease component BtuC	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_1711: Vitamin B12 ABC transporter, permease component BtuC	Desulfohalobium retbaense DSM 5692	Vitamin B12 ABC transporter, permease component BtuC
btuD	Desulfovibrio vulgaris Hildenborough Gene: DVU0648: Vitamin B12 ABC transporter, ATPase component BtuD	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_1498: Vitamin B12 ABC transporter, ATPase component BtuD	Desulfovibrio desulfuricans G20 Gene: Dde_3105: Vitamin B12 ABC transporter, ATPase component BtuD	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 Gene: Ddes_0797: Vitamin B12 ABC transporter, ATPase component BtuD	Desulfovibrio piger ATCC 29098 Gene: DESPIG_00415: Vitamin B12 ABC transporter, ATPase component BtuD	Desulfovibrio salexigens DSM 2638 Gene: Desal_2305: Vitamin B12 ABC transporter, ATPase component BtuD	Desulfovibrio magneticus RS-1 Gene: DMR_15510: Vitamin B12 ABC transporter, ATPase component BtuD	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_1712: Vitamin B12 ABC transporter, ATPase component BtuD	Desulfohalobium retbaense DSM 5692	Vitamin B12 ABC transporter, ATPase component BtuD
btuF	Desulfovibrio vulgaris Hildenborough Gene: DVU0647: Vitamin B12 ABC transporter, B12-binding component BtuF	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_1499: Vitamin B12 ABC transporter, B12-binding component BtuF	Desulfovibrio desulfuricans G20 Gene: Dde_3106: Vitamin B12 ABC transporter, B12-binding component BtuF	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 Gene: Ddes_0798: Vitamin B12 ABC transporter, B12-binding component BtuF	Desulfovibrio piger ATCC 29098 Gene: DESPIG_00416: Vitamin B12 ABC transporter, B12-binding component BtuF	Desulfovibrio salexigens DSM 2638 Gene: Desal_2304: Vitamin B12 ABC transporter, B12-binding component BtuF	Desulfovibrio magneticus RS-1 Gene: DMR_15500: Vitamin B12 ABC transporter, B12-binding component BtuF	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_1713: Vitamin B12 ABC transporter, B12-binding component BtuF	Desulfohalobium retbaense DSM 5692 Gene: Dret_0029: Vitamin B12 ABC transporter, B12-binding component BtuF	Vitamin B12 ABC transporter, B12-binding component BtuF
cbiL	Desulfovibrio vulgaris Hildenborough Gene: DVU0646: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_1500: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Desulfovibrio desulfuricans G20 Gene: Dde_3107: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 Gene: Ddes_0799: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Desulfovibrio piger ATCC 29098 Gene: DESPIG_00417: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Desulfovibrio salexigens DSM 2638 Gene: Desal_2303: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Desulfovibrio magneticus RS-1 Gene: DMR_15490: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_1714: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Desulfohalobium retbaense DSM 5692	Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
cbiA	Desulfovibrio vulgaris Hildenborough Gene: DVU3086: Cobyrinic acid A,C-diamide synthase	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_2254: Cobyrinic acid A,C-diamide synthase	Desulfovibrio desulfuricans G20 Gene: Dde_0343: Cobyrinic acid A,C-diamide synthase	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	Desulfovibrio piger ATCC 29098	Desulfovibrio salexigens DSM 2638 Gene: Desal_0269: Cobyrinic acid A,C-diamide synthase	Desulfovibrio magneticus RS-1 Gene: DMR_11850: Cobyrinic acid A,C-diamide synthase	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_1715: Cobyrinic acid A,C-diamide synthase	Desulfohalobium retbaense DSM 5692	Cobyrinic acid A,C-diamide synthase
cbiD	Desulfovibrio vulgaris Hildenborough Gene: DVU2750: Cobalt-precorrin-6 synthase, anaerobic	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_1174: Cobalt-precorrin-6 synthase, anaerobic	Desulfovibrio desulfuricans G20 Gene: Dde_0804: Cobalt-precorrin-6 synthase, anaerobic	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 Gene: Ddes_1978: Cobalt-precorrin-6 synthase, anaerobic	Desulfovibrio piger ATCC 29098 Gene: DESPIG_00350: Cobalt-precorrin-6 synthase, anaerobic	Desulfovibrio salexigens DSM 2638 Gene: Desal_0267: Cobalt-precorrin-6 synthase, anaerobic	Desulfovibrio magneticus RS-1 Gene: DMR_11840: Cobalt-precorrin-6 synthase, anaerobic	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_1716: Cobalt-precorrin-6 synthase, anaerobic	Desulfohalobium retbaense DSM 5692	Cobalt-precorrin-6 synthase, anaerobic
cbiET	Desulfovibrio vulgaris Hildenborough Gene: DVU2749: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_1175: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Desulfovibrio desulfuricans G20 Gene: Dde_0803: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 Gene: Ddes_1979: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Desulfovibrio piger ATCC 29098 Gene: DESPIG_02409: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Desulfovibrio salexigens DSM 2638 Gene: Desal_0265: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Desulfovibrio magneticus RS-1 Gene: DMR_11880: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_1717: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Desulfohalobium retbaense DSM 5692	Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
cbiG	Desulfovibrio vulgaris Hildenborough Gene: DVU3169: Cobalamin biosynthesis protein CbiG	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_2501: Cobalamin biosynthesis protein CbiG	Desulfovibrio desulfuricans G20 Gene: Dde_3181: Cobalamin biosynthesis protein CbiG	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 Gene: Ddes_2015: Cobalamin biosynthesis protein CbiG	Desulfovibrio piger ATCC 29098 Gene: DESPIG_02930: Cobalamin biosynthesis protein CbiG	Desulfovibrio salexigens DSM 2638 Gene: Desal_0754: Cobalamin biosynthesis protein CbiG	Desulfovibrio magneticus RS-1 Gene: DMR_02540: Cobalamin biosynthesis protein CbiG	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_1718: Cobalamin biosynthesis protein CbiG	Desulfohalobium retbaense DSM 5692	Cobalamin biosynthesis protein CbiG
cbiH	Desulfovibrio vulgaris Hildenborough Gene: DVU3170: Cobalt-precorrin-3b C17-methyltransferase	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_2500: Cobalt-precorrin-3b C17-methyltransferase	Desulfovibrio desulfuricans G20	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 Gene: Ddes_2014: Cobalt-precorrin-3b C17-methyltransferase	Desulfovibrio piger ATCC 29098	Desulfovibrio salexigens DSM 2638 Gene: Desal_0755: Cobalt-precorrin-3b C17-methyltransferase	Desulfovibrio magneticus RS-1 Gene: DMR_02550: Cobalt-precorrin-3b C17-methyltransferase	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_1719: Cobalt-precorrin-3b C17-methyltransferase	Desulfohalobium retbaense DSM 5692	Cobalt-precorrin-3b C17-methyltransferase
btuB	Desulfovibrio vulgaris Hildenborough	Desulfovibrio vulgaris str. Miyazaki F	Desulfovibrio desulfuricans G20	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	Desulfovibrio piger ATCC 29098	Desulfovibrio salexigens DSM 2638	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028	* Desulfohalobium retbaense DSM 5692 Site: position = -302 score = 108.92 sequence = GTTGTATCCTGCCCC... Gene: Dret_0028: Outer membrane vitamin B12 receptor BtuB	Outer membrane vitamin B12 receptor BtuB

CRON 2.
nrdD	Desulfovibrio vulgaris Hildenborough Gene: DVU0299: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_1819: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Desulfovibrio desulfuricans G20 Gene: Dde_0277: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	* Desulfovibrio piger ATCC 29098 Site: position = -330 score = 71.63 sequence = CATCTTGAGCGGGCA... Gene: DESPIG_00246: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Desulfovibrio salexigens DSM 2638 Gene: Desal_2955: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	2 Desulfovibrio magneticus RS-1* Gene: DMR_44720: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2) Site: position = -388 score = 79.47 sequence = AAGAGGGAATCCGGT... Gene: DMR_44320: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028 Gene: Dbac_3397: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Desulfohalobium retbaense DSM 5692 Gene: Dret_0068: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
DESPIG_00247	Desulfovibrio vulgaris Hildenborough	Desulfovibrio vulgaris str. Miyazaki F	Desulfovibrio desulfuricans G20	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	Desulfovibrio piger ATCC 29098 Gene: DESPIG_00247: Hypothetical protein	Desulfovibrio salexigens DSM 2638	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028	Desulfohalobium retbaense DSM 5692	Hypothetical protein
nrdG	Desulfovibrio vulgaris Hildenborough Gene: DVU0300: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_1818: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Desulfovibrio desulfuricans G20 Gene: Dde_0278: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 Gene: Ddes_1073: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Desulfovibrio piger ATCC 29098 Gene: DESPIG_00248: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Desulfovibrio salexigens DSM 2638 Gene: Desal_2954: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	2 Desulfovibrio magneticus RS-1 Gene: DMR_44710: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4) Gene: DMR_44330: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Lawsonia intracellularis PHE/MN1-00	* Desulfomicrobium baculatum DSM 4028 Site: position = -236 score = 55.65 sequence = GTCCTAATACTTAAC... Gene: Dbac_3396: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Desulfohalobium retbaense DSM 5692 Gene: Dret_0069: Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)	Ribonucleotide reductase of class III (anaerobic), activating protein (EC 1.97.1.4)

CRON 3.
nrdD	* Desulfovibrio vulgaris Hildenborough Site: position = -348 score = 56.34 sequence = TTCCCCGTCTGCTAT... Gene: DVU2947: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	* Desulfovibrio vulgaris str. Miyazaki F Site: position = -372 score = 26.93 sequence = CAAAGGGAATCCGGT... Gene: DvMF_1473: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	* Desulfovibrio desulfuricans G20 Site: position = -265 score = 15.74 sequence = AACCGGTGTAATTCC... Gene: Dde_3016: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	Desulfovibrio piger ATCC 29098	* Desulfovibrio salexigens DSM 2638 Site: position = -420 score = 40.74 sequence = ACTTCAGGAATCCGT... Gene: Desal_3514: Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028	Desulfohalobium retbaense DSM 5692	Ribonucleotide reductase of class III (anaerobic), large subunit (EC 1.17.4.2)
DVU2946	Desulfovibrio vulgaris Hildenborough Gene: DVU2946: Hypothetical protein	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_1472: Hypothetical protein	Desulfovibrio desulfuricans G20 Gene: Dde_3015: Hypothetical protein	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	Desulfovibrio piger ATCC 29098	Desulfovibrio salexigens DSM 2638 Gene: Desal_3513: Hypothetical protein	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028	Desulfohalobium retbaense DSM 5692	Hypothetical protein

CRON 4.
metE	* Desulfovibrio vulgaris Hildenborough Site: position = -322 score = 58.99 sequence = TATCAATATGGAGTG... Gene: DVU3371: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_2035: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	* Desulfovibrio desulfuricans G20 Site: position = -297 score = 79.25 sequence = TTGAATATTGATGAA... Gene: Dde_2328: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	Desulfovibrio piger ATCC 29098	* Desulfovibrio salexigens DSM 2638 Site: position = -265 score = 58.56 sequence = TATATTGAATTTGAT... Gene: Desal_0813: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028	Desulfohalobium retbaense DSM 5692	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
metF	Desulfovibrio vulgaris Hildenborough Gene: DVU0997: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	Desulfovibrio vulgaris str. Miyazaki F Gene: DvMF_3034: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	Desulfovibrio desulfuricans G20 Gene: Dde_2525: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 Gene: Ddes_2008: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	Desulfovibrio piger ATCC 29098 Gene: DESPIG_02490: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	Desulfovibrio salexigens DSM 2638 Gene: Desal_0814: 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028	Desulfohalobium retbaense DSM 5692	5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20)

CRON 5.
cbiK2	Desulfovibrio vulgaris Hildenborough	Desulfovibrio vulgaris str. Miyazaki F	Desulfovibrio desulfuricans G20	* Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 Site: position = -255 score = 55.61 sequence = TGACATTTACCGCGC... Gene: Ddes_2334: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	* Desulfovibrio piger ATCC 29098 Site: position = -220 score = 47.83 sequence = CCCAAACCGTTTCTG... Gene: DESPIG_01756: Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)	Desulfovibrio salexigens DSM 2638	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028	Desulfohalobium retbaense DSM 5692	Sirohydrochlorin cobaltochelatase CbiK (EC 4.99.1.3)

CRON 6.
Ddes_1071	Desulfovibrio vulgaris Hildenborough	Desulfovibrio vulgaris str. Miyazaki F	Desulfovibrio desulfuricans G20	* Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 Site: position = -138 score = 102.72 sequence = ATTTTCTAGACATTG... Gene: Ddes_1071: Hypothetical protein	Desulfovibrio piger ATCC 29098	Desulfovibrio salexigens DSM 2638	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028	Desulfohalobium retbaense DSM 5692	Hypothetical protein

CRON 7.
nrdA	Desulfovibrio vulgaris Hildenborough	Desulfovibrio vulgaris str. Miyazaki F	Desulfovibrio desulfuricans G20	Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774	Desulfovibrio piger ATCC 29098	* Desulfovibrio salexigens DSM 2638 Site: position = -393 score = 38.6 sequence = TCGTTGTGTTTTCAC... Gene: Desal_0826: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)	Desulfovibrio magneticus RS-1	Lawsonia intracellularis PHE/MN1-00	Desulfomicrobium baculatum DSM 4028	Desulfohalobium retbaense DSM 5692	Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Cobalamin - Desulfovibrionales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --