Propagated regulons of Lactobacillus salivarius subsp. salivarius UCC118
| Type | Regulator | Effector | Pathway | Genes | Sites |
|---|---|---|---|---|---|
| TF | ArgR | Arginine | Arginine degradation; Arginine biosynthesis | 5 | 67 |
| TF | BirA | Biotin | Biotin biosynthesis | 1 | 1 |
| TF | CcpA | HPr, phosphocarrier protein; Fructose-1,6-bisphosphate | Carbon catabolism | 34 | 53 |
| TF | CggR | Fructose-1,6-bisphosphate | Glycolysis | 1 | 1 |
| TF | CopR | Copper ion, (Cu2+) | Copper homeostasis | 1 | 1 |
| TF | CtsR | Heat shock | Heat shock response | 1 | 1 |
| TF | FabT | Long-chain acyl-ACP | Fatty acid biosynthesis | 1 | 1 |
| TF | FlpA | Oxygen | Heavy metal resistance | 4 | 4 |
| TF | FruR | Fructose-6-phosphate | Fructose utilization | 1 | 6 |
| TF | GalR | Galactose | Galactosides utilization; Galactose utilization | 3 | 8 |
| TF | GlnR | Phosphorylated NtrB, signal histidine kinase | Nitrogen assimilation | 5 | 7 |
| TF | GutR | HPr, phosphocarrier protein; GutB, sorbitol-specific PTS EIIB component | Sorbitol utilization | 1 | 1 |
| TF | HrcA | Heat shock | Heat shock response | 2 | 3 |
| TF | LBA0573 | Multidrug resistance | 1 | 1 | |
| TF | LexA | DNA damage | SOS response | 5 | 5 |
| TF | Lp_2742 | Multidrug efflux; Multidrug resistance | 1 | 1 | |
| TF | MalR | Maltose | Maltose utilization; Maltodextrin utilization | 1 | 1 |
| TF | MleR | L-malate | Malate utilization | 2 | 2 |
| TF | MntR | Manganese ion, (Mn2+) | Manganese homeostasis | 1 | 1 |
| TF | MtlR | HPr, phosphocarrier protein; MtlA, mannitol-specific enzyme IICB PTS component | Mannitol utilization | 1 | 1 |
| TF | NagR | N-acetylglucosamine-6-phosphate | N-acetylglucosamine utilization | 3 | 5 |
| TF | NrdR | Deoxyribonucleotides | Deoxyribonucleotide biosynthesis | 2 | 6 |
| TF | NigR | Nigerose-6-phosphate | Nigerose utilization | 1 | 1 |
| TF | PerR | Iron ion, (Fe2+); Manganese ion, (Mn2+); Hydrogen peroxide | Manganese homeostasis; Oxidative stress response; Iron homeostasis | 4 | 4 |
| TF | PurR | 5-phosphoribosyl 1-pyrophosphate | Purine metabolism | 11 | 17 |
| TF | RpiR | Sugar utilization | 2 | 2 | |
| TF | Rex | NADH | Energy metabolism | 3 | 3 |
| TF | ScrR | Sucrose-6-phosphate | Sucrose utilization | 2 | 4 |
| TF | TreR | Trehalose-6-phosphate | Trehalose utilization | 2 | 2 |
| TF | YwzG | Transport | 1 | 1 | |
| TF | YxeR | Antibiotic resistance | 2 | 3 | |
| TF | Zur | Zinc ion, (Zn2+) | Zinc homeostasis | 3 | 4 |