Propagation of PurR regulog to Lactobacillus salivarius subsp. salivarius UCC118
| Source regulog: | PurR - Lactobacillaceae |
| Regulator type: | Transcription factor |
| Regulator family: | PurR |
| Regulation mode: | repressor |
| Biological process: | Purine metabolism |
| Effector: | 5-phosphoribosyl 1-pyrophosphate |
| Phylum: | Firmicutes |
| Propagated regulon: | |
| Target genome | Lactobacillus salivarius subsp. salivarius UCC118 |
| Orthologous TF(s) | LSL_0315 |
| Regulated genes | 11 |
| Locus tag | Position | Score | Sequence | |
|---|---|---|---|---|
|
Position: -280
Score: 4.3 Sequence: AAAAAAGAACAAA
Position: -116
Score: 5.4 Sequence: AAAAACGAACTTT
Locus tag: LSL_0315
|
||||
| LSL_0315 | -280 | 4.3 | AAAAAAGAACAAA | |
| -116 | 5.4 | AAAAACGAACTTT | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: purR | ||||
| Ortholog function: Purine metabolism transcriptional regulator PurR, PurR family | ||||
| Lactobacillus acidophilus NCFM | LBA0218 | -27 | 4.8 | AAAACCAAACATT |
| Lactobacillus brevis ATCC 367 | LVIS_0474 | -91 | 5.3 | AAACCCGAACAAT |
| Lactobacillus casei ATCC 334 | LSEI_2587 | -126 | 4.8 | AAATGCGAACGTT |
| Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 | LBUL_0302 | -54 | 4.3 | AAAAACAGACATT |
| Lactobacillus fermentum IFO 3956 | LAF_0194 | -98 | 5.2 | AAAGACGAACAAT |
| Lactobacillus helveticus DPC 4571 | lhv_0234 | -27 | 4.1 | AAAGCCAAACGTT |
| Lactobacillus johnsonii NCC 533 | LJ0207 | -105 | 4.1 | TATTACGAACAAT |
| Lactobacillus plantarum WCFS1 | lp_0466 | 12 | 4.3 | AGAAGCGAACGTT |
| Lactobacillus reuteri JCM 1112 | LAR_0210 | -64 | 5.2 | AAATCCGAACATT |
| Lactobacillus rhamnosus GG | LGG_02564 | -126 | 4.8 | AAATGCGAACGTT |
| Lactobacillus sakei subsp. sakei 23K | LSA1651 | -120 | 5.6 | AAAAACGAACAAT |
| Lactobacillus salivarius subsp. salivarius UCC118 | LSL_0315 | -116 | 5.4 | AAAAACGAACTTT |
| Pediococcus pentosaceus ATCC 25745 | PEPE_0292 | -103 | 5.2 | AAATCCGAACATT |
|
Position: -68
Score: 4.1 Sequence: AAATTCGAATTTT
Locus tag: LSL_0515
|
||||
| LSL_0515 | -68 | 4.1 | AAATTCGAATTTT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: purE | ||||
| Ortholog function: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21) | ||||
| Lactobacillus acidophilus NCFM | LBA1561 | -59 | 4.4 | ATATAAGAACAAT |
| Lactobacillus casei ATCC 334 | LSEI_1756 | -107 | 5.3 | AAACACGAACGAT |
| Lactobacillus fermentum IFO 3956 | LAF_0118 | -106 | 5.2 | AAATCCGAACAAT |
| Lactobacillus helveticus DPC 4571 | lhv_1534 | -73 | 4.1 | AAATACAAACAAA |
| Lactobacillus plantarum WCFS1 | lp_2729 | -104 | 5 | TAACACGAACATT |
| Lactobacillus reuteri JCM 1112 | LAR_0128 | -102 | 4.9 | ATACACGAACTAT |
| Lactobacillus rhamnosus GG | LGG_01814 | -108 | 5.5 | AAATACGAACATT |
| -96 | 4.3 | TAAAACGAATAAT | ||
| Lactobacillus sakei subsp. sakei 23K | LSA0652 | -112 | 4.3 | TAACACGTACAAT |
| Lactobacillus salivarius subsp. salivarius UCC118 | LSL_0515 | -68 | 4.1 | AAATTCGAATTTT |
| Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 | LEUM_0718 | -137 | 4.1 | ATATACGAACTCT |
| Oenococcus oeni PSU-1 | OEOE_1138 | -130 | 4.6 | AAACACGAAATAT |
| -79 | 5.3 | AAAAACGAACGTT | ||
| Pediococcus pentosaceus ATCC 25745 | PEPE_1467 | -123 | 5.4 | AAAAACGAACTTT |
|
Position: -229
Score: 3.9 Sequence: AAAAACGTATTAT
Position: -27
Score: 5.2 Sequence: AAAGACGAACAAT
Locus tag: LSL_0663
|
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| LSL_0663 | -229 | 3.9 | AAAAACGTATTAT | |
| -27 | 5.2 | AAAGACGAACAAT | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: purC | ||||
| Ortholog function: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6) | ||||
| Lactobacillus acidophilus NCFM | LBA1559 | -151 | 5.3 | AAACACGAACGAT |
| Lactobacillus casei ATCC 334 | LSEI_1754 | -107 | 5.3 | AAACACGAACGAT |
| Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 | LBUL_1338 | -60 | 3.4 | AATTACGAATAGT |
| Lactobacillus fermentum IFO 3956 | LAF_0124 | -155 | 5.6 | AAACACGAACATT |
| Lactobacillus plantarum WCFS1 | lp_2727 | -104 | 5 | TAACACGAACATT |
| Lactobacillus reuteri JCM 1112 | LAR_0131 | -153 | 5.6 | AAACACGAACAAT |
| Lactobacillus rhamnosus GG | LGG_01812 | -108 | 5.5 | AAATACGAACATT |
| -96 | 4.3 | TAAAACGAATAAT | ||
| Lactobacillus sakei subsp. sakei 23K | LSA0655 | -110 | 4.9 | ATAAACGAACTTT |
| -58 | 5.6 | AAAAACGAACAAT | ||
| Lactobacillus salivarius subsp. salivarius UCC118 | LSL_0663 | -27 | 5.2 | AAAGACGAACAAT |
| Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 | LEUM_0720 | -137 | 4.1 | ATATACGAACTCT |
| Oenococcus oeni PSU-1 | OEOE_1136 | -130 | 4.6 | AAACACGAAATAT |
| -79 | 5.3 | AAAAACGAACGTT | ||
| Pediococcus pentosaceus ATCC 25745 | PEPE_1465 | -123 | 5.4 | AAAAACGAACTTT |
|
Position: 15
Score: 3.3 Sequence: ACACCTGAACAAA
Position: 27
Score: 3.8 Sequence: ATAAAAGAACAAA
Locus tag: LSL_0666
|
||||
| LSL_0666 | 15 | 3.3 | ACACCTGAACAAA | |
| 27 | 3.8 | ATAAAAGAACAAA | ||
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: purL | ||||
| Ortholog function: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) | ||||
| Lactobacillus acidophilus NCFM | LBA1556 | -151 | 5.3 | AAACACGAACGAT |
| Lactobacillus casei ATCC 334 | LSEI_1751 | -107 | 5.3 | AAACACGAACGAT |
| Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 | LBUL_1335 | -60 | 3.4 | AATTACGAATAGT |
| Lactobacillus fermentum IFO 3956 | LAF_0127 | -155 | 5.6 | AAACACGAACATT |
| Lactobacillus plantarum WCFS1 | lp_2724 | -104 | 5 | TAACACGAACATT |
| Lactobacillus reuteri JCM 1112 | LAR_0134 | -153 | 5.6 | AAACACGAACAAT |
| Lactobacillus rhamnosus GG | LGG_01809 | -108 | 5.5 | AAATACGAACATT |
| -96 | 4.3 | TAAAACGAATAAT | ||
| Lactobacillus sakei subsp. sakei 23K | LSA0658 | -110 | 4.9 | ATAAACGAACTTT |
| -58 | 5.6 | AAAAACGAACAAT | ||
| Lactobacillus salivarius subsp. salivarius UCC118 | LSL_0666 | -27 | 5.2 | AAAGACGAACAAT |
| Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 | LEUM_0723 | -137 | 4.1 | ATATACGAACTCT |
| Oenococcus oeni PSU-1 | OEOE_1133 | -130 | 4.6 | AAACACGAAATAT |
| -79 | 5.3 | AAAAACGAACGTT | ||
| Pediococcus pentosaceus ATCC 25745 | PEPE_1462 | -123 | 5.4 | AAAAACGAACTTT |
|
Position: 1
Score: 3.6 Sequence: TGAAACGAGCATT
Locus tag: LSL_0670
|
||||
| LSL_0670 | 1 | 3.6 | TGAAACGAGCATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: purH | ||||
| Ortholog function: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) | ||||
| Lactobacillus acidophilus NCFM | LBA1552 | -151 | 5.3 | AAACACGAACGAT |
| Lactobacillus casei ATCC 334 | LSEI_1747 | -107 | 5.3 | AAACACGAACGAT |
| Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 | LBUL_1331 | -60 | 3.4 | AATTACGAATAGT |
| Lactobacillus fermentum IFO 3956 | LAF_0131 | -155 | 5.6 | AAACACGAACATT |
| Lactobacillus plantarum WCFS1 | lp_2720 | -104 | 5 | TAACACGAACATT |
| Lactobacillus reuteri JCM 1112 | LAR_0138 | -153 | 5.6 | AAACACGAACAAT |
| Lactobacillus rhamnosus GG | LGG_01805 | -108 | 5.5 | AAATACGAACATT |
| -96 | 4.3 | TAAAACGAATAAT | ||
| Lactobacillus sakei subsp. sakei 23K | LSA0662 | -110 | 4.9 | ATAAACGAACTTT |
| -58 | 5.6 | AAAAACGAACAAT | ||
| Lactobacillus salivarius subsp. salivarius UCC118 | LSL_0670 | -27 | 5.2 | AAAGACGAACAAT |
| Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 | LEUM_0727 | -137 | 4.1 | ATATACGAACTCT |
| Pediococcus pentosaceus ATCC 25745 | PEPE_1458 | -123 | 5.4 | AAAAACGAACTTT |
|
Position: 6
Score: 3.4 Sequence: GAAAACGTAAATT
Locus tag: LSL_0671
|
||||
| LSL_0671 | 6 | 3.4 | GAAAACGTAAATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: purD | ||||
| Ortholog function: Phosphoribosylamine--glycine ligase (EC 6.3.4.13) | ||||
| Lactobacillus acidophilus NCFM | LBA1551 | -151 | 5.3 | AAACACGAACGAT |
| Lactobacillus casei ATCC 334 | LSEI_1746 | -107 | 5.3 | AAACACGAACGAT |
| Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 | LBUL_1330 | -60 | 3.4 | AATTACGAATAGT |
| Lactobacillus plantarum WCFS1 | lp_2719 | -104 | 5 | TAACACGAACATT |
| Lactobacillus reuteri JCM 1112 | LAR_0139 | -153 | 5.6 | AAACACGAACAAT |
| Lactobacillus rhamnosus GG | LGG_01803 | -108 | 5.5 | AAATACGAACATT |
| -96 | 4.3 | TAAAACGAATAAT | ||
| Lactobacillus sakei subsp. sakei 23K | LSA0663 | -110 | 4.9 | ATAAACGAACTTT |
| -58 | 5.6 | AAAAACGAACAAT | ||
| Lactobacillus salivarius subsp. salivarius UCC118 | LSL_0671 | -27 | 5.2 | AAAGACGAACAAT |
| Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293 | LEUM_0700 | -106 | 5.3 | AAAAACGAACTAT |
| Pediococcus pentosaceus ATCC 25745 | PEPE_1457 | -123 | 5.4 | AAAAACGAACTTT |
|
Position: -130
Score: 5.6 Sequence: AAACACGAACATT
Locus tag: LSL_1139
|
||||
| LSL_1139 | -130 | 5.6 | AAACACGAACATT | |
| Supported by regulated orthologs from reference regulons | ||||
| Ortholog gene name: guaC | ||||
| Ortholog function: GMP reductase (EC 1.7.1.7) | ||||
| Lactobacillus acidophilus NCFM | LBA1893 | -120 | 4.4 | AAAACCGAATTAT |
| Lactobacillus brevis ATCC 367 | LVIS_0226 | -247 | 5.3 | AAAAGCGAACATT |
| Lactobacillus casei ATCC 334 | LSEI_0911 | -135 | 5.6 | AAACACGAACATT |
| Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365 | LBUL_0246 | -111 | 4.5 | AAATCCGAATAAT |
| -4 | 5 | AAAAATGAACAAT | ||
| Lactobacillus johnsonii NCC 533 | LJ0441 | -160 | 4.1 | AAAACCGAAGACT |
| Lactobacillus plantarum WCFS1 | lp_3271 | -280 | 5.6 | AAACACGAACATT |
| -239 | 4.5 | AGAGACGAACAAT | ||
| -135 | 5.1 | AAACAAGAACATT | ||
| Lactobacillus rhamnosus GG | LGG_00874 | -134 | 5.6 | AAACACGAACATT |
| Lactobacillus salivarius subsp. salivarius UCC118 | LSL_1139 | -130 | 5.6 | AAACACGAACATT |
| Oenococcus oeni PSU-1 | OEOE_0535 | -176 | 4.1 | AAAAACTAACAAG |
| Pediococcus pentosaceus ATCC 25745 | PEPE_0595 | -99 | 4.6 | GAAAACGAACTTT |