Propagation of PurR regulog to Lactobacillus salivarius subsp. salivarius UCC118

Reference regulog properties
Source regulog:	PurR - Lactobacillaceae
Regulator type:	Transcription factor
Regulator family:	PurR
Regulation mode:	repressor
Biological process:	Purine metabolism
Effector:	5-phosphoribosyl 1-pyrophosphate
Phylum:	Firmicutes
Propagated regulon:
Target genome	Lactobacillus salivarius subsp. salivarius UCC118
Orthologous TF(s)	LSL_0315
Regulated genes	11

Built upon 76 sites [see more]

Predicted regulatory interactions in *Lactobacillus salivarius subsp. salivarius UCC118*
	Locus tag	Position	Score	Sequence
Position: -280 Score: 4.3 Sequence: AAAAAAGAACAAA Position: -116 Score: 5.4 Sequence: AAAAACGAACTTT Locus tag: LSL_0315
	LSL_0315	-280	4.3	AAAAAAGAACAAA
		-116	5.4	AAAAACGAACTTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purR
Ortholog function: Purine metabolism transcriptional regulator PurR, PurR family
Lactobacillus acidophilus NCFM	LBA0218	-27	4.8	AAAACCAAACATT
Lactobacillus brevis ATCC 367	LVIS_0474	-91	5.3	AAACCCGAACAAT
Lactobacillus casei ATCC 334	LSEI_2587	-126	4.8	AAATGCGAACGTT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	LBUL_0302	-54	4.3	AAAAACAGACATT
Lactobacillus fermentum IFO 3956	LAF_0194	-98	5.2	AAAGACGAACAAT
Lactobacillus helveticus DPC 4571	lhv_0234	-27	4.1	AAAGCCAAACGTT
Lactobacillus johnsonii NCC 533	LJ0207	-105	4.1	TATTACGAACAAT
Lactobacillus plantarum WCFS1	lp_0466	12	4.3	AGAAGCGAACGTT
Lactobacillus reuteri JCM 1112	LAR_0210	-64	5.2	AAATCCGAACATT
Lactobacillus rhamnosus GG	LGG_02564	-126	4.8	AAATGCGAACGTT
Lactobacillus sakei subsp. sakei 23K	LSA1651	-120	5.6	AAAAACGAACAAT
Lactobacillus salivarius subsp. salivarius UCC118	LSL_0315	-116	5.4	AAAAACGAACTTT
Pediococcus pentosaceus ATCC 25745	PEPE_0292	-103	5.2	AAATCCGAACATT

Position: -68 Score: 4.1 Sequence: AAATTCGAATTTT Locus tag: LSL_0515
	LSL_0515	-68	4.1	AAATTCGAATTTT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purE
Ortholog function: Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)
Lactobacillus acidophilus NCFM	LBA1561	-59	4.4	ATATAAGAACAAT
Lactobacillus casei ATCC 334	LSEI_1756	-107	5.3	AAACACGAACGAT
Lactobacillus fermentum IFO 3956	LAF_0118	-106	5.2	AAATCCGAACAAT
Lactobacillus helveticus DPC 4571	lhv_1534	-73	4.1	AAATACAAACAAA
Lactobacillus plantarum WCFS1	lp_2729	-104	5	TAACACGAACATT
Lactobacillus reuteri JCM 1112	LAR_0128	-102	4.9	ATACACGAACTAT
Lactobacillus rhamnosus GG	LGG_01814	-108	5.5	AAATACGAACATT
		-96	4.3	TAAAACGAATAAT
Lactobacillus sakei subsp. sakei 23K	LSA0652	-112	4.3	TAACACGTACAAT
Lactobacillus salivarius subsp. salivarius UCC118	LSL_0515	-68	4.1	AAATTCGAATTTT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	LEUM_0718	-137	4.1	ATATACGAACTCT
Oenococcus oeni PSU-1	OEOE_1138	-130	4.6	AAACACGAAATAT
		-79	5.3	AAAAACGAACGTT
Pediococcus pentosaceus ATCC 25745	PEPE_1467	-123	5.4	AAAAACGAACTTT

Position: -229 Score: 3.9 Sequence: AAAAACGTATTAT Position: -27 Score: 5.2 Sequence: AAAGACGAACAAT Locus tag: LSL_0663
	LSL_0663	-229	3.9	AAAAACGTATTAT
		-27	5.2	AAAGACGAACAAT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purC
Ortholog function: Phosphoribosylaminoimidazole-succinocarboxamide synthase (EC 6.3.2.6)
Lactobacillus acidophilus NCFM	LBA1559	-151	5.3	AAACACGAACGAT
Lactobacillus casei ATCC 334	LSEI_1754	-107	5.3	AAACACGAACGAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	LBUL_1338	-60	3.4	AATTACGAATAGT
Lactobacillus fermentum IFO 3956	LAF_0124	-155	5.6	AAACACGAACATT
Lactobacillus plantarum WCFS1	lp_2727	-104	5	TAACACGAACATT
Lactobacillus reuteri JCM 1112	LAR_0131	-153	5.6	AAACACGAACAAT
Lactobacillus rhamnosus GG	LGG_01812	-108	5.5	AAATACGAACATT
		-96	4.3	TAAAACGAATAAT
Lactobacillus sakei subsp. sakei 23K	LSA0655	-110	4.9	ATAAACGAACTTT
		-58	5.6	AAAAACGAACAAT
Lactobacillus salivarius subsp. salivarius UCC118	LSL_0663	-27	5.2	AAAGACGAACAAT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	LEUM_0720	-137	4.1	ATATACGAACTCT
Oenococcus oeni PSU-1	OEOE_1136	-130	4.6	AAACACGAAATAT
		-79	5.3	AAAAACGAACGTT
Pediococcus pentosaceus ATCC 25745	PEPE_1465	-123	5.4	AAAAACGAACTTT

Position: 15 Score: 3.3 Sequence: ACACCTGAACAAA Position: 27 Score: 3.8 Sequence: ATAAAAGAACAAA Locus tag: LSL_0666
	LSL_0666	15	3.3	ACACCTGAACAAA
		27	3.8	ATAAAAGAACAAA
Supported by regulated orthologs from reference regulons
Ortholog gene name: purL
Ortholog function: Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)
Lactobacillus acidophilus NCFM	LBA1556	-151	5.3	AAACACGAACGAT
Lactobacillus casei ATCC 334	LSEI_1751	-107	5.3	AAACACGAACGAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	LBUL_1335	-60	3.4	AATTACGAATAGT
Lactobacillus fermentum IFO 3956	LAF_0127	-155	5.6	AAACACGAACATT
Lactobacillus plantarum WCFS1	lp_2724	-104	5	TAACACGAACATT
Lactobacillus reuteri JCM 1112	LAR_0134	-153	5.6	AAACACGAACAAT
Lactobacillus rhamnosus GG	LGG_01809	-108	5.5	AAATACGAACATT
		-96	4.3	TAAAACGAATAAT
Lactobacillus sakei subsp. sakei 23K	LSA0658	-110	4.9	ATAAACGAACTTT
		-58	5.6	AAAAACGAACAAT
Lactobacillus salivarius subsp. salivarius UCC118	LSL_0666	-27	5.2	AAAGACGAACAAT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	LEUM_0723	-137	4.1	ATATACGAACTCT
Oenococcus oeni PSU-1	OEOE_1133	-130	4.6	AAACACGAAATAT
		-79	5.3	AAAAACGAACGTT
Pediococcus pentosaceus ATCC 25745	PEPE_1462	-123	5.4	AAAAACGAACTTT

Position: 1 Score: 3.6 Sequence: TGAAACGAGCATT Locus tag: LSL_0670
	LSL_0670	1	3.6	TGAAACGAGCATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purH
Ortholog function: IMP cyclohydrolase (EC 3.5.4.10) / Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
Lactobacillus acidophilus NCFM	LBA1552	-151	5.3	AAACACGAACGAT
Lactobacillus casei ATCC 334	LSEI_1747	-107	5.3	AAACACGAACGAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	LBUL_1331	-60	3.4	AATTACGAATAGT
Lactobacillus fermentum IFO 3956	LAF_0131	-155	5.6	AAACACGAACATT
Lactobacillus plantarum WCFS1	lp_2720	-104	5	TAACACGAACATT
Lactobacillus reuteri JCM 1112	LAR_0138	-153	5.6	AAACACGAACAAT
Lactobacillus rhamnosus GG	LGG_01805	-108	5.5	AAATACGAACATT
		-96	4.3	TAAAACGAATAAT
Lactobacillus sakei subsp. sakei 23K	LSA0662	-110	4.9	ATAAACGAACTTT
		-58	5.6	AAAAACGAACAAT
Lactobacillus salivarius subsp. salivarius UCC118	LSL_0670	-27	5.2	AAAGACGAACAAT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	LEUM_0727	-137	4.1	ATATACGAACTCT
Pediococcus pentosaceus ATCC 25745	PEPE_1458	-123	5.4	AAAAACGAACTTT

Position: 6 Score: 3.4 Sequence: GAAAACGTAAATT Locus tag: LSL_0671
	LSL_0671	6	3.4	GAAAACGTAAATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: purD
Ortholog function: Phosphoribosylamine--glycine ligase (EC 6.3.4.13)
Lactobacillus acidophilus NCFM	LBA1551	-151	5.3	AAACACGAACGAT
Lactobacillus casei ATCC 334	LSEI_1746	-107	5.3	AAACACGAACGAT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	LBUL_1330	-60	3.4	AATTACGAATAGT
Lactobacillus plantarum WCFS1	lp_2719	-104	5	TAACACGAACATT
Lactobacillus reuteri JCM 1112	LAR_0139	-153	5.6	AAACACGAACAAT
Lactobacillus rhamnosus GG	LGG_01803	-108	5.5	AAATACGAACATT
		-96	4.3	TAAAACGAATAAT
Lactobacillus sakei subsp. sakei 23K	LSA0663	-110	4.9	ATAAACGAACTTT
		-58	5.6	AAAAACGAACAAT
Lactobacillus salivarius subsp. salivarius UCC118	LSL_0671	-27	5.2	AAAGACGAACAAT
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293	LEUM_0700	-106	5.3	AAAAACGAACTAT
Pediococcus pentosaceus ATCC 25745	PEPE_1457	-123	5.4	AAAAACGAACTTT

Position: -130 Score: 5.6 Sequence: AAACACGAACATT Locus tag: LSL_1139
	LSL_1139	-130	5.6	AAACACGAACATT
Supported by regulated orthologs from reference regulons
Ortholog gene name: guaC
Ortholog function: GMP reductase (EC 1.7.1.7)
Lactobacillus acidophilus NCFM	LBA1893	-120	4.4	AAAACCGAATTAT
Lactobacillus brevis ATCC 367	LVIS_0226	-247	5.3	AAAAGCGAACATT
Lactobacillus casei ATCC 334	LSEI_0911	-135	5.6	AAACACGAACATT
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365	LBUL_0246	-111	4.5	AAATCCGAATAAT
		-4	5	AAAAATGAACAAT
Lactobacillus johnsonii NCC 533	LJ0441	-160	4.1	AAAACCGAAGACT
Lactobacillus plantarum WCFS1	lp_3271	-280	5.6	AAACACGAACATT
		-239	4.5	AGAGACGAACAAT
		-135	5.1	AAACAAGAACATT
Lactobacillus rhamnosus GG	LGG_00874	-134	5.6	AAACACGAACATT
Lactobacillus salivarius subsp. salivarius UCC118	LSL_1139	-130	5.6	AAACACGAACATT
Oenococcus oeni PSU-1	OEOE_0535	-176	4.1	AAAAACTAACAAG
Pediococcus pentosaceus ATCC 25745	PEPE_0595	-99	4.6	GAAAACGAACTTT

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Propagation of PurR regulog to Lactobacillus salivarius subsp. salivarius UCC118

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --