Regulog Zur - Staphylococcaceae

Properties
Regulator type:	Transcription factor
Regulator family:	FUR
Regulation mode:	repressor
Biological process:	Zinc homeostasis
Effector:	Zinc ion, (Zn2+)
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 56 sites [see more]

Member of regulog collections

By taxonomy - Staphylococcaceae
By trascription factor - Zur
By TF family - FUR
By effector - Zinc ion, (Zn2+)
By pathway - Zinc homeostasis

Statistics of regulated genes
Genome	Genes	Operons
Staphylococcus aureus subsp. aureus N315	12	8
Staphylococcus capitis SK14	11	9
Staphylococcus epidermidis ATCC 12228	11	7
Staphylococcus carnosus subsp. carnosus TM300	12	8
Staphylococcus haemolyticus JCSC1435	12	10
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	9	7
Macrococcus caseolyticus JCSC5402	2	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes								Function

CRON 1.
znuC	* Staphylococcus aureus subsp. aureus N315 Site: position = -69 score = 5.54845 sequence = TGAGTCGTAAACATTACTGTTTA Gene: SA1385: Zinc ABC transporter, ATP-binding protein ZnuC	* Staphylococcus capitis SK14 Site: position = -66 score = 6.14233 sequence = TTAGTCGTAAACATTACTATTTA Gene: STACA0001_1794: Zinc ABC transporter, ATP-binding protein ZnuC	* Staphylococcus epidermidis ATCC 12228 Site: position = -58 score = 5.76501 sequence = ATAGTCGTAAACATTACTATTTA Gene: SE1243: Zinc ABC transporter, ATP-binding protein ZnuC	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -65 score = 6.17882 sequence = TTAATCGTAAGCATTACAATTTA Gene: Sca_1177: Zinc ABC transporter, ATP-binding protein ZnuC	* Staphylococcus haemolyticus JCSC1435 Site: position = -66 score = 6.18966 sequence = CAAGTCGTAAACATTACTATTTA Gene: SH1360: Zinc ABC transporter, ATP-binding protein ZnuC	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -66 score = 6.07766 sequence = TAATTCGGAAACATTACTATTTA Gene: SSP1200: Zinc ABC transporter, ATP-binding protein ZnuC	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1206: Zinc ABC transporter, ATP-binding protein ZnuC	Zinc ABC transporter, ATP-binding protein ZnuC
znuB	Staphylococcus aureus subsp. aureus N315 Gene: SA1384: Zinc ABC transporter, inner membrane permease protein ZnuB	Staphylococcus capitis SK14 Gene: STACA0001_1793: Zinc ABC transporter, inner membrane permease protein ZnuB	Staphylococcus epidermidis ATCC 12228 Gene: SE1242: Zinc ABC transporter, inner membrane permease protein ZnuB	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1176: Zinc ABC transporter, inner membrane permease protein ZnuB	Staphylococcus haemolyticus JCSC1435 Gene: SH1361: Zinc ABC transporter, inner membrane permease protein ZnuB	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1201: Zinc ABC transporter, inner membrane permease protein ZnuB	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1205: Zinc ABC transporter, inner membrane permease protein ZnuB	Zinc ABC transporter, inner membrane permease protein ZnuB
zur	Staphylococcus aureus subsp. aureus N315 Gene: SA1383: Zinc homeostasis transcriptional regulator Zur, Fur family	Staphylococcus capitis SK14 Gene: STACA0001_1792: Zinc homeostasis transcriptional regulator Zur, Fur family	Staphylococcus epidermidis ATCC 12228 Gene: SE1241: Zinc homeostasis transcriptional regulator Zur, Fur family	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1175: Zinc homeostasis transcriptional regulator Zur, Fur family	Staphylococcus haemolyticus JCSC1435 Gene: SH1362: Zinc homeostasis transcriptional regulator Zur, Fur family	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1202: Zinc homeostasis transcriptional regulator Zur, Fur family	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1204: Zinc homeostasis transcriptional regulator Zur, Fur family	Zinc homeostasis transcriptional regulator Zur, Fur family

CRON 2.
znuA2	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	* Staphylococcus epidermidis ATCC 12228 Site: position = -35 score = 6.14152 sequence = TAAAGCGTAACAATTTCGATTTA Site: position = -226 score = 6.82936 sequence = AAAAACGTAATTATTACGATTTA Gene: SE0193: Zinc ABC transporter, periplasmic-binding protein ZnuA	Staphylococcus carnosus subsp. carnosus TM300	* Staphylococcus haemolyticus JCSC1435 Site: position = -35 score = 6.40515 sequence = TAAAACGTAATGATTTTGATTTA Site: position = -188 score = 6.97268 sequence = CAAATCGTAATTATTACTATTTA Gene: SH0125: Zinc ABC transporter, periplasmic-binding protein ZnuA	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	Zinc ABC transporter, periplasmic-binding protein ZnuA

CRON 3.
zinT	* Staphylococcus aureus subsp. aureus N315 Site: position = -34 score = 6.64591 sequence = TAAAACGTAAAGATTACTATTTA Gene: SA2194: Candidate zinc-binding lipoprotein ZinT	* Staphylococcus capitis SK14 Site: position = -34 score = 7.2575 sequence = TAAATCGTAATAATTACTATTTA Gene: STACA0001_1070: Candidate zinc-binding lipoprotein ZinT	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	* Staphylococcus haemolyticus JCSC1435 Site: position = -34 score = 7.2575 sequence = TAAATCGTAATTATTACTATTTA Gene: SH0645: Candidate zinc-binding lipoprotein ZinT	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -36 score = 6.88018 sequence = TAAATCGTAACAATTACTATTTA Gene: SSP0490: Candidate zinc-binding lipoprotein ZinT	Macrococcus caseolyticus JCSC5402	Candidate zinc-binding lipoprotein ZinT

CRON 4.
yciC	* Staphylococcus aureus subsp. aureus N315 Site: position = -50 score = 6.41235 sequence = TAAAACGGAATTATTCCTATTTA Gene: SA0410: Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family	* Staphylococcus capitis SK14 Site: position = -43 score = 7.07246 sequence = TAAAACGTAATAATTACTATTTA Gene: STACA0001_1465: Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family	* Staphylococcus epidermidis ATCC 12228 Site: position = -43 score = 7.07246 sequence = TAAAACGTAATAATTACTATTTA Gene: SE2335: Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -58 score = 7.05958 sequence = TAAATCGTAATTATTACGATTAA Gene: Sca_1955: Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family	* Staphylococcus haemolyticus JCSC1435 Site: position = -44 score = 7.20669 sequence = TAAAACGTAATTATTACGATTTA Gene: SH0144: Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	* Macrococcus caseolyticus JCSC5402 Site: position = -35 score = 6.37494 sequence = TAAAACGTAATGATTACGAATTG Gene: MCCL_0991: Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family	Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family

CRON 5.
Sca_0100	Staphylococcus aureus subsp. aureus N315	* Staphylococcus capitis SK14 Site: position = -33 score = 6.13032 sequence = TAAATCGTAATAATTTCGATTGG Gene: STACA0001_0760: putative alkylmercury lyase	Staphylococcus epidermidis ATCC 12228	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -51 score = 6.063 sequence = TAAATCGAAATCATTACGCTTAA Gene: Sca_0100: putative alkylmercury lyase	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	putative alkylmercury lyase

CRON 6.
SA2370	* Staphylococcus aureus subsp. aureus N315 Site: position = -69 score = 7.39173 sequence = TAAATCGTAATTATTACGATTTA Gene: SA2370: hypothetical protein	Staphylococcus capitis SK14	* Staphylococcus epidermidis ATCC 12228 Site: position = -53 score = 6.82936 sequence = TAAATCGTAATAATTACGTTTTT Site: position = -244 score = 6.14152 sequence = TAAATCGAAATTGTTACGCTTTA Gene: SE0191: hypothetical protein	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -83 score = 6.44897 sequence = TAAAACATAACGATTACGATTTA Gene: Sca_1906: hypothetical protein	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	hypothetical protein
SA2369	Staphylococcus aureus subsp. aureus N315 Gene: SA2369: hypothetical protein	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228 Gene: SE0189: hypothetical protein	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1905: hypothetical protein	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	hypothetical protein
SA2368	Staphylococcus aureus subsp. aureus N315 Gene: SA2368: hypothetical protein	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228 Gene: SE0188: hypothetical protein	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1904: hypothetical protein	* Staphylococcus haemolyticus JCSC1435 Site: position = -101 score = 6.97268 sequence = TAAATAGTAATAATTACGATTTG Site: position = -254 score = 6.40515 sequence = TAAATCAAAATCATTACGTTTTA Gene: SH0124: hypothetical protein	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	hypothetical protein

CRON 7.
SA2203	* Staphylococcus aureus subsp. aureus N315 Site: position = -126 score = 6.94877 sequence = TAAATAGTAATGATTACGTTTTA Gene: SA2203: putative MFS family major facilitator transporter	* Staphylococcus capitis SK14 Site: position = -145 score = 7.2575 sequence = TAAATAGTAATTATTACGATTTA Gene: STACA0001_1062: putative MFS family major facilitator transporter	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	* Staphylococcus haemolyticus JCSC1435 Site: position = -120 score = 7.2575 sequence = TAAATAGTAATTATTACGATTTA Gene: SH0638: putative MFS family major facilitator transporter	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -168 score = 7.2575 sequence = TAAATAGTAATTATTACGATTTA Gene: SSP0485: putative MFS family major facilitator transporter	Macrococcus caseolyticus JCSC5402	putative MFS family major facilitator transporter

CRON 8.
SA0806	* Staphylococcus aureus subsp. aureus N315 Site: position = -42 score = 6.43897 sequence = TAAATCGTAACGATTACGCTTTA Gene: SA0806: hypothetical protein	* Staphylococcus capitis SK14 Site: position = -52 score = 6.83637 sequence = TAAATAGTAATTATTTCGATTTA Gene: STACA0001_0181: hypothetical protein	* Staphylococcus epidermidis ATCC 12228 Site: position = -42 score = 7.20669 sequence = TAAATCGTAATAATTACGTTTTA Gene: SE0639: hypothetical protein	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -36 score = 6.97059 sequence = TAAATCGAAATTATTACGATTTA Gene: Sca_0550: hypothetical protein	* Staphylococcus haemolyticus JCSC1435 Site: position = -42 score = 7.20669 sequence = TAAATCGTAATTATTACGTTTTA Gene: SH2006: hypothetical protein	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -40 score = 7.39173 sequence = TAAATCGTAATTATTACGATTTA Gene: SSP1830: hypothetical protein	Macrococcus caseolyticus JCSC5402	hypothetical protein

CRON 9.
rpsN2	* Staphylococcus aureus subsp. aureus N315 Site: position = -45 score = 7.1069 sequence = TAAATCGTAATAATTACGATTTG Gene: SA1171: 30S ribosomal protein S14	* Staphylococcus capitis SK14 Site: position = -42 score = 7.20669 sequence = TAAAACGTAATAATTACGATTTA Gene: STACA0001_1579: 30S ribosomal protein S14	* Staphylococcus epidermidis ATCC 12228 Site: position = -42 score = 6.92186 sequence = TAAAACGTAATTATTACGATTTG Gene: SE1018: 30S ribosomal protein S14	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -54 score = 6.68225 sequence = TAAATCGTAATAATTACGATTAT Gene: Sca_0977: 30S ribosomal protein S14	* Staphylococcus haemolyticus JCSC1435 Site: position = -43 score = 7.20669 sequence = TAAAACGTAATAATTACGATTTA Gene: SH1571: 30S ribosomal protein S14	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -43 score = 6.92186 sequence = TAAAACGTAATAATTACGATTTG Gene: SSP1421: 30S ribosomal protein S14	Macrococcus caseolyticus JCSC5402	30S ribosomal protein S14

CRON 10.
rpmG2	* Staphylococcus aureus subsp. aureus N315 Site: position = -38 score = 5.3535 sequence = TAAATCGTAAAGATTCCTAACAA Gene: SAS042: 50S ribosomal protein L33	* Staphylococcus capitis SK14 Site: position = -43 score = 5.31435 sequence = TAAATCGTAAGAATTCCTAACAA Gene: STACA0001_1578: 50S ribosomal protein L33	* Staphylococcus epidermidis ATCC 12228 Site: position = -43 score = 5.31435 sequence = TAAATCGTAAGAATTCCTAACAA Gene: SE1017: 50S ribosomal protein L33	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -227 score = 6.68225 sequence = ATAATCGTAATTATTACGATTTA Gene: Sca_0976: 50S ribosomal protein L33	* Staphylococcus haemolyticus JCSC1435 Site: position = -43 score = 6.46175 sequence = TAAATCGTAAGTATTCCTATTTA Gene: SH1572: 50S ribosomal protein L33	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -39 score = 7.07246 sequence = TAAAACGTAATAATTACTATTTA Gene: SSP1422: 50S ribosomal protein L33	Macrococcus caseolyticus JCSC5402	50S ribosomal protein L33

CRON 11.
znuA	Staphylococcus aureus subsp. aureus N315	* Staphylococcus capitis SK14 Site: position = -36 score = 5.3395 sequence = ATAAACGAAATAATTACGCTTTG Gene: STACA0001_0989: Zinc ABC transporter, periplasmic-binding protein ZnuA	Staphylococcus epidermidis ATCC 12228 Gene: SE2068: Zinc ABC transporter, periplasmic-binding protein ZnuA	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -40 score = 6.27476 sequence = TAAACCATAATGATTACGATTTG Gene: Sca_1971: Zinc ABC transporter, periplasmic-binding protein ZnuA	* Staphylococcus haemolyticus JCSC1435 Site: position = -34 score = 5.37094 sequence = AAAAACGAATTTATTACGTTTTG Gene: SH0551: Zinc ABC transporter, periplasmic-binding protein ZnuA	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -35 score = 5.18587 sequence = TTTAACGAAATAATTTCGATTTG Gene: SSP0388: Zinc ABC transporter, periplasmic-binding protein ZnuA	* Macrococcus caseolyticus JCSC5402 Site: position = -35 score = 5.72088 sequence = TAAAACGTAACGATTACGAAATA Site: position = -168 score = 6.37494 sequence = CAATTCGTAATCATTACGTTTTA Gene: MCCL_0992: Zinc ABC transporter, periplasmic-binding protein ZnuA	Zinc ABC transporter, periplasmic-binding protein ZnuA

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Zur - Staphylococcaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --