Regulog BirA - Staphylococcaceae

Properties
Regulator type:	Transcription factor
Regulator family:	BirA
Regulation mode:	repressor
Biological process:	Biotin biosynthesis
Effector:	Biotin
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 21 sites [see more]

Member of regulog collections

By taxonomy - Staphylococcaceae
By trascription factor - BirA
By TF family - BirA
By effector - Biotin
By pathway - Biotin biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Staphylococcus aureus subsp. aureus N315	12	3
Staphylococcus capitis SK14	8	3
Staphylococcus epidermidis ATCC 12228	12	4
Staphylococcus carnosus subsp. carnosus TM300	7	4
Staphylococcus haemolyticus JCSC1435	7	3
Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	6	2
Macrococcus caseolyticus JCSC5402	2	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes								Function

CRON 1.
yhfT	* Staphylococcus aureus subsp. aureus N315 Site: position = -48 score = 7.06964 sequence = AATGTTAACAAGATGTATTTTAAAGTTTACATT Gene: SA0533: putative long chain fatty acid-CoA ligase	* Staphylococcus capitis SK14 Site: position = -43 score = 7.17092 sequence = AATGTTAACATATTTATAAATATAGTTTACATA Gene: STACA0001_0458: putative long chain fatty acid-CoA ligase	* Staphylococcus epidermidis ATCC 12228 Site: position = -44 score = 7.05411 sequence = AATGTAAACATAATTATATAAAGTGTTTACAAA Gene: SE0344: putative long chain fatty acid-CoA ligase	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2089: putative long chain fatty acid-CoA ligase	* Staphylococcus haemolyticus JCSC1435 Site: position = -55 score = 7.56508 sequence = AATGTTAACATAATATAAAATAAAGTTAACATT Gene: SH2418: putative long chain fatty acid-CoA ligase	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -49 score = 6.58307 sequence = AATGTTAACATATTTGTTATGAAGGTTAACAAA Gene: SSP2146: putative long chain fatty acid-CoA ligase	Macrococcus caseolyticus JCSC5402	putative long chain fatty acid-CoA ligase
SE0345	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228 Gene: SE0345: hypothetical protein	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	hypothetical protein
yhfS	Staphylococcus aureus subsp. aureus N315 Gene: SA0534: putative acetyl-CoA c-acetyltransferase	Staphylococcus capitis SK14 Gene: STACA0001_0457: putative acetyl-CoA c-acetyltransferase	Staphylococcus epidermidis ATCC 12228 Gene: SE0346: putative acetyl-CoA c-acetyltransferase	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2088: putative acetyl-CoA c-acetyltransferase	Staphylococcus haemolyticus JCSC1435 Gene: SH2417: putative acetyl-CoA c-acetyltransferase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP2145: putative acetyl-CoA c-acetyltransferase	Macrococcus caseolyticus JCSC5402	putative acetyl-CoA c-acetyltransferase
SA0535	Staphylococcus aureus subsp. aureus N315 Gene: SA0535: hypothetical protein	Staphylococcus capitis SK14 Gene: STACA0001_0456: protein VraC	Staphylococcus epidermidis ATCC 12228 Gene: SE0347: hypothetical protein	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2087: hypothetical protein	Staphylococcus haemolyticus JCSC1435 Gene: SH2416: hypothetical protein	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP2144: hypothetical protein	Macrococcus caseolyticus JCSC5402	hypothetical protein
SA0536	Staphylococcus aureus subsp. aureus N315 Gene: SA0536: hypothetical protein	Staphylococcus capitis SK14 Gene: STACA0001_0455: conserved hypothetical protein	Staphylococcus epidermidis ATCC 12228 Gene: SE0348: hypothetical protein	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435 Gene: SH2415: hypothetical protein	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP2143: hypothetical protein	Macrococcus caseolyticus JCSC5402	hypothetical protein

CRON 2.
pycA	Staphylococcus aureus subsp. aureus N315 Gene: SA0963: pyruvate carboxylase	Staphylococcus capitis SK14 Gene: STACA0001_2249: pyruvate carboxylase	Staphylococcus epidermidis ATCC 12228 Gene: SE0813: pyruvate carboxylase	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -367 score = 7.19291 sequence = AATGTAAACTTAAAAATAAATAAAATTAACAAT Gene: Sca_0740: pyruvate carboxylase	Staphylococcus haemolyticus JCSC1435 Gene: SH1838: pyruvate carboxylase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP1675: pyruvate carboxylase	Macrococcus caseolyticus JCSC5402 Gene: MCCL_0729: pyruvate carboxylase	pyruvate carboxylase

CRON 3.
bioY	* Staphylococcus aureus subsp. aureus N315 Site: position = -75 score = 7.50757 sequence = ATTGTAAACTTTTCATTTCTTAAAGTTTACAAT Gene: SA2077: biotin transporter BioY	* Staphylococcus capitis SK14 Site: position = -70 score = 7.78149 sequence = TATGTAAACTTTTTATTTCTTAAAGTTTACATT Gene: STACA0001_1211: biotin transporter BioY	* Staphylococcus epidermidis ATCC 12228 Site: position = -70 score = 6.9213 sequence = ATTGTAAACTTTCCATTCATAAAAGTTTACAAG Gene: SE1856: biotin transporter BioY	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -75 score = 7.28465 sequence = AATGTAAACTTTTAGTAAATTCAAGTTAACAAT Gene: Sca_1775: biotin transporter BioY	* Staphylococcus haemolyticus JCSC1435 Site: position = -69 score = 8.17293 sequence = AATGTAAACTTTTTATTTTATAAAGTTTACATT Gene: SH0770: biotin transporter BioY	* Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Site: position = -67 score = 8.11648 sequence = AATGTAAACTTTTTATTTTTTAAAGTTTACATT Gene: SSP0625: biotin transporter BioY	* Macrococcus caseolyticus JCSC5402 Site: position = -75 score = 6.67416 sequence = ATTGTTAACTTTTTGTACTAAAAGGTTAACGAA Gene: MCCL_0134: biotin transporter BioY	biotin transporter BioY
SA2076	Staphylococcus aureus subsp. aureus N315 Gene: SA2076: putative acetyltransferase	Staphylococcus capitis SK14 Gene: STACA0001_1212: putative acetyltransferase	Staphylococcus epidermidis ATCC 12228 Gene: SE1855: putative acetyltransferase	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_1774: putative acetyltransferase	Staphylococcus haemolyticus JCSC1435 Gene: SH0771: putative acetyltransferase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 Gene: SSP0626: putative acetyltransferase	Macrococcus caseolyticus JCSC5402 Gene: MCCL_1694: putative acetyltransferase	putative acetyltransferase

CRON 4.
bioD	* Staphylococcus aureus subsp. aureus N315 Site: position = -55 score = 7.94585 sequence = AATGTAAACTTATTAATTATAAAAGTTTACATT Gene: SA2215: dethiobiotin synthetase	Staphylococcus capitis SK14	* Staphylococcus epidermidis ATCC 12228 Site: position = -55 score = 7.7403 sequence = AATGTAAACTTTAAAATGTAATAAGTTTACATT Gene: SE0179: dethiobiotin synthetase	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2224: putative dethiobiotin synthetase	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	dethiobiotin synthetase
bioA	Staphylococcus aureus subsp. aureus N315 Gene: SA2214: adenosylmethionine-8-amino-7-oxononanoate aminotransferase	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228 Gene: SE0180: adenosylmethionine-8-amino-7-oxononanoate aminotransferase	Staphylococcus carnosus subsp. carnosus TM300 Gene: Sca_2223: putative adenosylmethionine-8-amino-7-oxononanoate aminotransferase	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	adenosylmethionine-8-amino-7-oxononanoate aminotransferase
bioB	Staphylococcus aureus subsp. aureus N315 Gene: SA2213: biotin synthase	* Staphylococcus capitis SK14 Site: position = -87 score = 7.99118 sequence = AATGTAAACTTATAAATATATAAAGTTTACATT Gene: STACA0001_0034: biotin synthase	* Staphylococcus epidermidis ATCC 12228 Site: position = -110 score = 7.88128 sequence = AATGTAAACTTATAAATATATAAAGTTTACAAT Gene: SE0234: biotin synthase	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -63 score = 7.35149 sequence = AATGTTAACTATATAAAAAAATAAGTTAACAAT Gene: Sca_2002: putative biotin synthase	* Staphylococcus haemolyticus JCSC1435 Site: position = -75 score = 7.96501 sequence = AATGTAAACTTATTTATATATAAAGTTTACATT Gene: SH0269: biotin synthase	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	* Macrococcus caseolyticus JCSC5402 Site: position = -76 score = 6.75088 sequence = ATTGTTAACTTATATTCAAAATTAGTTTACAAT Gene: MCCL_0376: biotin synthase	biotin synthase
bioF	Staphylococcus aureus subsp. aureus N315 Gene: SA2212: hypothetical protein	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228 Gene: SE0181: 8-amino-7-oxononanoate synthase	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	hypothetical protein
bioW	Staphylococcus aureus subsp. aureus N315 Gene: SA2211: hypothetical protein	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228 Gene: SE0182: 6-carboxyhexanoate--CoA ligase	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	hypothetical protein
bioX	Staphylococcus aureus subsp. aureus N315 Gene: SA2210: hypothetical protein	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	hypothetical protein
bioY	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14	Staphylococcus epidermidis ATCC 12228	* Staphylococcus carnosus subsp. carnosus TM300 Site: position = -73 score = 7.97202 sequence = AATGTAAACTTATAAAAATTAAAAGTTTACATT Gene: Sca_2225: putative biotin synthase	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	putative biotin synthase
SA2076	Staphylococcus aureus subsp. aureus N315	Staphylococcus capitis SK14 Gene: STACA0001_0035: hypothetical protein	Staphylococcus epidermidis ATCC 12228	Staphylococcus carnosus subsp. carnosus TM300	Staphylococcus haemolyticus JCSC1435	Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305	Macrococcus caseolyticus JCSC5402	hypothetical protein

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog BirA - Staphylococcaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --