Regulog PyrR - Clostridiaceae

Properties
Regulator type:	RNA regulatory element
Name:	PyrR
RFAM:	RF00515
Regulation mode:
Biological process:	Pyrimidine metabolism
Effector:	PyrR
Phylum:	Firmicutes

Member of regulog collections

By taxonomy - Clostridiaceae
By RNA motif - PyrR
By effector - PyrR
By pathway - Pyrimidine metabolism

Statistics of regulated genes
Genome	Genes	Operons
Clostridium kluyveri DSM 555	11	3
Clostridium sp. SS2/1
Clostridium cellulolyticum H10	9	2
Clostridium phytofermentans ISDg
Clostridium tetani E88	3	3
Clostridium acetobutylicum ATCC 824	8	3
Clostridium botulinum A str. ATCC 3502	12	5
Clostridium novyi NT	9	3
Clostridium perfringens ATCC 13124	10	4
Clostridium difficile 630	9	2
Clostridium beijerincki NCIMB 8052	10	3
Clostridium sp. OhILAs	7	3
Clostridium sp. L2-50
Clostridium scindens ATCC 35704
Clostridium nexile DSM 1787
Clostridium leptum DSM 753
Clostridium hiranonis DSM 13275	6	2
Clostridium butyricum 5521	12	4
Clostridium bolteae ATCC BAA-613
Clostridium bartlettii DSM 16795	9	3

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																					Function

CRON 1.
pyrR	* Clostridium kluyveri DSM 555 Site: position = -119 score = 42.7 sequence = AATATCCTTTAAAAT... Gene: CKL_1201: Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR	Clostridium sp. SS2/1	* Clostridium cellulolyticum H10 Site: position = -200 score = 45.53 sequence = TTACCTTTAAATTAG... Gene: Ccel_0611: Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR	Clostridium phytofermentans ISDg	* Clostridium tetani E88 Site: position = -91 score = 41.3 sequence = TAAATCCTTTAAAGT... Gene: CTC01613: Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR	Clostridium acetobutylicum ATCC 824 Gene: CAC2113: Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR	2 Clostridium botulinum A str. ATCC 3502* Site: position = -119 score = 29.81 sequence = AAAGCCCTTTAAATG... Gene: CBO2821: Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR Site: position = -237 score = 42.1 sequence = TTACCTTTAAAATGA... Gene: CBO1478: Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR	Clostridium novyi NT Gene: NT01CX_1953: Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR	Clostridium perfringens ATCC 13124 Gene: CPF_2103: Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR	Clostridium difficile 630 Gene: CD2595: Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1596: Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR	Clostridium sp. OhILAs Gene: Clos_1418: Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01119: Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR	Clostridium butyricum 5521 Gene: CBY_0086: Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR	Clostridium bolteae ATCC BAA-613	* Clostridium bartlettii DSM 16795 Site: position = -156 score = 24.33 sequence = ATATACCTTTAATTG... Gene: CLOBAR_01469: Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR	Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR
pyrB	* Clostridium kluyveri DSM 555 Site: position = -151 score = 45.53 sequence = CTGAACCTTTAAGAC... Gene: CKL_3361: Aspartate carbamoyltransferase (EC 2.1.3.2)	Clostridium sp. SS2/1 Gene: CLOSS21_01646: Aspartate carbamoyltransferase (EC 2.1.3.2)	Clostridium cellulolyticum H10 Gene: Ccel_0612: Aspartate carbamoyltransferase (EC 2.1.3.2)	Clostridium phytofermentans ISDg Gene: null: Aspartate carbamoyltransferase (EC 2.1.3.2)	* Clostridium tetani E88 Site: position = -146 score = 54.53 sequence = TAAAGCCTTTAAAAA... Gene: CTC02384: Aspartate carbamoyltransferase (EC 2.1.3.2)	* Clostridium acetobutylicum ATCC 824 Site: position = -150 score = 50.43 sequence = ATAAACCTTTAATTA... Gene: CAC2654: Aspartate carbamoyltransferase (EC 2.1.3.2)	* Clostridium botulinum A str. ATCC 3502 Site: position = -195 score = 37.0 sequence = TAAGACCTTTAAAAT... Gene: CBO3241: Aspartate carbamoyltransferase (EC 2.1.3.2)	* Clostridium novyi NT Site: position = -180 score = 33.25 sequence = GCGTGCCTTTAATTC... Gene: NT01CX_0395: Aspartate carbamoyltransferase (EC 2.1.3.2)	* Clostridium perfringens ATCC 13124 Site: position = -180 score = 46.94 sequence = AATAACCTTTAAATT... Gene: CPF_1387: Aspartate carbamoyltransferase (EC 2.1.3.2)	* Clostridium difficile 630 Site: position = -46 score = 27.81 sequence = ATACTTTTAATTTTA... Gene: CD0184: Aspartate carbamoyltransferase (EC 2.1.3.2)	* Clostridium beijerincki NCIMB 8052 Site: position = -165 score = 37.43 sequence = TAACCTTTAATTTGA... Gene: Cbei_1000: Aspartate carbamoyltransferase (EC 2.1.3.2)	* Clostridium sp. OhILAs Site: position = -94 score = 44.7 sequence = TTACCTTTAAATTAG... Gene: Clos_2188: Aspartate carbamoyltransferase (EC 2.1.3.2)	Clostridium sp. L2-50 Gene: CLOL250_01287: Aspartate carbamoyltransferase (EC 2.1.3.2)	Clostridium scindens ATCC 35704 Gene: CLOSCI_00682: Aspartate carbamoyltransferase (EC 2.1.3.2)	Clostridium nexile DSM 1787 Gene: CLONEX_01423: Aspartate carbamoyltransferase (EC 2.1.3.2)	Clostridium leptum DSM 753 Gene: CLOLEP_01555: Aspartate carbamoyltransferase (EC 2.1.3.2)	* Clostridium hiranonis DSM 13275 Site: position = -47 score = 25.16 sequence = ATAGCTTTAAATTCG... Gene: CLOHIR_00048: Aspartate carbamoyltransferase (EC 2.1.3.2)	* Clostridium butyricum 5521 Site: position = -158 score = 37.04 sequence = AATAACCTTTAATTT... Gene: CBY_2768: Aspartate carbamoyltransferase (EC 2.1.3.2)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_04681: Aspartate carbamoyltransferase (EC 2.1.3.2)	* Clostridium bartlettii DSM 16795 Site: position = -47 score = 33.05 sequence = AATAACTTTTAATTT... Gene: CLOBAR_00677: Aspartate carbamoyltransferase (EC 2.1.3.2)	Aspartate carbamoyltransferase (EC 2.1.3.2)
pyrC	2 Clostridium kluyveri DSM 555 Gene: CKL_3359: Dihydroorotase (EC 3.5.2.3) Gene: CKL_2401: Dihydroorotase (EC 3.5.2.3)	Clostridium sp. SS2/1 Gene: CLOSS21_02222: Dihydroorotase (EC 3.5.2.3)	Clostridium cellulolyticum H10 Gene: Ccel_0613: Dihydroorotase (EC 3.5.2.3)	Clostridium phytofermentans ISDg Gene: null: Dihydroorotase (EC 3.5.2.3)	Clostridium tetani E88 Gene: CTC02382: Dihydroorotase (EC 3.5.2.3)	Clostridium acetobutylicum ATCC 824 Gene: CAC0519: Dihydroorotase (EC 3.5.2.3)	Clostridium botulinum A str. ATCC 3502 Gene: CBO3239: Dihydroorotase (EC 3.5.2.3)	Clostridium novyi NT Gene: NT01CX_0394: Dihydroorotase (EC 3.5.2.3)	Clostridium perfringens ATCC 13124 Gene: CPF_1385: Dihydroorotase (EC 3.5.2.3)	Clostridium difficile 630 Gene: CD1526: Dihydroorotase (EC 3.5.2.3)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1002: Dihydroorotase (EC 3.5.2.3)	* Clostridium sp. OhILAs Site: position = -494 score = 33.47 sequence = GTCGACCTTTAAGAA... Gene: Clos_2194: Dihydroorotase (EC 3.5.2.3)	Clostridium sp. L2-50 Gene: CLOL250_02240: Dihydroorotase (EC 3.5.2.3)	Clostridium scindens ATCC 35704 Gene: CLOSCI_04057: Dihydroorotase (EC 3.5.2.3)	Clostridium nexile DSM 1787 Gene: CLONEX_00216: Dihydroorotase (EC 3.5.2.3)	2 Clostridium leptum DSM 753 Gene: CLOLEP_01179: Dihydroorotase (EC 3.5.2.3) Gene: CLOLEP_00364: Dihydroorotase (EC 3.5.2.3)	Clostridium hiranonis DSM 13275 Gene: CLOHIR_01356: Dihydroorotase (EC 3.5.2.3)	Clostridium butyricum 5521 Gene: CBY_2766: Dihydroorotase (EC 3.5.2.3)	2 Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_00063: Dihydroorotase (EC 3.5.2.3) Gene: CLOBOL_01666: Dihydroorotase (EC 3.5.2.3)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01636: Dihydroorotase (EC 3.5.2.3)	Dihydroorotase (EC 3.5.2.3)
pyrF	Clostridium kluyveri DSM 555 Gene: CKL_3358: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	Clostridium sp. SS2/1 Gene: CLOSS21_00752: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	Clostridium cellulolyticum H10 Gene: Ccel_0614: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	Clostridium phytofermentans ISDg Gene: null: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	Clostridium tetani E88 Gene: CTC02381: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	Clostridium acetobutylicum ATCC 824 Gene: CAC2652: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	Clostridium botulinum A str. ATCC 3502 Gene: CBO3238: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	Clostridium novyi NT Gene: NT01CX_0393: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	Clostridium perfringens ATCC 13124 Gene: CPF_1384: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	* Clostridium difficile 630 Site: position = -146 score = 52.01 sequence = AAAGTCTTTTAAACT... Site: position = -261 score = 32.62 sequence = AAATTCCTTAAAGTA... Gene: CD3592: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1003: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	Clostridium sp. OhILAs Gene: Clos_2193: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	Clostridium sp. L2-50 Gene: CLOL250_01418: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	Clostridium scindens ATCC 35704 Gene: CLOSCI_04058: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	Clostridium nexile DSM 1787 Gene: CLONEX_00214: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	Clostridium leptum DSM 753 Gene: CLOLEP_00363: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	* Clostridium hiranonis DSM 13275 Site: position = -106 score = 47.31 sequence = AGTCTTTTAAGCTAG... Gene: CLOHIR_02208: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	Clostridium butyricum 5521 Gene: CBY_2765: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_03549: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	* Clostridium bartlettii DSM 16795 Site: position = -141 score = 54.61 sequence = AAGTCTTTTAAAATA... Gene: CLOBAR_00209: Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)	Orotidine 5'-phosphate decarboxylase (EC 4.1.1.23)
carA	* Clostridium kluyveri DSM 555 Site: position = -216 score = 31.49 sequence = TACACTTTAAATTGG... Gene: CKL_0649: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)	Clostridium sp. SS2/1 Gene: CLOSS21_00313: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)	Clostridium cellulolyticum H10 Gene: Ccel_0615: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)	Clostridium phytofermentans ISDg Gene: null: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)	Clostridium tetani E88	* Clostridium acetobutylicum ATCC 824 Site: position = -422 score = 46.91 sequence = ATATACCTTTAATGA... Gene: CAC2645: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)	Clostridium botulinum A str. ATCC 3502	* Clostridium novyi NT Site: position = -245 score = 50.86 sequence = ATTAACCTTTAATTT... Site: position = -365 score = 35.64 sequence = AAAGTCCTTTAAGGT... Gene: NT01CX_0383: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)	* Clostridium perfringens ATCC 13124 Site: position = -283 score = 29.2 sequence = AATACACTTTAAATT... Gene: CPF_2898: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)	2 Clostridium difficile 630 Gene: CD3589: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) Gene: CD3591: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)	* Clostridium beijerincki NCIMB 8052 Site: position = -232 score = 33.88 sequence = TACACTTTAACTTGG... Gene: Cbei_0028: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_00038: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)	Clostridium scindens ATCC 35704 Gene: CLOSCI_02024: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)	Clostridium nexile DSM 1787	2 Clostridium leptum DSM 753 Gene: CLOLEP_02637: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) Gene: CLOLEP_02636: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)	2 Clostridium hiranonis DSM 13275 Gene: CLOHIR_01717: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5) Gene: CLOHIR_02209: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)	* Clostridium butyricum 5521 Site: position = -225 score = 29.02 sequence = GATGCACTTTAACTT... Gene: CBY_2289: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_02798: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00210: Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)	Carbamoyl-phosphate synthase small chain (EC 6.3.5.5)
carB	Clostridium kluyveri DSM 555 Gene: CKL_0650: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)	Clostridium sp. SS2/1 Gene: CLOSS21_00314: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)	Clostridium cellulolyticum H10 Gene: Ccel_0616: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)	Clostridium phytofermentans ISDg Gene: null: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824 Gene: CAC2644: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)	Clostridium botulinum A str. ATCC 3502	Clostridium novyi NT Gene: NT01CX_0382: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)	Clostridium perfringens ATCC 13124 Gene: CPF_2897: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)	2 Clostridium difficile 630 Gene: CD3588: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) Gene: CD3590: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_0029: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_00039: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)	Clostridium scindens ATCC 35704 Gene: CLOSCI_02023: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)	Clostridium nexile DSM 1787	Clostridium leptum DSM 753 Gene: CLOLEP_02638: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)	2 Clostridium hiranonis DSM 13275 Gene: CLOHIR_01718: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5) Gene: CLOHIR_02210: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)	Clostridium butyricum 5521 Gene: CBY_2288: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_02797: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00211: Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)	Carbamoyl-phosphate synthase large chain (EC 6.3.5.5)
pyrK	Clostridium kluyveri DSM 555 Gene: CKL_3357: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium sp. SS2/1 Gene: CLOSS21_00751: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium cellulolyticum H10 Gene: Ccel_0617: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium phytofermentans ISDg Gene: null: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium tetani E88 Gene: CTC02380: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium acetobutylicum ATCC 824 Gene: CAC2651: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium botulinum A str. ATCC 3502 Gene: CBO3237: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium novyi NT Gene: NT01CX_0392: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium perfringens ATCC 13124 Gene: CPF_1383: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium difficile 630 Gene: CD0185: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1004: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium sp. OhILAs Gene: Clos_2192: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium sp. L2-50 Gene: CLOL250_01419: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium scindens ATCC 35704 Gene: CLOSCI_04059: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium nexile DSM 1787 Gene: CLONEX_00213: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium leptum DSM 753 Gene: CLOLEP_00362: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00049: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium butyricum 5521 Gene: CBY_2764: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_03548: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00676: Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)	Dihydroorotate dehydrogenase electron transfer subunit (EC 1.3.3.1)
pyrD	2 Clostridium kluyveri DSM 555 Gene: CKL_3356: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1) Gene: CKL_2399: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Clostridium sp. SS2/1 Gene: CLOSS21_00750: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Clostridium cellulolyticum H10 Gene: Ccel_0618: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Clostridium phytofermentans ISDg Gene: null: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Clostridium tetani E88 Gene: CTC02379: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Clostridium acetobutylicum ATCC 824 Gene: CAC2650: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Clostridium botulinum A str. ATCC 3502 Gene: CBO3236: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Clostridium novyi NT Gene: NT01CX_0391: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Clostridium perfringens ATCC 13124 Gene: CPF_1382: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Clostridium difficile 630 Gene: CD0186: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1005: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	2 Clostridium sp. OhILAs Gene: Clos_2455: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1) Gene: Clos_2191: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	2 Clostridium sp. L2-50 Gene: CLOL250_01420: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1) Gene: CLOL250_00148: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Clostridium scindens ATCC 35704 Gene: CLOSCI_04060: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Clostridium nexile DSM 1787 Gene: CLONEX_00212: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Clostridium leptum DSM 753 Gene: CLOLEP_00361: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Clostridium hiranonis DSM 13275 Gene: CLOHIR_00050: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Clostridium butyricum 5521 Gene: CBY_2763: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_03547: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00675: Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)	Dihydroorotate dehydrogenase, catalytic subunit (EC 1.3.3.1)
pyrI	Clostridium kluyveri DSM 555 Gene: CKL_3360: Aspartate carbamoyltransferase regulatory chain (PyrI)	Clostridium sp. SS2/1 Gene: CLOSS21_01645: Aspartate carbamoyltransferase regulatory chain (PyrI)	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: null: Aspartate carbamoyltransferase regulatory chain (PyrI)	Clostridium tetani E88 Gene: CTC02383: Aspartate carbamoyltransferase regulatory chain (PyrI)	Clostridium acetobutylicum ATCC 824 Gene: CAC2653: Aspartate carbamoyltransferase regulatory chain (PyrI)	Clostridium botulinum A str. ATCC 3502 Gene: CBO3240: Aspartate carbamoyltransferase regulatory chain (PyrI)	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1001: Aspartate carbamoyltransferase regulatory chain (PyrI)	Clostridium sp. OhILAs	Clostridium sp. L2-50 Gene: CLOL250_01288: Aspartate carbamoyltransferase regulatory chain (PyrI)	Clostridium scindens ATCC 35704 Gene: CLOSCI_00683: Aspartate carbamoyltransferase regulatory chain (PyrI)	Clostridium nexile DSM 1787 Gene: CLONEX_01422: Aspartate carbamoyltransferase regulatory chain (PyrI)	Clostridium leptum DSM 753 Gene: CLOLEP_01556: Aspartate carbamoyltransferase regulatory chain (PyrI)	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_2767: Aspartate carbamoyltransferase regulatory chain (PyrI)	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_04682: Aspartate carbamoyltransferase regulatory chain (PyrI)	Clostridium bartlettii DSM 16795	Aspartate carbamoyltransferase regulatory chain (PyrI)
pyrE	2 Clostridium kluyveri DSM 555 Gene: CKL_3355: Orotate phosphoribosyltransferase (EC 2.4.2.10) Gene: CKL_2202: Orotate phosphoribosyltransferase (EC 2.4.2.10)	Clostridium sp. SS2/1 Gene: CLOSS21_00748: Orotate phosphoribosyltransferase (EC 2.4.2.10)	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg Gene: null: Orotate phosphoribosyltransferase (EC 2.4.2.10)	Clostridium tetani E88 Gene: CTC02378: Orotate phosphoribosyltransferase (EC 2.4.2.10)	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO3235: Orotate phosphoribosyltransferase (EC 2.4.2.10)	Clostridium novyi NT Gene: NT01CX_0390: Orotate phosphoribosyltransferase (EC 2.4.2.10)	Clostridium perfringens ATCC 13124 Gene: CPF_1381: Orotate phosphoribosyltransferase (EC 2.4.2.10)	Clostridium difficile 630 Gene: CD0187: Orotate phosphoribosyltransferase (EC 2.4.2.10)	Clostridium beijerincki NCIMB 8052 Gene: Cbei_1006: Orotate phosphoribosyltransferase (EC 2.4.2.10)	Clostridium sp. OhILAs Gene: Clos_2190: Orotate phosphoribosyltransferase (EC 2.4.2.10)	Clostridium sp. L2-50 Gene: CLOL250_01620: Orotate phosphoribosyltransferase (EC 2.4.2.10)	3 Clostridium scindens ATCC 35704 Gene: CLOSCI_00394: Orotate phosphoribosyltransferase (EC 2.4.2.10) Gene: CLOSCI_00395: Orotate phosphoribosyltransferase (EC 2.4.2.10) Gene: CLOSCI_04061: Orotate phosphoribosyltransferase (EC 2.4.2.10)	Clostridium nexile DSM 1787	2 Clostridium leptum DSM 753 Gene: CLOLEP_03080: Orotate phosphoribosyltransferase (EC 2.4.2.10) Gene: CLOLEP_02037: Orotate phosphoribosyltransferase (EC 2.4.2.10)	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_2762: Orotate phosphoribosyltransferase (EC 2.4.2.10)	2 Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_03546: Orotate phosphoribosyltransferase (EC 2.4.2.10) Gene: CLOBOL_02853: Orotate phosphoribosyltransferase (EC 2.4.2.10)	Clostridium bartlettii DSM 16795 Gene: CLOBAR_00674: Orotate phosphoribosyltransferase (EC 2.4.2.10)	Orotate phosphoribosyltransferase (EC 2.4.2.10)
codB	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88	Clostridium acetobutylicum ATCC 824	* Clostridium botulinum A str. ATCC 3502 Site: position = -197 score = 37.75 sequence = TAGTACCTTTAAAAT... Gene: CBO2073: Cytosine/purine/uracil/thiamine/allantoin permease family protein	Clostridium novyi NT	Clostridium perfringens ATCC 13124	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_2458: Cytosine/purine/uracil/thiamine/allantoin permease family protein	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	* Clostridium butyricum 5521 Site: position = -231 score = 29.84 sequence = AGTCCTTTAAGTTAT... Gene: CBY_1339: Cytosine/purine/uracil/thiamine/allantoin permease family protein	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Cytosine/purine/uracil/thiamine/allantoin permease family protein
codA	Clostridium kluyveri DSM 555	Clostridium sp. SS2/1	Clostridium cellulolyticum H10	Clostridium phytofermentans ISDg	Clostridium tetani E88 Gene: CTC01883: Cytosine deaminase (EC 3.5.4.1)	Clostridium acetobutylicum ATCC 824	Clostridium botulinum A str. ATCC 3502 Gene: CBO2072: Cytosine deaminase (EC 3.5.4.1)	Clostridium novyi NT	Clostridium perfringens ATCC 13124 Gene: CPF_0750: Cytosine deaminase (EC 3.5.4.1)	Clostridium difficile 630	Clostridium beijerincki NCIMB 8052	Clostridium sp. OhILAs Gene: Clos_2457: Cytosine deaminase (EC 3.5.4.1)	Clostridium sp. L2-50	Clostridium scindens ATCC 35704	Clostridium nexile DSM 1787	Clostridium leptum DSM 753	Clostridium hiranonis DSM 13275	Clostridium butyricum 5521 Gene: CBY_1340: Cytosine deaminase (EC 3.5.4.1)	Clostridium bolteae ATCC BAA-613	Clostridium bartlettii DSM 16795	Cytosine deaminase (EC 3.5.4.1)
pyrP	Clostridium kluyveri DSM 555 Gene: CKL_1200: Uracil permease	Clostridium sp. SS2/1	* Clostridium cellulolyticum H10 Site: position = -202 score = 59.58 sequence = AAACTTTTAAATTAG... Gene: Ccel_0485: Uracil permease	Clostridium phytofermentans ISDg Gene: null: Uracil permease	* Clostridium tetani E88 Site: position = -21 score = 30.24 sequence = ATATACTTTTAAATT... Gene: CTC01612: Uracil permease	* Clostridium acetobutylicum ATCC 824 Site: position = -47 score = 35.94 sequence = GAGGTACTTTTAATA... Gene: CAC2112: Uracil permease	* Clostridium botulinum A str. ATCC 3502 Site: position = -44 score = 27.26 sequence = GCATCTTTTAAAATA... Gene: CBO1479: Uracil permease	* Clostridium novyi NT Site: position = -215 score = 55.44 sequence = GATAATCTTTAATAC... Site: position = -86 score = 43.77 sequence = GATAACTTTTTAAAT... Gene: NT01CX_0192: Uracil permease	2 Clostridium perfringens ATCC 13124* Site: position = -207 score = 30.58 sequence = ACTATTCTTTAAAGA... Site: position = -84 score = 38.13 sequence = TTTACCTTTTTAAAT... Gene: CPF_1422: Uracil permease Site: position = -47 score = 26.12 sequence = AAACTTTTAATTTAG... Gene: CPF_1756: Uracil permease	Clostridium difficile 630 Gene: CD2594: Uracil permease	* Clostridium beijerincki NCIMB 8052 Site: position = -38 score = 29.37 sequence = TTTTAATTTAGTTCA... Gene: Cbei_1715: Uracil permease	3 Clostridium sp. OhILAs* Gene: Clos_0576: Uracil permease Gene: Clos_0867: Uracil permease Site: position = -96 score = 41.33 sequence = TAATACCTTTAAATC... Site: position = -241 score = 54.81 sequence = ATAAATCTTTAATGC... Gene: Clos_1951: Uracil permease	Clostridium sp. L2-50 Gene: CLOL250_02659: Uracil permease	Clostridium scindens ATCC 35704 Gene: CLOSCI_02483: Uracil permease	Clostridium nexile DSM 1787	Clostridium leptum DSM 753 Gene: CLOLEP_02867: Uracil permease	Clostridium hiranonis DSM 13275	2 Clostridium butyricum 5521* Site: position = -79 score = 27.06 sequence = AGACATATTTTAATT... Gene: CBY_3673: Uracil permease Gene: CBY_1449: Uracil permease	Clostridium bolteae ATCC BAA-613 Gene: CLOBOL_00010: Uracil permease	Clostridium bartlettii DSM 16795 Gene: CLOBAR_01468: Uracil permease	Uracil permease