Regulog NiaR - Bacillales

Properties
Regulator type:	Transcription factor
Regulator family:	NiaR
Regulation mode:	repressor
Biological process:	NAD biosynthesis
Effector:	Niacin
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 26 sites [see more]

Member of regulog collections

By trascription factor - NiaR
By taxonomy - Bacillales
By TF family - NiaR
By effector - Niacin
By pathway - NAD biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Bacillus subtilis subsp. subtilis str. 168	6	3
Bacillus amyloliquefaciens FZB42	6	3
Bacillus pumilus SAFR-032	3	1
Bacillus licheniformis DSM 13	6	3
Anoxybacillus flavithermus WK1	5	2
Geobacillus kaustophilus HTA426	6	3
Bacillus cereus ATCC 14579	6	3
Bacillus halodurans C-125	6	3
Bacillus clausii KSM-K16	6	3
Oceanobacillus iheyensis HTE831
Paenibacillus sp. JDR-2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes												Function

CRON 1.
niaP	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -63 score = 4.99963 sequence = ACAATGTGTAAAGACAGGTGTA Gene: BSU02950: Niacin transporter NiaP	* Bacillus amyloliquefaciens FZB42 Site: position = -61 score = 4.99963 sequence = ACAATGTGTAAAGACAGGTGTA Gene: RBAM_003210: Niacin transporter NiaP	Bacillus pumilus SAFR-032	* Bacillus licheniformis DSM 13 Site: position = -71 score = 5.35092 sequence = CAAAAGTGTAAAGACAGGTGTA Gene: BLi00841: Niacin transporter NiaP	Anoxybacillus flavithermus WK1	* Geobacillus kaustophilus HTA426 Site: position = -39 score = 5.22887 sequence = TAAATATGTCTTTACATTGATA Gene: GK3433: Niacin transporter NiaP	* Bacillus cereus ATCC 14579 Site: position = -37 score = 4.74066 sequence = ATGATGTGTAAAGACACCTGTG Gene: BC5418: Niacin transporter NiaP	Bacillus halodurans C-125	Bacillus clausii KSM-K16	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_2738: Niacin transporter NiaP	Niacin transporter NiaP

CRON 2.
nifS	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -83 score = 6.48385 sequence = TACACCTGTCTTGACACCTATA Gene: BSU27880: Cysteine desulfurase (EC 2.8.1.7)	* Bacillus amyloliquefaciens FZB42 Site: position = -84 score = 6.48385 sequence = TACACCTGTCTTGACACCTATA Gene: RBAM_024930: Cysteine desulfurase (EC 2.8.1.7)	Bacillus pumilus SAFR-032	* Bacillus licheniformis DSM 13 Site: position = -80 score = 6.6209 sequence = TACATGTGTCTTGACACCTATA Gene: BLi02915: Cysteine desulfurase (EC 2.8.1.7)	* Anoxybacillus flavithermus WK1 Site: position = -29 score = 4.38702 sequence = GACACCTATATTGACATATATT Site: position = -41 score = 5.45278 sequence = TCATACTGTCTTGACACCTATA Gene: Aflv_0702: Cysteine desulfurase (EC 2.8.1.7)	* Geobacillus kaustophilus HTA426 Site: position = -86 score = 6.06852 sequence = TTCACCTGTCTTGACATCTATA Gene: GK2602: Cysteine desulfurase (EC 2.8.1.7)	* Bacillus cereus ATCC 14579 Site: position = -127 score = 6.15591 sequence = TCCAACTGTCTTGACACCTATA Gene: BC4424: Cysteine desulfurase (EC 2.8.1.7)	* Bacillus halodurans C-125 Site: position = -102 score = 6.44612 sequence = TACATATGTCTTGACATCTATA Gene: BH1217: Cysteine desulfurase (EC 2.8.1.7)	* Bacillus clausii KSM-K16 Site: position = -73 score = 6.05862 sequence = TACAGTTGTCTTGTCACCTATA Gene: ABC1546: Cysteine desulfurase (EC 2.8.1.7)	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Cysteine desulfurase (EC 2.8.1.7)
niaR	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU27890: NAD biosynthesis transcription regulator, HTH_11 family	Bacillus amyloliquefaciens FZB42 Gene: RBAM_024940: NAD biosynthesis transcription regulator, HTH_11 family	Bacillus pumilus SAFR-032 Gene: BPUM_2429: NAD biosynthesis transcription regulator, HTH_11 family	Bacillus licheniformis DSM 13 Gene: BLi02916: NAD biosynthesis transcription regulator, HTH_11 family	Anoxybacillus flavithermus WK1 Gene: Aflv_0701: NAD biosynthesis transcription regulator, HTH_11 family	Geobacillus kaustophilus HTA426 Gene: GK2603: NAD biosynthesis transcription regulator, HTH_11 family	Bacillus cereus ATCC 14579 Gene: BC4425: NAD biosynthesis transcription regulator, HTH_11 family	Bacillus halodurans C-125 Gene: BH1216: NAD biosynthesis transcription regulator, HTH_11 family	Bacillus clausii KSM-K16 Gene: ABC1545: NAD biosynthesis transcription regulator, HTH_11 family	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	NAD biosynthesis transcription regulator, HTH_11 family

CRON 3.
nadB	* Bacillus subtilis subsp. subtilis str. 168 Site: position = -41 score = 6.48385 sequence = TATAGGTGTCAAGACAGGTGTA Gene: BSU27870: L-aspartate oxidase (EC 1.4.3.16)	* Bacillus amyloliquefaciens FZB42 Site: position = -43 score = 6.48385 sequence = TATAGGTGTCAAGACAGGTGTA Gene: RBAM_024920: L-aspartate oxidase (EC 1.4.3.16)	* Bacillus pumilus SAFR-032 Site: position = -38 score = 5.90135 sequence = GATATGTGTCAAGACAGGTGTA Gene: BPUM_2427: L-aspartate oxidase (EC 1.4.3.16)	* Bacillus licheniformis DSM 13 Site: position = -42 score = 6.6209 sequence = TATAGGTGTCAAGACACATGTA Gene: BLi02914: L-aspartate oxidase (EC 1.4.3.16)	* Anoxybacillus flavithermus WK1 Site: position = -37 score = 5.45278 sequence = TATAGGTGTCAAGACAGTATGA Site: position = -49 score = 4.38702 sequence = AATATATGTCAATATAGGTGTC Gene: Aflv_0703: L-aspartate oxidase (EC 1.4.3.16)	* Geobacillus kaustophilus HTA426 Site: position = -41 score = 6.06852 sequence = TATAGATGTCAAGACAGGTGAA Gene: GK2601: L-aspartate oxidase (EC 1.4.3.16)	* Bacillus cereus ATCC 14579 Site: position = -47 score = 6.15591 sequence = TATAGGTGTCAAGACAGTTGGA Gene: BC4423: L-aspartate oxidase (EC 1.4.3.16)	* Bacillus halodurans C-125 Site: position = -39 score = 6.44612 sequence = TATAGATGTCAAGACATATGTA Gene: BH1218: L-aspartate oxidase (EC 1.4.3.16)	* Bacillus clausii KSM-K16 Site: position = -36 score = 6.05862 sequence = TATAGGTGACAAGACAACTGTA Gene: ABC1547: L-aspartate oxidase (EC 1.4.3.16)	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_0069: L-aspartate oxidase (EC 1.4.3.16)	L-aspartate oxidase (EC 1.4.3.16)
nadC	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU27860: Probable nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_024910: Probable nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19)	Bacillus pumilus SAFR-032 Gene: BPUM_2426: Probable nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19)	Bacillus licheniformis DSM 13 Gene: BLi02913: Probable nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19)	Anoxybacillus flavithermus WK1 Gene: Aflv_0704: Probable nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19)	Geobacillus kaustophilus HTA426 Gene: GK2600: Probable nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19)	Bacillus cereus ATCC 14579 Gene: BC4422: Probable nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19)	Bacillus halodurans C-125 Gene: BH1219: Probable nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19)	Bacillus clausii KSM-K16 Gene: ABC1548: Probable nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19)	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_0070: Probable nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19)	Probable nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19)
nadA	Bacillus subtilis subsp. subtilis str. 168 Gene: BSU27850: Quinolinate synthetase (EC 4.1.99.-)	Bacillus amyloliquefaciens FZB42 Gene: RBAM_024900: Quinolinate synthetase (EC 4.1.99.-)	Bacillus pumilus SAFR-032 Gene: BPUM_2425: Quinolinate synthetase (EC 4.1.99.-)	Bacillus licheniformis DSM 13 Gene: BLi02912: Quinolinate synthetase (EC 4.1.99.-)	Anoxybacillus flavithermus WK1 Gene: Aflv_0705: Quinolinate synthetase (EC 4.1.99.-)	Geobacillus kaustophilus HTA426 Gene: GK2599: Quinolinate synthetase (EC 4.1.99.-)	Bacillus cereus ATCC 14579 Gene: BC4421: Quinolinate synthetase (EC 4.1.99.-)	Bacillus halodurans C-125 Gene: BH1220: Quinolinate synthetase (EC 4.1.99.-)	Bacillus clausii KSM-K16 Gene: ABC1549: Quinolinate synthetase (EC 4.1.99.-)	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2 Gene: Pjdr2_0068: Quinolinate synthetase (EC 4.1.99.-)	Quinolinate synthetase (EC 4.1.99.-)

CRON 4.
niaY	Bacillus subtilis subsp. subtilis str. 168	Bacillus amyloliquefaciens FZB42	Bacillus pumilus SAFR-032 Gene: BPUM_2631: Predicted nicotinate-regulated transporter NiaY	Bacillus licheniformis DSM 13	Anoxybacillus flavithermus WK1	Geobacillus kaustophilus HTA426	Bacillus cereus ATCC 14579	* Bacillus halodurans C-125 Site: position = -85 score = 5.27121 sequence = GAAATGTGTCTTGTCATGTGTA Gene: BH3254: Predicted nicotinate-regulated transporter NiaY	* Bacillus clausii KSM-K16 Site: position = -76 score = 5.03066 sequence = AAAAAGTGTCTTGTCACATGAA Gene: ABC2773: Predicted nicotinate-regulated transporter NiaY	Oceanobacillus iheyensis HTE831	Paenibacillus sp. JDR-2	Predicted nicotinate-regulated transporter NiaY

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog NiaR - Bacillales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --