Regulog LexA - Frankineae/Propionibacterineae/Pseudonocardiaceae
| Regulator type: | Transcription factor |
| Regulator family: | LexA |
| Regulation mode: | repressor |
| Biological process: | SOS response |
| Effector: | DNA damage |
| Phylum: | Actinobacteria |
| Visualization: | |
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Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By trascription factor - LexA
- By taxonomy - Frankineae/Propionibacterineae/Pseudonocardiaceae
- By TF family - LexA
- By effector - DNA damage
- By pathway - SOS response
| Genome | Genes | Operons |
|---|---|---|
| Frankia sp. CcI3 | 12 | 8 |
| Frankia sp. EAN1pec | 13 | 9 |
| Nakamurella multipartita DSM 44233 | 9 | 6 |
| Acidothermus cellulolyticus 11B | 8 | 5 |
| Nocardioides sp. JS614 | 8 | 5 |
| Propionibacterium acnes KPA171202 | 2 | 1 |
| Actinosynnema mirum DSM 43827 | 12 | 8 |
| Saccharomonospora viridis DSM 43017 | 9 | 5 |
| Saccharopolyspora erythraea NRRL 2338 | 6 | 4 |
| Genes | Function | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| CRON 1. | ||||||||||
| ruvC |
*
Frankia sp. CcI3 Site: position = -40 score = 4.52504 sequence = TCGAACGAATGTTCTT Gene: Francci3_1369: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
*
Frankia sp. EAN1pec Site: position = -37 score = 5.3571 sequence = TCGAACGGATGTTCGT Gene: Franean1_5146: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
*
Nakamurella multipartita DSM 44233 Site: position = -85 score = 4.04182 sequence = CTGGACAGGTGTTCGC Gene: Namu_3396: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
*
Acidothermus cellulolyticus 11B Site: position = 15 score = 5.52401 sequence = CCGAACATGCGTTCGA Gene: Acel_1345: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
*
Nocardioides sp. JS614 Site: position = -31 score = 5.42347 sequence = CCGAACACCTGTTCGG Gene: Noca_2385: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
Gene: PPA1158: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
*
Actinosynnema mirum DSM 43827 Site: position = -58 score = 5.00898 sequence = TCGAACTGGTGTTCGC Gene: Amir_1692: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
*
Saccharomonospora viridis DSM 43017 Site: position = -33 score = 5.00898 sequence = TCGAACTGGTGTTCGC Gene: Svir_15060: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
*
Saccharopolyspora erythraea NRRL 2338 Site: position = -37 score = 5.05181 sequence = TCGAACGCGTGTTCAG Gene: SACE_2021: Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
Crossover junction endodeoxyribonuclease RuvC (EC 3.1.22.4) |
| ruvA |
Gene: Francci3_1370: Holliday junction DNA helicase RuvA |
Gene: Franean1_5145: Holliday junction DNA helicase RuvA |
Gene: Namu_3395: Holliday junction DNA helicase RuvA |
Gene: Acel_1344: Holliday junction DNA helicase RuvA |
Gene: Noca_2386: Holliday junction DNA helicase RuvA |
Gene: PPA1159: Holliday junction DNA helicase RuvA |
Gene: Amir_1691: Holliday junction DNA helicase RuvA |
Gene: Svir_15070: Holliday junction DNA helicase RuvA |
Gene: SACE_2022: Holliday junction DNA helicase RuvA |
Holliday junction DNA helicase RuvA |
| ruvB |
Gene: Francci3_1371: Holliday junction DNA helicase RuvB |
Gene: Franean1_5144: Holliday junction DNA helicase RuvB |
Gene: Namu_3394: Holliday junction DNA helicase RuvB |
Gene: Acel_1343: Holliday junction DNA helicase RuvB |
Gene: Noca_2387: Holliday junction DNA helicase RuvB |
Gene: PPA1160: Holliday junction DNA helicase RuvB |
Gene: Amir_1690: Holliday junction DNA helicase RuvB |
Gene: Svir_15080: Holliday junction DNA helicase RuvB |
Gene: SACE_2023: Holliday junction DNA helicase RuvB |
Holliday junction DNA helicase RuvB |
| CRON 2. | ||||||||||
| lexA |
*
Frankia sp. CcI3 Site: position = -198 score = 5.38324 sequence = TCGAACAGACGTTTGA Site: position = -251 score = 5.25263 sequence = TCGAACGCGTGGTCGA Site: position = -267 score = 5.00596 sequence = TCGAACCTTCGTTCGA Gene: Francci3_3510: SOS-response repressor and protease LexA (EC 3.4.21.88) |
*
Frankia sp. EAN1pec Site: position = -298 score = 4.90907 sequence = TCGAACGCCTGAGCGA Site: position = -244 score = 5.38324 sequence = TCGAACAGACGTTTGA Gene: Franean1_1232: SOS-response repressor and protease LexA (EC 3.4.21.88) |
*
Nakamurella multipartita DSM 44233 Site: position = -202 score = 5.08489 sequence = TCGAACGGACGTTCTA Site: position = -186 score = 4.43881 sequence = TCGAACGTCTGCACGA Site: position = -123 score = 5.49247 sequence = TCGAACGGGTGTTTGA Gene: Namu_3979: SOS-response repressor and protease LexA (EC 3.4.21.88) |
*
Acidothermus cellulolyticus 11B Site: position = -106 score = 5.12966 sequence = TCGAACTGGTGTTTGA Site: position = -161 score = 5.28686 sequence = TCGAACGGGTGTACGA Site: position = -177 score = 5.89309 sequence = TCGAACACGCGTTCGA Gene: Acel_1479: SOS-response repressor and protease LexA (EC 3.4.21.88) |
*
Nocardioides sp. JS614 Site: position = -47 score = 5.57628 sequence = TCGAACAGGTGTTTGA Gene: Noca_3817: SOS-response repressor and protease LexA (EC 3.4.21.88) |
|
*2
Actinosynnema mirum DSM 43827 Site: position = -157 score = 3.75798 sequence = ACGACCTCGTGCTCGA Gene: Amir_3974: SOS-response repressor and protease LexA (EC 3.4.21.88) Site: position = -184 score = 5.575 sequence = TCGAACAACCGTTCGA Site: position = -168 score = 5.28722 sequence = TCGAACGCCCGTGCGA Site: position = -103 score = 5.57628 sequence = TCGAACAGGTGTTTGA Gene: Amir_1434: SOS-response repressor and protease LexA (EC 3.4.21.88) |
*
Saccharomonospora viridis DSM 43017 Site: position = -102 score = 5.13261 sequence = TCGAACAAACGTTTGA Site: position = -165 score = 5.37103 sequence = TCGAACACCCGTGCGA Gene: Svir_27590: SOS-response repressor and protease LexA (EC 3.4.21.88) |
*2
Saccharopolyspora erythraea NRRL 2338 Site: position = -98 score = 5.57628 sequence = TCGAACAGGTGTTTGA Site: position = -164 score = 4.80198 sequence = TCGAACCTGCGTGCGA Site: position = -180 score = 5.09884 sequence = TCGAATGGATGTTCGA Gene: SACE_1760: SOS-response repressor and protease LexA (EC 3.4.21.88) Gene: SACE_2836: SOS-response repressor and protease LexA (EC 3.4.21.88) |
SOS-response repressor and protease LexA (EC 3.4.21.88) |
| CRON 3. | ||||||||||
| recA |
*
Frankia sp. CcI3 Site: position = -139 score = 5.39083 sequence = TCGAACGCATGTTCGT Gene: Francci3_3525: Recombinase A |
*2
Frankia sp. EAN1pec Site: position = -138 score = 5.49028 sequence = TCGAACGGATGTTCGG Gene: Franean1_1219: Recombinase A Site: position = -142 score = 5.23965 sequence = TCGAACGAATGTTCGG Gene: Franean1_6708: Recombinase A |
*
Nakamurella multipartita DSM 44233 Site: position = -132 score = 4.97764 sequence = TCGAACAGGTGTACGT Site: position = -284 score = 3.92661 sequence = TCGATCAGGCGCTGGA Gene: Namu_3994: Recombinase A |
*
Acidothermus cellulolyticus 11B Site: position = -142 score = 5.57408 sequence = TCGAACATCTGTTCGG Gene: Acel_1492: Recombinase A |
*
Nocardioides sp. JS614 Site: position = -151 score = 5.68332 sequence = TCGAACAGGTGTTCGG Gene: Noca_2341: Recombinase A |
Gene: PPA1012: Recombinase A |
*
Actinosynnema mirum DSM 43827 Site: position = -151 score = 5.68332 sequence = TCGAACACCTGTTCGG Site: position = -264 score = 4.22706 sequence = CCGACCAGGCGTTGGA Gene: Amir_1419: Recombinase A |
*
Saccharomonospora viridis DSM 43017 Site: position = -168 score = 5.68332 sequence = TCGAACAGGTGTTCGG Gene: Svir_27820: Recombinase A |
*
Saccharopolyspora erythraea NRRL 2338 Site: position = -143 score = 5.46634 sequence = TCGAACACCCGTTCGT Gene: SACE_1736: Recombinase A |
Recombinase A |
| recX |
Gene: Francci3_3524: Regulatory protein RecX |
Gene: Franean1_1220: Regulatory protein RecX |
Gene: Namu_3993: Regulatory protein RecX |
Gene: Acel_1491: Regulatory protein RecX |
Gene: Noca_2342: Regulatory protein RecX |
Gene: PPA1013: Regulatory protein RecX |
Gene: Amir_1420: Regulatory protein RecX |
Gene: Svir_27810: Regulatory protein RecX |
Gene: SACE_1737: Regulatory protein RecX |
Regulatory protein RecX |
| CRON 4. | ||||||||||
| uvrA |
Gene: Francci3_1631: Excinuclease ABC, subunit A |
*
Frankia sp. EAN1pec Site: position = -227 score = 5.44239 sequence = TCGAACGCGCGTTTGA Gene: Franean1_2057: Excinuclease ABC, subunit A |
Gene: Namu_2992: Excinuclease ABC, subunit A |
Gene: Acel_1109: Excinuclease ABC, subunit A |
*
Nocardioides sp. JS614 Site: position = -42 score = 5.55014 sequence = ACGAACACCTGTTCGA Gene: Noca_2524: Excinuclease ABC, subunit A |
Gene: PPA0807: Excinuclease ABC, subunit A |
*
Actinosynnema mirum DSM 43827 Site: position = -38 score = 5.60781 sequence = TCGAACATGTGTTCGG Gene: Amir_5483: Excinuclease ABC, subunit A |
Gene: Svir_25750: Excinuclease ABC, subunit A |
Gene: SACE_5314: Excinuclease ABC, subunit A |
Excinuclease ABC, subunit A |
| CRON 5. | ||||||||||
| PF02720 |
*
Frankia sp. CcI3 Site: position = -197 score = 4.96735 sequence = CCGAACACATGGTCGA Site: position = 28 score = 5.60781 sequence = TCGAACACATGTTCGG Gene: Francci3_0067: HNH endonuclease |
*2
Frankia sp. EAN1pec Gene: Franean1_4861: HNH endonuclease Site: position = -75 score = 3.72378 sequence = CCGTTCGGGTGTTCTG Gene: Franean1_3452: HNH endonuclease |
*
Nakamurella multipartita DSM 44233 Site: position = -49 score = 3.95802 sequence = GTGGACACCCGTTCGG Gene: Namu_3157: HNH endonuclease |
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HNH endonuclease |
| CRON 6. | ||||||||||
| dnaB |
*
Frankia sp. CcI3 Site: position = -50 score = 5.28159 sequence = ACGAACATACGTTCGA Gene: Francci3_4518: Replicative DNA helicase (EC 3.6.1.-) |
*
Frankia sp. EAN1pec Site: position = -137 score = 5.75842 sequence = TCGAACATATGTTCGA Gene: Franean1_7308: Replicative DNA helicase (EC 3.6.1.-) |
*
Nakamurella multipartita DSM 44233 Site: position = -98 score = 4.45388 sequence = CAGAACACATGTCCGA Gene: Namu_5363: Replicative DNA helicase (EC 3.6.1.-) |
Gene: Acel_2083: Replicative DNA helicase (EC 3.6.1.-) |
Gene: Noca_4657: Replicative DNA helicase (EC 3.6.1.-) |
Gene: PPA2244: Replicative DNA helicase (EC 3.6.1.-) |
Gene: Amir_7043: Replicative DNA helicase (EC 3.6.1.-) |
*
Saccharomonospora viridis DSM 43017 Site: position = -44 score = 5.85936 sequence = TCGAACAGGCGTTCGA Gene: Svir_39470: Replicative DNA helicase (EC 3.6.1.-) |
Gene: SACE_7347: Replicative DNA helicase (EC 3.6.1.-) |
Replicative DNA helicase (EC 3.6.1.-) |
| CRON 7. | ||||||||||
| dprA |
*
Frankia sp. CcI3 Site: position = -268 score = 4.12562 sequence = CCGAGCGGGCATTCGA Gene: Francci3_3584: DNA protecting protein DprA |
*
Frankia sp. EAN1pec Site: position = -154 score = 4.05011 sequence = CCGACCGTGCCTTCGA Gene: Franean1_1158: DNA protecting protein DprA |
Gene: Namu_3121: DNA protecting protein DprA |
*
Acidothermus cellulolyticus 11B Site: position = -46 score = 4.27636 sequence = GCGAACACGTGGACGA Site: position = -151 score = 4.32766 sequence = TCGAACGCGCCTTGGA Gene: Acel_1548: DNA protecting protein DprA |
Gene: Noca_3246: DNA protecting protein DprA |
Gene: PPA1429: DNA protecting protein DprA |
*
Actinosynnema mirum DSM 43827 Site: position = -26 score = 5.75013 sequence = TCGAACAGACGTTCGA Site: position = -87 score = 4.18541 sequence = TCGACCACCCGGTCGT Gene: Amir_5585: DNA protecting protein DprA |
Gene: Svir_09850: DNA protecting protein DprA |
Gene: SACE_6043: DNA protecting protein DprA |
DNA protecting protein DprA |
| xerC |
Gene: Francci3_3583: Site-specific DNA-tyrosine recombinase, XerC |
Gene: Franean1_1159: Site-specific DNA-tyrosine recombinase, XerC |
Gene: Namu_3115: Site-specific DNA-tyrosine recombinase, XerC |
Gene: Acel_1547: Site-specific DNA-tyrosine recombinase, XerC |
Gene: Noca_3245: Site-specific DNA-tyrosine recombinase, XerC |
Gene: PPA1522: Site-specific DNA-tyrosine recombinase, XerC |
Gene: Amir_5914: Site-specific DNA-tyrosine recombinase, XerC |
Gene: Svir_09860: Site-specific DNA-tyrosine recombinase, XerC |
Gene: SACE_6041: Site-specific DNA-tyrosine recombinase, XerC |
Site-specific DNA-tyrosine recombinase, XerC |
| CRON 8. | ||||||||||
| PPA1757 |
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*
Propionibacterium acnes KPA171202 Site: position = -83 score = 3.97338 sequence = TCGATCGTGGGATCGT Gene: PPA1757: Hypothetical protein |
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Hypothetical protein |
| uvrD |
*
Frankia sp. CcI3 Site: position = -22 score = 4.86901 sequence = TCGAACGTACGATCGG Gene: Francci3_0647: ATP-dependent DNA helicase II |
*
Frankia sp. EAN1pec Site: position = -22 score = 5.12886 sequence = TCGAACGTACGATCGA Gene: Franean1_5987: ATP-dependent DNA helicase II |
*
Nakamurella multipartita DSM 44233 Site: position = -77 score = 5.22136 sequence = CCGAACAGGTGATCGA Gene: Namu_1258: ATP-dependent DNA helicase II |
*
Acidothermus cellulolyticus 11B Site: position = 29 score = 3.6491 sequence = CCGGCCACGTGATCGT Gene: Acel_0375: ATP-dependent DNA helicase II |
*
Nocardioides sp. JS614 Site: position = -289 score = 4.29323 sequence = CCGACAACCTGTTCGA Gene: Noca_3593: ATP-dependent DNA helicase II |
Gene: PPA1756: ATP-dependent DNA helicase II |
Gene: Amir_6513: ATP-dependent DNA helicase II |
Gene: Svir_04890: ATP-dependent DNA helicase II |
Gene: SACE_6681: ATP-dependent DNA helicase II |
ATP-dependent DNA helicase II |
| CRON 9. | ||||||||||
| gyrB |
Gene: Francci3_1761: Topoisomerase IV, subunit B (EC 5.99.1.-) |
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Gene: Acel_1427: Topoisomerase IV, subunit B (EC 5.99.1.-) |
Gene: Noca_2958: Topoisomerase IV, subunit B (EC 5.99.1.-) |
Gene: PPA1042: Topoisomerase IV, subunit B (EC 5.99.1.-) |
*
Actinosynnema mirum DSM 43827 Site: position = -100 score = 5.5262 sequence = TCGAACGCGTGTTTGA Gene: Amir_2280: Topoisomerase IV, subunit B (EC 5.99.1.-) |
*
Saccharomonospora viridis DSM 43017 Site: position = -24 score = 4.62435 sequence = TCGAACAGTTGACCGA Gene: Svir_08220: Topoisomerase IV, subunit B (EC 5.99.1.-) |
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Topoisomerase IV, subunit B (EC 5.99.1.-) |
| gyrA |
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Gene: Acel_1422: Topoisomerase IV, subunit A (EC 5.99.1.-) |
Gene: Noca_2949: Topoisomerase IV, subunit A (EC 5.99.1.-) |
Gene: PPA1045: Topoisomerase IV, subunit A (EC 5.99.1.-) |
Gene: Amir_2281: Topoisomerase IV, subunit A (EC 5.99.1.-) |
Gene: Svir_08230: Topoisomerase IV, subunit A (EC 5.99.1.-) |
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Topoisomerase IV, subunit A (EC 5.99.1.-) |
| CRON 10. | ||||||||||
| hsdR |
*
Frankia sp. CcI3 Site: position = -233 score = 3.73751 sequence = GAGAACGGCAGTACGA Gene: Francci3_0194: Type I restriction-modification system, restriction subunit R (EC 3.1.21.3) |
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*
Actinosynnema mirum DSM 43827 Site: position = 16 score = 4.09539 sequence = ACGAATCCGCGTTCGG Gene: Amir_0958: Type I restriction-modification system, restriction subunit R (EC 3.1.21.3) |
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*
Saccharopolyspora erythraea NRRL 2338 Site: position = -177 score = 4.08266 sequence = AGGAACAGGCGGTCGA Gene: SACE_0868: Type I restriction-modification system, restriction subunit R (EC 3.1.21.3) |
Type I restriction-modification system, restriction subunit R (EC 3.1.21.3) |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |