Statistics of regulated genes

Genome	Genes	Operons
Azoarcus sp. EbN1	10	5
Thauera sp. MZ1T	12	6
Dechloromonas aromatica RCB	12	5
Nitrosomonas europaea ATCC 19718
Nitrosospira multiformis ATCC 25196
Thiobacillus denitrificans	8	3
Chromobacterium violaceum ATCC 12472	6	3
Neisseria meningitidis MC58
Laribacter hongkongensis HLHK9	1	1
Methylobacillus flagellatus KT	6	2
Methylotenera mobilis JLW8	13	5
Methylophilales bacterium HTCC2181	7	3

Clusters of co-Regulated Orthologous operoNs (CRONs)

Genes													Function
CRON 1.
glnA	* Azoarcus sp. EbN1 Site: position = -253 score = 5.54432 sequence = TGCACCATGATGGTGCG Gene: ebA4121: Glutamine synthetase type I (EC 6.3.1.2)	* Thauera sp. MZ1T Site: position = -196 score = 5.14676 sequence = CGCACCATTGAAGTGCA Site: position = -228 score = 5.4965 sequence = CGCACCATAGTAGTGCA Gene: Tmz1t_3648: Glutamine synthetase type I (EC 6.3.1.2)	* Dechloromonas aromatica RCB Site: position = -214 score = 5.66532 sequence = TGCACCAAAATAGTGCG Site: position = -183 score = 5.0109 sequence = TGCACGATCGTGGTGCA Gene: Daro_3763: Glutamine synthetase type I (EC 6.3.1.2)	Nitrosomonas europaea ATCC 19718 Gene: NE0504: Glutamine synthetase type I (EC 6.3.1.2)	Nitrosospira multiformis ATCC 25196 Gene: Nmul_A2288: Glutamine synthetase type I (EC 6.3.1.2)	* Thiobacillus denitrificans Site: position = -188 score = 4.33197 sequence = CGCCCTATAATGGAGCG Site: position = -220 score = 4.97217 sequence = TGCACCAAGACGGGGCA Gene: Tbd_2503: Glutamine synthetase type I (EC 6.3.1.2)	* Chromobacterium violaceum ATCC 12472 Site: position = -202 score = 5.22356 sequence = GGCACCATATCGGTGCA Site: position = -172 score = 4.6826 sequence = GGCACCAGAATGGTTCA Gene: CV3589: Glutamine synthetase type I (EC 6.3.1.2)	Neisseria meningitidis MC58 Gene: NMB0359: Glutamine synthetase type I (EC 6.3.1.2)	* Laribacter hongkongensis HLHK9 Site: position = -226 score = 5.44086 sequence = TTCACCATTTTGGTGCA Site: position = -255 score = 5.11526 sequence = TGCACCATTGATGTGCA Gene: LHK_01876: Glutamine synthetase type I (EC 6.3.1.2)	* Methylobacillus flagellatus KT Site: position = -189 score = 5.57169 sequence = AGCACCAATATGGTGCA Site: position = -158 score = 4.90293 sequence = CGCAATATAGTGGTGCA Gene: Mfla_2447: Glutamine synthetase type I (EC 6.3.1.2)	* Methylotenera mobilis JLW8 Site: position = -153 score = 4.99457 sequence = TGCATTGTATTGGTGCA Site: position = -183 score = 5.28408 sequence = TGCACCAAAAATGTGCA Gene: Mmol_2138: Glutamine synthetase type I (EC 6.3.1.2)	* Methylophilales bacterium HTCC2181 Site: position = -173 score = 5.45712 sequence = TGCACTAAATTAGTGCG Site: position = -141 score = 4.42018 sequence = AGCATTTAATTGGTGCA Gene: MB2181_01610: Glutamine synthetase type I (EC 6.3.1.2)	Glutamine synthetase type I (EC 6.3.1.2)
ntrZ	Azoarcus sp. EbN1 Gene: ebA4118: Conserved hypothetical signal peptide protein	Thauera sp. MZ1T Gene: Tmz1t_3649: Conserved hypothetical signal peptide protein	Dechloromonas aromatica RCB Gene: Daro_3762: Conserved hypothetical signal peptide protein	Nitrosomonas europaea ATCC 19718 Gene: NE0503: Conserved hypothetical signal peptide protein	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans Gene: Tbd_2502: Conserved hypothetical signal peptide protein	Chromobacterium violaceum ATCC 12472 Gene: CV3590: Conserved hypothetical signal peptide protein	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9	Methylobacillus flagellatus KT Gene: Mfla_2448: Conserved hypothetical signal peptide protein	Methylotenera mobilis JLW8 Gene: Mmol_2139: Conserved hypothetical signal peptide protein	Methylophilales bacterium HTCC2181	Conserved hypothetical signal peptide protein
ntrB	Azoarcus sp. EbN1 Gene: ebA4117: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Thauera sp. MZ1T Gene: Tmz1t_3650: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	* Dechloromonas aromatica RCB Site: position = -204 score = 5.56447 sequence = TGCACCAATACGGTGCG Gene: Daro_3759: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans Gene: Tbd_2501: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	* Chromobacterium violaceum ATCC 12472 Site: position = -118 score = 6.03802 sequence = TGCACCAAAATGGTGCA Gene: CV3591: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9 Gene: LHK_01905: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Methylobacillus flagellatus KT Gene: Mfla_2449: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	* Methylotenera mobilis JLW8 Site: position = -268 score = 5.68828 sequence = TGCACCTAAATGGTGCA Site: position = -9 score = 4.91006 sequence = AGCACTATTATGGTTCA Gene: Mmol_2140: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Methylophilales bacterium HTCC2181 Gene: MB2181_01605: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Nitrogen regulation protein NR(II) (EC 2.7.3.-)
ntrC	* Azoarcus sp. EbN1 Site: position = -23 score = 5.31558 sequence = CGCACCAAAAAAGTGCA Gene: ebA4116: Nitrogen regulation protein NR(I), Fis family	* Thauera sp. MZ1T Site: position = -23 score = 5.3698 sequence = CGCACCAGAATAGTGCA Gene: Tmz1t_3651: Nitrogen regulation protein NR(I), Fis family	Dechloromonas aromatica RCB Gene: Daro_3758: Nitrogen regulation protein NR(I), Fis family	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans Gene: Tbd_2500: Nitrogen regulation protein NR(I), Fis family	Chromobacterium violaceum ATCC 12472 Gene: CV3592: Nitrogen regulation protein NR(I), Fis family	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9 Gene: LHK_01906: Nitrogen regulation protein NR(I), Fis family	Methylobacillus flagellatus KT Gene: Mfla_2450: Nitrogen regulation protein NR(I), Fis family	Methylotenera mobilis JLW8 Gene: Mmol_2141: Nitrogen regulation protein NR(I), Fis family	Methylophilales bacterium HTCC2181 Gene: MB2181_01600: Nitrogen regulation protein NR(I), Fis family	Nitrogen regulation protein NR(I), Fis family
CRON 2.
CHP02001	* Azoarcus sp. EbN1 Site: position = 20 score = 4.99359 sequence = CGCACCGTTCCGGTGCA Gene: ebA3154: Conserved hypothetical protein CHP02001	* Thauera sp. MZ1T Site: position = -175 score = 5.43914 sequence = CGCACCACATTGGTGCG Gene: Tmz1t_0595: Conserved hypothetical protein CHP02001	* Dechloromonas aromatica RCB Site: position = -148 score = 4.96208 sequence = CGCACAGTTTTGGTGCG Gene: Daro_0052: Conserved hypothetical protein CHP02001	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans Gene: Tbd_0239: Conserved hypothetical protein CHP02001	Chromobacterium violaceum ATCC 12472	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9	Methylobacillus flagellatus KT Gene: Mfla_2512: Conserved hypothetical protein CHP02001	* Methylotenera mobilis JLW8 Site: position = -288 score = 4.71349 sequence = CGCCCTTTAATAGTGCA Gene: Mmol_2289: Conserved hypothetical protein CHP02001	* Methylophilales bacterium HTCC2181 Site: position = -282 score = 4.74984 sequence = TGCCCTGAAGTAGTGCA Gene: MB2181_01245: Conserved hypothetical protein CHP02001	Conserved hypothetical protein CHP02001
glnK	Azoarcus sp. EbN1 Gene: ebB95: Nitrogen regulatory protein P-II	Thauera sp. MZ1T Gene: Tmz1t_0594: Nitrogen regulatory protein P-II	Dechloromonas aromatica RCB Gene: Daro_0053: Nitrogen regulatory protein P-II	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans Gene: Tbd_0240: Nitrogen regulatory protein P-II	* Chromobacterium violaceum ATCC 12472 Site: position = -176 score = 5.23357 sequence = TGCACCAAAACCGTGCA Gene: CV4002: Nitrogen regulatory protein P-II	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9	*2 Methylobacillus flagellatus KT Site: position = -188 score = 5.3427 sequence = TGAACTATTTTGGTGCA Site: position = -206 score = 5.08157 sequence = TGCACATCATTGGTGCA Gene: Mfla_0433: Nitrogen regulatory protein P-II Gene: Mfla_2513: Nitrogen regulatory protein P-II	Methylotenera mobilis JLW8 Gene: Mmol_2290: Nitrogen regulatory protein P-II	Methylophilales bacterium HTCC2181 Gene: MB2181_01250: Nitrogen regulatory protein P-II	Nitrogen regulatory protein P-II
amtB	Azoarcus sp. EbN1 Gene: ebA3151: Ammonium transporter	Thauera sp. MZ1T Gene: Tmz1t_0593: Ammonium transporter	Dechloromonas aromatica RCB Gene: Daro_0054: Ammonium transporter	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans Gene: Tbd_0241: Ammonium transporter	Chromobacterium violaceum ATCC 12472 Gene: CV4003: Ammonium transporter	Neisseria meningitidis MC58 Gene: NMB0615: Ammonium transporter	Laribacter hongkongensis HLHK9 Gene: LHK_02933: Ammonium transporter	2 Methylobacillus flagellatus KT Gene: Mfla_2514: Ammonium transporter Gene: Mfla_0434: Ammonium transporter	Methylotenera mobilis JLW8 Gene: Mmol_2291: Ammonium transporter	Methylophilales bacterium HTCC2181 Gene: MB2181_01255: Ammonium transporter	Ammonium transporter
CRON 3.
amtB2	* Azoarcus sp. EbN1 Site: position = -159 score = 5.19396 sequence = CGCACCGTAATTGTGCA Gene: ebA4609: Ammonium transporter	* Thauera sp. MZ1T Site: position = -115 score = 4.47361 sequence = CGCACCCCTCTGGTGCG Site: position = -49 score = 4.35274 sequence = CGCACTGGAACGGTGCT Gene: Tmz1t_0457: Ammonium transporter	* Dechloromonas aromatica RCB Site: position = -119 score = 4.89274 sequence = TGCACCAAACAGGTGCT Site: position = -53 score = 4.82629 sequence = TGCACTGGAATGGTGCT Gene: Daro_3703: Ammonium transporter	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	* Thiobacillus denitrificans Site: position = -114 score = 4.33968 sequence = CGCACTTCGGCGGTGCA Gene: Tbd_1701: Ammonium transporter	Chromobacterium violaceum ATCC 12472	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9 Gene: LHK_03154: Ammonium transporter	Methylobacillus flagellatus KT	* Methylotenera mobilis JLW8 Site: position = -152 score = 5.07588 sequence = TGCACATATTTAGTGCA Site: position = -122 score = 5.1301 sequence = TGCACAATGTTAGTGCA Gene: Mmol_1494: Ammonium transporter	* Methylophilales bacterium HTCC2181 Site: position = -134 score = 5.26994 sequence = TGCACCAAAATAATGCA Gene: MB2181_03520: Ammonium transporter	Ammonium transporter
CRON 4.
gltB	* Azoarcus sp. EbN1 Site: position = -96 score = 5.16027 sequence = TGCACAGTTTTGGTGCG Gene: ebA2252: Glutamate synthase, large chain (EC 1.4.1.13)	* Thauera sp. MZ1T Site: position = -141 score = 5.70881 sequence = TGCACCAGATTGGTGCA Gene: Tmz1t_0842: Glutamate synthase, large chain (EC 1.4.1.13)	Dechloromonas aromatica RCB Gene: Daro_0217: Glutamate synthase, large chain (EC 1.4.1.13)	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	Chromobacterium violaceum ATCC 12472	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9	Methylobacillus flagellatus KT	Methylotenera mobilis JLW8 Gene: Mmol_2309: Glutamate synthase, large chain (EC 1.4.1.13)	Methylophilales bacterium HTCC2181 Gene: MB2181_01170: Glutamate synthase, large chain (EC 1.4.1.13)	Glutamate synthase, large chain (EC 1.4.1.13)
gltD	Azoarcus sp. EbN1 Gene: ebA2251: Glutamate synthase, small chain (EC 1.4.1.13)	Thauera sp. MZ1T Gene: Tmz1t_0843: Glutamate synthase, small chain (EC 1.4.1.13)	Dechloromonas aromatica RCB Gene: Daro_0218: Glutamate synthase, small chain (EC 1.4.1.13)	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	Chromobacterium violaceum ATCC 12472	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9	Methylobacillus flagellatus KT	Methylotenera mobilis JLW8 Gene: Mmol_2308: Glutamate synthase, small chain (EC 1.4.1.13)	Methylophilales bacterium HTCC2181 Gene: MB2181_01175: Glutamate synthase, small chain (EC 1.4.1.13)	Glutamate synthase, small chain (EC 1.4.1.13)
CRON 5.
nasD	Azoarcus sp. EbN1 Gene: ebA1216: Nitrite reductase, large subunit (EC 1.7.1.4)	* Thauera sp. MZ1T Site: position = -290 score = 4.33303 sequence = CGCACCAGGGCTGTGCA Site: position = -258 score = 4.74326 sequence = TGCACCGCAGCAGTGCG Gene: Tmz1t_1142: Nitrite reductase, large subunit (EC 1.7.1.4)	* Dechloromonas aromatica RCB Site: position = -199 score = 5.27706 sequence = TGCACGAATTTGGTGCG Gene: Daro_0816: Nitrite reductase, large subunit (EC 1.7.1.4)	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans Gene: Tbd_2309: Nitrite reductase, large subunit (EC 1.7.1.4)	Chromobacterium violaceum ATCC 12472	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9	Methylobacillus flagellatus KT	* Methylotenera mobilis JLW8 Site: position = -219 score = 4.34884 sequence = TGCACCAAAGTAGTAAA Gene: Mmol_1652: Nitrite reductase, large subunit (EC 1.7.1.4)	Methylophilales bacterium HTCC2181	Nitrite reductase, large subunit (EC 1.7.1.4)
narK	Azoarcus sp. EbN1 Gene: ebA1213: Nitrate/nitrite transporter	Thauera sp. MZ1T	Dechloromonas aromatica RCB	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	Chromobacterium violaceum ATCC 12472	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9	Methylobacillus flagellatus KT	Methylotenera mobilis JLW8 Gene: Mmol_1651: Nitrate/nitrite transporter	Methylophilales bacterium HTCC2181	Nitrate/nitrite transporter
pkn	Azoarcus sp. EbN1 Gene: ebA1212: Probable serine/threonine-protein kinase SCO3848	Thauera sp. MZ1T	Dechloromonas aromatica RCB	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	Chromobacterium violaceum ATCC 12472	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9	Methylobacillus flagellatus KT	Methylotenera mobilis JLW8 Gene: Mmol_1650: Probable serine/threonine-protein kinase SCO3848	Methylophilales bacterium HTCC2181	Probable serine/threonine-protein kinase SCO3848
nasE	Azoarcus sp. EbN1 Gene: ebA1215: Nitrite reductase, small subunit (EC 1.7.1.4)	Thauera sp. MZ1T Gene: Tmz1t_1143: Nitrite reductase, small subunit (EC 1.7.1.4)	Dechloromonas aromatica RCB Gene: Daro_0817: Nitrite reductase, small subunit (EC 1.7.1.4)	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans Gene: Tbd_2308: Nitrite reductase, small subunit (EC 1.7.1.4)	Chromobacterium violaceum ATCC 12472	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9	Methylobacillus flagellatus KT	Methylotenera mobilis JLW8 Gene: Mmol_1649: Nitrite reductase, small subunit (EC 1.7.1.4)	Methylophilales bacterium HTCC2181	Nitrite reductase, small subunit (EC 1.7.1.4)
nasA	Azoarcus sp. EbN1 Gene: ebA1211: Assimilatory nitrate reductase, large subunit (EC:1.7.99.4)	Thauera sp. MZ1T	Dechloromonas aromatica RCB	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	* Thiobacillus denitrificans Site: position = -138 score = 4.4317 sequence = CGCACCAATTTGCGGCG Gene: Tbd_2310: Assimilatory nitrate reductase, large subunit (EC:1.7.99.4)	Chromobacterium violaceum ATCC 12472	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9	Methylobacillus flagellatus KT	Methylotenera mobilis JLW8 Gene: Mmol_1648: Assimilatory nitrate reductase, large subunit (EC:1.7.99.4)	Methylophilales bacterium HTCC2181	Assimilatory nitrate reductase, large subunit (EC:1.7.99.4)
Daro_0818	Azoarcus sp. EbN1	Thauera sp. MZ1T	Dechloromonas aromatica RCB Gene: Daro_0818: Hypothetical protein	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	Chromobacterium violaceum ATCC 12472	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9	Methylobacillus flagellatus KT	Methylotenera mobilis JLW8	Methylophilales bacterium HTCC2181	Hypothetical protein
narK	Azoarcus sp. EbN1	Thauera sp. MZ1T	Dechloromonas aromatica RCB Gene: Daro_0819: Nitrate/nitrite antiporter	Nitrosomonas europaea ATCC 19718 Gene: NE0680: Nitrate/nitrite antiporter	Nitrosospira multiformis ATCC 25196 Gene: Nmul_A2663: Nitrate/nitrite antiporter	Thiobacillus denitrificans Gene: Tbd_1943: Nitrate/nitrite antiporter	Chromobacterium violaceum ATCC 12472	Neisseria meningitidis MC58	Laribacter hongkongensis HLHK9	Methylobacillus flagellatus KT Gene: Mfla_0331: Nitrate/nitrite antiporter	Methylotenera mobilis JLW8	Methylophilales bacterium HTCC2181	Nitrate/nitrite antiporter

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