Regulog NtrC - Ralstonia

Properties
Regulator type:	Transcription factor
Regulator family:	Fis
Regulation mode:	activator (repressor)
Biological process:	Nitrogen assimilation
Effector:	Phosphorylated NtrB, signal histidine kinase
Phylum:	Proteobacteria/beta
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 28 sites [see more]

Member of regulog collections

By taxonomy - Ralstonia
By trascription factor - NtrC
By TF family - Fis
By effector - Phosphorylated NtrB, signal histidine kinase
By pathway - Nitrogen assimilation

Statistics of regulated genes
Genome	Genes	Operons
Ralstonia solanacearum GMI1000	14	3
Ralstonia pickettii 12J	10	3
Ralstonia metallidurans CH34	15	5
Ralstonia eutropha JMP134	15	5
Ralstonia eutropha H16	10	4
Cupriavidus taiwanensis	10	4

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes							Function

CRON 1.
glnA	2 Ralstonia solanacearum GMI1000* Site: position = -334 score = 5.1269 sequence = CGCACTATGATGGTGCG Gene: RSc1258: Glutamine synthetase type I (EC 6.3.1.2) Gene: RSp0886: Glutamine synthetase type I (EC 6.3.1.2)	* Ralstonia pickettii 12J Site: position = -346 score = 4.6835 sequence = TGCACCGTTTATGTGCG Gene: Rpic_1086: Glutamine synthetase type I (EC 6.3.1.2)	* Ralstonia metallidurans CH34 Site: position = -297 score = 4.89463 sequence = CGCACCGTTATGGTGTT Gene: Rmet_2062: Glutamine synthetase type I (EC 6.3.1.2)	* Ralstonia eutropha JMP134 Site: position = -319 score = 4.89463 sequence = CGCACCGTTATGGTGTT Gene: Reut_A2057: Glutamine synthetase type I (EC 6.3.1.2)	2 Ralstonia eutropha H16* Gene: H16_B0618: Glutamine synthetase type I (EC 6.3.1.2) Site: position = -295 score = 4.68597 sequence = TGCACCATTGTGGTGTT Gene: H16_A2335: Glutamine synthetase type I (EC 6.3.1.2)	* Cupriavidus taiwanensis Site: position = -334 score = 4.804 sequence = CGCACTAATGCGGTGCG Site: position = -304 score = 4.71001 sequence = TGCACCATGATGGTGTT Gene: RALTA_A1880: Glutamine synthetase type I (EC 6.3.1.2)	Glutamine synthetase type I (EC 6.3.1.2)
ntrZ	Ralstonia solanacearum GMI1000 Gene: RS02776: Conserved hypothetical signal peptide protein	Ralstonia pickettii 12J Gene: Rpic_1087: Conserved hypothetical signal peptide protein	* Ralstonia metallidurans CH34 Site: position = -193 score = 4.3847 sequence = TGCACCAGGAAGGGGCG Gene: Rmet_2061: Conserved hypothetical signal peptide protein	* Ralstonia eutropha JMP134 Site: position = -80 score = 4.6073 sequence = AGCACCATCAAGGGGCG Gene: Reut_A2056: Conserved hypothetical signal peptide protein	* Ralstonia eutropha H16 Site: position = -95 score = 4.66625 sequence = TGCACCAGAAAGGGGCG Gene: H16_A2334: Conserved hypothetical signal peptide protein	* Cupriavidus taiwanensis Site: position = -190 score = 4.46856 sequence = TGCACCACAAGGGGGCG Gene: RALTA_A1879: Conserved hypothetical signal peptide protein	Conserved hypothetical signal peptide protein
ntrB	Ralstonia solanacearum GMI1000 Gene: RSc1260: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Ralstonia pickettii 12J Gene: Rpic_1088: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Ralstonia metallidurans CH34 Gene: Rmet_2060: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Ralstonia eutropha JMP134 Gene: Reut_A2055: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Ralstonia eutropha H16 Gene: H16_A2333: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Cupriavidus taiwanensis Gene: RALTA_A1878: Nitrogen regulation protein NR(II) (EC 2.7.3.-)	Nitrogen regulation protein NR(II) (EC 2.7.3.-)
ntrC	Ralstonia solanacearum GMI1000 Gene: RSc1261: Nitrogen regulation protein NR(I), Fis family	Ralstonia pickettii 12J Gene: Rpic_1089: Nitrogen regulation protein NR(I), Fis family	Ralstonia metallidurans CH34 Gene: Rmet_2059: Nitrogen regulation protein NR(I), Fis family	Ralstonia eutropha JMP134 Gene: Reut_A2054: Nitrogen regulation protein NR(I), Fis family	Ralstonia eutropha H16 Gene: H16_A2332: Nitrogen regulation protein NR(I), Fis family	Cupriavidus taiwanensis Gene: RALTA_A1877: Nitrogen regulation protein NR(I), Fis family	Nitrogen regulation protein NR(I), Fis family

CRON 2.
amtB	Ralstonia solanacearum GMI1000	* Ralstonia pickettii 12J Site: position = -137 score = 4.87956 sequence = CGCACGACCATGGTGCG Gene: Rpic_0087: Ammonium transporter	* Ralstonia metallidurans CH34 Site: position = -185 score = 4.51151 sequence = TGCGCCATCACGGCGCA Gene: Rmet_4750: Ammonium transporter	* Ralstonia eutropha JMP134 Site: position = -91 score = 4.61348 sequence = TCCACCATGAAGGTGCA Site: position = -232 score = 4.65733 sequence = TGCACCACTAAGGTTCA Gene: Reut_B4038: Ammonium transporter	* Ralstonia eutropha H16 Site: position = -188 score = 4.93537 sequence = CGCGCCATTTTGGCGCA Site: position = -221 score = 5.12771 sequence = CGCACCATAACGGTTCA Gene: H16_B1234: Ammonium transporter	* Cupriavidus taiwanensis Site: position = -187 score = 4.93537 sequence = CGCGCCATTTTGGCGCA Gene: RALTA_B1139: Ammonium transporter	Ammonium transporter

CRON 3.
narK	* Ralstonia solanacearum GMI1000 Site: position = -258 score = 4.82358 sequence = TGCACCGAAACCGTGCA Gene: RS03167: Nitrate/nitrite antiporter	* Ralstonia pickettii 12J Site: position = -272 score = 4.4036 sequence = TGCACCGAAAGCGTGCG Gene: Rpic_4163: Nitrate/nitrite antiporter	* Ralstonia metallidurans CH34 Site: position = -284 score = 4.98174 sequence = CGCACCATTGCCGTGCG Gene: Rmet_4817: Nitrate/nitrite antiporter	* Ralstonia eutropha JMP134 Site: position = -271 score = 4.19835 sequence = CGCACCATGACTGTGCC Gene: Reut_B4859: Nitrate/nitrite antiporter	Ralstonia eutropha H16 Gene: H16_B0780: Nitrate/nitrite antiporter	Cupriavidus taiwanensis Gene: RALTA_B0614: Nitrate/nitrite antiporter	Nitrate/nitrite antiporter
nasD	Ralstonia solanacearum GMI1000 Gene: RSp1222: Nitrite reductase, large subunit (EC 1.7.1.4)	Ralstonia pickettii 12J Gene: Rpic_4164: Nitrite reductase, large subunit (EC 1.7.1.4)	Ralstonia metallidurans CH34 Gene: Rmet_4818: Nitrite reductase, large subunit (EC 1.7.1.4)	Ralstonia eutropha JMP134 Gene: Reut_B4860: Nitrite reductase, large subunit (EC 1.7.1.4)	Ralstonia eutropha H16 Gene: H16_B0779: Nitrite reductase, large subunit (EC 1.7.1.4)	Cupriavidus taiwanensis Gene: RALTA_B0613: Nitrite reductase, large subunit (EC 1.7.1.4)	Nitrite reductase, large subunit (EC 1.7.1.4)
nasE	Ralstonia solanacearum GMI1000 Gene: RSp1221: Nitrite reductase, small subunit (EC 1.7.1.4)	Ralstonia pickettii 12J Gene: Rpic_4165: Nitrite reductase, small subunit (EC 1.7.1.4)	Ralstonia metallidurans CH34 Gene: Rmet_4819: Nitrite reductase, small subunit (EC 1.7.1.4)	Ralstonia eutropha JMP134 Gene: Reut_B4861: Nitrite reductase, small subunit (EC 1.7.1.4)	Ralstonia eutropha H16 Gene: H16_B0778: Nitrite reductase, small subunit (EC 1.7.1.4)	Cupriavidus taiwanensis Gene: RALTA_B0612: Nitrite reductase, small subunit (EC 1.7.1.4)	Nitrite reductase, small subunit (EC 1.7.1.4)
nasB	Ralstonia solanacearum GMI1000 Gene: RS03164: Assimilatory nitrate reductase, small subunit (EC:1.7.99.4)	Ralstonia pickettii 12J Gene: Rpic_4166: Assimilatory nitrate reductase, small subunit (EC:1.7.99.4)	Ralstonia metallidurans CH34 Gene: Rmet_4820: Assimilatory nitrate reductase, small subunit (EC:1.7.99.4)	Ralstonia eutropha JMP134 Gene: Reut_B4862: Assimilatory nitrate reductase, small subunit (EC:1.7.99.4)	Ralstonia eutropha H16 Gene: H16_B0777: Assimilatory nitrate reductase, small subunit (EC:1.7.99.4)	Cupriavidus taiwanensis Gene: RALTA_B0611: Assimilatory nitrate reductase, small subunit (EC:1.7.99.4)	Assimilatory nitrate reductase, small subunit (EC:1.7.99.4)
nasA	Ralstonia solanacearum GMI1000 Gene: RSp1219: Assimilatory nitrate reductase, large subunit (EC:1.7.99.4)	Ralstonia pickettii 12J Gene: Rpic_4167: Assimilatory nitrate reductase, large subunit (EC:1.7.99.4)	Ralstonia metallidurans CH34 Gene: Rmet_4821: Assimilatory nitrate reductase, large subunit (EC:1.7.99.4)	Ralstonia eutropha JMP134 Gene: Reut_B4863: Assimilatory nitrate reductase, large subunit (EC:1.7.99.4)	Ralstonia eutropha H16 Gene: H16_B0776: Assimilatory nitrate reductase, large subunit (EC:1.7.99.4)	Cupriavidus taiwanensis Gene: RALTA_B0610: Assimilatory nitrate reductase, large subunit (EC:1.7.99.4)	Assimilatory nitrate reductase, large subunit (EC:1.7.99.4)

CRON 4.
dppA	* Ralstonia solanacearum GMI1000 Site: position = -193 score = 4.59913 sequence = TGCACCAATTTGTGGCG Gene: RSc2870: Dipeptide ABC transporter, substrate-binding component	Ralstonia pickettii 12J	* Ralstonia metallidurans CH34 Site: position = -91 score = 4.27397 sequence = CGCACCAAAATGCGGCC Site: position = -218 score = 4.49333 sequence = CGCAGCATTGCGGGGCA Gene: Rmet_3158: Dipeptide ABC transporter, substrate-binding component	* Ralstonia eutropha JMP134 Site: position = -93 score = 4.896 sequence = CGCACCAAAATGCAGCG Gene: Reut_A3006: Dipeptide ABC transporter, substrate-binding component	* Ralstonia eutropha H16 Site: position = -93 score = 4.71663 sequence = CGCACCAAAACGCAGCG Gene: H16_A3298: Dipeptide ABC transporter, substrate-binding component	* Cupriavidus taiwanensis Site: position = -93 score = 4.63427 sequence = CGCACCAAAAAGCAGCG Gene: RALTA_A2753: Dipeptide ABC transporter, substrate-binding component	Dipeptide ABC transporter, substrate-binding component
dppB	Ralstonia solanacearum GMI1000 Gene: RSc2869: Dipeptide ABC transporter, permease component 1	Ralstonia pickettii 12J	Ralstonia metallidurans CH34 Gene: Rmet_3157: Dipeptide ABC transporter, permease component 1	Ralstonia eutropha JMP134 Gene: Reut_A3005: Dipeptide ABC transporter, permease component 1	Ralstonia eutropha H16 Gene: H16_A3297: Dipeptide ABC transporter, permease component 1	Cupriavidus taiwanensis Gene: RALTA_A2752: Dipeptide ABC transporter, permease component 1	Dipeptide ABC transporter, permease component 1
dppC	Ralstonia solanacearum GMI1000 Gene: RSc2868: Dipeptide ABC transporter, permease component 2	Ralstonia pickettii 12J	Ralstonia metallidurans CH34 Gene: Rmet_3156: Dipeptide ABC transporter, permease component 2	Ralstonia eutropha JMP134 Gene: Reut_A3004: Dipeptide ABC transporter, permease component 2	Ralstonia eutropha H16 Gene: H16_A3296: Dipeptide ABC transporter, permease component 2	Cupriavidus taiwanensis Gene: RALTA_A2751: Dipeptide ABC transporter, permease component 2	Dipeptide ABC transporter, permease component 2
dppD	Ralstonia solanacearum GMI1000 Gene: RSc2867: Dipeptide ABC transporter, ATP-binding component 1	Ralstonia pickettii 12J	Ralstonia metallidurans CH34 Gene: Rmet_3155: Dipeptide ABC transporter, ATP-binding component 1	Ralstonia eutropha JMP134 Gene: Reut_A3003: Dipeptide ABC transporter, ATP-binding component 1	Ralstonia eutropha H16 Gene: H16_A3295: Dipeptide ABC transporter, ATP-binding component 1	Cupriavidus taiwanensis Gene: RALTA_A2750: Dipeptide ABC transporter, ATP-binding component 1	Dipeptide ABC transporter, ATP-binding component 1
dppF	Ralstonia solanacearum GMI1000 Gene: RSc2866: Dipeptide ABC transporter, ATP-binding component 2	Ralstonia pickettii 12J	Ralstonia metallidurans CH34 Gene: Rmet_3154: Dipeptide ABC transporter, ATP-binding component 2	Ralstonia eutropha JMP134 Gene: Reut_A3002: Dipeptide ABC transporter, ATP-binding component 2	Ralstonia eutropha H16 Gene: H16_A3294: Dipeptide ABC transporter, ATP-binding component 2	Cupriavidus taiwanensis Gene: RALTA_A2749: Dipeptide ABC transporter, ATP-binding component 2	Dipeptide ABC transporter, ATP-binding component 2

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog NtrC - Ralstonia

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --