Statistics of regulated genes

Genome	Genes	Operons
Thermotoga maritima MSB8	3	1
Thermotoga sp. RQ2	3	1
Thermotoga neapolitana DSM 4359	3	1
Thermotoga petrophila RKU-1	3	1
Thermotoga naphthophila RKU-10	3	1
Thermotoga lettingae TMO	12	3
Thermosipho africanus TCF52B	32	3
Thermosipho melanesiensis BI429	35	4
Fervidobacterium nodosum Rt17-B1	14	3
Petrotoga mobilis SJ95	3	1
Thermotogales bacterium TBF 19.5.1	3	1

Clusters of co-Regulated Orthologous operoNs (CRONs)

Genes												Function
CRON 1.
btuF	* Thermotoga maritima MSB8 Site: position = -158 score = 95.04 sequence = GTATGATTTTCAAAT... Gene: TM0080: Vitamin B12 ABC transporter, B12-binding component BtuF	* Thermotoga sp. RQ2 Site: position = -253 score = 96.92 sequence = TATGATCTTCAAATA... Gene: TRQ2_0867: Vitamin B12 ABC transporter, B12-binding component BtuF	* Thermotoga neapolitana DSM 4359 Site: position = -219 score = 105.34 sequence = AACCTCCCTCACCGT... Gene: CTN_0612: Vitamin B12 ABC transporter, B12-binding component BtuF	* Thermotoga petrophila RKU-1 Site: position = -230 score = 93.04 sequence = AGCCTCCCTCACCGT... Gene: Tpet_0844: Vitamin B12 ABC transporter, B12-binding component BtuF	* Thermotoga naphthophila RKU-10 Site: position = -238 score = 93.04 sequence = GAAGCCTCCCTCACC... Gene: Tnap_0710: Vitamin B12 ABC transporter, B12-binding component BtuF	* Thermotoga lettingae TMO Site: position = -234 score = 113.23 sequence = TGAATAAGAAGCGTC... Gene: Tlet_1275: Vitamin B12 ABC transporter, B12-binding component BtuF	* Thermosipho africanus TCF52B Site: position = -241 score = 96.62 sequence = CTATTTGCAGCAACT... Gene: THA_254: Vitamin B12 ABC transporter, B12-binding component BtuF	* Thermosipho melanesiensis BI429 Site: position = -242 score = 99.39 sequence = TGATATAATTATGTT... Gene: Tmel_0038: Vitamin B12 ABC transporter, B12-binding component BtuF	* Fervidobacterium nodosum Rt17-B1 Site: position = -231 score = 96.84 sequence = AATAAACCTCCCTTT... Gene: Fnod_0257: Vitamin B12 ABC transporter, B12-binding component BtuF	* Petrotoga mobilis SJ95 Site: position = -232 score = 101.5 sequence = TAATATTTACTGCAT... Gene: Pmob_0038: Vitamin B12 ABC transporter, B12-binding component BtuF	* Thermotogales bacterium TBF 19.5.1 Site: position = -268 score = 100.27 sequence = TGATCCGATTTAAAG... Gene: Kole_1602: Vitamin B12 ABC transporter, B12-binding component BtuF	Vitamin B12 ABC transporter, B12-binding component BtuF
btuC	Thermotoga maritima MSB8 Gene: TM0079: Vitamin B12 ABC transporter, permease component BtuC	Thermotoga sp. RQ2 Gene: TRQ2_0868: Vitamin B12 ABC transporter, permease component BtuC	Thermotoga neapolitana DSM 4359 Gene: CTN_0613: Vitamin B12 ABC transporter, permease component BtuC	Thermotoga petrophila RKU-1 Gene: Tpet_0845: Vitamin B12 ABC transporter, permease component BtuC	Thermotoga naphthophila RKU-10 Gene: Tnap_0709: Vitamin B12 ABC transporter, permease component BtuC	Thermotoga lettingae TMO Gene: Tlet_1274: Vitamin B12 ABC transporter, permease component BtuC	Thermosipho africanus TCF52B Gene: THA_255: Vitamin B12 ABC transporter, permease component BtuC	Thermosipho melanesiensis BI429 Gene: Tmel_0039: Vitamin B12 ABC transporter, permease component BtuC	Fervidobacterium nodosum Rt17-B1 Gene: Fnod_0256: Vitamin B12 ABC transporter, permease component BtuC	Petrotoga mobilis SJ95 Gene: Pmob_0039: Vitamin B12 ABC transporter, permease component BtuC	Thermotogales bacterium TBF 19.5.1 Gene: Kole_1601: Vitamin B12 ABC transporter, permease component BtuC	Vitamin B12 ABC transporter, permease component BtuC
btuD	Thermotoga maritima MSB8 Gene: TM0078: Vitamin B12 ABC transporter, ATPase component BtuD	Thermotoga sp. RQ2 Gene: TRQ2_0869: Vitamin B12 ABC transporter, ATPase component BtuD	Thermotoga neapolitana DSM 4359 Gene: CTN_0614: Vitamin B12 ABC transporter, ATPase component BtuD	Thermotoga petrophila RKU-1 Gene: Tpet_0846: Vitamin B12 ABC transporter, ATPase component BtuD	Thermotoga naphthophila RKU-10 Gene: Tnap_0708: Vitamin B12 ABC transporter, ATPase component BtuD	Thermotoga lettingae TMO Gene: Tlet_1273: Vitamin B12 ABC transporter, ATPase component BtuD	Thermosipho africanus TCF52B Gene: THA_1650: Vitamin B12 ABC transporter, ATPase component BtuD	Thermosipho melanesiensis BI429 Gene: Tmel_1310: Vitamin B12 ABC transporter, ATPase component BtuD	Fervidobacterium nodosum Rt17-B1 Gene: Fnod_1090: Vitamin B12 ABC transporter, ATPase component BtuD	Petrotoga mobilis SJ95 Gene: Pmob_0040: Vitamin B12 ABC transporter, ATPase component BtuD	Thermotogales bacterium TBF 19.5.1 Gene: Kole_1600: Vitamin B12 ABC transporter, ATPase component BtuD	Vitamin B12 ABC transporter, ATPase component BtuD
CRON 2.
sucC	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	* Thermotoga lettingae TMO Site: position = -167 score = 133.29 sequence = TATGATTTTCCACCT... Gene: Tlet_1461: Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5)	Thermosipho africanus TCF52B	* Thermosipho melanesiensis BI429 Site: position = -242 score = 132.08 sequence = ATAACCAATGGAATA... Gene: Tmel_1870: Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5)	* Fervidobacterium nodosum Rt17-B1 Site: position = -261 score = 122.17 sequence = ATATTCCAAACTGCG... Gene: Fnod_1378: Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5)	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5)
sucD	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO Gene: Tlet_1462: Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5)	Thermosipho africanus TCF52B	Thermosipho melanesiensis BI429 Gene: Tmel_1871: Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5)	Fervidobacterium nodosum Rt17-B1 Gene: Fnod_1379: Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5)	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5)
THA_169	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_169: Predicted permease	Thermosipho melanesiensis BI429 Gene: Tmel_1872: Predicted permease	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Predicted permease
TM0177	Thermotoga maritima MSB8 Gene: TM0177: Predicted transmembrane protein	Thermotoga sp. RQ2 Gene: TRQ2_0771: Predicted transmembrane protein	Thermotoga neapolitana DSM 4359 Gene: CTN_0510: Predicted transmembrane protein	Thermotoga petrophila RKU-1 Gene: Tpet_0748: Predicted transmembrane protein	Thermotoga naphthophila RKU-10 Gene: Tnap_0807: Predicted transmembrane protein	Thermotoga lettingae TMO Gene: Tlet_0319: Predicted transmembrane protein	Thermosipho africanus TCF52B Gene: THA_289: Predicted transmembrane protein	Thermosipho melanesiensis BI429 Gene: Tmel_0072: Predicted transmembrane protein	Fervidobacterium nodosum Rt17-B1 Gene: Fnod_1380: Predicted transmembrane protein	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Predicted transmembrane protein
CRON 3.
cobT	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	* Thermotoga lettingae TMO Site: position = -582 score = 105.26 sequence = TGATAAAATAAATAT... Gene: Tlet_1236: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	*2 Thermosipho africanus TCF52B Site: position = -602 score = 112.02 sequence = AATATAGAAAACCAT... Gene: THA_1046: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) Site: position = -244 score = 131.17 sequence = ATAATGTTAACACCT... Gene: THA_1065: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	*2 Thermosipho melanesiensis BI429 Site: position = -219 score = 113.91 sequence = TATAAATTGTTACTA... Gene: Tmel_0854: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) Site: position = -233 score = 134.7 sequence = AATAATAAAACATCT... Gene: Tmel_0695: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	* Fervidobacterium nodosum Rt17-B1 Site: position = -265 score = 99.56 sequence = AAAAACAAACCGAAT... Gene: Fnod_1365: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1 Gene: Kole_0453: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)	Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21)
cbiX	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1066: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)	Thermosipho melanesiensis BI429 Gene: Tmel_0696: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
cbiC	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1067: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Thermosipho melanesiensis BI429 Gene: Tmel_0697: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
cbiD	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1068: Cobalt-precorrin-6 synthase, anaerobic	Thermosipho melanesiensis BI429 Gene: Tmel_0698: Cobalt-precorrin-6 synthase, anaerobic	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Cobalt-precorrin-6 synthase, anaerobic
cbiE	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1069: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)	Thermosipho melanesiensis BI429 Gene: Tmel_0699: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-)
cbiT	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1070: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Thermosipho melanesiensis BI429 Gene: Tmel_0700: Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
cbiL	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1071: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Thermosipho melanesiensis BI429 Gene: Tmel_0701: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
cbiF	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1072: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Thermosipho melanesiensis BI429 Gene: Tmel_0702: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
cbiG	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1073: Cobalamin biosynthesis protein CbiG	Thermosipho melanesiensis BI429 Gene: Tmel_0703: Cobalamin biosynthesis protein CbiG	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Cobalamin biosynthesis protein CbiG
cbiH	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1074: Cobalt-precorrin-3b C17-methyltransferase	Thermosipho melanesiensis BI429 Gene: Tmel_0704: Cobalt-precorrin-3b C17-methyltransferase	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Cobalt-precorrin-3b C17-methyltransferase
cbiJ	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1075: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	Thermosipho melanesiensis BI429 Gene: Tmel_0705: Cobalt-precorrin-6x reductase (EC 1.3.1.54)	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Cobalt-precorrin-6x reductase (EC 1.3.1.54)
hemA	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1076: Glutamyl-tRNA reductase (EC 1.2.1.70)	Thermosipho melanesiensis BI429 Gene: Tmel_0706: Glutamyl-tRNA reductase (EC 1.2.1.70)	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Glutamyl-tRNA reductase (EC 1.2.1.70)
hemC	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1077: Porphobilinogen deaminase (EC 2.5.1.61)	Thermosipho melanesiensis BI429 Gene: Tmel_0707: Porphobilinogen deaminase (EC 2.5.1.61)	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Porphobilinogen deaminase (EC 2.5.1.61)
cysG	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1078: cobA	Thermosipho melanesiensis BI429 Gene: Tmel_0708: cobA	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	cobA
hemB	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1079: Porphobilinogen synthase (EC 4.2.1.24)	Thermosipho melanesiensis BI429 Gene: Tmel_0709: Porphobilinogen synthase (EC 4.2.1.24)	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Porphobilinogen synthase (EC 4.2.1.24)
cysG1	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1080: Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Thermosipho melanesiensis BI429 Gene: Tmel_0710: Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4)
hemL	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1081: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)	Thermosipho melanesiensis BI429 Gene: Tmel_0711: Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Glutamate-1-semialdehyde aminotransferase (EC 5.4.3.8)
cbiM	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1082: Substrate-specific component CbiM of cobalt ECF transporter	Thermosipho melanesiensis BI429 Gene: Tmel_0712: Substrate-specific component CbiM of cobalt ECF transporter	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Substrate-specific component CbiM of cobalt ECF transporter
cbiN	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1083: Additional substrate-specific component CbiN of cobalt ECF transporter	Thermosipho melanesiensis BI429 Gene: Tmel_0713: Additional substrate-specific component CbiN of cobalt ECF transporter	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Additional substrate-specific component CbiN of cobalt ECF transporter
cbiQ	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1084: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Thermosipho melanesiensis BI429 Gene: Tmel_0714: Transmembrane component CbiQ of energizing module of cobalt ECF transporter	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Transmembrane component CbiQ of energizing module of cobalt ECF transporter
cbiO	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1085: ATPase component CbiO of energizing module of cobalt ECF transporter	Thermosipho melanesiensis BI429 Gene: Tmel_0715: ATPase component CbiO of energizing module of cobalt ECF transporter	Fervidobacterium nodosum Rt17-B1	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	ATPase component CbiO of energizing module of cobalt ECF transporter
Fnod_1372	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1086: Putative ATP binding protein	Thermosipho melanesiensis BI429 Gene: Tmel_0716: Putative ATP binding protein	Fervidobacterium nodosum Rt17-B1 Gene: Fnod_1372: Putative ATP binding protein	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Putative ATP binding protein
cobU	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO Gene: Tlet_1237: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Thermosipho africanus TCF52B Gene: THA_1045: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Thermosipho melanesiensis BI429 Gene: Tmel_0855: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Fervidobacterium nodosum Rt17-B1 Gene: Fnod_1366: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1 Gene: Kole_0454: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)	Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Tlet_1238	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO Gene: Tlet_1238: Putative xylose isomerase domain protein	Thermosipho africanus TCF52B Gene: THA_1044: Putative xylose isomerase domain protein	Thermosipho melanesiensis BI429 Gene: Tmel_0856: Putative xylose isomerase domain protein	Fervidobacterium nodosum Rt17-B1 Gene: Fnod_1367: Putative xylose isomerase domain protein	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1 Gene: Kole_0455: Putative xylose isomerase domain protein	Putative xylose isomerase domain protein
cobS	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO Gene: Tlet_1239: Cobalamin synthase	Thermosipho africanus TCF52B Gene: THA_1043: Cobalamin synthase	Thermosipho melanesiensis BI429 Gene: Tmel_0857: Cobalamin synthase	Fervidobacterium nodosum Rt17-B1 Gene: Fnod_1368: Cobalamin synthase	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1 Gene: Kole_0456: Cobalamin synthase	Cobalamin synthase
cbiP	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO	Thermosipho africanus TCF52B Gene: THA_1042: Cobyric acid synthase	Thermosipho melanesiensis BI429 Gene: Tmel_0858: Cobyric acid synthase	Fervidobacterium nodosum Rt17-B1 Gene: Fnod_1369: Cobyric acid synthase	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Cobyric acid synthase
cbiB	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO Gene: Tlet_1240: Adenosylcobinamide-phosphate synthase	Thermosipho africanus TCF52B Gene: THA_1041: Adenosylcobinamide-phosphate synthase	Thermosipho melanesiensis BI429 Gene: Tmel_0859: Adenosylcobinamide-phosphate synthase	Fervidobacterium nodosum Rt17-B1 Gene: Fnod_1370: Adenosylcobinamide-phosphate synthase	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	Adenosylcobinamide-phosphate synthase
cobD	Thermotoga maritima MSB8	Thermotoga sp. RQ2	Thermotoga neapolitana DSM 4359	Thermotoga petrophila RKU-1	Thermotoga naphthophila RKU-10	Thermotoga lettingae TMO Gene: Tlet_1241: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Thermosipho africanus TCF52B Gene: THA_1040: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Thermosipho melanesiensis BI429 Gene: Tmel_0860: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Fervidobacterium nodosum Rt17-B1 Gene: Fnod_1371: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)	Petrotoga mobilis SJ95	Thermotogales bacterium TBF 19.5.1	L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
btuR	Thermotoga maritima MSB8 Gene: TM1465: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Thermotoga sp. RQ2 Gene: TRQ2_1358: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Thermotoga neapolitana DSM 4359 Gene: CTN_1028: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Thermotoga petrophila RKU-1 Gene: Tpet_1328: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Thermotoga naphthophila RKU-10 Gene: Tnap_1345: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Thermotoga lettingae TMO Gene: Tlet_1242: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Thermosipho africanus TCF52B Gene: THA_1039: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Thermosipho melanesiensis BI429 Gene: Tmel_0861: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Fervidobacterium nodosum Rt17-B1 Gene: Fnod_1373: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Petrotoga mobilis SJ95 Gene: Pmob_1886: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Thermotogales bacterium TBF 19.5.1 Gene: Kole_0599: Cob(I)alamin adenosyltransferase (EC 2.5.1.17)	Cob(I)alamin adenosyltransferase (EC 2.5.1.17)

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD